GO:0000062

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Name fatty-acyl-CoA binding
Categary Function
Go Slim No
Go Link GO:0000062
Unique Molecular Interactions 115
Total Molecular Interactions 131
Total Single Events 1129
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for fatty-acyl-CoA binding. They are ordered first by their pain relevance and then by number of times they were reported for fatty-acyl-CoA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT138961 Dbi Positive_regulation of Chkb 1 0.00 3.05 3.99
2 INT138959 Dbi Positive_regulation of Penk 1 0.01 3.05 3.99
3 INT140011 Avp Positive_regulation of Dbi 2 0.07 0.93 3.61
4 INT138962 Dbi Positive_regulation of Pomc 1 0.00 1.53 2
5 INT138960 Dbi Positive_regulation of Avp 1 0.02 1.53 2
6 INT138958 Dbi Positive_regulation of Positive_regulation of Avp 1 0.02 1.53 2
7 INT140013 Avp Positive_regulation of Gene_expression of Dbi 1 0.07 0.85 1.52
8 INT140012 Avp Negative_regulation of Dbi 1 0.06 0.8 1.44
9 INT145407 Oprd1 Regulation of Positive_regulation of Dbi 1 0.17 0 1.07
10 INT145408 H2-Ab1 Negative_regulation of Gene_expression of Dbi 1 0.05 0 1.06
11 INT41093 Binding of Dbi and Nil 1 0.00 0 0.93
12 INT55204 Prl Positive_regulation of Localization of Dbi 1 0.02 0 0.91
13 INT87646 Dbi Regulation of Olfr1507 1 0.00 0.69 0.72
14 INT123077 Cacna1c Negative_regulation of Gene_expression of Dbi 1 0.05 0.71 0.7
15 INT82311 Binding of HADHA and Gast 1 0.03 0.37 0.68
16 INT82312 Negative_regulation of Binding of HADHA and Gast 1 0.04 0.37 0.68
17 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64
18 INT278688 MTX1 Negative_regulation of Positive_regulation of SOAT1 1 0.04 0.69 0.54
19 INT32479 Gh1 Negative_regulation of Dbi 1 0.01 0 0.51
20 INT220741 Binding of EGFR and SOAT1 1 0.02 0.37 0.49
21 INT34982 Trh Regulation of Dbi 1 0.12 0 0.47
22 INT34984 Negative_regulation of Trh Regulation of Dbi 1 0.19 0 0.47
23 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42
24 INT34983 Gene_expression of Dbi Positive_regulation of Localization of Trh 1 0.22 0 0.42
25 INT34981 Gene_expression of Dbi Positive_regulation of Localization of Prl 1 0.23 0 0.41
26 INT234608 Socs3 Negative_regulation of SOAT1 1 0.01 0.54 0.39
27 INT237369 SOAT1 Negative_regulation of Phosphorylation of JAK1 1 0.00 0 0.38
28 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35
29 INT164371 Dbi Regulation of Pomc 1 0.19 0.17 0.35
30 INT272755 Binding of DBI and Ptger2 1 0.00 1.13 0.33
31 INT260433 Dbi Positive_regulation of Cd8a 1 0.00 0.13 0.3
32 INT303949 LEPR Positive_regulation of SOAT1 1 0.01 0.22 0.28
33 INT82194 Dbi Regulation of Oprd1 1 0.12 0.07 0.26
34 INT43532 Dbi Negative_regulation of Localization of LH 1 0.15 0.75 0.23
35 INT35472 Dbi Regulation of Gnrh1 1 0.06 0.17 0.22
36 INT35468 Dbi Regulation of Prl 1 0.05 0.17 0.22
37 INT303606 Binding of IL18 and SOAT1 1 0.05 0.52 0.22
38 INT32326 Regulation of DBI Positive_regulation of GH1 1 0.02 0 0.21
39 INT32325 DBI Positive_regulation of GHRH 1 0.02 0 0.21
40 INT32328 DBI Positive_regulation of GH1 1 0.03 0 0.21
41 INT32331 DBI Positive_regulation of Localization of GHRH 1 0.02 0 0.21
42 INT35471 Dbi Negative_regulation of Localization of Gnrh1 1 0.05 0.14 0.19
43 INT32360 DBI Positive_regulation of Localization of PLOD1 1 0.05 0 0.19
44 INT26158 Binding of DBI and POMC 1 0.35 0.16 0.19
45 INT348059 Dbi Negative_regulation of Binding of Mpo 1 0.08 0.43 0.19
46 INT308518 HSP90B1 Positive_regulation of Positive_regulation of SOAT1 1 0.00 0.65 0.18
47 INT94355 NOVA2 Positive_regulation of Dbi 1 0.00 0.15 0.18
48 INT34346 CRH Regulation of DBI 1 0.01 0.25 0.17
49 INT42521 Pomc Regulation of Dbi 1 0.06 0 0.17
50 INT34351 Crh Regulation of DBI 1 0.00 0.25 0.17
51 INT32665 Pomc Negative_regulation of Dbi 1 0.06 0 0.17
52 INT34345 POMC Regulation of DBI 1 0.00 0.25 0.17
53 INT5520 Negative_regulation of Dbi Negative_regulation of Gene_expression of Crh 1 0.21 0.44 0.16
54 INT5517 Negative_regulation of Dbi Negative_regulation of Crh 1 0.27 0.44 0.16
55 INT355410 Ins1 Regulation of Gene_expression of Dbi 1 0.07 0.57 0.16
56 INT254497 GOPC Regulation of Transcription of HNF4A 1 0.02 0.72 0.16
57 INT186380 Binding of SOAT1 and Stat6 1 0.02 0.11 0.15
58 INT32359 POMC Positive_regulation of DBI 1 0.05 0 0.14
59 INT332256 Pdgfa Positive_regulation of SOAT1 1 0.01 0.51 0.14
60 INT323877 LEP Positive_regulation of SOAT1 1 0.20 1.26 0.14
61 INT355408 Ins1 Regulation of Dbi 1 0.07 0.58 0.14
62 INT262618 Binding of SOAT1 and Kras 1 0.00 0.81 0.12
63 INT43530 Dbi Negative_regulation of LH 1 0.18 0.3 0.1
64 INT323879 LEP Regulation of SOAT1 1 0.15 1.15 0.1
65 INT5519 Dbi Negative_regulation of Crh 1 0.31 0.28 0.1
66 INT43529 Dbi Negative_regulation of Gene_expression of LH 1 0.13 0.3 0.1
67 INT194742 SOAT1 Positive_regulation of Positive_regulation of IK 1 0.00 0.1 0.09
68 INT355021 Cntf Positive_regulation of SOAT1 1 0.02 0.7 0.08
69 INT254496 Binding of HNF4A and GOPC 1 0.10 0.34 0.08
70 INT94353 Crh Negative_regulation of Positive_regulation of Dbi 1 0.03 0.14 0.08
71 INT94354 Crh Negative_regulation of Dbi 1 0.03 0.14 0.08
72 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08
73 INT43528 Dbi Regulation of Localization of LH 1 0.09 0.21 0.07
74 INT301632 Binding of Dbi and Fabp1 1 0.13 0.49 0.07
75 INT212440 STAT3 Regulation of Phosphorylation of SOAT1 1 0.11 1.42 0.05
76 INT266078 VEGFA Positive_regulation of DBI 1 0.10 0.45 0.04
77 INT301643 Binding of Dbi and fa 1 0.05 0.45 0.03
78 INT280601 Binding of HIVEP1 and Dbi 1 0.00 1.57 0.03
79 INT287892 PRDX2 Positive_regulation of HNF4A 1 0.00 0.52 0
80 INT219416 CCNA2 Regulation of HNF4A 1 0.00 0.11 0
81 INT235596 HNF4A Regulation of Gene_expression of TPI1 1 0.00 0.25 0
82 INT36328 Binding of AMPD1 and Hmgcl 1 0.01 1.02 0
83 INT182952 KCNIP3 Positive_regulation of HNF4A 1 0.02 0.45 0
84 INT287882 Binding of CREBBP and HNF4A 1 0.01 0.85 0
85 INT182922 FRA8E Positive_regulation of HNF4A 1 0.00 0.2 0
86 INT301657 Binding of Dbi and Ppara 1 0.26 0.23 0
87 INT307214 Hnf4a Regulation of Ppara 1 0.18 0.35 0
88 INT182926 VDR Positive_regulation of HNF4A 1 0.02 0.09 0
89 INT326836 Binding of HNF4A and PLD2 1 0.03 0.35 0
90 INT253588 Csnk2a2 Regulation of Gene_expression of SOAT1 1 0.03 0 0
91 INT219410 CCNF Regulation of HNF4A 1 0.01 0.11 0
92 INT182938 Binding of HNF4A and KCNIP3 1 0.01 0.2 0
93 INT219426 CDK2 Regulation of HNF4A 1 0.01 0.11 0
94 INT262746 Binding of Dbi and RN7SL2 1 0.00 0 0
95 INT219420 CCNE2 Regulation of HNF4A 1 0.00 0.11 0
96 INT173123 Binding of HNF4A and PPARA 1 0.10 0.19 0
97 INT301650 Ins1 Positive_regulation of Dbi 1 0.02 0.23 0
98 INT183018 Dre Positive_regulation of HNF4A 1 0.00 0.09 0
99 INT182957 CDKN1A Negative_regulation of HNF4A 1 0.02 0.11 0
100 INT182927 Binding of HNF4A and HRES1 1 0.00 0 0
101 INT326902 Binding of HNF4A and Tcf4 1 0.02 0.35 0
102 INT169485 Dbi Regulation of Prkca 1 0.02 0.08 0
103 INT35470 Binding of Prl and Dbi 1 0.05 0.17 0
104 INT169484 Dbi Regulation of Oprk1 1 0.01 0.07 0
105 INT285042 Dbi Regulation of Gene_expression of Rho 1 0.01 0 0
106 INT262747 Binding of CHN1 and Dbi 1 0.01 0 0
107 INT343156 Binding of TSPO and DBI 1 0.04 0.63 0
108 INT183740 Dbi Negative_regulation of A230066D03Rik 1 0.00 0.69 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for fatty-acyl-CoA binding. They are ordered first by their pain relevance and then by number of times they were reported in fatty-acyl-CoA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2
2 INT5989 Positive_regulation of Dbi 79 0.49 24.38 32.56
3 INT5988 Localization of Dbi 74 0.81 17.52 24.09
4 INT78675 Gene_expression of Dbi 31 0.78 12.93 23.64
5 INT78670 Positive_regulation of Gene_expression of Dbi 26 0.70 6.72 19
6 INT11762 Regulation of Dbi 40 0.62 7.83 14.48
7 INT5512 Negative_regulation of Dbi 32 0.36 7.33 9.1
8 INT39457 Positive_regulation of SOAT1 32 0.67 22.8 8.28
9 INT30638 Positive_regulation of Gene_expression of Dbi 17 0.69 4.63 8.28
10 INT78678 Positive_regulation of Dbi 12 0.70 2.13 7.71
11 INT20343 Positive_regulation of Localization of Dbi 21 0.63 5.01 6.61
12 INT10675 Gene_expression of DBI 28 0.67 19.74 6.07
13 INT19779 Binding of Dbi 41 0.36 8.8 5.87
14 INT186063 Phosphorylation of SOAT1 29 0.28 11.77 5.34
15 INT78671 Transcription of Dbi 7 0.72 0.77 4.83
16 INT78672 Negative_regulation of Gene_expression of Dbi 6 0.43 0.67 4.75
17 INT27642 Regulation of Gene_expression of Dbi 10 0.44 2.55 3.66
18 INT10676 Negative_regulation of DBI 10 0.37 7 3.65
19 INT20344 Regulation of Localization of Dbi 8 0.49 1.97 3.31
20 INT94031 Regulation of Gene_expression of Dbi 4 0.24 3.36 3.08
21 INT8657 Binding of DBI 12 0.42 2.22 3.04
22 INT22402 Positive_regulation of DBI 17 0.59 7.77 2.91
23 INT60750 Gene_expression of HNF4A 12 0.65 8.29 2.68
24 INT78677 Regulation of Transcription of Dbi 1 0.62 0 2.48
25 INT91554 Positive_regulation of Transcription of Dbi 3 0.50 0.77 2.36
26 INT231557 Positive_regulation of Phosphorylation of SOAT1 7 0.22 5.22 2.33
27 INT22404 Regulation of DBI 7 0.39 3.66 2.24
28 INT82310 Binding of HADHA 1 0.39 1.16 2.05
29 INT145401 Positive_regulation of Positive_regulation of Dbi 1 0.44 0 2.03
30 INT91553 Regulation of Positive_regulation of Dbi 1 0.44 0 2
31 INT78960 Binding of SOAT1 9 0.36 2.56 1.92
32 INT39458 Negative_regulation of SOAT1 8 0.57 10.56 1.83
33 INT78676 Binding of Dbi 3 0.37 2.82 1.8
34 INT25499 Localization of DBI 14 0.52 5.31 1.7
35 INT32543 Negative_regulation of Gene_expression of Dbi 6 0.42 2.46 1.67
36 INT39459 Gene_expression of SOAT1 10 0.75 7.62 1.52
37 INT100540 Localization of SOAT1 9 0.78 2.67 1.42
38 INT155845 Transcription of SOAT1 6 0.67 2.89 1.4
39 INT82309 Positive_regulation of Binding of HADHA 1 0.35 0.87 1.38
40 INT94825 Regulation of Dbi 3 0.45 1.73 1.37
41 INT172630 Binding of HNF4A 16 0.05 7.78 1.22
42 INT60291 Regulation of SOAT1 9 0.19 3.99 1.17
43 INT32541 Positive_regulation of Positive_regulation of Dbi 2 0.39 0.5 1.14
44 INT123554 Transcription of Dbi 5 0.72 1.13 1.13
45 INT172616 Regulation of HNF4A 9 0.06 4.25 1.02
46 INT30942 Regulation of Regulation of Dbi 2 0.07 0.12 0.98
47 INT82308 Negative_regulation of HADHA 2 0.38 1.52 0.91
48 INT78674 Positive_regulation of Binding of Dbi 2 0.50 1 0.83
49 INT338858 Regulation of HADHA 1 0.03 0.61 0.72
50 INT338863 Positive_regulation of HADHA 1 0.03 0.61 0.72
51 INT30154 Positive_regulation of Localization of DBI 3 0.33 2.18 0.7
52 INT10677 Positive_regulation of Gene_expression of DBI 3 0.24 6.2 0.64
53 INT5504 Negative_regulation of Negative_regulation of Dbi 2 0.25 0.43 0.63
54 INT32542 Negative_regulation of Positive_regulation of Dbi 2 0.17 0 0.63
55 INT302813 Positive_regulation of Positive_regulation of SOAT1 3 0.22 4.2 0.58
56 INT21882 Negative_regulation of Localization of Dbi 3 0.45 0.28 0.55
57 INT264133 Protein_catabolism of SOAT1 1 0.05 0.38 0.55
58 INT26160 Negative_regulation of Binding of DBI 1 0.38 0.29 0.49
59 INT98945 Negative_regulation of Positive_regulation of SOAT1 1 0.41 0.65 0.46
60 INT275642 Negative_regulation of HNF4A 4 0.05 2.08 0.44
61 INT249596 Positive_regulation of Gene_expression of SOAT1 2 0.09 1.1 0.42
62 INT291958 Negative_regulation of Phosphorylation of SOAT1 2 0.05 0.58 0.39
63 INT42288 Negative_regulation of Binding of Dbi 1 0.13 0 0.37
64 INT317741 Positive_regulation of Transcription of SOAT1 2 0.49 0.62 0.35
65 INT106253 Positive_regulation of HNF4A 14 0.29 3.88 0.34
66 INT40307 Positive_regulation of Regulation of DBI 1 0.18 0 0.34
67 INT183208 Transcription of HNF4A 7 0.11 3.15 0.28
68 INT323896 Regulation of Phosphorylation of SOAT1 2 0.14 1.25 0.21
69 INT275639 Positive_regulation of Binding of HNF4A 2 0.04 0.87 0.21
70 INT32332 Negative_regulation of Localization of DBI 1 0.05 0 0.21
71 INT60751 Positive_regulation of Gene_expression of HNF4A 2 0.49 3.5 0.19
72 INT36325 Negative_regulation of Hmgcl 2 0.05 0.73 0.18
73 INT19780 Protein_catabolism of Dbi 3 0.29 0.43 0.17
74 INT164022 Regulation of Gene_expression of HNF4A 1 0.03 0.82 0.16
75 INT287917 Phosphorylation of HNF4A 1 0.08 0.07 0.13
76 INT266086 Negative_regulation of Gene_expression of DBI 1 0.07 1.16 0.1
77 INT126667 Localization of HNF4A 2 0.06 0.45 0.08
78 INT266090 Transcription of DBI 1 0.12 1.18 0.08
79 INT266087 Positive_regulation of Positive_regulation of DBI 1 0.09 1.35 0.06
80 INT287925 Regulation of Binding of HNF4A 1 0.06 1.1 0.05
81 INT266085 Negative_regulation of Positive_regulation of DBI 1 0.07 1.09 0.03
82 INT123553 Positive_regulation of Transcription of Dbi 2 0.69 0.52 0
83 INT253561 Regulation of Gene_expression of SOAT1 1 0.04 0 0
84 INT19781 Negative_regulation of Protein_catabolism of Dbi 1 0.18 0 0
85 INT326868 Positive_regulation of Transcription of HNF4A 1 0.04 0.08 0
86 INT300106 Negative_regulation of Gene_expression of SOAT1 1 0.06 0.8 0
87 INT301546 Negative_regulation of Dbi 1 0.31 0.23 0
88 INT326878 Negative_regulation of Gene_expression of HNF4A 1 0.03 0.43 0
89 INT249595 Positive_regulation of Binding of SOAT1 1 0.03 0.3 0
90 INT287915 Positive_regulation of Positive_regulation of HNF4A 1 0.06 0.37 0
91 INT280597 Positive_regulation of Negative_regulation of Dbi 1 0.03 0 0
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