GO:0000184

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Name nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Categary Process
Go Slim No
Go Link GO:0000184
Unique Molecular Interactions 127
Total Molecular Interactions 150
Total Single Events 1737
Pain Genes Associated 26

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. They are ordered first by their pain relevance and then by number of times they were reported for nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT349585 Aap Positive_regulation of Etf1 1 0.00 1.68 1.94
2 INT100908 Slc6a3 Regulation of Positive_regulation of Etf1 1 0.05 0 1.41
3 INT51388 Binding of CSF2 and RPLP0 1 0.11 1.8 1.27
4 INT225067 Binding of ETF1 and IGHG3 1 0.03 4.52 1.17
5 INT182159 Binding of HGF and DCPS 1 0.01 2.5 1.17
6 INT290551 Crh Positive_regulation of Etf1 1 0.01 0.38 0.73
7 INT290548 Positive_regulation of Crhr1 Positive_regulation of Etf1 1 0.01 0.38 0.72
8 INT29048 Oprd1 Regulation of Etf1 1 0.00 0 0.71
9 INT142994 Binding of UPF1 and FCMTE1 1 0.00 0.91 0.7
10 INT266489 Dcps Positive_regulation of Gene_expression of Nos2 1 0.06 3.43 0.63
11 INT259768 Positive_regulation of Agtr1a Regulation of Etf1 1 0.00 1.32 0.62
12 INT225065 Binding of ETF1 and FANCB 1 0.01 2.07 0.59
13 INT225083 Binding of ETF1 and fc 1 0.00 2.13 0.57
14 INT310701 RPLP0 Regulation of Positive_regulation of PGR 1 0.01 0.49 0.53
15 INT182150 Binding of APC and DCPS 1 0.02 1.14 0.48
16 INT142826 UPF1 Positive_regulation of CREB1 1 0.11 0 0.46
17 INT310711 Binding of RPLP0 and Gabrg1 1 0.04 0.37 0.45
18 INT182158 Binding of IL3RA and DCPS 1 0.06 0.77 0.39
19 INT67031 Ins1 Regulation of Etf1 1 0.01 0.69 0.37
20 INT329170 DCPS Positive_regulation of Gene_expression of IFN1@ 1 0.04 1.55 0.36
21 INT67030 Negative_regulation of Adra2a Negative_regulation of Etf1 1 0.00 0.64 0.33
22 INT175552 Binding of CASR and UPF1 1 0.01 0.89 0.33
23 INT67029 Adra2a Negative_regulation of Etf1 1 0.00 0.64 0.33
24 INT321917 1200011M11Rik Positive_regulation of DAO 1 0.01 0.9 0.27
25 INT156156 Positive_regulation of Binding of NGF and SMG1 1 0.03 0.41 0.26
26 INT355982 Binding of HLA-DQA2 and DCPS 1 0.00 1.33 0.26
27 INT310700 PGR Regulation of Gene_expression of RPLP0 1 0.01 0.37 0.25
28 INT355983 CSF2 Regulation of Gene_expression of DCPS 1 0.02 0.84 0.25
29 INT156157 Binding of NGF and SMG1 1 0.02 0.4 0.23
30 INT355985 IDO1 Positive_regulation of Gene_expression of DCPS 1 0.02 1.21 0.23
31 INT337168 DCPS Negative_regulation of CD86 1 0.02 1.54 0.21
32 INT277318 Upf1 Positive_regulation of Atxn8os 1 0.01 0.77 0.21
33 INT225649 IL4 Positive_regulation of Localization of DCPS 1 0.02 1.03 0.19
34 INT246970 Binding of Clns1a and Dcps 1 0.05 0.42 0.18
35 INT246968 Binding of Csf2 and Dcps 1 0.14 0.42 0.18
36 INT182152 DCPS Positive_regulation of IFNA1 1 0.02 0.45 0.18
37 INT182149 DCPS Positive_regulation of Binding of IFNA1 1 0.02 0.45 0.18
38 INT182155 DCPS Positive_regulation of Positive_regulation of ITGAX 1 0.04 0.46 0.18
39 INT299495 EXOSC10 Regulation of IL6 1 0.01 0.59 0.17
40 INT299496 EXOSC10 Regulation of CSRP1 1 0.00 0.59 0.17
41 INT218937 Akt1 Positive_regulation of Parn 1 0.01 0.65 0.16
42 INT277433 Wibg Positive_regulation of Gdnf 1 0.01 0.6 0.13
43 INT277430 Wibg Positive_regulation of Gene_expression of Gdnf 1 0.01 0.6 0.13
44 INT182154 Binding of HLA-DRA and DCPS 1 0.01 0.23 0.12
45 INT118587 Binding of UPF1 and CLEC4F 1 0.00 0.22 0.1
46 INT277316 Upf1 Positive_regulation of Slc6a11 1 0.01 0.47 0.09
47 INT299491 Binding of IL6 and EXOSC10 1 0.01 0.44 0.08
48 INT103810 Binding of PTPRC and RPL26 1 0.09 1.01 0.08
49 INT264188 DCPS Positive_regulation of Gene_expression of IL10 1 0.02 0.59 0.08
50 INT225650 DCPS Positive_regulation of PDHA1 1 0.00 0.41 0.07
51 INT84752 Binding of HRAS and DCPS 1 0.18 2.61 0.07
52 INT174901 Binding of GSPT2 and GTSE1 1 0.01 1.28 0.07
53 INT265386 DCPS Positive_regulation of Localization of CXCL10 1 0.01 0.07 0.05
54 INT353667 Binding of CXCL10 and DCPS 1 0.00 0.34 0.04
55 INT350737 Binding of CALM1 and ETF1 1 0.00 0 0.04
56 INT293899 UPF1 Positive_regulation of Gene_expression of APOB 1 0.01 0 0.04
57 INT353670 Binding of DCPS and SENP8 1 0.00 0.34 0.04
58 INT315678 Binding of MPZ and UPF1 1 0.00 2.05 0.04
59 INT191923 Binding of EXOSC10 and Tlr4 1 0.21 0.48 0.04
60 INT290437 Gene_expression of Mef2c Negative_regulation of Upf1 1 0.02 0.25 0.03
61 INT191899 Binding of EXOSC10 and PNN 1 0.00 0.96 0.03
62 INT351466 NMD3 Positive_regulation of Protein_catabolism of UPF1 1 0.00 0.54 0
63 INT248497 Positive_regulation of Upf1 Positive_regulation of Pdss1 1 0.01 0.15 0
64 INT318081 Binding of RPL5 and UBC 1 0.02 0.52 0
65 INT248494 Upf1 Positive_regulation of Pdss1 1 0.01 0.15 0
66 INT211779 Binding of EIF4G1 and NTSR1 1 0.02 0 0
67 INT248501 Binding of Upf1 and Pdss1 1 0.01 0.21 0
68 INT262915 ENPP2 Regulation of SMG1 1 0.22 0.07 0
69 INT353660 Binding of ICAM3 and DCPS 1 0.01 1.43 0
70 INT191900 Binding of EXOSC10 and COPD 1 0.01 0.53 0
71 INT262914 SMG1 Positive_regulation of LPA 1 0.03 0 0
72 INT307284 DCP2 Positive_regulation of HAL 1 0.00 0 0
73 INT277811 Binding of CD28 and DCPS 1 0.04 0.05 0
74 INT309734 Binding of CALM3 and RPLP2 1 0.01 0 0
75 INT311392 Binding of Cnbp and Pabpc1 1 0.04 0.14 0
76 INT318102 Binding of RPL5 and Ldha 1 0.08 0.66 0
77 INT248492 Upf1 Positive_regulation of Smn1 1 0.03 0.15 0
78 INT217859 Binding of CXADR and RPS4X 1 0.03 0.17 0
79 INT277312 Regulation of Binding of Upf1 and Mbnl1 1 0.01 0.36 0
80 INT171478 Binding of DBP and RPL6 1 0.00 0.26 0
81 INT318101 Binding of RPL5 and Ppia 1 0.07 0.52 0
82 INT295871 Binding of RNPS1 and Srpk2 1 0.01 0.76 0
83 INT273596 SMG1 Regulation of Negative_regulation of ADHD1 1 0.16 0.41 0
84 INT277309 Binding of Upf1 and Mbnl1 1 0.01 0.71 0
85 INT277308 Upf1 Regulation of Regulation of Celf1 1 0.00 1.05 0
86 INT255290 Snap25 Positive_regulation of Gene_expression of Upf1 1 0.02 0 0
87 INT217860 Binding of RPS4X and AD5 1 0.03 0.64 0
88 INT248500 Positive_regulation of Upf1 Positive_regulation of Smn1 1 0.03 0.15 0
89 INT307286 Binding of PMP2 and DCP2 1 0.04 0 0
90 INT311377 Binding of Eef2 and Pabpc1 1 0.01 0.15 0
91 INT213869 Binding of RBM8A and Mar1 1 0.00 0 0
92 INT342439 PPP2CA Negative_regulation of PRMT1 1 0.12 0.63 0
93 INT172981 PAN3 Negative_regulation of SMAD4 1 0.01 0.98 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. They are ordered first by their pain relevance and then by number of times they were reported in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT29046 Positive_regulation of Etf1 32 0.12 12.03 21.06
2 INT45142 Gene_expression of DCPS 109 0.56 84.71 16.87
3 INT29047 Negative_regulation of Etf1 18 0.08 9.6 11.12
4 INT159631 Positive_regulation of DCPS 60 0.27 43.23 10.3
5 INT73223 Gene_expression of UPF1 78 0.41 31.44 9.94
6 INT29045 Regulation of Etf1 10 0.05 5.93 8.7
7 INT159632 Localization of DCPS 24 0.21 18.24 6.8
8 INT54782 Localization of Etf1 7 0.13 0.8 5.85
9 INT154303 Negative_regulation of DCPS 27 0.36 33.83 5.45
10 INT59836 Positive_regulation of Upf1 24 0.02 4.42 3.99
11 INT94303 Gene_expression of Upf1 44 0.04 11.62 3.87
12 INT143494 Binding of DCPS 24 0.29 24.41 3.67
13 INT167478 Positive_regulation of Gene_expression of DCPS 23 0.27 14.75 3.37
14 INT100905 Gene_expression of Etf1 4 0.11 1.11 3.09
15 INT200963 Regulation of UPF1 10 0.01 2.18 2.67
16 INT120650 Negative_regulation of UPF1 14 0.02 6.86 2.14
17 INT246955 Gene_expression of Dcps 19 0.31 12.26 2.12
18 INT148702 Positive_regulation of UPF1 29 0.31 12.9 1.91
19 INT67862 Negative_regulation of ETF1 3 0.29 1.45 1.91
20 INT198568 Regulation of DCPS 17 0.34 16.26 1.86
21 INT59837 Regulation of Upf1 5 0.03 1.37 1.45
22 INT103907 Negative_regulation of Upf1 15 0.37 4.3 1.4
23 INT200979 Regulation of Gene_expression of UPF1 4 0.28 2.19 1.31
24 INT159360 Positive_regulation of SMG1 11 0.67 2.01 1.29
25 INT67254 Gene_expression of RPLP0 6 0.38 2.7 1.24
26 INT200972 Positive_regulation of Gene_expression of UPF1 6 0.31 1.51 1.23
27 INT103164 Binding of UPF1 4 0.29 4.15 1.22
28 INT159361 Negative_regulation of Positive_regulation of SMG1 1 0.57 0.98 1.15
29 INT107592 Gene_expression of SMG1 42 0.74 11.16 1.13
30 INT29044 Positive_regulation of Negative_regulation of Etf1 2 0.01 0.99 1.13
31 INT290531 Positive_regulation of Etf1 1 0.01 2.17 1.13
32 INT246953 Localization of Dcps 5 0.32 1.89 1.06
33 INT67863 Positive_regulation of Negative_regulation of ETF1 1 0.35 0.14 0.92
34 INT182167 Transcription of DCPS 1 0.11 1.94 0.82
35 INT355989 Positive_regulation of Localization of DCPS 1 0.05 1.83 0.8
36 INT100906 Regulation of Positive_regulation of Etf1 1 0.05 0 0.79
37 INT117427 Gene_expression of Parn 1 0.44 1.18 0.79
38 INT100907 Negative_regulation of Positive_regulation of Etf1 1 0.07 0 0.78
39 INT182182 Positive_regulation of Positive_regulation of DCPS 4 0.08 3.32 0.7
40 INT246954 Binding of Dcps 4 0.15 2.95 0.7
41 INT200961 Transcription of UPF1 2 0.01 0.52 0.67
42 INT304293 Positive_regulation of Negative_regulation of DCPS 2 0.08 3.17 0.64
43 INT200949 Negative_regulation of Gene_expression of UPF1 1 0.01 0.81 0.64
44 INT225072 Binding of ETF1 1 0.02 2.55 0.63
45 INT156169 Binding of SMG1 8 0.35 2.84 0.62
46 INT145142 Gene_expression of RPL5 3 0.12 1.54 0.62
47 INT67860 Positive_regulation of ETF1 3 0.23 0.49 0.62
48 INT159634 Negative_regulation of Positive_regulation of DCPS 2 0.13 2.39 0.58
49 INT191905 Binding of EXOSC10 19 0.04 11.24 0.57
50 INT191904 Positive_regulation of EXOSC10 11 0.06 5.43 0.57
51 INT184815 Regulation of ETF1 3 0.40 1.83 0.54
52 INT182178 Regulation of Gene_expression of DCPS 4 0.07 3.16 0.51
53 INT67864 Positive_regulation of Positive_regulation of ETF1 2 0.23 0.07 0.5
54 INT35619 Positive_regulation of Localization of RNPS1 1 0.01 0 0.49
55 INT304297 Negative_regulation of Negative_regulation of DCPS 4 0.08 4.43 0.47
56 INT67861 Negative_regulation of Positive_regulation of ETF1 1 0.22 0.07 0.46
57 INT254389 Negative_regulation of Gene_expression of DCPS 6 0.08 7.26 0.44
58 INT349073 Localization of ETF1 1 0.11 0 0.44
59 INT200975 Positive_regulation of Transcription of UPF1 1 0.01 0.22 0.42
60 INT246956 Positive_regulation of Dcps 1 0.20 0.33 0.41
61 INT246951 Positive_regulation of Gene_expression of Dcps 1 0.20 0.5 0.39
62 INT59838 Positive_regulation of Positive_regulation of Upf1 3 0.01 0.64 0.37
63 INT159633 Negative_regulation of Localization of DCPS 1 0.13 0.1 0.34
64 INT164993 Positive_regulation of Gene_expression of SMG1 4 0.66 0.69 0.29
65 INT210645 Regulation of SMG1 5 0.40 1.15 0.27
66 INT240203 Regulation of Transcription of UPF1 1 0.01 0.3 0.26
67 INT266487 Regulation of Dcps 1 0.05 0.97 0.25
68 INT35618 Localization of RNPS1 1 0.01 0 0.24
69 INT120649 Localization of UPF1 3 0.03 0.93 0.22
70 INT225077 Positive_regulation of Binding of ETF1 1 0.03 0.82 0.21
71 INT310703 Negative_regulation of Gene_expression of RPLP0 1 0.04 0.68 0.21
72 INT266485 Protein_catabolism of Dcps 1 0.08 1.08 0.2
73 INT220729 Positive_regulation of Gene_expression of ETF1 1 0.01 0.82 0.2
74 INT210643 Localization of SMG1 2 0.58 0.65 0.19
75 INT138681 Gene_expression of PAN3 2 0.05 1.77 0.18
76 INT218902 Phosphorylation of Parn 1 0.03 0.64 0.16
77 INT200005 Positive_regulation of Binding of DCPS 1 0.02 0.87 0.14
78 INT353246 Gene_expression of EIF4G1 1 0.06 1.23 0.14
79 INT200943 Negative_regulation of PPP2CA 1 0.10 0.13 0.14
80 INT237845 Localization of DCP2 2 0.43 1.16 0.13
81 INT259770 Binding of Etf1 1 0.01 0.19 0.12
82 INT70016 Protein_catabolism of Upf1 1 0.00 0 0.12
83 INT246947 Transcription of Dcps 1 0.28 0.85 0.11
84 INT193178 Gene_expression of ETF1 2 0.09 0.56 0.1
85 INT77286 Binding of RPLP0 2 0.21 0.58 0.1
86 INT337213 Regulation of Positive_regulation of DCPS 1 0.02 0.7 0.1
87 INT262931 Negative_regulation of Gene_expression of SMG1 3 0.25 1.14 0.09
88 INT210644 Negative_regulation of SMG1 3 0.34 0.88 0.09
89 INT146316 Positive_regulation of RPS4X 1 0.67 0.86 0.09
90 INT191908 Negative_regulation of Positive_regulation of EXOSC10 1 0.01 0.25 0.09
91 INT300510 Gene_expression of Wibg 1 0.01 0.88 0.09
92 INT153698 Negative_regulation of Positive_regulation of UPF1 1 0.08 0.72 0.09
93 INT300509 Regulation of Gene_expression of Wibg 1 0.01 0.89 0.09
94 INT86725 Positive_regulation of GSPT2 1 0.01 0.66 0.08
95 INT154717 Regulation of Binding of DCPS 1 0.35 1.76 0.08
96 INT191906 Positive_regulation of Positive_regulation of EXOSC10 2 0.04 0.66 0.07
97 INT318117 Positive_regulation of PAN3 1 0.01 0.94 0.07
98 INT293912 Protein_catabolism of UPF1 3 0.02 1.2 0.05
99 INT246948 Regulation of Gene_expression of Dcps 1 0.18 1.02 0.05
100 INT295864 Phosphorylation of RNPS1 1 0.02 0.81 0.04
101 INT307299 Binding of DCP2 1 0.06 0 0.03
102 INT171522 Negative_regulation of RPL6 1 0.23 0.1 0.03
103 INT210093 Gene_expression of EXOSC10 5 0.65 2.31 0
104 INT262926 Regulation of Gene_expression of SMG1 3 0.19 0.22 0
105 INT248486 Binding of Upf1 2 0.02 0.99 0
106 INT256198 Positive_regulation of Gene_expression of EXOSC10 1 0.49 0.56 0
107 INT237848 Positive_regulation of Localization of DCP2 1 0.29 0.94 0
108 INT172468 Transcription of Pabpc1 1 0.67 0.06 0
109 INT351507 Localization of RPLP0 1 0.38 0.1 0
110 INT237844 Gene_expression of DCP2 1 0.39 1.1 0
111 INT296804 Regulation of Negative_regulation of SMG1 1 0.19 0 0
112 INT211840 Protein_catabolism of EIF4G1 1 0.35 0.13 0
113 INT211836 Binding of EIF4G1 1 0.12 0.07 0
114 INT172469 Positive_regulation of Pabpc1 1 0.49 0.06 0
115 INT225658 Protein_catabolism of DCPS 1 0.08 0.24 0
116 INT171519 Binding of RPL6 1 0.15 0.26 0
117 INT57152 Negative_regulation of GSPT2 1 0.36 0 0
118 INT191907 Positive_regulation of Binding of EXOSC10 1 0.01 0.36 0
119 INT210091 Regulation of EXOSC10 1 0.04 0.54 0
120 INT296803 Negative_regulation of Protein_catabolism of SMG1 1 0.18 0 0
121 INT307904 Negative_regulation of Positive_regulation of Upf1 1 0.01 0.32 0
122 INT210094 Negative_regulation of EXOSC10 1 0.03 0.15 0
123 INT173011 Localization of PAN3 1 0.01 0.91 0
124 INT172470 Positive_regulation of Transcription of Pabpc1 1 0.49 0.06 0
125 INT351496 Positive_regulation of RPLP0 1 0.25 0.52 0
126 INT342452 Gene_expression of PPP2CA 1 0.20 0.49 0
127 INT217871 Binding of RPS4X 1 0.05 0.19 0
128 INT275456 Binding of Pabpc1 1 0.24 1.62 0
129 INT310350 Positive_regulation of Positive_regulation of UPF1 1 0.31 0 0
130 INT295861 Binding of RNPS1 1 0.01 0.76 0
131 INT296802 Protein_catabolism of SMG1 1 0.37 0 0
132 INT351495 Positive_regulation of Gene_expression of RPLP0 1 0.25 0.54 0
133 INT237841 Positive_regulation of Gene_expression of DCP2 1 0.29 0.3 0
134 INT342450 Positive_regulation of PPP2CA 1 0.15 1.07 0
135 INT277276 Positive_regulation of Gene_expression of Upf1 1 0.01 1.04 0
136 INT309761 Binding of RPLP2 1 0.03 0 0
137 INT307294 Negative_regulation of Binding of DCP2 1 0.05 0 0
138 INT248465 Localization of Upf1 1 0.04 0.3 0
139 INT310351 Positive_regulation of Binding of UPF1 1 0.31 0 0
140 INT312673 Gene_expression of RPLP2 1 0.09 0 0
141 INT312677 Transcription of RPLP2 1 0.10 0 0
142 INT307298 Regulation of DCP2 1 0.05 0 0
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