G:9536

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Official Symbol PTGES
Aliases PGES, MPGES, PIG12, PP102, PP1294, MGST-IV, MGST1L1, TP53I12, mPGES-1, MGC10317, MGST1-L1
EntrezGene 9536
UniProt Coming Soon
Unique Molecular Interactions 36
Total Molecular Interactions 51
Total Single Events 322
Unique Interaction Partners 19

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to PTGES. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to PTGES. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to PTGES. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT155139 Binding of MC1R and PTGES 3 0.09 0 0.7
2 INT312106 EGR1 Regulation of Gene_expression of PTGES 1 0.31 1.06 0.64
3 INT147071 NFKB1 Regulation of Gene_expression of PTGES 1 0.36 0.35 0.57
4 INT136758 TNF Positive_regulation of Gene_expression of PTGES 1 0.05 0.52 0.55
5 INT312118 ELANE Regulation of PTGES 1 0.22 0.92 0.49
6 INT220193 PTGER2 Regulation of PTGES 1 0.06 0.66 0.41
7 INT144047 IL4 Positive_regulation of PTGES 1 0.29 0.43 0.37
8 INT144044 IRF6 Positive_regulation of PTGES 1 0.10 0.43 0.37
9 INT144043 IL13 Positive_regulation of PTGES 1 0.32 0.43 0.37
10 INT144046 IL13 Negative_regulation of Gene_expression of PTGES 1 0.30 0.48 0.35
11 INT312124 EGR1 Regulation of Binding of PTGES 1 0.31 0.41 0.35
12 INT144045 IFNG Negative_regulation of Gene_expression of PTGES 1 0.63 0.47 0.35
13 INT144050 IL4 Negative_regulation of Gene_expression of PTGES 1 0.27 0.48 0.35
14 INT144049 IL10 Negative_regulation of Gene_expression of PTGES 1 0.35 0.47 0.35
15 INT144048 IRF6 Positive_regulation of Gene_expression of PTGES 1 0.12 0.46 0.35
16 INT312119 ELANE Positive_regulation of Gene_expression of PTGES 1 0.18 0.74 0.33
17 INT136759 TNF Positive_regulation of PTGES 1 0.03 0.29 0.28
18 INT107615 IL1B Positive_regulation of PTGES 2 0.55 0.05 0.26
19 INT312115 ELANE Positive_regulation of Transcription of PTGES 1 0.25 0.53 0.25
20 INT105542 PTGES Positive_regulation of DNTT 1 0.00 0.62 0.25
21 INT139877 CPOX Regulation of Gene_expression of PTGES 1 0.17 0.07 0.18
22 INT139881 CPOX Regulation of Transcription of PTGES 1 0.17 0.07 0.18
23 INT314269 Binding of PTGES and PTGES3 1 0.12 0.68 0.18
24 INT312090 EGR1 Regulation of Positive_regulation of PTGES 1 0.42 0.21 0.18
25 INT139878 PTGES Regulation of Gene_expression of CPOX 1 0.17 0.07 0.18
26 INT139879 PTGES Regulation of Transcription of CPOX 1 0.17 0.07 0.18
27 INT312111 ELANE Regulation of Transcription of PTGES 1 0.22 0.23 0.16
28 INT350097 Gtf3a Regulation of Gene_expression of PTGES 1 0.00 0.25 0.13
29 INT147072 NFKB1 Regulation of PTGES 1 0.36 0 0.11
30 INT312094 ELANE Positive_regulation of PTGES 1 0.29 0.34 0.11
31 INT314267 Binding of CPOX and PTGES 1 0.03 0.34 0.09
32 INT312104 Binding of ALOX5 and PTGES 1 0.13 0.14 0.04
33 INT312125 Binding of ELANE and PTGES 1 0.13 0.07 0.03
34 INT312114 EGR1 Positive_regulation of Positive_regulation of PTGES 1 0.32 0 0
35 INT152541 CBX1 Negative_regulation of Gene_expression of PTGES 1 0.15 0.3 0
36 INT152542 ACF Negative_regulation of Gene_expression of PTGES 1 0.23 0.3 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 9536. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 9536. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT63419 Gene_expression of PTGES 109 0.77 40.83 23.67
2 INT91413 Negative_regulation of PTGES 35 0.58 17.94 12.03
3 INT91417 Positive_regulation of PTGES 36 0.68 18.45 7.64
4 INT98685 Positive_regulation of Gene_expression of PTGES 28 0.68 9.46 5.55
5 INT118926 Regulation of PTGES 17 0.51 5.79 4.69
6 INT107620 Binding of PTGES 25 0.48 5.49 4.24
7 INT108814 Regulation of Gene_expression of PTGES 8 0.59 3.62 3.54
8 INT134145 Negative_regulation of Gene_expression of PTGES 11 0.51 5.32 2.73
9 INT103238 Localization of PTGES 7 0.68 4.16 2.59
10 INT139885 Transcription of PTGES 4 0.68 1.46 1.12
11 INT91416 Negative_regulation of Positive_regulation of PTGES 3 0.40 1.88 0.82
12 INT144052 Positive_regulation of Regulation of PTGES 1 0.45 0.42 0.37
13 INT162900 Regulation of Negative_regulation of PTGES 1 0.14 0.72 0.37
14 INT169236 Negative_regulation of Binding of PTGES 2 0.36 0.37 0.36
15 INT147074 Positive_regulation of Transcription of PTGES 2 0.44 0.33 0.3
16 INT330901 Phosphorylation of PTGES 1 0.29 0.3 0.2
17 INT91414 Regulation of Positive_regulation of PTGES 1 0.14 0.28 0.19
18 INT312134 Regulation of Transcription of PTGES 1 0.40 0.18 0.13
19 INT164486 Positive_regulation of Negative_regulation of PTGES 1 0.41 0.15 0.07
20 INT154601 Protein_catabolism of PTGES 1 0.65 0.07 0.07
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