G:920

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Official Symbol CD4
Aliases CD4mut
EntrezGene 920
UniProt Coming Soon
Unique Molecular Interactions 71
Total Molecular Interactions 109
Total Single Events 1038
Unique Interaction Partners 52

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to CD4. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to CD4. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to CD4. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53
2 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53
3 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85
4 INT174509 Binding of CD4 and CD28 1 0.26 1.68 0.84
5 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72
6 INT174500 Positive_regulation of Binding of CD4 and HLA-B 1 0.21 2.33 0.63
7 INT62299 Binding of CD4 and SGCG 1 0.39 1.23 0.51
8 INT251297 Binding of C2 and CD4 1 0.04 0.35 0.47
9 INT208461 Binding of CD4 and IL16 1 0.05 3.04 0.41
10 INT330515 TNFSF10 Regulation of Gene_expression of CD4 1 0.29 1.24 0.4
11 INT330518 TNFSF10 Regulation of CD4 1 0.29 1.24 0.4
12 INT273172 Negative_regulation of PDE4A Negative_regulation of Localization of CD4 1 0.11 0.74 0.37
13 INT226350 MBTPS1 Negative_regulation of Gene_expression of CD4 1 0.03 0.61 0.37
14 INT226374 Negative_regulation of Binding of CD4 and IFNA1 1 0.03 0.66 0.37
15 INT27030 HERPUD1 Regulation of CD4 1 0.41 0 0.34
16 INT188391 Binding of CD4 and HLA-DRB1 1 0.05 0.96 0.34
17 INT27037 HERPUD1 Regulation of Gene_expression of CD4 1 0.55 0 0.34
18 INT278693 ERAL1 Positive_regulation of CD4 1 0.05 1.1 0.31
19 INT278692 ERAL1 Positive_regulation of Positive_regulation of CD4 1 0.05 1.1 0.31
20 INT174499 Binding of CD4 and HLA-E 1 0.04 1.08 0.29
21 INT194670 CREB1 Regulation of Gene_expression of CD4 1 0.05 0.07 0.25
22 INT330521 Binding of CD4 and TNFSF10 1 0.20 0.73 0.24
23 INT352081 Binding of CD4 and ADAM11 1 0.09 0.33 0.24
24 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21
25 INT252821 Binding of CD4 and IL12A 1 0.02 1.36 0.19
26 INT188570 Negative_regulation of IRF6 Positive_regulation of CD4 1 0.04 0.19 0.19
27 INT188573 IRF6 Positive_regulation of CD4 1 0.05 0.19 0.19
28 INT274386 Binding of CD4 and ERVW-1 1 0.05 3.07 0.18
29 INT188569 Binding of CD4 and TLR4 1 0.16 0.34 0.16
30 INT10731 NEUROD1 Regulation of CD4 1 0.42 1.3 0.12
31 INT10730 CD9 Regulation of CD4 1 0.42 1.3 0.12
32 INT251295 Binding of CD4 and Regulation of ITIH4 1 0.11 0.24 0.11
33 INT241748 CCR5 Regulation of CD4 1 0.21 0.39 0.11
34 INT189144 MTNR1B Positive_regulation of Gene_expression of CD4 1 0.01 0.35 0.11
35 INT333099 Localization of IL2 Negative_regulation of Negative_regulation of CD4 1 0.14 0.8 0.09
36 INT292632 CD4 Positive_regulation of Gene_expression of IL9 1 0.24 0 0.09
37 INT333094 HIVEP1 Regulation of CD4 1 0.00 0.22 0.09
38 INT333089 CD4 Positive_regulation of ERVW-1 1 0.05 0.07 0.08
39 INT342288 Binding of CD4 and HFE 1 0.01 1.26 0.08
40 INT15953 Binding of CD4 and IgG2a 1 0.54 0.38 0.08
41 INT183768 Csf2 Regulation of CD4 1 0.37 0.52 0.08
42 INT333096 Binding of CD4 and IFN1@ 1 0.12 0.17 0.07
43 INT333092 Binding of CD4 and IL2 1 0.01 0.17 0.07
44 INT335715 Binding of FASLG and CD4 1 0.22 0.9 0.06
45 INT335714 Binding of FAS and CD4 1 0.38 0.9 0.06
46 INT333091 Localization of IFN1@ Negative_regulation of Negative_regulation of CD4 1 0.14 0.4 0.05
47 INT233303 Binding of CD4 and SRY 1 0.07 0.34 0.05
48 INT241751 Negative_regulation of Binding of CD4 and ITIH4 3 0.18 1.07 0.04
49 INT329102 Binding of CD4 and HLA-DQA2 2 0.04 0.92 0.04
50 INT283464 Binding of CD4 and DLAT 1 0.07 0.69 0.04
51 INT286968 Positive_regulation of STAT3 Regulation of Gene_expression of CD4 1 0.16 0.44 0.04
52 INT286962 IL2 Regulation of Gene_expression of CD4 1 0.01 0.45 0.04
53 INT212584 IFNA1 Regulation of Gene_expression of CD4 1 0.21 0.98 0.03
54 INT308540 CD4 Regulation of Localization of AGRP 1 0.39 0.85 0.03
55 INT221262 Binding of BRCA1 and CD4 1 0.22 0.81 0.03
56 INT326167 Binding of CD4 and Tmed8 1 0.47 0.29 0
57 INT260127 Binding of CD4 and Trav6-3 1 0.03 0 0
58 INT121649 Binding of CD4 and CXCL12 1 0.29 0.2 0
59 INT343501 CD4 Regulation of ERVW-1 1 0.09 0.16 0
60 INT240420 Myo5a Positive_regulation of CD4 1 0.06 0.27 0
61 INT277809 Binding of CD4 and CD40LG 1 0.15 0 0
62 INT329101 Binding of CD4 and INCENP 1 0.01 0.11 0
63 INT343499 CD4 Regulation of HIVEP1 1 0.02 0.16 0
64 INT205121 Binding of CD4 and CD7 1 0.05 0.51 0
65 INT340516 CD4 Regulation of IL2 1 0.04 0.32 0
66 INT258911 Binding of CD4 and HLA-G 1 0.04 0.06 0
67 INT235494 SFTPA1 Positive_regulation of Positive_regulation of CD4 1 0.01 0 0
68 INT275190 Localization of CD4 Positive_regulation of Positive_regulation of LCK 1 0.10 0.99 0
69 INT188750 Binding of CD4 and ADC 1 0.16 0.93 0
70 INT353129 Binding of CD4 and CXCR4 1 0.13 1.08 0
71 INT174502 HLA-B Regulation of CD4 1 0.13 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 920. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 920. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74
2 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31
3 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89
4 INT36287 Binding of CD4 96 0.47 58.93 11.88
5 INT16404 Regulation of CD4 54 0.61 33.05 10.29
6 INT17049 Localization of CD4 57 0.75 35.33 6.89
7 INT122653 Positive_regulation of Gene_expression of CD4 48 0.68 22.5 5.96
8 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6
9 INT174486 Regulation of Gene_expression of CD4 12 0.36 6.09 1.39
10 INT264171 Positive_regulation of Positive_regulation of CD4 5 0.49 4.74 0.94
11 INT189171 Positive_regulation of Localization of CD4 7 0.49 5.88 0.79
12 INT19218 Negative_regulation of Positive_regulation of CD4 9 0.41 9.21 0.69
13 INT202428 Positive_regulation of Binding of CD4 4 0.37 2.11 0.68
14 INT202427 Negative_regulation of Localization of CD4 2 0.32 3.1 0.56
15 INT202426 Transcription of CD4 6 0.69 3.96 0.49
16 INT260119 Regulation of Localization of CD4 2 0.44 1.61 0.46
17 INT260118 Regulation of Regulation of CD4 1 0.44 1.66 0.4
18 INT260110 Positive_regulation of Regulation of CD4 2 0.48 1.5 0.32
19 INT282775 Regulation of Positive_regulation of CD4 2 0.37 1.28 0.3
20 INT212592 Regulation of Binding of CD4 2 0.30 1.15 0.3
21 INT204183 Negative_regulation of Negative_regulation of CD4 3 0.30 1.79 0.22
22 INT296064 Positive_regulation of Transcription of CD4 1 0.28 0.11 0.21
23 INT20433 Regulation of Phosphorylation of CD4 1 0.06 0 0.13
24 INT20434 Phosphorylation of CD4 2 0.61 0 0.12
25 INT203282 Negative_regulation of Binding of CD4 2 0.30 0.63 0.11
26 INT273759 Positive_regulation of Negative_regulation of CD4 2 0.45 2.05 0
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