G:9518

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Official Symbol GDF15
Aliases PDF, MIC1, PLAB, MIC-1, NAG-1, PTGFB, GDF-15
EntrezGene 9518
UniProt Coming Soon
Unique Molecular Interactions 31
Total Molecular Interactions 46
Total Single Events 347
Unique Interaction Partners 17

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to GDF15. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to GDF15. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to GDF15. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT115147 TGM7 Positive_regulation of Gene_expression of GDF15 1 0.28 1.15 0.77
2 INT125523 PLAT Positive_regulation of GDF15 1 0.13 1.33 0.75
3 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
4 INT166953 LYRM4 Positive_regulation of Gene_expression of GDF15 1 0.10 1.6 0.51
5 INT159527 Binding of GDF15 and SLC17A5 1 0.14 1.15 0.51
6 INT125520 PLAT Positive_regulation of Gene_expression of GDF15 1 0.13 0.74 0.42
7 INT96787 SP1 Positive_regulation of GDF15 1 0.08 0.27 0.27
8 INT135947 MCC Regulation of GDF15 1 0.11 1.58 0.27
9 INT96790 SP3 Positive_regulation of GDF15 1 0.20 0.26 0.27
10 INT125515 SP1 Regulation of GDF15 1 0.14 0.47 0.26
11 INT125522 PLAT Regulation of Gene_expression of GDF15 1 0.08 0.46 0.26
12 INT125513 PLAT Positive_regulation of Transcription of GDF15 1 0.12 0.44 0.26
13 INT125521 EGR1 Regulation of GDF15 1 0.13 0.47 0.26
14 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
15 INT125517 Negative_regulation of PLAT Positive_regulation of GDF15 1 0.12 0.46 0.25
16 INT166954 LYRM4 Positive_regulation of GDF15 1 0.18 0.89 0.25
17 INT125512 Gene_expression of NFKB1 Positive_regulation of GDF15 1 0.32 0.42 0.25
18 INT108841 RXRG Positive_regulation of GDF15 1 0.41 0.58 0.24
19 INT125518 Binding of NFKB1 and GDF15 1 0.33 0.41 0.24
20 INT121581 Negative_regulation of PIK3CG Positive_regulation of GDF15 1 0.36 0.59 0.24
21 INT108842 RARA Positive_regulation of Gene_expression of GDF15 1 0.52 0.68 0.23
22 INT121583 Negative_regulation of GSK3A Negative_regulation of Gene_expression of GDF15 1 0.11 0.49 0.2
23 INT121580 PIK3CG Regulation of Gene_expression of GDF15 1 0.48 0.4 0.18
24 INT121582 AKT1 Regulation of Gene_expression of GDF15 1 0.21 0.4 0.18
25 INT159526 Regulation of Binding of GDF15 and SLC17A5 1 0.13 0.44 0.16
26 INT146025 EGR1 Negative_regulation of Gene_expression of GDF15 1 0.28 0.81 0.15
27 INT159525 SLC17A5 Positive_regulation of Gene_expression of GDF15 1 0.14 0.42 0.15
28 INT96791 NR2F2 Positive_regulation of GDF15 1 0.23 0.14 0.14
29 INT124618 IDO1 Positive_regulation of Gene_expression of GDF15 1 0.03 0.32 0.14
30 INT154803 Gene_expression of EGR1 Positive_regulation of Positive_regulation of GDF15 1 0.33 0.84 0.12
31 INT135948 MCC Regulation of Protein_catabolism of GDF15 1 0.09 0.77 0.09

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 9518. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 9518. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94388 Gene_expression of GDF15 124 0.77 79.48 31.42
2 INT101988 Positive_regulation of GDF15 71 0.69 51.03 18.56
3 INT94390 Positive_regulation of Gene_expression of GDF15 67 0.69 45.5 14.74
4 INT43356 Regulation of GDF15 13 0.59 8.27 3.63
5 INT96792 Regulation of Gene_expression of GDF15 10 0.61 5.74 3.21
6 INT108844 Positive_regulation of Positive_regulation of GDF15 11 0.68 7 2.74
7 INT115157 Negative_regulation of Gene_expression of GDF15 12 0.51 6.99 2.43
8 INT121593 Transcription of GDF15 4 0.61 2.87 1.19
9 INT124623 Binding of GDF15 4 0.35 2.06 1.09
10 INT101987 Negative_regulation of GDF15 4 0.36 3.18 1.04
11 INT121587 Positive_regulation of Transcription of GDF15 3 0.59 2.45 0.94
12 INT125591 Positive_regulation of Binding of GDF15 1 0.21 1.25 0.85
13 INT125527 Regulation of Positive_regulation of GDF15 2 0.33 0.91 0.48
14 INT135949 Protein_catabolism of GDF15 1 0.73 1.2 0.15
15 INT159528 Negative_regulation of Positive_regulation of GDF15 1 0.27 0.37 0.14
16 INT159530 Localization of GDF15 1 0.54 0.32 0.13
17 INT135950 Negative_regulation of Negative_regulation of GDF15 1 0.36 0.78 0.09
18 INT135951 Positive_regulation of Protein_catabolism of GDF15 1 0.41 0.44 0.06
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