GO:0000045

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Name autophagic vacuole assembly
Categary Process
Go Slim No
Go Link GO:0000045
Unique Molecular Interactions 76
Total Molecular Interactions 111
Total Single Events 985
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for autophagic vacuole assembly. They are ordered first by their pain relevance and then by number of times they were reported for autophagic vacuole assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
2 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
3 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
4 INT157650 Phosphorylation of Prkcc Positive_regulation of Pik3c3 1 0.51 0 0.41
5 INT157647 Positive_regulation of Oprd1 Positive_regulation of Pik3c3 1 0.01 0 0.4
6 INT157649 Prkcc Regulation of Pik3c3 1 0.30 0 0.39
7 INT282397 Binding of Irgm1 and Atg16l1 1 0.17 1.18 0.39
8 INT157648 Binding of Prkcc and Pik3c3 1 0.39 0 0.36
9 INT213484 Binding of Lep and Pik3c3 1 0.01 0 0.35
10 INT60181 Binding of HTR5A and Pik3c3 1 0.03 0.1 0.29
11 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
12 INT91862 RPA1 Negative_regulation of Transcription of ATG9B 1 0.03 0.46 0.19
13 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
14 INT351427 Binding of PIK3C3 and RYR1 1 0.00 0 0.11
15 INT205204 LPA Positive_regulation of Positive_regulation of Pik3c3 1 0.02 0.22 0.09
16 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
17 INT193959 Psen1 Regulation of App 1 0.40 0.58 0.08
18 INT350213 Binding of Rab33b and Atg16l1 1 0.37 0.28 0.07
19 INT92584 Negative_regulation of PIK3C3 Negative_regulation of Gene_expression of PTGER2 1 0.01 0.46 0.07
20 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06
21 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
22 INT331227 Binding of Becn1 and Pink1 1 0.03 1.13 0.05
23 INT193967 Binding of PSEN1 and Psen1 1 0.41 1.2 0.05
24 INT193970 Binding of PSEN1 and Psen2 1 0.36 2.06 0.05
25 INT315986 Igf1 Positive_regulation of Pik3c3 1 0.00 0.48 0.05
26 INT356101 App Regulation of Negative_regulation of Psen1 1 0.23 0.31 0.04
27 INT331477 PSEN2 Regulation of Gene_expression of Psen1 1 0.00 0.15 0.03
28 INT296868 Binding of B4galnt2 and Map1lc3a 1 0.04 0.69 0.03
29 INT331478 Psen1 Regulation of Gene_expression of PSEN2 1 0.00 0.15 0.03
30 INT282995 Binding of Bcl2 and Becn1 21 0.03 9.8 0
31 INT283001 Binding of Becn1 and Om 1 0.00 0.1 0
32 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
33 INT335736 Binding of Map1lc3a and Map1lc3b 1 0.19 0.36 0
34 INT331226 Binding of Becn1 and Pik3c3 1 0.02 0.47 0
35 INT246799 Pik3c3 Positive_regulation of Negative_regulation of Ogg1 1 0.04 0 0
36 INT193962 Binding of Psen1 and Ncstn 1 0.13 0.08 0
37 INT331232 Binding of Atg12 and Atg16l1 1 0.03 0.08 0
38 INT334644 Binding of PSEN1 and TTN 1 0.01 0 0
39 INT160508 Binding of Ctsd and Tnfrsf1b 1 0.01 0 0
40 INT348531 Binding of BCL2 and BECN1 1 0.06 0.43 0
41 INT246789 Pik3c3 Regulation of Tsc2 1 0.02 0.34 0
42 INT283000 Negative_regulation of Binding of Bcl2 and Becn1 1 0.03 0.71 0
43 INT331225 Binding of Atg5 and Atg16l1 1 0.05 0.08 0
44 INT331230 Binding of Mapk8 and Becn1 1 0.02 0.77 0
45 INT193955 Binding of Psen1 and Psen2 1 0.37 1.64 0
46 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
47 INT331228 Atg5 Positive_regulation of Atg12 1 0.06 0.08 0
48 INT286331 Binding of Psen1 and Ror1 1 0.27 0 0
49 INT215133 Ighm Regulation of Gene_expression of Ctsd 1 0.25 0.26 0
50 INT193968 Binding of PSEN1 and Ps 1 0.07 0.66 0
51 INT283010 Regulation of Binding of Bcl2 and Becn1 1 0.03 1.45 0
52 INT262712 Psen1 Regulation of Gene_expression of Bace1 1 0.22 0.07 0
53 INT272014 Binding of RB1CC1 and Tsc1 1 0.05 0.44 0
54 INT283004 Binding of Becn1 and Pdss2 1 0.00 0.57 0
55 INT217400 Binding of Psen1 and Bace1 1 0.17 1.43 0
56 INT286337 PSENEN Regulation of Psen1 1 0.07 0.37 0
57 INT193958 Binding of Pld1 and Psen1 1 0.17 0 0
58 INT283008 Igkv1-131 Regulation of Binding of Becn1 1 0.01 0 0
59 INT246802 Pik3c3 Positive_regulation of Positive_regulation of Akt1 1 0.04 0 0
60 INT193953 Binding of Bcl2l1 and Psen1 1 0.07 0.66 0
61 INT215129 Ighg1 Regulation of Gene_expression of Ctsd 1 0.35 0.26 0
62 INT283014 Becn1 Regulation of Bcl2 1 0.03 0.88 0
63 INT193956 Binding of Psen1 and Rab6a 1 0.15 0 0
64 INT331479 Binding of PSEN2 and Psen1 1 0.00 0.07 0
65 INT215130 Ighg1 Regulation of Negative_regulation of Ctsd 1 0.21 0.27 0
66 INT215126 Ighm Regulation of Negative_regulation of Ctsd 1 0.15 0.27 0
67 INT313074 Binding of Bnip3 and Map1lc3a 1 0.01 0.26 0
68 INT234221 Negative_regulation of PSEN1 Negative_regulation of Gene_expression of APP 1 0.33 0.32 0
69 INT303338 Binding of ULK1 and Atg13 1 0.07 0.73 0
70 INT334645 Binding of PSEN1 and HM13 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for autophagic vacuole assembly. They are ordered first by their pain relevance and then by number of times they were reported in autophagic vacuole assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
2 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
3 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
4 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
5 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
6 INT60174 Positive_regulation of Pik3c3 12 0.67 1.05 3.23
7 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
8 INT163544 Binding of Psen1 40 0.36 15.28 2.42
9 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
10 INT157305 Gene_expression of Map1lc3a 47 0.75 18.04 1.93
11 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
12 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
13 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
14 INT94572 Negative_regulation of Pik3c3 5 0.13 1.37 1.41
15 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
16 INT166628 Positive_regulation of Gene_expression of Becn1 2 0.67 1.03 1.23
17 INT166632 Gene_expression of Becn1 2 0.75 1.02 1.22
18 INT148027 Localization of Pik3c3 1 0.24 0.34 1.17
19 INT157642 Gene_expression of Pik3c3 7 0.75 0.68 1.08
20 INT150942 Regulation of Pik3c3 2 0.18 0.96 0.94
21 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
22 INT166630 Negative_regulation of Localization of Becn1 1 0.41 0.51 0.88
23 INT166626 Localization of Becn1 1 0.76 0.5 0.87
24 INT166633 Binding of Becn1 1 0.45 0.5 0.86
25 INT166629 Negative_regulation of Binding of Becn1 1 0.41 0.5 0.86
26 INT157303 Positive_regulation of Gene_expression of Map1lc3a 15 0.53 4.12 0.85
27 INT166631 Positive_regulation of Becn1 1 0.41 0.52 0.84
28 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
29 INT157302 Positive_regulation of Map1lc3a 27 0.66 11.31 0.79
30 INT157643 Phosphorylation of Pik3c3 1 0.78 0 0.79
31 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
32 INT282380 Binding of Atg16l1 4 0.38 2.06 0.58
33 INT64454 Positive_regulation of Ctsd 2 0.44 1.14 0.57
34 INT217394 Regulation of Binding of PSEN1 1 0.44 1.58 0.53
35 INT157638 Positive_regulation of Gene_expression of Pik3c3 2 0.48 0.46 0.52
36 INT205200 Positive_regulation of Pik3c3 7 0.08 2.76 0.51
37 INT157645 Negative_regulation of Pik3c3 6 0.41 2.88 0.5
38 INT157300 Negative_regulation of Positive_regulation of Map1lc3a 1 0.00 0.61 0.45
39 INT157306 Positive_regulation of Positive_regulation of Map1lc3a 3 0.35 1.21 0.44
40 INT234249 Regulation of PSEN1 6 0.37 2.21 0.43
41 INT234257 Regulation of Gene_expression of PSEN1 6 0.44 1.98 0.42
42 INT193856 Localization of Psen1 19 0.73 9.79 0.41
43 INT157301 Negative_regulation of Map1lc3a 5 0.28 3.2 0.41
44 INT47094 Negative_regulation of Ctsd 2 0.56 2.54 0.41
45 INT157639 Negative_regulation of Positive_regulation of Pik3c3 1 0.41 0 0.41
46 INT157644 Negative_regulation of Phosphorylation of Pik3c3 1 0.41 0 0.4
47 INT157640 Positive_regulation of Phosphorylation of Pik3c3 1 0.48 0 0.4
48 INT157641 Regulation of Pik3c3 1 0.59 0 0.39
49 INT312037 Gene_expression of BECN1 2 0.33 1.5 0.37
50 INT177773 Localization of PSEN1 4 0.73 0.89 0.36
51 INT237038 Gene_expression of Becn1 18 0.36 13.68 0.31
52 INT316045 Negative_regulation of Negative_regulation of Psen1 1 0.42 1.58 0.27
53 INT261676 Negative_regulation of Positive_regulation of PSEN1 1 0.36 1.59 0.25
54 INT222130 Gene_expression of Pik3c3 3 0.12 0.62 0.21
55 INT276186 Negative_regulation of Gene_expression of Pik3c3 1 0.07 0.3 0.21
56 INT254878 Localization of Map1lc3a 5 0.57 3.32 0.2
57 INT181508 Regulation of Regulation of Psen1 2 0.33 0.51 0.2
58 INT346897 Positive_regulation of Atg16l1 1 0.16 0.57 0.19
59 INT91867 Transcription of ATG9B 1 0.03 0.46 0.19
60 INT346898 Regulation of Binding of Atg16l1 1 0.09 0.75 0.19
61 INT92586 Negative_regulation of PIK3C3 2 0.03 0.73 0.18
62 INT286317 Positive_regulation of Transcription of Psen1 1 0.37 0.32 0.17
63 INT160505 Gene_expression of Ctsd 1 0.73 2.57 0.15
64 INT165481 Negative_regulation of Gene_expression of Map1lc3a 7 0.45 2.55 0.14
65 INT336359 Positive_regulation of Phosphorylation of Psen1 1 0.33 0.4 0.13
66 INT336361 Phosphorylation of Psen1 1 0.54 0.34 0.13
67 INT351430 Binding of PIK3C3 1 0.01 0 0.11
68 INT201694 Negative_regulation of Gene_expression of PSEN1 3 0.41 2.31 0.1
69 INT215119 Binding of Ctsd 1 0.35 0.66 0.1
70 INT215115 Regulation of Regulation of Ctsd 1 0.25 0.66 0.1
71 INT221200 Positive_regulation of Positive_regulation of Pik3c3 1 0.04 0.07 0.1
72 INT215114 Regulation of Ctsd 1 0.25 0.66 0.1
73 INT273285 Negative_regulation of Localization of Psen1 1 0.36 0.99 0.09
74 INT193862 Positive_regulation of Positive_regulation of Psen1 3 0.49 0.9 0.08
75 INT193872 Positive_regulation of Localization of Psen1 3 0.49 1.39 0.08
76 INT261678 Positive_regulation of Positive_regulation of PSEN1 1 0.42 0.62 0.08
77 INT193890 Regulation of Positive_regulation of Psen1 1 0.44 0.66 0.08
78 INT193938 Phosphorylation of PSEN1 5 0.79 1.6 0.07
79 INT282981 Positive_regulation of Gene_expression of Becn1 8 0.13 6.2 0.06
80 INT193859 Negative_regulation of Binding of Psen1 3 0.42 1.85 0.05
81 INT331406 Negative_regulation of Regulation of Psen1 1 0.04 0.09 0.05
82 INT282985 Negative_regulation of Becn1 11 0.20 7.72 0.04
83 INT193865 Protein_catabolism of Psen1 10 0.97 0.37 0.04
84 INT282977 Regulation of Becn1 4 0.25 2.29 0.04
85 INT246821 Binding of Pik3c3 1 0.02 0.26 0.04
86 INT246820 Negative_regulation of Binding of Pik3c3 1 0.02 0.26 0.04
87 INT254873 Regulation of Map1lc3a 5 0.58 1.24 0.03
88 INT282982 Binding of Map1lc3a 4 0.28 1.77 0.03
89 INT296863 Regulation of Binding of Map1lc3a 1 0.35 0.71 0.03
90 INT282974 Binding of Becn1 24 0.07 7.43 0
91 INT282990 Negative_regulation of Binding of Becn1 6 0.08 1.44 0
92 INT282967 Negative_regulation of Gene_expression of Becn1 3 0.08 2.04 0
93 INT254879 Binding of Atg5 3 0.27 0.26 0
94 INT303277 Protein_catabolism of Map1lc3a 3 0.94 0.31 0
95 INT331187 Positive_regulation of Becn1 2 0.09 1.01 0
96 INT215121 Regulation of Gene_expression of Map1lc3a 2 0.35 0.77 0
97 INT282988 Regulation of Binding of Becn1 2 0.05 0 0
98 INT215123 Positive_regulation of Negative_regulation of Ctsd 1 0.44 0 0
99 INT282978 Positive_regulation of Binding of Becn1 1 0.04 0 0
100 INT246778 Positive_regulation of Positive_regulation of Pik3c3 1 0.06 0 0
101 INT331186 Binding of Atg13 1 0.10 0.09 0
102 INT286327 Regulation of Binding of Psen1 1 0.33 0.16 0
103 INT308844 Phosphorylation of Map1lc3a 1 0.77 0 0
104 INT234250 Positive_regulation of Negative_regulation of PSEN1 1 0.41 0 0
105 INT331196 Positive_regulation of Phosphorylation of Atg13 1 0.14 0.25 0
106 INT193886 Regulation of Protein_catabolism of Psen1 1 0.44 0.06 0
107 INT331192 Negative_regulation of Atg13 1 0.12 0.1 0
108 INT254874 Negative_regulation of Localization of Map1lc3a 1 0.18 1.05 0
109 INT246766 Positive_regulation of Gene_expression of Pik3c3 1 0.04 0.32 0
110 INT193934 Positive_regulation of Binding of PSEN1 1 0.49 0.92 0
111 INT297996 Negative_regulation of ATG9B 1 0.21 0.22 0
112 INT306663 Negative_regulation of Atg5 1 0.10 0.28 0
113 INT348466 Positive_regulation of Gene_expression of BECN1 1 0.22 0.76 0
114 INT331407 Negative_regulation of Transcription of Psen1 1 0.04 0.08 0
115 INT348470 Binding of BECN1 1 0.11 0.42 0
116 INT208050 Localization of PIK3C3 1 0.01 0.13 0
117 INT177774 Transcription of PSEN1 1 0.33 0.09 0
118 INT331191 Negative_regulation of Phosphorylation of Atg13 1 0.12 0.1 0
119 INT325712 Regulation of Gene_expression of Becn1 1 0.03 0.35 0
120 INT208038 Regulation of PIK3C3 1 0.00 0.64 0
121 INT296860 Gene_expression of Atg12 1 0.36 1.56 0
122 INT331182 Phosphorylation of Atg13 1 0.23 0.25 0
123 INT193844 Positive_regulation of Protein_catabolism of Psen1 1 0.49 0.05 0
124 INT282969 Protein_catabolism of Becn1 1 0.08 0 0
125 INT331183 Binding of Atg12 1 0.12 0.08 0
126 INT234258 Negative_regulation of Phosphorylation of PSEN1 1 0.35 0.49 0
127 INT296854 Gene_expression of Atg5 1 0.38 1.55 0
128 INT308846 Negative_regulation of Protein_catabolism of Map1lc3a 1 0.41 0.06 0
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