G:959

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Official Symbol CD40LG
Aliases IGM, IMD3, TRAP, gp39, CD154, CD40L, HIGM1, T-BAM, TNFSF5, hCD40L
EntrezGene 959
UniProt Coming Soon
Unique Molecular Interactions 32
Total Molecular Interactions 71
Total Single Events 751
Unique Interaction Partners 23

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to CD40LG. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to CD40LG. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to CD40LG. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01
2 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09
3 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
4 INT131853 CD40 Negative_regulation of Gene_expression of CD40LG 1 0.09 1.54 1.05
5 INT125234 Positive_regulation of Binding of BCR and CD40LG 1 0.31 0.76 0.86
6 INT125233 Binding of BCR and CD40LG 1 0.23 0.75 0.85
7 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
8 INT83424 Binding of CD40LG and ADIPOQ 2 0.13 1 0.59
9 INT83426 ADIPOQ Negative_regulation of Binding of CD40LG 2 0.21 1 0.59
10 INT83421 ADIPOQ Negative_regulation of Binding of CD40LG and ADIPOQ 1 0.08 0.5 0.29
11 INT191503 CD40LG Regulation of Gene_expression of F3 1 0.01 0.99 0.27
12 INT350016 Binding of CD40LG and ARID1B 1 0.01 3.26 0.21
13 INT322733 CD40LG Positive_regulation of Gene_expression of CD40 1 0.08 0.62 0.18
14 INT322734 Binding of CD40LG and Positive_regulation of CD40 1 0.07 0.62 0.18
15 INT111802 Binding of CD40LG and TFPI 1 0.14 0.62 0.16
16 INT85445 NUBPL Negative_regulation of Gene_expression of CD40LG 1 0.01 0.31 0.16
17 INT194576 Binding of ACLY and CD40LG 1 0.07 0.07 0.14
18 INT298476 CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12
19 INT298471 CD40LG Positive_regulation of CD80 1 0.04 0.33 0.12
20 INT298479 CD40LG Positive_regulation of CD40LG Positive_regulation of HLA-DRB1 1 0.00 0.33 0.12
21 INT298478 IL4 Positive_regulation of CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12
22 INT240770 Binding of CD40LG and F13A1 1 0.02 1.4 0.09
23 INT277807 CD40LG Regulation of CD40 1 0.21 0.17 0.08
24 INT328667 Binding of CD40LG and CSF2 1 0.16 0.59 0.05
25 INT234380 Negative_regulation of Binding of CD40 and CD40LG 1 0.16 1.4 0.04
26 INT344266 Binding of APOH and CD40LG 1 0.04 0.31 0
27 INT277809 Binding of CD4 and CD40LG 1 0.15 0 0
28 INT286653 Binding of CD40LG and OLR1 1 0.08 0.41 0
29 INT101943 Binding of CD40LG and HSD11B1 1 0.08 0.23 0
30 INT308702 Binding of AQP4 and CD40LG 1 0.10 0 0
31 INT336574 Binding of CD40LG and HCRTR1 1 0.05 0.1 0
32 INT83446 CD40LG Positive_regulation of Localization of CCL2 1 0.00 0.17 0
33 INT194926 Binding of CD40LG and Positive_regulation of BCR 1 0.04 0.39 0
34 INT194927 Binding of CD40LG and Positive_regulation of CD79B 1 0.01 0.4 0
35 INT147062 LAMC2 Negative_regulation of CD40LG 1 0.47 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 959. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 959. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23
2 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46
3 INT24816 Binding of CD40LG 68 0.47 45.48 11.56
4 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7
5 INT83451 Positive_regulation of Gene_expression of CD40LG 26 0.60 22.81 6.25
6 INT45753 Localization of CD40LG 45 0.79 32.31 5.28
7 INT5148 Regulation of CD40LG 25 0.44 21.58 4.05
8 INT125237 Negative_regulation of Gene_expression of CD40LG 16 0.54 9.9 3.27
9 INT51840 Positive_regulation of Localization of CD40LG 8 0.69 9.59 1.58
10 INT250281 Positive_regulation of Positive_regulation of CD40LG 3 0.23 3.19 0.73
11 INT130373 Regulation of Gene_expression of CD40LG 3 0.60 1.87 0.59
12 INT83435 Negative_regulation of Binding of CD40LG 2 0.39 0.96 0.55
13 INT236370 Positive_regulation of Phosphorylation of CD40LG 1 0.37 0.59 0.55
14 INT83436 Positive_regulation of Binding of CD40LG 3 0.33 0.85 0.49
15 INT153836 Phosphorylation of CD40LG 2 0.79 0.47 0.28
16 INT76125 Transcription of CD40LG 5 0.55 2.66 0.18
17 INT219192 Positive_regulation of Regulation of CD40LG 2 0.43 2.9 0.17
18 INT219164 Regulation of Positive_regulation of CD40LG 1 0.04 1.51 0.13
19 INT240780 Negative_regulation of Localization of CD40LG 2 0.24 0.72 0.1
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