G:9817

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Official Symbol KEAP1
Aliases INrf2, KLHL19, MGC1114, MGC4407, MGC9454, KIAA0132, MGC10630, MGC20887
EntrezGene 9817
UniProt Coming Soon
Unique Molecular Interactions 20
Total Molecular Interactions 46
Total Single Events 140
Unique Interaction Partners 8

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to KEAP1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to KEAP1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to KEAP1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29
2 INT101813 KEAP1 Negative_regulation of NFE2L2 3 0.47 1.63 0.28
3 INT101806 Binding of NFE2L2 and KEAP1 Positive_regulation of Gene_expression of GCLC 1 0.55 0.1 0.19
4 INT101812 Binding of KEAP1 and Positive_regulation of Gene_expression of GCLC 1 0.54 0.1 0.19
5 INT313308 Binding of SQSTM1 and KEAP1 1 0.46 1.16 0.1
6 INT313301 SQSTM1 Regulation of Protein_catabolism of KEAP1 1 0.43 0.58 0.1
7 INT101807 Gene_expression of KEAP1 Negative_regulation of Positive_regulation of GCLC 1 0.46 0 0.08
8 INT197545 KEAP1 Regulation of NFE2L2 3 0.49 0.8 0
9 INT313293 Binding of KEAP1 and GOPC 1 0.04 0.24 0
10 INT313298 Negative_regulation of SQSTM1 Positive_regulation of KEAP1 1 0.39 0.39 0
11 INT246061 KEAP1 Regulation of Positive_regulation of NFE2L2 1 0.34 0 0
12 INT246058 Binding of KEAP1 and Positive_regulation of NFE2L2 1 0.38 0 0
13 INT215414 KEAP1 Regulation of Regulation of NFE2L2 1 0.02 0.19 0
14 INT313299 Negative_regulation of Binding of NFE2L2 and KEAP1 1 0.24 0.14 0
15 INT197544 Binding of KEAP1 and KLHL2 1 0.02 0.43 0
16 INT197547 Binding of PTS and KEAP1 1 0.08 1.23 0
17 INT313296 Binding of KEAP1 and PGAM5 1 0.11 0.15 0
18 INT313290 Binding of NFE2L2 and Positive_regulation of Binding of NFE2L2 KEAP1 1 0.16 0.38 0
19 INT313310 KEAP1 Regulation of Gene_expression of SQSTM1 1 0.43 0.35 0
20 INT313311 SQSTM1 Positive_regulation of Positive_regulation of KEAP1 1 0.45 0 0
21 INT313306 KEAP1 Positive_regulation of SPARC 1 0.02 0.37 0
22 INT313294 Negative_regulation of SQSTM1 Positive_regulation of Positive_regulation of KEAP1 1 0.39 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 9817. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 9817. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT101815 Binding of KEAP1 6 0.44 5.29 0.39
2 INT101821 Localization of KEAP1 4 0.71 0.93 0.28
3 INT197575 Protein_catabolism of KEAP1 4 0.91 3.44 0.23
4 INT101820 Negative_regulation of KEAP1 20 0.58 18.79 0.19
5 INT101831 Gene_expression of KEAP1 21 0.77 10.82 0.12
6 INT197563 Regulation of KEAP1 10 0.56 3.18 0.11
7 INT313329 Positive_regulation of Binding of KEAP1 1 0.46 0.44 0.11
8 INT101824 Positive_regulation of Localization of KEAP1 2 0.57 0 0.09
9 INT101830 Negative_regulation of Localization of KEAP1 1 0.48 0 0.09
10 INT197562 Positive_regulation of KEAP1 16 0.63 6.78 0.08
11 INT101827 Positive_regulation of Gene_expression of KEAP1 5 0.69 2.67 0.08
12 INT197560 Negative_regulation of Gene_expression of KEAP1 5 0.58 3.12 0
13 INT313325 Regulation of Gene_expression of KEAP1 1 0.41 0 0
14 INT197556 Positive_regulation of Protein_catabolism of KEAP1 1 0.50 0.74 0
15 INT197574 Positive_regulation of Negative_regulation of KEAP1 1 0.50 1.15 0
16 INT313316 Regulation of Positive_regulation of KEAP1 1 0.41 0 0
17 INT197555 Transcription of KEAP1 1 0.71 2.33 0
18 INT197570 Negative_regulation of Transcription of KEAP1 1 0.58 1.19 0
19 INT313317 Positive_regulation of Positive_regulation of KEAP1 1 0.46 0 0
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