GO:0000123

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Name histone acetyltransferase complex
Categary Component
Go Slim No
Go Link GO:0000123
Unique Molecular Interactions 87
Total Molecular Interactions 123
Total Single Events 522
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for histone acetyltransferase complex. They are ordered first by their pain relevance and then by number of times they were reported for histone acetyltransferase complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT202959 Binding of BAG3 and MCRS1 1 0.11 7.46 3.14
2 INT202958 Binding of STC2 and MCRS1 1 0.01 3.48 1.44
3 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
4 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
5 INT202960 Binding of MCRS1 and CPP 1 0.14 2.49 1.13
6 INT202968 Binding of MCRS1 and CAP1 1 0.03 2.46 1.08
7 INT202967 MCRS1 Negative_regulation of CPP 2 0.14 2.2 0.73
8 INT202972 Positive_regulation of MCRS1 Negative_regulation of CPP 1 0.16 1.64 0.57
9 INT202961 MCRS1 Negative_regulation of STC2 1 0.00 1.63 0.57
10 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
11 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
12 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
13 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
14 INT202957 CPP Negative_regulation of MCRS1 1 0.14 1.53 0.51
15 INT156155 Binding of HCFC1 and TFAM 1 0.04 0.74 0.49
16 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48
17 INT202969 Positive_regulation of SGSM3 Positive_regulation of MCRS1 1 0.02 1.22 0.47
18 INT202964 SGSM3 Positive_regulation of MCRS1 1 0.03 1.21 0.47
19 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
20 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
21 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
22 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
23 INT319729 Binding of Rela and Crebbp 1 0.02 0.88 0.37
24 INT344238 MCRS1 Regulation of TREX1 1 0.08 1.02 0.34
25 INT182837 Binding of Creb1 and Crebbp 1 0.12 0.57 0.32
26 INT156149 Binding of HCFC1 and POU4F1 1 0.27 0.39 0.28
27 INT156154 POU4F1 Positive_regulation of HCFC1 1 0.36 0.38 0.28
28 INT243214 Myst2 Negative_regulation of Gene_expression of Ptgs2 1 0.01 1.4 0.28
29 INT256656 Binding of EP300 and HHIP 1 0.22 0 0.24
30 INT156162 Binding of HCFC1 and CREB3 1 0.13 0.35 0.22
31 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19
32 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19
33 INT119265 Binding of CREBBP and PPM1E 1 0.01 0.46 0.17
34 INT325421 PHF20 Positive_regulation of Localization of Gnrhr 1 0.00 0.39 0.17
35 INT119267 Binding of EP300 and PPM1E 1 0.01 0.46 0.17
36 INT194811 Binding of Crebbp and Nfatc1 1 0.00 0.07 0.16
37 INT194826 Binding of CREB1 and Crebbp 1 0.02 0.07 0.16
38 INT254133 PLEC Regulation of MCRS1 1 0.03 0.33 0.13
39 INT287878 Binding of CREB1 and CREBBP 2 0.01 0.16 0.12
40 INT195662 Binding of PROC and KAT8 1 0.10 2.25 0.12
41 INT319726 Crebbp Positive_regulation of Binding of Rela 1 0.02 0.37 0.12
42 INT319731 Ep300 Positive_regulation of Binding of Rela 1 0.01 0.37 0.12
43 INT156161 Binding of HCFC1 and NFYC 1 0.02 0.36 0.12
44 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11
45 INT243216 Myst2 Positive_regulation of Gene_expression of VEGFA 1 0.00 0.75 0.11
46 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11
47 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11
48 INT243215 Myst2 Negative_regulation of Gene_expression of Icam1 1 0.01 0.68 0.1
49 INT287880 Binding of CREB1 and EP300 1 0.01 0 0.08
50 INT243213 Myst2 Negative_regulation of Alms1 1 0.01 0.91 0.08
51 INT184889 Binding of ALOX5 and MCRS1 1 0.06 1.34 0.07
52 INT119268 CDKN1A Regulation of CREBBP 1 0.21 0.44 0.07
53 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07
54 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06
55 INT337118 MCRS1 Negative_regulation of C7orf49 1 0.00 0.66 0.04
56 INT225569 Binding of Ncoa6 and Ep300 1 0.18 0.63 0.04
57 INT184887 MCRS1 Positive_regulation of ALOX5 1 0.11 0.64 0
58 INT135174 Myst2 Positive_regulation of Binding of Hif1a 1 0.41 0 0
59 INT225562 Binding of Srcs4 and Ep300 1 0.02 0 0
60 INT243106 Binding of Crebbp and Src 1 0.05 0.52 0
61 INT287875 EP300 Negative_regulation of HDAC9 1 0.04 0.51 0
62 INT287882 Binding of CREBBP and HNF4A 1 0.01 0.85 0
63 INT172604 Binding of EP300 and TP53 1 0.00 0 0
64 INT135175 Myst2 Positive_regulation of Hif1a 1 0.41 0 0
65 INT243107 Binding of Src and Ep300 1 0.06 0.17 0
66 INT172606 EP300 Positive_regulation of CREBBP 1 0.00 0.07 0
67 INT235165 Atxn3 Regulation of Transcription of Crebbp 1 0.02 0.3 0
68 INT225619 Binding of TARBP2 and Ep300 1 0.02 0 0
69 INT203674 Myst2 Positive_regulation of Ros1 1 0.00 1.45 0
70 INT172605 Positive_regulation of Binding of EP300 and TP53 1 0.00 0 0
71 INT332963 Atp6v1e1 Negative_regulation of Binding of Crebbp 1 0.08 0 0
72 INT243111 Binding of Crebbp and Ep300 1 0.16 0.17 0
73 INT225543 Binding of D0Nrs1 and Ep300 1 0.01 0 0
74 INT225563 Binding of Tpr and Ep300 1 0.00 0 0
75 INT225622 Binding of STL and Ep300 1 0.01 0 0
76 INT225587 Binding of Kat2b and Cytip 1 0.12 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for histone acetyltransferase complex. They are ordered first by their pain relevance and then by number of times they were reported in histone acetyltransferase complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36
2 INT184895 Gene_expression of MCRS1 46 0.42 56.03 19.44
3 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78
4 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29
5 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
6 INT175554 Binding of MCRS1 21 0.23 25.2 8.59
7 INT2213 Regulation of EP300 10 0.54 4.72 4.5
8 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
9 INT184894 Localization of MCRS1 9 0.47 10.04 3.31
10 INT305617 Positive_regulation of Gene_expression of MCRS1 1 0.05 7.16 2.91
11 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29
12 INT26123 Regulation of Ep300 6 0.23 1.22 2.03
13 INT171514 Binding of EP300 13 0.32 4.32 2.01
14 INT26124 Negative_regulation of Ep300 5 0.37 1.25 1.94
15 INT172622 Localization of EP300 8 0.65 2.56 1.72
16 INT319724 Binding of Crebbp 1 0.16 4.19 1.34
17 INT305616 Negative_regulation of Gene_expression of MCRS1 1 0.04 3.56 1.23
18 INT70821 Positive_regulation of Ep300 4 0.25 1.47 1.2
19 INT202981 Positive_regulation of Binding of MCRS1 3 0.18 4.05 1.02
20 INT158278 Positive_regulation of Myst2 2 0.41 0.89 1.02
21 INT167650 Binding of Ep300 1 0.09 0.14 1
22 INT305620 Regulation of Positive_regulation of MCRS1 1 0.17 2.48 0.99
23 INT117880 Negative_regulation of Crebbp 3 0.38 0.69 0.94
24 INT114922 Phosphorylation of Crebbp 2 0.21 0.92 0.94
25 INT230779 Negative_regulation of Positive_regulation of MCRS1 2 0.04 3.78 0.92
26 INT114956 Gene_expression of CREBBP 5 0.31 1.56 0.75
27 INT74097 Gene_expression of Ep300 6 0.52 1.89 0.73
28 INT158279 Regulation of Myst2 2 0.37 0.51 0.65
29 INT114955 Positive_regulation of Gene_expression of CREBBP 2 0.23 0.24 0.61
30 INT182835 Phosphorylation of Crebbp 2 0.26 0.78 0.54
31 INT117879 Regulation of Crebbp 1 0.24 0 0.54
32 INT182836 Positive_regulation of Crebbp 2 0.21 0.76 0.53
33 INT156166 Binding of HCFC1 4 0.33 1.85 0.51
34 INT203478 Gene_expression of Crebbp 3 0.46 2.15 0.44
35 INT305618 Regulation of Gene_expression of MCRS1 1 0.04 1.24 0.43
36 INT319725 Positive_regulation of Binding of Crebbp 1 0.17 1.12 0.4
37 INT305619 Negative_regulation of Regulation of MCRS1 1 0.04 1.35 0.35
38 INT187587 Binding of Ep300 11 0.35 2.37 0.34
39 INT202982 Transcription of MCRS1 1 0.25 1.19 0.33
40 INT230778 Positive_regulation of Positive_regulation of MCRS1 1 0.03 0.75 0.27
41 INT195678 Binding of KAT8 1 0.16 1.47 0.26
42 INT319719 Negative_regulation of Binding of Crebbp 1 0.14 0.51 0.26
43 INT325492 Regulation of Ep300 1 0.04 0.29 0.24
44 INT195676 Negative_regulation of KAT8 2 0.19 2.63 0.23
45 INT221770 Positive_regulation of Phosphorylation of Crebbp 1 0.14 0.21 0.23
46 INT174663 Positive_regulation of KAT8 4 0.11 3.45 0.22
47 INT212787 Negative_regulation of Binding of EP300 1 0.13 0.53 0.2
48 INT256666 Regulation of Gene_expression of EP300 1 0.14 0.07 0.2
49 INT256661 Regulation of Positive_regulation of EP300 1 0.23 0.07 0.2
50 INT325490 Positive_regulation of Ep300 1 0.03 0.22 0.19
51 INT174662 Regulation of KAT8 2 0.10 1.09 0.18
52 INT184892 Positive_regulation of Localization of MCRS1 2 0.22 1.24 0.16
53 INT298653 Positive_regulation of Binding of EP300 1 0.11 0.8 0.15
54 INT152666 Negative_regulation of CREBBP 2 0.06 0.52 0.14
55 INT27822 Negative_regulation of HCFC1 1 0.58 0.48 0.13
56 INT319722 Positive_regulation of Crebbp 1 0.17 0.62 0.12
57 INT319723 Protein_catabolism of Crebbp 1 0.30 0.56 0.12
58 INT103042 Negative_regulation of Myst2 2 0.04 2.09 0.11
59 INT319721 Gene_expression of Crebbp 2 0.23 0.76 0.11
60 INT171528 Binding of CREBBP 3 0.07 0.47 0.08
61 INT227451 Gene_expression of Myst2 2 0.06 2.98 0.08
62 INT243209 Positive_regulation of Gene_expression of Myst2 1 0.05 0.93 0.08
63 INT292252 Phosphorylation of EP300 1 0.20 0.55 0.05
64 INT319060 Localization of Crebbp 2 0.73 0 0.04
65 INT203460 Negative_regulation of Gene_expression of Crebbp 2 0.25 0.73 0.03
66 INT243077 Regulation of Crebbp 1 0.27 0.13 0.03
67 INT203462 Negative_regulation of Crebbp 1 0.02 0.62 0.03
68 INT243085 Positive_regulation of Gene_expression of Crebbp 1 0.30 0.14 0.03
69 INT187585 Binding of Crebbp 6 0.36 0.11 0
70 INT235154 Transcription of Ep300 2 0.24 1.38 0
71 INT172620 Localization of CREBBP 2 0.09 0.06 0
72 INT337420 Negative_regulation of Localization of Crebbp 1 0.41 0 0
73 INT340511 Localization of Crebbp 1 0.26 0 0
74 INT222914 Negative_regulation of Gene_expression of EP300 1 0.02 0.05 0
75 INT337421 Negative_regulation of Binding of Crebbp 1 0.41 0 0
76 INT276802 Negative_regulation of Gene_expression of CREBBP 1 0.03 0 0
77 INT195675 Gene_expression of KAT8 1 0.30 1.38 0
78 INT340512 Positive_regulation of Gene_expression of Crebbp 1 0.17 0 0
79 INT235158 Transcription of Crebbp 1 0.05 0.29 0
80 INT193368 Gene_expression of HCFC1 1 0.29 0 0
81 INT184893 Negative_regulation of Binding of MCRS1 1 0.19 0.11 0
82 INT243207 Regulation of Gene_expression of Myst2 1 0.04 0.4 0
83 INT332952 Positive_regulation of Binding of Crebbp 1 0.35 0 0
84 INT174666 Localization of KAT8 1 0.11 0.05 0
85 INT135168 Binding of Myst2 1 0.28 0 0
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