GO:0000216

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Name M/G1 transition of mitotic cell cycle
Categary Process
Go Slim No
Go Link GO:0000216
Unique Molecular Interactions 51
Total Molecular Interactions 84
Total Single Events 654
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for M/G1 transition of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for M/G1 transition of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
2 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
3 INT79602 Binding of PSMA5 and Oprd1 2 0.19 1.05 1.01
4 INT144286 ACP1 Negative_regulation of Phosphorylation of PSMC6 1 0.45 0.39 0.78
5 INT164265 TGM7 Negative_regulation of CDK2 1 0.26 1.08 0.53
6 INT58578 Binding of RPA1 and TACR1 1 0.01 0 0.48
7 INT13879 Binding of PSMB9 and KCNAB2 1 0.03 0.19 0.41
8 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29
9 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
10 INT35178 Binding of STT3A and PSME3 1 0.01 0.38 0.25
11 INT322017 RPA1 Positive_regulation of IL1B 1 0.00 0 0.21
12 INT91862 RPA1 Negative_regulation of Transcription of ATG9B 1 0.03 0.46 0.19
13 INT58579 Binding of INSRR and RPA1 1 0.00 0 0.18
14 INT180503 Binding of SARS and PSMD6 1 0.22 2.44 0.16
15 INT88410 BMP7 Negative_regulation of CDK2 1 0.35 0 0.14
16 INT184953 Binding of CDC6 and PCNA 1 0.05 0.19 0.13
17 INT57014 PSMB1 Regulation of SCN5A 1 0.02 0 0.1
18 INT298351 PSMD1 Regulation of Gene_expression of HLA-DRA 1 0.01 0.42 0.08
19 INT298356 PSMD1 Regulation of Gene_expression of Cd14 1 0.04 0.42 0.08
20 INT166784 Binding of PSMD1 and Nkx6-2 1 0.21 0.5 0.08
21 INT88411 Positive_regulation of PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
22 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07
23 INT88408 PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
24 INT231605 Binding of PSMD1 and SGCG 1 0.02 0.34 0.04
25 INT250151 Binding of GSS and MCM3 1 0.01 1.38 0.04
26 INT261728 PSMB6 Negative_regulation of Transcription of F2R 1 0.01 0.17 0.03
27 INT261731 PSMB6 Regulation of COL5A2 1 0.00 0.21 0.03
28 INT287479 PSMB10 Positive_regulation of TBK1 1 0.00 0.59 0.03
29 INT289608 Binding of CDK2 and CCNE2 5 0.06 4.89 0
30 INT219412 CDK2 Regulation of PCNA 1 0.20 0.11 0
31 INT318081 Binding of RPL5 and UBC 1 0.02 0.52 0
32 INT209454 Binding of PSMD1 and PSMD2 1 0.15 0 0
33 INT165318 Binding of PSMD1 and CHPT1 1 0.23 0.57 0
34 INT325156 CDKN1B Negative_regulation of CDK2 1 0.49 0.11 0
35 INT276607 Binding of DBT and PSMD1 1 0.00 0.08 0
36 INT209452 Binding of PSMD2 and PSMD3 1 0.07 0.2 0
37 INT318103 Binding of UBC and Hprt 1 0.10 0.52 0
38 INT219426 CDK2 Regulation of HNF4A 1 0.01 0.11 0
39 INT299698 Binding of CFB and PSMC2 1 0.00 0.14 0
40 INT314688 Binding of CCNE1 and CDK2 1 0.04 1.41 0
41 INT209453 Binding of PSMD1 and PSMD3 1 0.08 0.2 0
42 INT219413 CDK2 Regulation of SKP2 1 0.23 0.11 0
43 INT274387 Binding of POLA1 and IGSF9 1 0.01 0.58 0
44 INT175194 Binding of UBC and NUP62 1 0.01 0.05 0
45 INT322544 Binding of CDK2 and Ccne1 1 0.16 0 0
46 INT322503 Negative_regulation of Binding of CDK2 and CCNE2 1 0.01 0.25 0
47 INT299708 Binding of C3 and PSMC2 1 0.00 0.14 0
48 INT219419 CDK2 Regulation of E2F2 1 0.23 0.11 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for M/G1 transition of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in M/G1 transition of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69592 Positive_regulation of PSMD1 27 0.70 17.83 18.98
2 INT151747 Positive_regulation of PSMD2 26 0.68 17.48 17.89
3 INT185879 Gene_expression of CDC6 9 0.39 5.18 6.46
4 INT141151 Regulation of PSMD1 16 0.40 8.19 5.86
5 INT151748 Positive_regulation of Positive_regulation of PSMD2 4 0.49 4.45 5.35
6 INT17110 Gene_expression of PSMD1 60 0.65 19.57 4.69
7 INT69591 Positive_regulation of Positive_regulation of PSMD1 2 0.50 3.06 3.99
8 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96
9 INT69593 Negative_regulation of PSMD1 11 0.57 4.06 3.33
10 INT51993 Gene_expression of PSMA5 5 0.75 2.59 2.92
11 INT140547 Negative_regulation of PSMB10 3 0.02 2.33 2.92
12 INT24443 Gene_expression of PSMD2 20 0.54 7.29 2.77
13 INT60440 Localization of PSMD1 10 0.74 3.94 2.57
14 INT106616 Gene_expression of PSMB9 35 0.72 28.4 2.29
15 INT69027 Binding of PSMA5 4 0.47 1.08 1.93
16 INT306836 Negative_regulation of Gene_expression of CDC6 1 0.19 1.28 1.88
17 INT148721 Binding of PSMD1 13 0.31 4.78 1.76
18 INT88412 Positive_regulation of CDK2 17 0.57 8.49 1.66
19 INT159185 Positive_regulation of Gene_expression of PSMD2 3 0.40 1.4 1.63
20 INT164152 Negative_regulation of PSMD2 9 0.37 3.41 1.56
21 INT306875 Localization of CDC6 1 0.34 1.51 1.52
22 INT58581 Binding of RPA1 8 0.44 1.68 1.44
23 INT69513 Regulation of PSMA5 2 0.60 1.04 1.43
24 INT108587 Negative_regulation of PSMA5 1 0.57 1.73 1.42
25 INT6018 Positive_regulation of PSMB9 7 0.60 4.36 1.33
26 INT219492 Negative_regulation of CDC6 2 0.20 1.74 1.31
27 INT79660 Phosphorylation of PSMC6 3 0.80 0.45 1.28
28 INT91872 Gene_expression of RPA1 9 0.77 5.28 1.12
29 INT67638 Positive_regulation of PSMA5 1 0.21 1.15 1.05
30 INT106735 Phosphorylation of CDK2 11 0.79 4.03 1.02
31 INT13882 Binding of PSMB9 3 0.15 2.84 1
32 INT306847 Positive_regulation of Gene_expression of CDC6 1 0.23 0.16 0.99
33 INT184992 Positive_regulation of CDC6 2 0.28 0.7 0.96
34 INT78322 Positive_regulation of PSME1 2 0.44 1.8 0.95
35 INT144289 Negative_regulation of Positive_regulation of PSMC6 1 0.41 0.56 0.92
36 INT306882 Transcription of CDC6 1 0.24 0.57 0.92
37 INT144287 Positive_regulation of PSMC6 1 0.49 0.56 0.92
38 INT78323 Negative_regulation of PSME1 1 0.37 0.5 0.78
39 INT108590 Negative_regulation of Negative_regulation of PSMA5 1 0.57 0.92 0.75
40 INT105330 Gene_expression of CDK2 31 0.63 13.7 0.67
41 INT108586 Positive_regulation of Negative_regulation of PSMA5 1 0.49 0.82 0.67
42 INT113846 Negative_regulation of Positive_regulation of CDK2 1 0.48 0.39 0.6
43 INT17109 Regulation of Gene_expression of PSMD1 3 0.44 0.86 0.58
44 INT16681 Positive_regulation of PSMC2 1 0.07 0 0.54
45 INT163285 Negative_regulation of Phosphorylation of CDK2 2 0.32 0.52 0.48
46 INT350879 Negative_regulation of Localization of PSMD1 1 0.05 0.43 0.43
47 INT202762 Gene_expression of PSMD3 8 0.47 1.44 0.42
48 INT280564 Negative_regulation of Gene_expression of PSMB9 5 0.54 5.99 0.41
49 INT78324 Regulation of PSME1 1 0.61 0.49 0.41
50 INT58580 Positive_regulation of Binding of RPA1 2 0.43 0 0.38
51 INT280560 Positive_regulation of Gene_expression of PSMB9 7 0.64 6.44 0.36
52 INT335718 Regulation of Gene_expression of PSMD2 1 0.09 0.07 0.35
53 INT11689 Binding of PSMD2 16 0.36 2.77 0.34
54 INT57019 Gene_expression of PSMB1 1 0.38 0 0.34
55 INT11688 Binding of PSMD3 5 0.36 1.17 0.28
56 INT184987 Regulation of CDC6 2 0.12 0.27 0.25
57 INT131823 Negative_regulation of PSMB6 2 0.01 0.09 0.24
58 INT106733 Regulation of CDK2 6 0.44 4.76 0.23
59 INT322282 Localization of PSMD2 2 0.20 1.42 0.22
60 INT209076 Negative_regulation of PSME3 2 0.34 0.86 0.21
61 INT165973 Phosphorylation of PSMA5 1 0.79 0.07 0.2
62 INT165972 Positive_regulation of Phosphorylation of PSMA5 1 0.49 0.07 0.2
63 INT280553 Regulation of PSMB9 2 0.57 1.46 0.19
64 INT209077 Positive_regulation of Negative_regulation of PSME3 1 0.37 0.13 0.19
65 INT163284 Negative_regulation of Gene_expression of CDK2 5 0.32 1.6 0.16
66 INT57020 Transcription of PSMB1 1 0.26 0 0.16
67 INT91870 Negative_regulation of Gene_expression of RPA1 1 0.58 0.4 0.16
68 INT90493 Negative_regulation of PSMB9 3 0.54 0.88 0.15
69 INT91871 Transcription of RPA1 1 0.69 0.38 0.15
70 INT91866 Positive_regulation of Gene_expression of RPA1 1 0.69 0.38 0.15
71 INT185019 Binding of CDC6 2 0.21 0.31 0.13
72 INT184998 Negative_regulation of Binding of CDC6 1 0.11 0.19 0.13
73 INT201462 Binding of CDK2 12 0.39 5.2 0.12
74 INT15564 Regulation of PSMD2 1 0.00 0 0.12
75 INT165320 Protein_catabolism of PSMD1 1 0.61 1.37 0.11
76 INT165319 Regulation of Protein_catabolism of PSMD1 1 0.31 1.37 0.11
77 INT334958 Positive_regulation of Localization of PSMD1 1 0.10 0.87 0.1
78 INT226076 Regulation of RPA1 1 0.25 0.43 0.1
79 INT201460 Positive_regulation of Gene_expression of CDK2 5 0.52 2.8 0.09
80 INT169428 Regulation of Gene_expression of CDK2 4 0.46 1.03 0.09
81 INT106732 Regulation of Phosphorylation of CDK2 2 0.44 0.8 0.09
82 INT194320 Localization of RPA1 2 0.06 0.17 0.09
83 INT302272 Localization of CDK2 2 0.30 1.09 0.09
84 INT280554 Negative_regulation of Positive_regulation of PSMB9 1 0.40 0.9 0.09
85 INT189116 Gene_expression of PSMB10 1 0.18 0.3 0.08
86 INT285256 Positive_regulation of Negative_regulation of PSMD2 1 0.04 0 0.08
87 INT337665 Positive_regulation of PSME3 1 0.45 2.51 0.07
88 INT166204 Gene_expression of PSME1 3 0.32 1.94 0.05
89 INT202765 Positive_regulation of PSMD3 1 0.12 0.51 0.05
90 INT263801 Localization of PSME1 2 0.07 1.72 0.04
91 INT318095 Gene_expression of UBC 1 0.16 1.24 0.04
92 INT337650 Positive_regulation of Positive_regulation of PSME3 1 0.32 1.33 0.04
93 INT337661 Positive_regulation of Positive_regulation of PSME1 1 0.05 1.31 0.04
94 INT337662 Localization of PSME3 1 0.52 1.26 0.04
95 INT186663 Protein_catabolism of PSMB9 2 0.60 0.39 0.03
96 INT266166 Negative_regulation of RPA1 2 0.08 1.65 0.03
97 INT201468 Negative_regulation of Binding of CDK2 2 0.17 1.1 0.03
98 INT214219 Regulation of PSMD6 1 0.01 0.05 0.03
99 INT214220 Gene_expression of PSMD6 3 0.65 0.83 0
100 INT169427 Transcription of CDK2 2 0.09 0.42 0
101 INT227884 Positive_regulation of Gene_expression of PSMD1 2 0.06 0.4 0
102 INT87528 Negative_regulation of PSMC6 2 0.41 0 0
103 INT155591 Binding of PSME1 2 0.07 0.49 0
104 INT310442 Gene_expression of POLA1 1 0.30 0.97 0
105 INT299146 Positive_regulation of RPA1 1 0.01 0.15 0
106 INT285901 Regulation of Transcription of CDK2 1 0.03 0.7 0
107 INT248587 Positive_regulation of Gene_expression of PSMD3 1 0.04 0.16 0
108 INT250154 Binding of MCM3 1 0.01 0.57 0
109 INT166205 Negative_regulation of Gene_expression of PSME1 1 0.18 0.28 0
110 INT222070 Localization of PSMD3 1 0.04 0.09 0
111 INT302263 Regulation of Phosphorylation of PSMD6 1 0.09 0.84 0
112 INT209457 Negative_regulation of Gene_expression of PSMD1 1 0.27 0.2 0
113 INT175213 Negative_regulation of Binding of UBC 1 0.02 0.13 0
114 INT157670 Regulation of PSMC6 1 0.44 0.58 0
115 INT245611 Positive_regulation of Binding of PSMD2 1 0.43 0.1 0
116 INT156902 Positive_regulation of UBC 1 0.49 0 0
117 INT341855 Positive_regulation of Positive_regulation of CDK2 1 0.06 0.51 0
118 INT302249 Positive_regulation of Phosphorylation of PSMD6 1 0.10 0.84 0
119 INT310440 Positive_regulation of POLA1 1 0.18 0.09 0
120 INT289620 Regulation of Binding of CDK2 1 0.28 0.22 0
121 INT186659 Regulation of Protein_catabolism of PSMB9 1 0.15 0.17 0
122 INT177818 Positive_regulation of PSMB6 1 0.19 0.25 0
123 INT214218 Negative_regulation of PSMD6 1 0.01 0 0
124 INT302251 Phosphorylation of PSMD6 1 0.17 0.84 0
125 INT155592 Positive_regulation of Binding of PSME1 1 0.09 0.1 0
126 INT280550 Regulation of Gene_expression of PSMB9 1 0.57 0.37 0
127 INT343564 Regulation of Gene_expression of PSMD6 1 0.44 0.35 0
128 INT287280 Positive_regulation of Negative_regulation of PSMD1 1 0.10 0 0
129 INT310439 Regulation of POLA1 1 0.24 2.21 0
130 INT310443 Negative_regulation of POLA1 1 0.16 0.31 0
131 INT166206 Regulation of Gene_expression of PSME1 1 0.19 0.28 0
132 INT175222 Binding of UBC 1 0.02 0.54 0
133 INT325169 Regulation of Negative_regulation of CDK2 1 0.34 0.05 0
134 INT209458 Negative_regulation of Gene_expression of PSMD2 1 0.23 0.2 0
135 INT261736 Gene_expression of PSMB6 1 0.01 0 0
136 INT225187 Positive_regulation of Binding of CDK2 1 0.56 0.87 0
137 INT186626 Protein_catabolism of PSMB6 1 0.16 0.17 0
138 INT219491 Negative_regulation of MCM3 1 0.14 0.36 0
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