G:8743

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Official Symbol TNFSF10
Aliases TL2, APO2L, CD253, TRAIL, Apo-2L
EntrezGene 8743
UniProt Coming Soon
Unique Molecular Interactions 29
Total Molecular Interactions 45
Total Single Events 249
Unique Interaction Partners 22

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to TNFSF10. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to TNFSF10. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to TNFSF10. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT146463 TNFSF10 Positive_regulation of NFKB1 2 0.08 2.45 0.71
2 INT146462 TNFSF10 Positive_regulation of Gene_expression of TNFRSF10D 1 0.27 1.45 0.71
3 INT194595 Binding of TNFSF10 and TNFRSF10B 4 0.15 9.3 0.53
4 INT330522 Binding of CD8A and TNFSF10 1 0.17 1.24 0.48
5 INT330515 TNFSF10 Regulation of Gene_expression of CD4 1 0.29 1.24 0.4
6 INT330518 TNFSF10 Regulation of CD4 1 0.29 1.24 0.4
7 INT194596 Binding of HLA-DRB4 and TNFSF10 3 0.08 6 0.38
8 INT330521 Binding of CD4 and TNFSF10 1 0.20 0.73 0.24
9 INT330520 Positive_regulation of Binding of CD8A and TNFSF10 1 0.19 0.62 0.21
10 INT175947 TNFSF10 Positive_regulation of Positive_regulation of CASP8 1 0.01 1.12 0.2
11 INT321410 EGR1 Negative_regulation of Gene_expression of TNFSF10 1 0.10 2.07 0.12
12 INT123461 Binding of TNFSF10 and Tnfrsf11b 1 0.00 1.34 0.08
13 INT237922 TNFSF10 Positive_regulation of CDKN1A 1 0.09 3.28 0.08
14 INT331576 IFN1@ Positive_regulation of TNFSF10 1 0.00 0.27 0.08
15 INT331575 Negative_regulation of IFN1@ Positive_regulation of TNFSF10 1 0.00 0.27 0.08
16 INT322560 Binding of TNFSF10 and DICER1 1 0.07 1.76 0.07
17 INT164128 TNFSF10 Positive_regulation of MAPK14 1 0.28 2.09 0.05
18 INT234382 Binding of TNF and TNFSF10 1 0.11 1.2 0.04
19 INT234383 Positive_regulation of Binding of TNF and TNFSF10 1 0.15 1.2 0.04
20 INT234622 IGFBP3 Positive_regulation of TNFSF10 1 0.56 1.08 0
21 INT322559 TNFSF10 Positive_regulation of CASP9 1 0.03 1.79 0
22 INT322558 Binding of AKT1 and TNFSF10 1 0.05 1.59 0
23 INT322561 Negative_regulation of TNFSF10 Positive_regulation of CASP9 1 0.03 1.15 0
24 INT322555 TNFSF10 Positive_regulation of MCL1 1 0.16 1.26 0
25 INT322596 Myc Negative_regulation of TNFSF10 Positive_regulation of BIRC3 1 0.12 1.38 0
26 INT322553 TNFSF10 Positive_regulation of CASP8 1 0.05 1.79 0
27 INT322557 TNFSF10 Positive_regulation of BIRC3 1 0.12 1.27 0
28 INT164129 TNFSF10 Positive_regulation of MAPK9 1 0.37 2.04 0
29 INT164130 TNFSF10 Positive_regulation of CDK20 1 0.50 1.06 0
30 INT329480 Binding of TNFRSF11B and TNFSF10 1 0.03 0.71 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 8743. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 8743. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116856 Gene_expression of TNFSF10 110 0.75 115.76 21.48
2 INT150528 Positive_regulation of Gene_expression of TNFSF10 26 0.67 30.71 5.43
3 INT149093 Positive_regulation of TNFSF10 31 0.49 34.61 4.56
4 INT104931 Binding of TNFSF10 15 0.36 17.44 2.07
5 INT125869 Regulation of Gene_expression of TNFSF10 5 0.38 8.77 1.9
6 INT125865 Regulation of TNFSF10 12 0.44 15.75 1.81
7 INT130771 Transcription of TNFSF10 3 0.51 3.4 1.74
8 INT130926 Negative_regulation of TNFSF10 9 0.36 10.18 1.3
9 INT130776 Positive_regulation of Transcription of TNFSF10 1 0.17 0.68 0.87
10 INT330523 Regulation of Binding of TNFSF10 1 0.36 1.21 0.39
11 INT166108 Localization of TNFSF10 5 0.64 3.58 0.33
12 INT166107 Negative_regulation of Gene_expression of TNFSF10 5 0.39 6.04 0.26
13 INT194601 Regulation of Localization of TNFSF10 1 0.38 0.25 0.1
14 INT237963 Positive_regulation of Localization of TNFSF10 1 0.10 0.95 0.08
15 INT322588 Regulation of Regulation of TNFSF10 1 0.13 0.79 0.04
16 INT237977 Positive_regulation of Positive_regulation of TNFSF10 1 0.10 2.47 0.03
17 INT350507 Positive_regulation of Binding of TNFSF10 1 0.05 0.59 0
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