GO:0000082

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Name G1/S transition of mitotic cell cycle
Categary Process
Go Slim No
Go Link GO:0000082
Unique Molecular Interactions 1099
Total Molecular Interactions 1531
Total Single Events 12407
Pain Genes Associated 89

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for G1/S transition of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for G1/S transition of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
2 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
3 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
4 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
5 INT73116 TYMS Negative_regulation of DNMT3B 1 0.24 0 1.6
6 INT73115 TYMS Negative_regulation of Positive_regulation of DNMT3B 1 0.24 0 1.6
7 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
8 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
9 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
10 INT136843 Binding of Camk2a and Nrgn 1 0.47 0 1.47
11 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
12 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
13 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
14 INT341218 Binding of Eif4e and Eif4ebp1 1 0.19 2.65 1.23
15 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14
16 INT317549 Negative_regulation of Camk2a Negative_regulation of Phosphorylation of Oprm1 1 0.19 0 1.14
17 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
18 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
19 INT157142 OPA1 Positive_regulation of Gene_expression of Camk2a 1 0.02 0.3 1.02
20 INT79602 Binding of PSMA5 and Oprd1 2 0.19 1.05 1.01
21 INT317544 Camk2a Regulation of Negative_regulation of Oprm1 1 0.20 0.07 1
22 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
23 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
24 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
25 INT142129 Nrgn Regulation of Camk2a 1 0.48 0.25 0.89
26 INT223867 Camk2a Positive_regulation of Positive_regulation of Ltp 1 0.25 0 0.87
27 INT116107 CDK4 Positive_regulation of Phosphorylation of EID1 1 0.01 0.32 0.86
28 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
29 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
30 INT86150 Inhba Positive_regulation of Gene_expression of Calca 1 0.09 0.61 0.81
31 INT150681 Pomc Positive_regulation of Camk2a 1 0.47 0.07 0.8
32 INT150679 Pomc Regulation of Gene_expression of Camk2a 1 0.30 0.07 0.79
33 INT144286 ACP1 Negative_regulation of Phosphorylation of PSMC6 1 0.45 0.39 0.78
34 INT147913 Phosphorylation of Camk2a Positive_regulation of Binding of Lpl 1 0.10 0 0.77
35 INT116803 Phosphorylation of Camk2b Positive_regulation of Camk4 1 0.03 0 0.76
36 INT116805 Phosphorylation of Camk2b Positive_regulation of Camk2a 1 0.07 0 0.76
37 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
38 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
39 INT71595 Camk2a Regulation of Negative_regulation of Oprm1 1 0.04 0 0.69
40 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66
41 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
42 INT112870 Aap Positive_regulation of Gene_expression of Ccnd1 1 0.24 0.34 0.63
43 INT186429 Camk2a Regulation of Regulation of Creb1 1 0.09 0.09 0.62
44 INT96945 Hrh1 Negative_regulation of Spdya 1 0.00 0.32 0.62
45 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
46 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
47 INT166395 CDKN1A Regulation of Gene_expression of IFI27 1 0.32 0.83 0.61
48 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
49 INT166392 IFI27 Regulation of Gene_expression of CDKN1A 1 0.32 0.83 0.61
50 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
51 INT250054 Positive_regulation of Binding of Gpr143 and Spdya 1 0.04 0.52 0.59
52 INT54942 Rb1 Regulation of Gab1 1 0.02 0.39 0.59
53 INT250053 Binding of Gpr143 and Spdya 1 0.03 0.51 0.59
54 INT157141 Cpox Positive_regulation of Gene_expression of Camk2a 1 0.19 0.13 0.58
55 INT296472 Camk2a Positive_regulation of Prkaca 1 0.09 0.32 0.57
56 INT164265 TGM7 Negative_regulation of CDK2 1 0.26 1.08 0.53
57 INT164264 TGM7 Negative_regulation of CCNB1 1 0.07 1.08 0.53
58 INT164262 TGM7 Negative_regulation of E2F1 1 0.16 1.08 0.53
59 INT177504 Gabrg1 Positive_regulation of PCNA 1 0.07 0.22 0.52
60 INT330553 Bcl2l11 Negative_regulation of Camk2a 1 0.01 0.38 0.52
61 INT143861 Nfatc1 Regulation of Gene_expression of NUP214 1 0.00 0.61 0.52
62 INT143859 Bdnf Positive_regulation of Gene_expression of Nfatc1 1 0.00 0.61 0.52
63 INT224853 Binding of Bdnf and Eif4e 1 0.10 0 0.5
64 INT296457 Camk2a Positive_regulation of Phosphorylation of Gria1 1 0.19 0.28 0.49
65 INT58578 Binding of RPA1 and TACR1 1 0.01 0 0.48
66 INT296471 Camk2a Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
67 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
68 INT163040 E2f1 Positive_regulation of Transcription of Oprm1 1 0.00 0 0.46
69 INT306824 Binding of E2F1 and E2F2 1 0.15 0.15 0.46
70 INT20761 INHBA Regulation of Localization of GNRH1 1 0.02 0 0.46
71 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
72 INT319554 Sgk1 Regulation of Cdkn1a 1 0.26 0.09 0.45
73 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
74 INT317521 Camk2a Negative_regulation of Binding of Calm3 1 0.11 0 0.43
75 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
76 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
77 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
78 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
79 INT137834 Binding of CAMK2B and CTS 1 0.05 1.38 0.42
80 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
81 INT273111 Bdnf Positive_regulation of Positive_regulation of Mtor 1 0.44 0.07 0.42
82 INT13879 Binding of PSMB9 and KCNAB2 1 0.03 0.19 0.41
83 INT158032 Binding of CDKN2A and KRT20 1 0.28 0.59 0.4
84 INT98535 Binding of P2rx6 and Spdya 1 0.00 0.1 0.4
85 INT13715 PDYN Positive_regulation of TYMS 1 0.27 0 0.39
86 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
87 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
88 INT71596 Binding of Camk2a and Mpv17l 1 0.00 0 0.38
89 INT85782 Rb1 Regulation of PRKG1 1 0.00 0.38 0.37
90 INT85778 Rb1 Regulation of Prkaca 1 0.00 0.38 0.36
91 INT85779 Rb1 Regulation of Prkcg 1 0.01 0.38 0.36
92 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
93 INT274933 Ephb2 Regulation of Phosphorylation of Camk2a 1 0.29 0 0.36
94 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
95 INT204071 HP Positive_regulation of Gene_expression of CDKN2A 1 0.00 3.48 0.34
96 INT242162 Binding of Ccnd1 and Wnt2 1 0.10 0.23 0.34
97 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
98 INT130803 MC1R Regulation of Positive_regulation of Cdkn2a 1 0.17 0.82 0.34
99 INT204080 HP Negative_regulation of Phosphorylation of Rb1 1 0.00 3.53 0.34
100 INT119262 PPM1E Negative_regulation of Positive_regulation of CDKN1A 1 0.01 0.96 0.33
101 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
102 INT273118 Bdnf Positive_regulation of Mtor 1 0.66 0 0.33
103 INT341215 Binding of Eif4e and Eif4g3 1 0.10 0.41 0.33
104 INT317566 Car2 Positive_regulation of Camk2a 2 0.19 0.58 0.32
105 INT304277 CCNE1 Positive_regulation of IL1RN 1 0.00 1.93 0.31
106 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
107 INT166391 IFI27 Regulation of Gene_expression of CDKN1B 1 0.33 0.41 0.31
108 INT341214 Tas2r130 Positive_regulation of Phosphorylation of Eif4ebp1 1 0.00 0.68 0.31
109 INT304278 CCNE1 Positive_regulation of IL8 1 0.02 1.93 0.31
110 INT317545 Calm3 Positive_regulation of Camk2a 1 0.17 0 0.31
111 INT304280 CCNE1 Positive_regulation of IL6 1 0.00 1.93 0.31
112 INT220521 Ugt1a6b Positive_regulation of Cdkn1b 1 0.01 2.38 0.31
113 INT166397 CDKN1B Regulation of Gene_expression of IFI27 1 0.33 0.41 0.31
114 INT54943 Gab1 Regulation of Rb1 1 0.02 0.2 0.31
115 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3
116 INT243631 Binding of Hand1 and Nfatc1 1 0.04 0.76 0.3
117 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
118 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29
119 INT235874 Camk2a Positive_regulation of Slc6a4 1 0.11 0.14 0.28
120 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
121 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
122 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
123 INT172977 Cdkn1a Negative_regulation of Positive_regulation of Inca1 1 0.00 1.39 0.27
124 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
125 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
126 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
127 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
128 INT237380 Binding of Cdkn2d and Il12b 1 0.01 0.45 0.26
129 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
130 INT147593 Binding of CDK4 and CDKN2A 1 0.42 0.23 0.26
131 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
132 INT147592 Positive_regulation of Binding of CDK4 and CDKN2A 1 0.44 0.23 0.26
133 INT194810 Il4 Regulation of Positive_regulation of Nfatc1 1 0.02 0.15 0.25
134 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
135 INT254283 Il10 Negative_regulation of Nfatc1 1 0.02 0.31 0.25
136 INT35178 Binding of STT3A and PSME3 1 0.01 0.38 0.25
137 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
138 INT296454 Camk2a Positive_regulation of Gene_expression of Gria2 1 0.30 0.14 0.24
139 INT244023 Nsf Regulation of Camk2a 1 0.04 0.09 0.24
140 INT68491 Positive_regulation of Binding of Pomc and Spdya 1 0.00 0 0.24
141 INT296443 Camk2a Positive_regulation of Gria2 1 0.28 0.14 0.24
142 INT296452 Camk2a Positive_regulation of Ltp 1 0.08 0.14 0.24
143 INT245555 Runx1 Negative_regulation of Cdkn1a 1 0.29 1.17 0.23
144 INT245565 Runx1 Negative_regulation of Negative_regulation of Cdkn1a 1 0.29 1.17 0.23
145 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
146 INT264517 PTGDS Positive_regulation of TFDP1 1 0.17 0.5 0.22
147 INT264519 PTGDS Negative_regulation of Positive_regulation of TFDP1 1 0.15 0.5 0.22
148 INT322017 RPA1 Positive_regulation of IL1B 1 0.00 0 0.21
149 INT301290 Tnfsf11 Positive_regulation of Nfatc1 1 0.15 0.65 0.2
150 INT322543 Binding of FOXO3 and Cdkn1b 1 0.08 0.84 0.19
151 INT257232 Negative_regulation of Binding of GRIN1 and Camk2a 1 0.13 0 0.19
152 INT153460 Inhba Positive_regulation of Gene_expression of Ctgf 1 0.77 1.14 0.19
153 INT257234 Binding of GRIN1 and Camk2a 1 0.12 0 0.19
154 INT212084 NOXO1 Positive_regulation of CDKN1A 1 0.06 0.53 0.19
155 INT91862 RPA1 Negative_regulation of Transcription of ATG9B 1 0.03 0.46 0.19
156 INT194830 MAPK1 Positive_regulation of Gene_expression of Nfatc1 1 0.02 0.08 0.19
157 INT58579 Binding of INSRR and RPA1 1 0.00 0 0.18
158 INT170366 Gria1 Regulation of Phosphorylation of Camk2a 1 0.23 0.07 0.18
159 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
160 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
161 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
162 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
163 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
164 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
165 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
166 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
167 INT179846 Il11 Regulation of Positive_regulation of Rps6 1 0.04 0.07 0.17
168 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
169 INT150365 Camk2a Regulation of Gene_expression of Pomc 1 0.08 0.17 0.17
170 INT119264 Binding of RB1 and PPM1E 1 0.00 0.46 0.17
171 INT276065 Camk2a Negative_regulation of Pde1b 1 0.56 0 0.17
172 INT119263 Binding of CDKN1A and PPM1E 1 0.01 0.46 0.17
173 INT327310 Binding of Ccnd1 and Elavl1 1 0.04 0.38 0.16
174 INT349560 Olr779 Negative_regulation of Mtor 1 0.02 0.5 0.16
175 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
176 INT180503 Binding of SARS and PSMD6 1 0.22 2.44 0.16
177 INT226503 BTPs Negative_regulation of Phosphorylation of Nfatc1 1 0.07 0.29 0.16
178 INT221899 Rb1 Positive_regulation of Transcription of Ccl20 1 0.01 0.62 0.16
179 INT221908 Rb1 Positive_regulation of Transcription of TNIP2 1 0.01 0.62 0.16
180 INT243632 Il12a Positive_regulation of Nfatc1 1 0.03 0.44 0.16
181 INT194811 Binding of Crebbp and Nfatc1 1 0.00 0.07 0.16
182 INT194838 Binding of CREB1 and Nfatc1 1 0.01 0.07 0.16
183 INT327325 Binding of Hnrnpd and Ccnd1 1 0.03 0.38 0.16
184 INT194816 MAPK1 Negative_regulation of Phosphorylation of Nfatc1 1 0.01 0.07 0.15
185 INT136855 Arf5 Positive_regulation of Cdkn2a 1 0.07 1.8 0.15
186 INT332327 Camk2a Positive_regulation of Myoz1 1 0.05 0.4 0.15
187 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
188 INT255258 Binding of Rb1 and Tsp1 1 0.38 0.95 0.15
189 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
190 INT301278 Nfatc1 Regulation of Acp5 1 0.05 0.19 0.15
191 INT194836 MAPK1 Negative_regulation of Nfatc1 1 0.01 0.07 0.15
192 INT310263 Rb1 Negative_regulation of Gene_expression of Tnf 1 0.07 0.97 0.15
193 INT273902 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.56 0.15
194 INT196816 Binding of Calm3 and Camk2a 2 0.15 0 0.14
195 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14
196 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14
197 INT349559 Mtor Regulation of Pdpk1 1 0.03 0.42 0.14
198 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
199 INT123192 Bmp6 Positive_regulation of CDKN1A 1 0.18 0.61 0.14
200 INT327879 Binding of Itgb1 and Postn 1 0.02 1.05 0.14

Single Events

The table below shows the top 100 pain related interactions that have been reported for G1/S transition of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in G1/S transition of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
2 INT119528 Positive_regulation of Camk2a 135 0.70 26.13 54.7
3 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
4 INT115649 Gene_expression of Camk2a 95 0.78 33.22 38
5 INT114729 Phosphorylation of Camk2a 110 0.82 15.49 33.19
6 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
7 INT123386 Negative_regulation of Camk2a 48 0.58 12.57 23.78
8 INT69592 Positive_regulation of PSMD1 27 0.70 17.83 18.98
9 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
10 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42
11 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
12 INT151747 Positive_regulation of PSMD2 26 0.68 17.48 17.89
13 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
14 INT115650 Positive_regulation of Gene_expression of Camk2a 37 0.70 17.68 15.73
15 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
16 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99
17 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61
18 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
19 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
20 INT86544 Positive_regulation of Camk2a 20 0.47 4.59 11.37
21 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
22 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
23 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
24 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
25 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
26 INT119527 Regulation of Camk2a 26 0.60 5.55 9.01
27 INT119529 Positive_regulation of Phosphorylation of Camk2a 16 0.60 1.49 8.94
28 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
29 INT71590 Gene_expression of Camk2a 17 0.78 2.3 8.63
30 INT119525 Negative_regulation of Positive_regulation of Camk2a 14 0.43 5.15 8.45
31 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
32 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
33 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
34 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
35 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47
36 INT182440 Gene_expression of CCNE2 39 0.53 22.07 7.44
37 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
38 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34
39 INT228659 Phosphorylation of Eif4ebp1 10 0.80 27.53 6.87
40 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
41 INT132468 Positive_regulation of Positive_regulation of Camk2a 20 0.70 2.76 6.7
42 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
43 INT185879 Gene_expression of CDC6 9 0.39 5.18 6.46
44 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93
45 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
46 INT141151 Regulation of PSMD1 16 0.40 8.19 5.86
47 INT121988 Negative_regulation of Gene_expression of Camk2a 8 0.59 4.76 5.72
48 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
49 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69
50 INT80344 Regulation of Camk2a 9 0.56 0.99 5.66
51 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56
52 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47
53 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38
54 INT151748 Positive_regulation of Positive_regulation of PSMD2 4 0.49 4.45 5.35
55 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
56 INT99549 Gene_expression of CDKN1B 30 0.75 17 5.15
57 INT61312 Positive_regulation of Spdya 3 0.10 0.74 5.12
58 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
59 INT23611 Gene_expression of Mtor 23 0.66 3.57 5.02
60 INT94095 Negative_regulation of BCAT1 9 0.49 0.97 4.91
61 INT147898 Binding of Camk2a 16 0.37 4.01 4.87
62 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
63 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
64 INT17110 Gene_expression of PSMD1 60 0.65 19.57 4.69
65 INT49060 Negative_regulation of Camk2a 10 0.45 2.59 4.67
66 INT151350 Regulation of Gene_expression of Camk2a 1 0.62 0.79 4.57
67 INT71594 Positive_regulation of Gene_expression of Camk2a 8 0.47 1.07 4.35
68 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
69 INT69591 Positive_regulation of Positive_regulation of PSMD1 2 0.50 3.06 3.99
70 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96
71 INT111532 Gene_expression of Nfatc1 15 0.75 5.27 3.73
72 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
73 INT80347 Positive_regulation of Camk2b 2 0.69 0.33 3.67
74 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65
75 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57
76 INT80345 Gene_expression of Camk2b 3 0.77 0.5 3.44
77 INT122997 Phosphorylation of Rps6kb1 46 0.72 9.92 3.43
78 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
79 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
80 INT69593 Negative_regulation of PSMD1 11 0.57 4.06 3.33
81 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28
82 INT127111 Regulation of Inhba 5 0.60 2.85 3.28
83 INT62268 Positive_regulation of Cdkn1a 33 0.67 14.12 3.26
84 INT75500 Negative_regulation of Gene_expression of CCND1 21 0.57 11.59 3.24
85 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21
86 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
87 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
88 INT29929 Gene_expression of Rb1 20 0.69 5.81 3.1
89 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07
90 INT71588 Phosphorylation of Camk2a 7 0.65 0.32 3.03
91 INT101779 Positive_regulation of Positive_regulation of Camk2a 5 0.31 1.57 3.02
92 INT105884 Binding of Bcl2 19 0.35 15.67 3
93 INT228677 Negative_regulation of Phosphorylation of Rps6kb1 24 0.51 3.88 2.97
94 INT51993 Gene_expression of PSMA5 5 0.75 2.59 2.92
95 INT140547 Negative_regulation of PSMB10 3 0.02 2.33 2.92
96 INT77226 Phosphorylation of Eif4ebp1 36 0.09 6.39 2.91
97 INT77339 Positive_regulation of RRM2 5 0.41 1.36 2.88
98 INT75499 Positive_regulation of Positive_regulation of CDKN1A 12 0.60 7.28 2.84
99 INT85078 Positive_regulation of PCNA 36 0.49 17.06 2.81
100 INT80346 Negative_regulation of Camk2b 3 0.58 0.58 2.81
101 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8
102 INT24443 Gene_expression of PSMD2 20 0.54 7.29 2.77
103 INT228678 Phosphorylation of Mtor 15 0.78 3.18 2.76
104 INT54938 Regulation of Rb1 6 0.44 4.41 2.69
105 INT125998 Binding of Camk2a 3 0.36 0.89 2.67
106 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66
107 INT60440 Localization of PSMD1 10 0.74 3.94 2.57
108 INT111528 Positive_regulation of Gene_expression of Nfatc1 5 0.67 3.24 2.52
109 INT99548 Positive_regulation of Gene_expression of CDKN1B 12 0.67 6.79 2.5
110 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48
111 INT127108 Gene_expression of Inhba 12 0.65 3.21 2.48
112 INT338170 Regulation of Regulation of CDKN2A 1 0.44 0.96 2.46
113 INT213681 Gene_expression of TYMS 9 0.33 8.96 2.45
114 INT194748 Positive_regulation of Nfatc1 16 0.64 5.07 2.44
115 INT218822 Negative_regulation of Phosphorylation of Camk2a 5 0.50 0.91 2.41
116 INT86147 Positive_regulation of Inhba 8 0.63 1.94 2.39
117 INT57970 Positive_regulation of Rb1 17 0.67 7.03 2.36
118 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31
119 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
120 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3
121 INT106616 Gene_expression of PSMB9 35 0.72 28.4 2.29
122 INT163283 Gene_expression of E2F1 21 0.71 3.77 2.26
123 INT93396 Positive_regulation of Gene_expression of Ccnd1 13 0.52 8.59 2.26
124 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
125 INT111038 Gene_expression of Cdkn1b 23 0.75 25.35 2.22
126 INT101572 Negative_regulation of Gene_expression of PCNA 24 0.53 13.87 2.21
127 INT217447 Positive_regulation of Positive_regulation of Nfatc1 4 0.46 3.34 2.2
128 INT102908 Phosphorylation of Camk2b 2 0.62 0.42 2.17
129 INT51553 Gene_expression of Spdya 5 0.16 0.58 2.15
130 INT93398 Negative_regulation of Gene_expression of Ccnd1 5 0.44 2.61 2.12
131 INT104402 Positive_regulation of CCND1 15 0.70 11.77 2.08
132 INT94772 Gene_expression of Cdkn2a 14 0.75 8.25 2.04
133 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
134 INT99547 Positive_regulation of CDKN1B 18 0.67 8.42 1.96
135 INT201458 Negative_regulation of Gene_expression of CCNE2 3 0.07 1.71 1.96
136 INT69027 Binding of PSMA5 4 0.47 1.08 1.93
137 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9
138 INT306836 Negative_regulation of Gene_expression of CDC6 1 0.19 1.28 1.88
139 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
140 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
141 INT148493 Regulation of Mnat1 2 0.23 0.8 1.86
142 INT213676 Negative_regulation of Gene_expression of TYMS 2 0.08 1.95 1.83
143 INT174240 Negative_regulation of TYMS 12 0.57 6.35 1.82
144 INT68952 Localization of PCNA 17 0.62 5.64 1.78
145 INT112867 Positive_regulation of Gene_expression of Ccnd1 15 0.56 13.22 1.77
146 INT111534 Regulation of Nfatc1 11 0.29 2.11 1.77
147 INT148721 Binding of PSMD1 13 0.31 4.78 1.76
148 INT168602 Negative_regulation of Itgb1 3 0.21 1.29 1.73
149 INT77227 Positive_regulation of Phosphorylation of Eif4ebp1 11 0.05 2.44 1.67
150 INT88412 Positive_regulation of CDK2 17 0.57 8.49 1.66
151 INT57971 Regulation of Rb1 5 0.41 2.36 1.66
152 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
153 INT86539 Positive_regulation of Phosphorylation of Camk2a 3 0.55 0.18 1.65
154 INT104331 Negative_regulation of Gene_expression of CDKN1A 24 0.57 13.68 1.63
155 INT159185 Positive_regulation of Gene_expression of PSMD2 3 0.40 1.4 1.63
156 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
157 INT136788 Regulation of Eif4e 3 0.61 0 1.61
158 INT76633 Regulation of BCAT1 2 0.04 0.79 1.61
159 INT127110 Transcription of Inhba 3 0.58 1.44 1.59
160 INT119526 Regulation of Gene_expression of Camk2a 4 0.45 1.39 1.58
161 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57
162 INT164152 Negative_regulation of PSMD2 9 0.37 3.41 1.56
163 INT116116 Phosphorylation of CDK4 3 0.56 2.18 1.56
164 INT50077 Gene_expression of Myb 21 0.66 7.68 1.54
165 INT137505 Positive_regulation of Cdkn1b 18 0.67 10.55 1.54
166 INT306844 Localization of CCNE2 6 0.21 3.81 1.52
167 INT306875 Localization of CDC6 1 0.34 1.51 1.52
168 INT12429 Negative_regulation of Spdya 5 0.20 1.07 1.49
169 INT58581 Binding of RPA1 8 0.44 1.68 1.44
170 INT57973 Positive_regulation of ITGB1 5 0.67 1.23 1.44
171 INT69513 Regulation of PSMA5 2 0.60 1.04 1.43
172 INT162811 Localization of Camk2a 4 0.71 0.61 1.42
173 INT166764 Localization of Mtor 2 0.75 1.28 1.42
174 INT108587 Negative_regulation of PSMA5 1 0.57 1.73 1.42
175 INT78470 Negative_regulation of Gene_expression of CDKN2A 14 0.59 14.44 1.38
176 INT201463 Negative_regulation of CCNE2 7 0.39 3.31 1.36
177 INT6018 Positive_regulation of PSMB9 7 0.60 4.36 1.33
178 INT169907 Gene_expression of Rb1 25 0.60 21.95 1.32
179 INT76596 Gene_expression of BCAT1 5 0.58 0.73 1.32
180 INT108327 Negative_regulation of Gene_expression of Ccnd1 18 0.38 14.36 1.31
181 INT219492 Negative_regulation of CDC6 2 0.20 1.74 1.31
182 INT160009 Transcription of CDKN1B 2 0.67 1.43 1.29
183 INT63905 Regulation of RB1 13 0.62 12.67 1.28
184 INT306868 Positive_regulation of Gene_expression of E2F1 6 0.46 1.01 1.28
185 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
186 INT79660 Phosphorylation of PSMC6 3 0.80 0.45 1.28
187 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26
188 INT201466 Positive_regulation of Gene_expression of CCNE2 13 0.20 8.62 1.26
189 INT114220 Negative_regulation of Gene_expression of Cdkn1b 4 0.33 4.11 1.23
190 INT92976 Localization of Camk2a 1 0.61 0.21 1.23
191 INT41124 Negative_regulation of Rb1 11 0.44 3.17 1.22
192 INT20764 Localization of INHBA 3 0.71 0.94 1.22
193 INT228670 Negative_regulation of Rps6kb1 12 0.38 5.27 1.21
194 INT228671 Negative_regulation of Phosphorylation of Mtor 8 0.50 1.77 1.2
195 INT105425 Binding of BCAT1 5 0.42 0.78 1.17
196 INT138529 Positive_regulation of Positive_regulation of Spdya 1 0.10 0 1.17
197 INT228661 Negative_regulation of Phosphorylation of Eif4ebp1 6 0.41 2.25 1.16
198 INT136783 Regulation of Regulation of Eif4e 1 0.45 0 1.16
199 INT128987 Negative_regulation of Ccnd1 24 0.52 15.78 1.15
200 INT20762 Negative_regulation of Localization of INHBA 1 0.03 0 1.15
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