GO:0000080

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Name G1 phase of mitotic cell cycle
Categary Process
Go Slim No
Go Link GO:0000080
Unique Molecular Interactions 244
Total Molecular Interactions 340
Total Single Events 2274
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for G1 phase of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for G1 phase of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
2 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
3 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
4 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
5 INT306823 Binding of E2F4 and GOPC 1 0.06 0.23 0.91
6 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
7 INT116107 CDK4 Positive_regulation of Phosphorylation of EID1 1 0.01 0.32 0.86
8 INT306831 Positive_regulation of Binding of E2F4 and NOLC1 1 0.10 0.46 0.85
9 INT306826 Binding of E2F4 and NOLC1 1 0.08 0.41 0.84
10 INT330101 Binding of Map3k11 and Rac1 1 0.16 2.43 0.62
11 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
12 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
13 INT166395 CDKN1A Regulation of Gene_expression of IFI27 1 0.32 0.83 0.61
14 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
15 INT166392 IFI27 Regulation of Gene_expression of CDKN1A 1 0.32 0.83 0.61
16 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
17 INT164262 TGM7 Negative_regulation of E2F1 1 0.16 1.08 0.53
18 INT306828 Binding of E2F2 and E2F3 1 0.20 0.15 0.46
19 INT306824 Binding of E2F1 and E2F2 1 0.15 0.15 0.46
20 INT158032 Binding of CDKN2A and KRT20 1 0.28 0.59 0.4
21 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
22 INT306830 E2F2 Regulation of C1orf61 1 0.02 0.48 0.36
23 INT306822 Binding of E2F2 and GOPC 1 0.05 0.53 0.35
24 INT204071 HP Positive_regulation of Gene_expression of CDKN2A 1 0.00 3.48 0.34
25 INT119262 PPM1E Negative_regulation of Positive_regulation of CDKN1A 1 0.01 0.96 0.33
26 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
27 INT166391 IFI27 Regulation of Gene_expression of CDKN1B 1 0.33 0.41 0.31
28 INT166397 CDKN1B Regulation of Gene_expression of IFI27 1 0.33 0.41 0.31
29 INT330100 Binding of Sh3rf1 and Map3k11 1 0.08 1.21 0.31
30 INT147593 Binding of CDK4 and CDKN2A 1 0.42 0.23 0.26
31 INT147592 Positive_regulation of Binding of CDK4 and CDKN2A 1 0.44 0.23 0.26
32 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
33 INT264517 PTGDS Positive_regulation of TFDP1 1 0.17 0.5 0.22
34 INT264519 PTGDS Negative_regulation of Positive_regulation of TFDP1 1 0.15 0.5 0.22
35 INT212084 NOXO1 Positive_regulation of CDKN1A 1 0.06 0.53 0.19
36 INT119264 Binding of RB1 and PPM1E 1 0.00 0.46 0.17
37 INT119263 Binding of CDKN1A and PPM1E 1 0.01 0.46 0.17
38 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14
39 INT123192 Bmp6 Positive_regulation of CDKN1A 1 0.18 0.61 0.14
40 INT223538 Binding of HAND1 and Tcf3 1 0.39 1.13 0.14
41 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14
42 INT193789 SDF2L1 Positive_regulation of CDKN1A 1 0.00 0.68 0.13
43 INT193785 SDF2L1 Positive_regulation of Gene_expression of CDKN1A 1 0.00 0.68 0.13
44 INT302156 AKT1 Positive_regulation of E2F2 1 0.02 0.88 0.13
45 INT223530 Binding of Tcf3 and Szf1 1 0.33 0.92 0.13
46 INT223526 Binding of Pax6 and Tcf3 1 0.33 0.92 0.13
47 INT298267 Tcf3 Positive_regulation of Gene_expression of Runx1 1 0.21 0.6 0.1
48 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
49 INT233858 CHKA Positive_regulation of Gene_expression of CDKN1B 1 0.10 0.17 0.09
50 INT185279 Binding of CCND1 and CDK4 4 0.13 2.05 0.08
51 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08
52 INT238392 RB1 Regulation of E2F2 1 0.01 0.36 0.08
53 INT237922 TNFSF10 Positive_regulation of CDKN1A 1 0.09 3.28 0.08
54 INT302178 CDKN1C Regulation of CDKN2A 1 0.09 0.26 0.08
55 INT238397 EID1 Regulation of E2F2 1 0.00 0.36 0.08
56 INT302158 CDKN1A Regulation of CDKN2A 1 0.04 0.26 0.08
57 INT302139 LAMTOR1 Regulation of CDKN2A 1 0.08 0.26 0.08
58 INT302157 MRPL28 Regulation of CDKN2A 1 0.09 0.26 0.08
59 INT245118 RBM45 Negative_regulation of CDKN2B 1 0.01 1.41 0.08
60 INT302148 IFI27 Regulation of CDKN2A 1 0.11 0.26 0.08
61 INT245119 Negative_regulation of RBM45 Negative_regulation of CDKN2B 1 0.01 1.43 0.08
62 INT297964 Binding of CDK8 and MAP3K11 1 0.26 0.29 0.07
63 INT297969 Positive_regulation of Binding of CDK8 and MAP3K11 1 0.35 0.29 0.07
64 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07
65 INT223531 Binding of Hmga1 and Tcf3 1 0.26 0.57 0.07
66 INT193783 ITIH4 Regulation of Gene_expression of CDKN1A 1 0.03 0.55 0.07
67 INT119268 CDKN1A Regulation of CREBBP 1 0.21 0.44 0.07
68 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07
69 INT302160 LAMTOR1 Regulation of CDKN1A 1 0.08 0.26 0.06
70 INT302150 MRPL28 Regulation of CDKN1B 1 0.09 0.26 0.06
71 INT302136 LAMTOR1 Regulation of CDKN1B 1 0.08 0.26 0.06
72 INT302127 MRPL28 Regulation of CDKN1A 1 0.09 0.26 0.06
73 INT302133 IFI27 Regulation of CDKN1B 1 0.11 0.26 0.05
74 INT302130 CDKN1A Regulation of CDKN1B 1 0.04 0.26 0.05
75 INT302176 CDKN1C Regulation of CDKN1A 1 0.09 0.26 0.05
76 INT302141 CDKN1C Regulation of CDKN1B 1 0.09 0.26 0.05
77 INT204072 Binding of Cdkn2a and Cdk6 1 0.02 0.78 0.05
78 INT302163 IFI27 Regulation of CDKN1A 1 0.11 0.26 0.05
79 INT287221 Tcf3 Regulation of Transcription of Insig1 1 0.03 0.56 0.05
80 INT292815 Binding of CDC123 and FTO 1 0.50 0.48 0.05
81 INT207702 CCND1 Regulation of MSMB 1 0.22 0.69 0.04
82 INT176224 Binding of CDKN1A and PCNA 4 0.08 2.52 0.03
83 INT302159 TSC1 Positive_regulation of Transcription of CDKN1A 1 0.00 0.28 0.03
84 INT303091 Rorb Regulation of CDKN1A 1 0.00 0.52 0.03
85 INT283722 Id2 Negative_regulation of Transcription of CDKN1A 1 0.45 0.11 0.03
86 INT238395 BAX Regulation of CDKN1A 1 0.03 0.31 0.03
87 INT94157 CDCP1 Negative_regulation of RB1 1 0.02 0.92 0.03
88 INT314677 TP53 Regulation of Positive_regulation of CDKN2A 1 0.27 0.97 0.03
89 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03
90 INT94159 Positive_regulation of CDK1 Negative_regulation of RB1 1 0.45 0.93 0.03
91 INT223067 IFI27 Negative_regulation of CCND1 1 0.05 0.65 0.03
92 INT94158 CDK1 Negative_regulation of RB1 1 0.41 0.92 0.03
93 INT223066 CDKN1A Negative_regulation of CCND1 1 0.04 0.66 0.03
94 INT238393 Binding of E2F2 and RB1 3 0.04 0.24 0
95 INT144030 STAT3 Regulation of CCND1 2 0.09 1.05 0
96 INT201771 CDKN1A Positive_regulation of Localization of Ccnd1 1 0.04 0 0
97 INT325154 CDKN1B Negative_regulation of CCNE2 1 0.07 0.1 0
98 INT182942 VDR Positive_regulation of CDKN1A 1 0.35 0.38 0
99 INT329680 BMI1 Negative_regulation of Gene_expression of CDKN2A 1 0.15 1.14 0
100 INT215766 Dio1 Regulation of Cdk6 1 0.01 0.05 0
101 INT329676 CBX7 Regulation of Localization of CDKN2A 1 0.51 2.4 0
102 INT318081 Binding of RPL5 and UBC 1 0.02 0.52 0
103 INT238402 ELANE Positive_regulation of Gene_expression of CDKN1A 1 0.03 0.48 0
104 INT337402 LEF1 Positive_regulation of E2F1 1 0.11 0 0
105 INT219409 CCNF Regulation of E2F2 1 0.22 0.11 0
106 INT246914 Binding of CDKN2A and Ifng 1 0.01 0.71 0
107 INT306827 Binding of E2F2 and NOLC1 1 0.07 0.05 0
108 INT225157 CDKN1A Regulation of CHKA 1 0.12 0.58 0
109 INT268316 Cdk1 Positive_regulation of Mcm3 1 0.28 0.25 0
110 INT337270 E2F1 Positive_regulation of Transcription of THBS1 1 0.67 0.19 0
111 INT334322 Binding of RB1 and TP53 1 0.34 2 0
112 INT337268 E2F1 Regulation of Transcription of THBS1 1 0.44 0 0
113 INT298197 EGFR Regulation of CDKN1A 1 0.04 1.14 0
114 INT325156 CDKN1B Negative_regulation of CDK2 1 0.49 0.11 0
115 INT311404 Binding of CDKN2A and Celf1 1 0.32 0.07 0
116 INT182402 E2F2 Regulation of CCNB1 1 0.00 0.09 0
117 INT337274 E2F1 Regulation of THBS1 1 0.44 0 0
118 INT337269 Binding of E2F1 and Positive_regulation of Gene_expression of THBS1 1 0.45 0.21 0
119 INT273774 Binding of GPER and RB1 1 0.01 0.45 0
120 INT214892 Positive_regulation of HGF Positive_regulation of CDKN1A 1 0.17 0.31 0
121 INT185281 Binding of CDK6 and CDKN2A 1 0.29 0.87 0
122 INT215706 Binding of Cdk6 and Lamtor1 1 0.04 0 0
123 INT225645 Binding of TAF1 and Acp5 1 0.01 0 0
124 INT176292 Fasl Regulation of Gene_expression of CDKN1A 1 0.34 0.84 0
125 INT204234 Binding of CDKN2A and TP53 1 0.43 1.27 0
126 INT224291 Negative_regulation of ESR1 Positive_regulation of CCND1 1 0.16 0.07 0
127 INT214918 Gtf3a Positive_regulation of CDKN1A 1 0.01 0.66 0
128 INT250658 FOS Positive_regulation of CCND1 1 0.03 0.6 0
129 INT306825 Positive_regulation of Binding of E2F2 and RB1 1 0.04 0.05 0
130 INT145338 Binding of PYGO1 and Positive_regulation of Transcription of CCND1 1 0.07 0 0
131 INT318103 Binding of UBC and Hprt 1 0.10 0.52 0
132 INT215700 Binding of Cdkn2b and Cdk6 1 0.02 0 0
133 INT182399 E2F2 Regulation of CDK1 1 0.00 0.09 0
134 INT215690 Binding of Cdk6 and Cdkn1c 1 0.03 0 0
135 INT337264 Binding of E2F1 and THBS1 1 0.47 0.78 0
136 INT333448 RB1 Positive_regulation of TFDP1 1 0.05 0 0
137 INT268318 Cdk1 Positive_regulation of Orc2 1 0.29 0.25 0
138 INT219425 CCNA2 Regulation of SKP2 1 0.11 0.11 0
139 INT330696 Phosphorylation of RB1 Positive_regulation of Gene_expression of E2F2 1 0.01 1 0
140 INT182912 Binding of CDKN1A and FRA8E 1 0.02 0.37 0
141 INT337273 E2F1 Regulation of Gene_expression of THBS1 1 0.60 0 0
142 INT338197 CCND1 Negative_regulation of AR 1 0.24 0 0
143 INT214890 GOPC Positive_regulation of CDKN1A 1 0.06 0.57 0
144 INT325152 CDKN1A Negative_regulation of CCNE2 1 0.07 0.1 0
145 INT219411 CCNF Regulation of SKP2 1 0.22 0.11 0
146 INT217149 MIR20A Regulation of Gene_expression of E2F1 1 0.19 0.86 0
147 INT330698 PCNA Regulation of RB1 1 0.00 0.3 0
148 INT302154 STAT3 Regulation of Transcription of CCND1 1 0.04 0.99 0
149 INT276379 Binding of SKP2 and Cdkn1b 1 0.02 0.57 0
150 INT185280 Binding of CDK4 and CDK6 1 0.20 0.87 0
151 INT184956 ID1 Negative_regulation of CDKN2A 1 0.42 0.21 0
152 INT214891 HGF Positive_regulation of CDKN1A 1 0.25 1.15 0
153 INT182935 KCNIP3 Regulation of CDKN1A 1 0.45 0.96 0
154 INT337266 E2F1 Positive_regulation of Gene_expression of THBS1 1 0.67 0.21 0
155 INT204078 Binding of CDKN2A and Cdk4 1 0.15 0.72 0
156 INT215682 Binding of Cdkn1b and Cdk6 1 0.03 0 0
157 INT337491 Binding of E2F1 and Tcf7 1 0.19 0 0
158 INT276303 Negative_regulation of AKT1 Negative_regulation of CCND1 1 0.01 0.58 0
159 INT268319 Cdk1 Positive_regulation of Cdc20 1 0.32 0.25 0
160 INT337401 Binding of E2F1 and HDAC1 1 0.07 0 0
161 INT337261 Binding of E2F1 and PRB1 1 0.17 1.19 0
162 INT214919 Pkd1 Positive_regulation of CDKN1A 1 0.51 2.6 0
163 INT215701 Slc3a1 Regulation of Cdk6 1 0.01 0.05 0
164 INT217771 MIR181A1 Regulation of E2F5 1 0.19 0.7 0
165 INT208152 Binding of CDK4 and MDM2 1 0.01 1.11 0
166 INT219413 CDK2 Regulation of SKP2 1 0.23 0.11 0
167 INT268317 Cdk1 Positive_regulation of Mcm7 1 0.33 0.25 0
168 INT354115 MIR222 Regulation of Gene_expression of CDKN1B 1 0.07 0.98 0
169 INT329677 CDKN2A Regulation of CBX7 1 0.31 2.23 0
170 INT337265 Negative_regulation of E2F1 Positive_regulation of THBS1 1 0.42 0 0
171 INT219427 CCNE2 Regulation of E2F2 1 0.11 0.11 0
172 INT219408 CCNA2 Regulation of E2F2 1 0.11 0.11 0
173 INT285878 Negative_regulation of Binding of CCND1 and CDK4 1 0.00 0.44 0
174 INT182957 CDKN1A Negative_regulation of HNF4A 1 0.02 0.11 0
175 INT306829 Binding of E2F2 and RBL1 1 0.09 0.06 0
176 INT247427 CDKN2A Negative_regulation of Negative_regulation of RB1 1 0.07 1.16 0
177 INT337272 E2F1 Positive_regulation of THBS1 1 0.49 1.27 0
178 INT337267 THBS1 Positive_regulation of E2F1 1 0.49 0.05 0
179 INT214917 Pkd1 Positive_regulation of Negative_regulation of CDKN1A 1 0.37 1.46 0
180 INT186051 IFI27 Regulation of Gene_expression of CCND1 1 0.30 0.66 0
181 INT204077 Binding of CDKN2A and Cdk6 1 0.15 0.72 0
182 INT238401 PPARA Positive_regulation of Gene_expression of CDKN1A 1 0.11 0.48 0
183 INT182400 E2F2 Regulation of CDC25C 1 0.00 0.09 0
184 INT284915 Binding of CDKN2B and HIST2H3C 1 0.05 0.43 0
185 INT175194 Binding of UBC and NUP62 1 0.01 0.05 0
186 INT276302 Binding of SKP2 and CIB1 1 0.03 0.57 0
187 INT182917 Binding of VDR and Positive_regulation of Gene_expression of CDKN1A 1 0.35 0.31 0
188 INT217147 MIR17 Regulation of Gene_expression of E2F1 1 0.20 0.85 0
189 INT338972 Binding of CDKN1A and TP53 1 0.10 0.98 0
190 INT314685 TBX2 Negative_regulation of CDKN2A 1 0.32 1.16 0
191 INT305336 TP53 Negative_regulation of Phosphorylation of RB1 1 0.29 0.96 0
192 INT281608 Foxo4 Positive_regulation of Transcription of Trim63 1 0.27 0 0
193 INT201756 CDKN1B Positive_regulation of Localization of Ccnd1 1 0.04 0 0
194 INT329679 CBX7 Regulation of CDKN2A 1 0.31 4.18 0
195 INT268315 Cdk1 Positive_regulation of Mcm5 1 0.33 0.25 0
196 INT147144 E2F1 Positive_regulation of Transcription of TYMS 1 0.26 0 0
197 INT215703 Binding of Kras and Cdk6 1 0.01 0 0
198 INT314680 Positive_regulation of TBX2 Negative_regulation of CDKN2A 1 0.34 1.16 0
199 INT224290 ESR1 Positive_regulation of CCND1 1 0.17 0.07 0
200 INT182931 VDR Positive_regulation of Gene_expression of CDKN1A 1 0.48 0.86 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for G1 phase of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in G1 phase of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
2 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
3 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99
4 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61
5 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
6 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47
7 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93
8 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
9 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56
10 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38
11 INT99549 Gene_expression of CDKN1B 30 0.75 17 5.15
12 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
13 INT174189 Gene_expression of E2F2 19 0.49 12.58 4.71
14 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
15 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28
16 INT75500 Negative_regulation of Gene_expression of CCND1 21 0.57 11.59 3.24
17 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21
18 INT72618 Regulation of Tcf3 5 0.44 1.48 3.16
19 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07
20 INT75499 Positive_regulation of Positive_regulation of CDKN1A 12 0.60 7.28 2.84
21 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66
22 INT306835 Regulation of E2F2 1 0.39 2.52 2.62
23 INT99548 Positive_regulation of Gene_expression of CDKN1B 12 0.67 6.79 2.5
24 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48
25 INT338170 Regulation of Regulation of CDKN2A 1 0.44 0.96 2.46
26 INT175703 Negative_regulation of E2F2 6 0.38 3.47 2.44
27 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31
28 INT163283 Gene_expression of E2F1 21 0.71 3.77 2.26
29 INT306869 Gene_expression of E2F4 1 0.58 1.1 2.11
30 INT104402 Positive_regulation of CCND1 15 0.70 11.77 2.08
31 INT72616 Negative_regulation of Tcf3 2 0.41 0.97 2.04
32 INT99547 Positive_regulation of CDKN1B 18 0.67 8.42 1.96
33 INT104331 Negative_regulation of Gene_expression of CDKN1A 24 0.57 13.68 1.63
34 INT306853 Binding of E2F4 1 0.28 1.37 1.63
35 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57
36 INT116116 Phosphorylation of CDK4 3 0.56 2.18 1.56
37 INT182427 Binding of E2F2 7 0.23 2.78 1.49
38 INT78470 Negative_regulation of Gene_expression of CDKN2A 14 0.59 14.44 1.38
39 INT328202 Gene_expression of RBL1 1 0.13 1.84 1.37
40 INT160009 Transcription of CDKN1B 2 0.67 1.43 1.29
41 INT63905 Regulation of RB1 13 0.62 12.67 1.28
42 INT306868 Positive_regulation of Gene_expression of E2F1 6 0.46 1.01 1.28
43 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26
44 INT306857 Binding of E2F3 1 0.21 1.22 1.24
45 INT217827 Gene_expression of E2F5 2 0.46 2.3 1.21
46 INT72614 Negative_regulation of Regulation of Tcf3 1 0.41 0.17 1.2
47 INT239028 Negative_regulation of Foxo4 1 0.42 2.75 1.16
48 INT118368 Positive_regulation of E2F1 10 0.69 0.8 1.13
49 INT260285 Gene_expression of E2F3 6 0.54 2.51 1.13
50 INT126993 Binding of E2F1 5 0.44 1.39 1.12
51 INT328203 Positive_regulation of RBL1 1 0.12 2.62 1.12
52 INT160008 Positive_regulation of Transcription of CDKN1B 1 0.49 0.98 1.1
53 INT238440 Negative_regulation of Binding of E2F2 3 0.27 1.09 1.07
54 INT238433 Negative_regulation of Gene_expression of E2F2 2 0.27 1.01 1.07
55 INT147602 Negative_regulation of CDK4 8 0.35 4.6 1.04
56 INT160012 Regulation of Gene_expression of CDKN1B 2 0.44 1.17 1.04
57 INT250699 Binding of CDK6 3 0.33 2.54 0.97
58 INT174188 Positive_regulation of Gene_expression of RB1 9 0.45 6.22 0.94
59 INT306846 Negative_regulation of Binding of E2F3 1 0.24 0.65 0.94
60 INT306891 Negative_regulation of E2F3 1 0.25 0.65 0.94
61 INT338168 Positive_regulation of Binding of CDKN2A 1 0.49 0.52 0.94
62 INT163280 Negative_regulation of Phosphorylation of CCND1 6 0.19 3.92 0.87
63 INT306888 Positive_regulation of Binding of E2F4 1 0.37 0.58 0.87
64 INT306862 Regulation of Gene_expression of E2F2 1 0.17 0.19 0.85
65 INT306834 Positive_regulation of Gene_expression of E2F3 2 0.29 1 0.82
66 INT306840 Positive_regulation of Gene_expression of E2F4 1 0.37 0.58 0.82
67 INT306867 Positive_regulation of Gene_expression of E2F2 1 0.31 0.59 0.82
68 INT163289 Phosphorylation of CCND1 7 0.36 4.81 0.81
69 INT306889 Positive_regulation of Gene_expression of E2F5 1 0.30 0.58 0.81
70 INT146521 Negative_regulation of Positive_regulation of CDKN1A 6 0.42 3.29 0.79
71 INT126990 Positive_regulation of Binding of E2F1 4 0.58 0 0.79
72 INT30050 Gene_expression of Tcf3 13 0.48 2.57 0.77
73 INT306883 Negative_regulation of Phosphorylation of CDK4 1 0.17 1.06 0.71
74 INT201627 Gene_expression of Foxo4 3 0.65 1.92 0.63
75 INT106608 Regulation of Gene_expression of SKP2 1 0.50 0.26 0.63
76 INT106603 Gene_expression of SKP2 5 0.63 6.99 0.62
77 INT251026 Negative_regulation of Phosphorylation of CDKN2A 5 0.42 5.02 0.62
78 INT306884 Negative_regulation of E2F4 1 0.44 0.61 0.62
79 INT201640 Phosphorylation of Foxo4 4 0.80 3.55 0.61
80 INT306839 Negative_regulation of Gene_expression of E2F1 2 0.39 0.24 0.61
81 INT239019 Negative_regulation of Phosphorylation of Foxo4 2 0.42 2.38 0.61
82 INT105266 Localization of Tcf3 3 0.32 1.08 0.59
83 INT147598 Negative_regulation of Positive_regulation of CDKN2A 3 0.41 1.47 0.59
84 INT128498 Regulation of CCND1 17 0.39 12.51 0.58
85 INT120358 Positive_regulation of Positive_regulation of CDKN1B 2 0.49 1.26 0.55
86 INT118369 Regulation of E2F1 5 0.56 3.51 0.52
87 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51
88 INT75498 Positive_regulation of Gene_expression of CCND1 21 0.68 19.4 0.51
89 INT92328 Gene_expression of Map3k11 1 0.06 0.46 0.49
90 INT146522 Negative_regulation of Positive_regulation of CCND1 3 0.30 2.04 0.48
91 INT175702 Positive_regulation of E2F2 2 0.43 0.46 0.46
92 INT158643 Negative_regulation of Negative_regulation of CCND1 2 0.31 2.43 0.45
93 INT306885 Positive_regulation of SKP2 1 0.21 0.6 0.45
94 INT220088 Positive_regulation of Positive_regulation of CDKN2A 4 0.49 4.04 0.44
95 INT252657 Positive_regulation of Phosphorylation of CDKN2A 2 0.45 3.09 0.42
96 INT125592 Negative_regulation of Negative_regulation of CDKN1A 2 0.42 2.07 0.41
97 INT306864 Negative_regulation of Gene_expression of E2F4 1 0.32 0.28 0.41
98 INT194993 Binding of RB1 15 0.37 10.96 0.4
99 INT172626 Localization of E2F1 3 0.78 1.97 0.4
100 INT306859 Localization of E2F4 1 0.56 0.65 0.4
101 INT306872 Localization of E2F5 1 0.42 0.65 0.4
102 INT127451 Positive_regulation of Cdk1 1 0.20 0.27 0.4
103 INT128831 Binding of RBL1 2 0.31 0.27 0.39
104 INT147152 Negative_regulation of E2F1 6 0.56 0.89 0.38
105 INT203568 Regulation of SKP2 3 0.26 1.61 0.38
106 INT30052 Positive_regulation of Tcf3 3 0.41 0.27 0.37
107 INT328201 Localization of RBL1 1 0.12 1.01 0.34
108 INT129153 Phosphorylation of CDKN1B 2 0.61 1.41 0.33
109 INT82797 Transcription of CDKN1A 11 0.69 8.01 0.32
110 INT251025 Phosphorylation of CDKN2A 4 0.61 3.19 0.32
111 INT119269 Binding of CDKN1A 14 0.47 8.82 0.31
112 INT238429 Transcription of E2F2 3 0.45 0.55 0.31
113 INT330099 Binding of Map3k11 1 0.24 1.21 0.31
114 INT75504 Gene_expression of CDK4 9 0.72 7.43 0.3
115 INT123529 Phosphorylation of CDKN1A 8 0.80 5.69 0.29
116 INT126991 Regulation of Binding of E2F1 1 0.23 0 0.28
117 INT126992 Positive_regulation of Regulation of E2F1 1 0.58 0 0.28
118 INT203616 Positive_regulation of CDKN1C 2 0.60 12.62 0.27
119 INT186057 Binding of CCND1 8 0.31 5.92 0.26
120 INT264536 Gene_expression of TFDP1 1 0.19 0.56 0.26
121 INT341565 Negative_regulation of Positive_regulation of CDC123 1 0.20 0.15 0.26
122 INT184624 Localization of CDKN2A 8 0.74 7.87 0.25
123 INT185282 Localization of E2F2 3 0.47 1.92 0.25
124 INT238494 Regulation of Transcription of CDKN2A 1 0.16 5.62 0.25
125 INT225177 Regulation of Negative_regulation of CDKN1A 1 0.39 0.26 0.25
126 INT113989 Regulation of Gene_expression of CCND1 11 0.44 7.57 0.24
127 INT306879 Negative_regulation of Transcription of E2F2 1 0.37 0.07 0.24
128 INT248401 Gene_expression of CDKN1C 21 0.67 14.52 0.23
129 INT239796 Binding of TAF1 1 0.01 0.33 0.23
130 INT233869 Binding of CDKN1B 2 0.47 0.46 0.22
131 INT264535 Positive_regulation of TFDP1 1 0.16 0.39 0.22
132 INT179889 Negative_regulation of CDKN1B 4 0.57 1.71 0.21
133 INT306296 Regulation of CDKN1B 1 0.19 0.46 0.21
134 INT293677 Transcription of RB1 1 0.62 0.8 0.18
135 INT248400 Regulation of CDKN1C 1 0.45 2.92 0.17
136 INT257557 Negative_regulation of MAP3K11 3 0.30 2.38 0.16
137 INT201689 Protein_catabolism of CDKN1B 3 0.96 0.7 0.16
138 INT94168 Positive_regulation of Phosphorylation of RB1 12 0.60 6.6 0.15
139 INT147149 Transcription of CDKN2A 8 0.67 6.85 0.15
140 INT248403 Positive_regulation of Gene_expression of CDKN1C 1 0.40 7.77 0.14
141 INT123181 Positive_regulation of Negative_regulation of CDKN1A 1 0.49 0.6 0.14
142 INT233867 Negative_regulation of SKP2 3 0.24 2.25 0.13
143 INT197627 Localization of RB1 3 0.69 4.16 0.13
144 INT90229 Transcription of Tcf3 2 0.12 0.39 0.13
145 INT341549 Positive_regulation of CDC123 1 0.24 0.08 0.13
146 INT314724 Regulation of Localization of RB1 1 0.15 1.25 0.13
147 INT257732 Regulation of Positive_regulation of RB1 2 0.39 2.35 0.09
148 INT233868 Localization of CDKN1B 2 0.73 0.37 0.09
149 INT233872 Negative_regulation of Negative_regulation of SKP2 2 0.24 0.94 0.08
150 INT326819 Negative_regulation of Cdk1 1 0.16 0.39 0.08
151 INT233871 Negative_regulation of Protein_catabolism of CDKN1B 1 0.57 0.27 0.08
152 INT145375 Transcription of CCND1 7 0.52 3.86 0.07
153 INT185284 Binding of CDK4 7 0.25 4.79 0.07
154 INT245123 Gene_expression of CDKN2B 6 0.68 3.62 0.07
155 INT184989 Positive_regulation of CDKN2B 3 0.47 2.77 0.07
156 INT185030 Binding of CDKN2B 3 0.35 2.6 0.07
157 INT163282 Negative_regulation of Phosphorylation of E2F1 1 0.35 0.33 0.07
158 INT163288 Phosphorylation of E2F1 1 0.66 0.33 0.07
159 INT176262 Positive_regulation of Phosphorylation of CDKN1A 3 0.49 2.12 0.06
160 INT173191 Regulation of CDK4 1 0.26 0.39 0.06
161 INT176590 Positive_regulation of Transcription of CCND1 1 0.17 0.27 0.05
162 INT306881 Positive_regulation of Phosphorylation of RBL1 1 0.14 0.13 0.05
163 INT295091 Positive_regulation of Gene_expression of Tcf3 2 0.19 0.4 0.04
164 INT318095 Gene_expression of UBC 1 0.16 1.24 0.04
165 INT221830 Negative_regulation of Transcription of CCND1 3 0.18 2.15 0.03
166 INT224295 Protein_catabolism of CDKN1A 1 0.12 0.55 0.03
167 INT203619 Positive_regulation of Positive_regulation of CDKN1C 1 0.13 0.34 0.03
168 INT174197 Negative_regulation of Gene_expression of RB1 4 0.47 4.25 0
169 INT260292 Positive_regulation of E2F3 3 0.55 1.33 0
170 INT284972 Negative_regulation of CDKN2B 3 0.44 1.13 0
171 INT204060 Gene_expression of Cdk6 3 0.26 0.83 0
172 INT185289 Phosphorylation of E2F2 3 0.11 1.39 0
173 INT248399 Negative_regulation of CDKN1C 2 0.37 2.71 0
174 INT348463 Protein_catabolism of RB1 2 0.11 2.22 0
175 INT225170 Regulation of Phosphorylation of RB1 2 0.36 1.12 0
176 INT325167 Gene_expression of CDK6 2 0.43 0 0
177 INT225167 Negative_regulation of Binding of RB1 2 0.34 1.25 0
178 INT247431 Positive_regulation of Negative_regulation of RB1 2 0.45 2.58 0
179 INT271100 Regulation of Positive_regulation of CDKN1A 2 0.44 1.52 0
180 INT147151 Positive_regulation of Negative_regulation of CDKN2A 2 0.47 1.74 0
181 INT284937 Negative_regulation of Positive_regulation of CDKN2B 1 0.37 0.31 0
182 INT295084 Regulation of Gene_expression of Tcf3 1 0.20 0.36 0
183 INT185288 Negative_regulation of Localization of E2F2 1 0.07 1.02 0
184 INT201630 Positive_regulation of Phosphorylation of Foxo4 1 0.49 0.46 0
185 INT305634 Localization of CCND1 1 0.07 2.69 0
186 INT222135 Binding of Foxo4 1 0.02 0 0
187 INT292838 Gene_expression of TAF1 1 0.04 0.48 0
188 INT325178 Regulation of Positive_regulation of CDKN1B 1 0.44 0.05 0
189 INT325180 Negative_regulation of Gene_expression of CDKN1B 1 0.57 0.25 0
190 INT308400 Negative_regulation of Regulation of CDKN2A 1 0.40 0.87 0
191 INT217169 Positive_regulation of Transcription of E2F1 1 0.46 0.79 0
192 INT276362 Protein_catabolism of CCND1 1 0.10 0.66 0
193 INT172979 Regulation of Negative_regulation of CDKN2A 1 0.44 0.57 0
194 INT281254 Negative_regulation of Negative_regulation of CDKN2A 1 0.08 1.44 0
195 INT293681 Positive_regulation of Positive_regulation of RB1 1 0.39 0.27 0
196 INT258060 Positive_regulation of Protein_catabolism of E2F1 1 0.08 0.52 0
197 INT175213 Negative_regulation of Binding of UBC 1 0.02 0.13 0
198 INT147147 Positive_regulation of Transcription of CDKN2A 1 0.49 0 0
199 INT156902 Positive_regulation of UBC 1 0.49 0 0
200 INT297265 Positive_regulation of Positive_regulation of CCND1 1 0.07 0.94 0
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