G:940

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Official Symbol CD28
Aliases Tp44, MGC138290
EntrezGene 940
UniProt Coming Soon
Unique Molecular Interactions 30
Total Molecular Interactions 63
Total Single Events 181
Unique Interaction Partners 20

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to CD28. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to CD28. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to CD28. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22
2 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12
3 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21
4 INT174509 Binding of CD4 and CD28 1 0.26 1.68 0.84
5 INT188567 IRF6 Positive_regulation of Gene_expression of CD28 1 0.05 1.28 0.82
6 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5
7 INT188565 IRF6 Regulation of Gene_expression of CD28 1 0.03 0.7 0.43
8 INT188572 CD14 Regulation of Gene_expression of CD28 1 0.11 0.6 0.4
9 INT353020 Binding of CD80 and Positive_regulation of Gene_expression of CD28 1 0.13 0.35 0.34
10 INT299791 Negative_regulation of Binding of CD28 and CTLA4 1 0.18 0.77 0.32
11 INT186127 CTLA4 Negative_regulation of CD28 1 0.19 0.74 0.32
12 INT289954 Binding of APC and CD28 1 0.03 0.38 0.28
13 INT289959 Negative_regulation of Binding of CD28 and CD80 1 0.07 0.24 0.23
14 INT288006 Binding of CD28 and LRRC23 1 0.02 0.54 0.19
15 INT188568 Negative_regulation of IRF6 Positive_regulation of CD28 1 0.05 0.19 0.19
16 INT171127 Binding of CD28 and IFN1@ 1 0.39 0.36 0.19
17 INT188571 IRF6 Positive_regulation of CD28 1 0.06 0.19 0.19
18 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18
19 INT194700 CD28 Positive_regulation of MAPK1 1 0.10 0.55 0.16
20 INT194806 MAPK1 Positive_regulation of CD28 Positive_regulation of Il4 1 0.08 0.42 0.13
21 INT194817 CD28 Positive_regulation of Il4 1 0.15 0.41 0.13
22 INT194717 CD28 Positive_regulation of IL13 1 0.03 0.41 0.13
23 INT293312 CTLA4 Negative_regulation of Binding of CD28 and CD80 1 0.01 0.29 0.12
24 INT351031 Binding of CD28 and CD96 1 0.02 0.36 0.09
25 INT194674 CD28 Negative_regulation of Gene_expression of IL13 1 0.02 0.06 0.08
26 INT270201 Binding of CD28 and Cd86 1 0.10 0.58 0.08
27 INT270203 Binding of CD28 and Apc 1 0.04 0.58 0.08
28 INT270202 Binding of CD28 and Cd80 1 0.09 0.58 0.08
29 INT194831 CD28 Positive_regulation of Gene_expression of Il4 1 0.15 0 0.06
30 INT288007 Binding of CD28 and CD40 1 0.05 0.51 0.03
31 INT211191 CD28 Positive_regulation of Gene_expression of IL2 1 0.15 0.15 0.03
32 INT277811 Binding of CD28 and DCPS 1 0.04 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 940. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 940. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT171134 Gene_expression of CD28 67 0.65 32.55 13.61
2 INT73504 Binding of CD28 35 0.45 15.99 10.04
3 INT116902 Positive_regulation of CD28 17 0.47 13.56 4.27
4 INT174527 Negative_regulation of CD28 13 0.35 5.06 2.65
5 INT144652 Negative_regulation of Binding of CD28 6 0.55 3.09 2.28
6 INT174511 Positive_regulation of Gene_expression of CD28 7 0.41 4.31 1.83
7 INT171133 Localization of CD28 8 0.71 3.42 1.48
8 INT279357 Regulation of Binding of CD28 1 0.18 0.3 0.72
9 INT188586 Negative_regulation of Gene_expression of CD28 6 0.34 1.9 0.69
10 INT270195 Positive_regulation of Positive_regulation of CD28 1 0.25 2.49 0.41
11 INT174476 Regulation of CD28 3 0.34 0.67 0.37
12 INT188577 Transcription of CD28 1 0.43 0.54 0.32
13 INT188583 Regulation of Transcription of CD28 1 0.22 0.54 0.32
14 INT171131 Protein_catabolism of CD28 1 0.73 0.47 0.27
15 INT278163 Negative_regulation of Localization of CD28 1 0.08 0.87 0.26
16 INT264194 Positive_regulation of Binding of CD28 1 0.23 0.22 0
17 INT270194 Regulation of Gene_expression of CD28 1 0.22 1.1 0
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