G:93759

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Official Symbol Sirt1
Aliases Sir2, Sir2a, SIR2L1, AA673258, MGC150273, Sir2alpha
EntrezGene 93759
UniProt Coming Soon
Unique Molecular Interactions 18
Total Molecular Interactions 28
Total Single Events 146
Unique Interaction Partners 11

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Sirt1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Sirt1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Sirt1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
2 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
3 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
4 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
5 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
6 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
7 INT256160 Positive_regulation of Binding of Pgc and Sirt1 1 0.55 0.21 0.07
8 INT256161 Binding of Pgc and Sirt1 1 0.38 0.21 0.07
9 INT340293 Binding of Ins1 and Sirt1 1 0.25 1.25 0.05
10 INT180040 Binding of D7Cwr3P and Sirt1 1 0.00 0 0
11 INT300696 Sirt1 Regulation of Cyb5r3 1 0.03 0 0
12 INT299444 Foxl2 Positive_regulation of Sirt1 1 0.24 0.31 0
13 INT289600 Negative_regulation of Binding of Sirt1 and Sirt1 1 0.47 1.17 0
14 INT299458 Gene_expression of Sirt1 Negative_regulation of Foxl2 1 0.25 0.32 0
15 INT256165 Binding of Sirt6 and Sirt1 1 0.13 0.58 0
16 INT289598 Binding of Sirt1 and Sirt1 1 0.41 1.15 0
17 INT314132 Sirt1 Positive_regulation of Ppargc1a 1 0.50 2.3 0
18 INT299451 Foxl2 Negative_regulation of Gene_expression of Sirt1 1 0.25 0.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 93759. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 93759. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
2 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
3 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
4 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
5 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
6 INT240935 Transcription of Sirt1 2 0.68 0.42 0.42
7 INT340290 Regulation of Transcription of Sirt1 1 0.43 0.13 0.42
8 INT240914 Negative_regulation of Sirt1 9 0.46 3.16 0.34
9 INT246620 Negative_regulation of Positive_regulation of Sirt1 2 0.39 1.9 0.17
10 INT256111 Regulation of Gene_expression of Sirt1 1 0.32 0.73 0.14
11 INT256136 Negative_regulation of Binding of Sirt1 1 0.30 0.5 0.07
12 INT256137 Positive_regulation of Regulation of Sirt1 1 0.36 0.32 0.05
13 INT256129 Negative_regulation of Gene_expression of Sirt1 1 0.31 0.4 0.05
14 INT270038 Positive_regulation of Positive_regulation of Sirt1 2 0.43 0.44 0.03
15 INT246622 Phosphorylation of Sirt1 2 0.74 0.56 0.03
16 INT256134 Localization of Sirt1 5 0.50 2.99 0
17 INT300686 Regulation of Binding of Sirt1 1 0.44 0.06 0
18 INT300683 Positive_regulation of Negative_regulation of Sirt1 1 0.45 0 0
19 INT240932 Negative_regulation of Transcription of Sirt1 1 0.34 0.29 0
20 INT300685 Positive_regulation of Binding of Sirt1 1 0.67 0 0
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