GO:0000060

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Name protein import into nucleus, translocation
Categary Process
Go Slim No
Go Link GO:0000060
Unique Molecular Interactions 2740
Total Molecular Interactions 3604
Total Single Events 32619
Pain Genes Associated 29

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein import into nucleus, translocation. They are ordered first by their pain relevance and then by number of times they were reported for protein import into nucleus, translocation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT21276 Binding of Oprd1 and Penk 9 0.54 1.14 8.28
3 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
4 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
5 INT40114 Binding of OPRD1 and Oprm1 2 0.00 0 4.29
6 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18
7 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
8 INT249566 Binding of Oprd1 and Psmd1 1 0.01 0.82 3.8
9 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
10 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
11 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
12 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
13 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
14 INT137230 Trh Regulation of Gene_expression of Oprd1 1 0.01 1.62 2.75
15 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
16 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
17 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
18 INT150596 Binding of Oprd1 and Oprk1 1 0.08 0.14 2.59
19 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
20 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
21 INT69665 Binding of Oprd1 and Pnoc 5 0.35 0.4 2.5
22 INT249567 Positive_regulation of Binding of Oprd1 and Psmd1 1 0.01 0.66 2.5
23 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
24 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
25 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
26 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
27 INT131257 ITIH4 Positive_regulation of Gene_expression of Nfkbia 1 0.23 1.41 2.3
28 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
29 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
30 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
31 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
32 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
33 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
34 INT5486 Oprd1 Regulation of Cck 1 0.21 0 2.16
35 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
36 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
37 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
38 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
39 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
40 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
41 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
42 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
43 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
44 INT68272 Binding of Oprd1 and G2e3 1 0.00 0.11 1.93
45 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
46 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84
47 INT119917 Zfp821 Positive_regulation of Positive_regulation of Oprd1 1 0.01 0 1.82
48 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
49 INT70225 oh Regulation of Oprd1 1 0.20 0.13 1.8
50 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
51 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
52 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
53 INT129953 Oprd1 Regulation of Cspg5 1 0.17 0.15 1.74
54 INT37840 Binding of Cyp27b1 and Oprd1 1 0.01 0 1.73
55 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
56 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
57 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
58 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
59 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
60 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
61 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.17 0.38 1.65
62 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.10 0.38 1.64
63 INT61049 Binding of Oprd1 and Negative_regulation of Gene_expression of Odc1 1 0.21 0 1.64
64 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
65 INT61674 Gpm6a Regulation of Oprd1 1 0.01 0.07 1.62
66 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
67 INT335405 Binding of Arntl and Npas2 1 0.28 1.82 1.61
68 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
69 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
70 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
71 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
72 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
73 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54
74 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
75 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
76 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
77 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
78 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
79 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
80 INT317509 Oprm1 Negative_regulation of Phosphorylation of Oprd1 1 0.00 0 1.46
81 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
82 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
83 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
84 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
85 INT329451 Binding of Oprd1 and Tacr1 1 0.05 0.23 1.41
86 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
87 INT142852 Oprm1 Positive_regulation of Oprd1 1 0.41 0.06 1.41
88 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
89 INT329452 Binding of Tac1 and Oprd1 1 0.01 0.23 1.4
90 INT6466 Binding of Npr1 and Oprd1 1 0.01 0 1.37
91 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
92 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
93 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
94 INT249565 Binding of Gabrg1 and Oprd1 1 0.00 0.1 1.33
95 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
96 INT13756 Binding of Oprd1 and Scn4a 1 0.02 0 1.32
97 INT13755 Binding of Oprd1 and Ap2m1 1 0.20 0 1.32
98 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31
99 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
100 INT57263 Binding of Oprd1 and Atxn2l 1 0.02 0 1.29
101 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
102 INT57262 Binding of Gria4 and Oprd1 1 0.06 0 1.29
103 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
104 INT34393 Oprd1 Negative_regulation of Adcy1 1 0.36 0 1.27
105 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
106 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
107 INT63864 Oprd1 Regulation of Localization of Prl 2 0.16 0 1.23
108 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
109 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
110 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
111 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
112 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
113 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
114 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
115 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
116 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
117 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
118 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
119 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
120 INT13203 Oprd1 Negative_regulation of Akr1d1 1 0.01 0 1.18
121 INT13205 Oprd1 Negative_regulation of Npr1 2 0.01 0 1.16
122 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
123 INT326665 Cpe Positive_regulation of Oprd1 1 0.01 1.24 1.15
124 INT199493 Ngf Regulation of Oprd1 1 0.05 1.05 1.15
125 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
126 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
127 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
128 INT21267 Cck Negative_regulation of Binding of Oprd1 1 0.50 0 1.12
129 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
130 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
131 INT69338 Binding of Oprd1 and Oprm1 1 0.24 0.26 1.11
132 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
133 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
134 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
135 INT122889 Ifng Positive_regulation of Gene_expression of HLA-E 1 0.02 0.97 1.1
136 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
137 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
138 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
139 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
140 INT60783 Binding of Oprd1 and Cck 1 0.26 0.47 1.09
141 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
142 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
143 INT108547 AKT1 Regulation of MAPKAPK5 1 0.04 1.2 1.08
144 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
145 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
146 INT121089 Binding of Oprd1 and Adarb1 2 0.06 0 1.07
147 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
148 INT145407 Oprd1 Regulation of Positive_regulation of Dbi 1 0.17 0 1.07
149 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
150 INT6415 Binding of Cpe and Oprd1 1 0.00 0 1.07
151 INT87222 Nrg1 Regulation of Oprd1 1 0.00 0 1.07
152 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
153 INT122432 Prkci Regulation of Negative_regulation of Oprd1 1 0.01 0 1.06
154 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
155 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
156 INT108413 Binding of OPRK1 and Oprd1 1 0.00 0.08 1.04
157 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
158 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
159 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
160 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
161 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
162 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
163 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
164 INT150621 Binding of Oprm1 and Oprd1 1 0.00 0.08 1.02
165 INT79602 Binding of PSMA5 and Oprd1 2 0.19 1.05 1.01
166 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
167 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
168 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
169 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
170 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
171 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
172 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
173 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
174 INT94493 Avp Positive_regulation of Gene_expression of Ifng 1 0.05 1.73 0.97
175 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
176 INT18890 Penk Regulation of Oprd1 1 0.25 0.45 0.97
177 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
178 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
179 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
180 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
181 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
182 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
183 INT77142 Binding of IFNG and IL4 2 0.03 1.16 0.95
184 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
185 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
186 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
187 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
188 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
189 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
190 INT65463 Bri3 Negative_regulation of Oprd1 1 0.10 0.39 0.94
191 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
192 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
193 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
194 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
195 INT82126 CEBPB Regulation of Gene_expression of Oprd1 1 0.00 0 0.93
196 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
197 INT82124 IK Positive_regulation of Gene_expression of Oprd1 1 0.00 0 0.92
198 INT94501 Il2 Positive_regulation of Gene_expression of Ifng 1 0.03 1.63 0.92
199 INT85879 Il12a Positive_regulation of Gene_expression of Ifng 1 0.20 0.89 0.92
200 INT34271 Positive_regulation of WAS Positive_regulation of Oprd1 1 0.01 0 0.91

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein import into nucleus, translocation. They are ordered first by their pain relevance and then by number of times they were reported in protein import into nucleus, translocation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5660 Binding of Oprd1 477 0.48 71.86 342.06
3 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
5 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32
6 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41
7 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
8 INT6852 Localization of TNF 883 0.81 705.95 270.84
9 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9
10 INT6481 Binding of TNF 624 0.48 510.2 214.82
11 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
12 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
13 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11
14 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
15 INT9660 Regulation of TNF 363 0.62 312.94 139.99
16 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
17 INT12569 Localization of Oprd1 94 0.81 23.81 104.56
18 INT10166 Localization of Tnf 237 0.81 153.95 88.64
19 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
20 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
21 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
22 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
23 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
24 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
25 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
26 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
27 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
28 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
29 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
30 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
31 INT6116 Regulation of Gene_expression of Oprd1 69 0.62 16.43 54
32 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
33 INT10668 Positive_regulation of Gene_expression of Oprd1 61 0.69 15.21 52.12
34 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
35 INT32718 Gene_expression of OPRD1 82 0.76 9.43 48.38
36 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
37 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
38 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
39 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
40 INT7828 Positive_regulation of Oprd1 55 0.69 14.11 42.86
41 INT13354 Transcription of TNF 108 0.72 85.81 42.32
42 INT6067 Positive_regulation of Positive_regulation of Oprd1 37 0.69 6.56 36.58
43 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
44 INT34465 Regulation of Oprd1 34 0.45 7.14 34.29
45 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
46 INT35406 Localization of Tnf 94 0.81 64.63 31.65
47 INT12397 Gene_expression of Oprd1 53 0.78 9.1 31.31
48 INT15000 Transcription of Oprd1 32 0.72 5.7 29.22
49 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
50 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
51 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
52 INT5771 Binding of Oprd1 37 0.48 2.6 27.54
53 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
54 INT6382 Regulation of Binding of Oprd1 36 0.61 7 26.48
55 INT6934 Binding of OPRD1 51 0.48 7.72 25.73
56 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
57 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
58 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
59 INT5690 Negative_regulation of Binding of Oprd1 36 0.59 8.29 24.52
60 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
61 INT8518 Localization of Ifng 53 0.81 36.68 24.13
62 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
63 INT30386 Negative_regulation of OPRD1 33 0.52 4.34 23.06
64 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
65 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
66 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
67 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
68 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
69 INT31393 Positive_regulation of Localization of Oprd1 10 0.66 7.32 21.23
70 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
71 INT27529 Phosphorylation of Oprd1 23 0.47 1.16 20.18
72 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
73 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
74 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58
75 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
76 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
77 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
78 INT19509 Localization of Ifng 55 0.78 28.25 18.67
79 INT31905 Positive_regulation of Binding of Oprd1 21 0.66 3.31 18.44
80 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
81 INT8332 Positive_regulation of OPRD1 30 0.61 3.88 17.65
82 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
83 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15
84 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
85 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
86 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
87 INT6066 Negative_regulation of Positive_regulation of Oprd1 15 0.43 1.36 16.63
88 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
89 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
90 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
91 INT4769 Regulation of OPRD1 20 0.44 2.05 15.97
92 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89
93 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
94 INT10360 Positive_regulation of Ifng 33 0.68 21.73 15.19
95 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
96 INT29352 Negative_regulation of Oprd1 16 0.58 6.51 14.6
97 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
98 INT54284 Negative_regulation of Gene_expression of Oprd1 16 0.42 4.56 14.34
99 INT10173 Binding of Tnf 45 0.48 35.6 14.32
100 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
101 INT4931 Localization of IFNG 53 0.78 33.25 13.65
102 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
103 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
104 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14
105 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
106 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
107 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3
108 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
109 INT9160 Negative_regulation of Ifng 31 0.58 16.37 11.84
110 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
111 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91
112 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
113 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
114 INT81538 Phosphorylation of Nfkbia 27 0.62 8.86 10.49
115 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
116 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
117 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
118 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
119 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
120 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
121 INT80872 Protein_catabolism of Nfkbia 28 0.92 10.56 8.62
122 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
123 INT95297 Gene_expression of Nfkbia 14 0.68 7.61 8.24
124 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
125 INT31394 Negative_regulation of Localization of Oprd1 3 0.39 2.38 7.89
126 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
127 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
128 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
129 INT68299 Binding of Tnf 17 0.39 12.55 7.49
130 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
131 INT81532 Negative_regulation of Protein_catabolism of Nfkbia 21 0.54 8.92 7.38
132 INT20845 Positive_regulation of Negative_regulation of Oprd1 7 0.70 1.81 7.33
133 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
134 INT6239 Regulation of Regulation of Oprd1 7 0.45 0.34 7.26
135 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
136 INT5311 Regulation of Negative_regulation of Oprd1 11 0.43 0.99 7.23
137 INT93481 Negative_regulation of Protein_catabolism of Nfkbia 14 0.39 7.24 7.21
138 INT5326 Regulation of Ifng 12 0.55 4.56 7.19
139 INT88498 Protein_catabolism of Nfkbia 14 0.82 6.94 7.1
140 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
141 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
142 INT81541 Negative_regulation of Nfkbia 12 0.51 5.73 6.79
143 INT54062 Transcription of Oprd1 11 0.68 1.05 6.65
144 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
145 INT54747 Localization of OPRD1 7 0.73 0.69 6.27
146 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
147 INT74154 Transcription of Ifng 14 0.67 10.33 6.21
148 INT88245 Gene_expression of Slc11a1 42 0.53 18.86 6.2
149 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
150 INT91575 Positive_regulation of Phosphorylation of Oprd1 8 0.02 0.23 6.07
151 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
152 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
153 INT15803 Regulation of IFNG 21 0.44 12.57 5.98
154 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
155 INT5186 Regulation of Ifng 11 0.45 8.78 5.9
156 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
157 INT47976 Protein_catabolism of NFKBIA 17 0.88 7.57 5.79
158 INT26555 Regulation of Positive_regulation of Oprd1 6 0.59 2.47 5.76
159 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
160 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
161 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
162 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
163 INT60585 Regulation of TP53 59 0.59 54.55 5.21
164 INT81535 Negative_regulation of Phosphorylation of Nfkbia 15 0.44 5.74 5.18
165 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
166 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
167 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
168 INT143234 Gene_expression of Nfkbia 10 0.62 5.2 5.02
169 INT105336 Regulation of AKT1 52 0.56 32.53 4.89
170 INT88496 Positive_regulation of Protein_catabolism of Nfkbia 8 0.53 3.05 4.78
171 INT62132 Regulation of Gene_expression of Ifng 12 0.62 1.28 4.77
172 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
173 INT131253 Positive_regulation of Gene_expression of Nfkbia 4 0.41 3.28 4.71
174 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
175 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
176 INT134657 Localization of Akt1 37 0.68 11.58 4.62
177 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
178 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
179 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
180 INT87210 Positive_regulation of Nfkbia 9 0.61 3.89 4.35
181 INT23738 Regulation of Transcription of Oprd1 6 0.26 0.48 4.3
182 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21
183 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
184 INT75136 Binding of Akt1 27 0.27 8.81 4.15
185 INT81543 Positive_regulation of Phosphorylation of Nfkbia 7 0.37 2.51 4.1
186 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
187 INT108868 Transcription of Nfkbia 2 0.57 2.91 4.03
188 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
189 INT108086 Negative_regulation of AKR1C3 17 0.58 7.7 3.99
190 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
191 INT29671 Regulation of Localization of Oprd1 4 0.24 1.04 3.92
192 INT65460 Positive_regulation of Gene_expression of Oprd1 8 0.69 1.87 3.87
193 INT71322 Positive_regulation of Binding of Oprd1 4 0.33 0.97 3.87
194 INT209018 Positive_regulation of Slc11a1 11 0.55 7.12 3.83
195 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
196 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79
197 INT34054 Regulation of Gene_expression of IFNG 8 0.42 3.69 3.76
198 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
199 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
200 INT136692 Localization of Akt1 12 0.78 2.14 3.65
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