GO:0000236

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Name mitotic prometaphase
Categary Process
Go Slim No
Go Link GO:0000236
Unique Molecular Interactions 103
Total Molecular Interactions 118
Total Single Events 756
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mitotic prometaphase. They are ordered first by their pain relevance and then by number of times they were reported for mitotic prometaphase. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT136200 Binding of Penk and NUP37 1 0.04 0 1.28
2 INT199976 EGF Regulation of ITGB3BP 1 0.02 0.77 0.57
3 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55
4 INT164264 TGM7 Negative_regulation of CCNB1 1 0.07 1.08 0.53
5 INT231340 INCENP Regulation of Gene_expression of IL6 1 0.01 1.09 0.47
6 INT177794 BUB1B Positive_regulation of Gene_expression of ASNS 1 0.11 0.77 0.46
7 INT177781 BUB1B Positive_regulation of ATF4 1 0.07 0.76 0.46
8 INT177780 BUB1B Positive_regulation of ASNS 1 0.05 0.76 0.46
9 INT177787 BUB1B Positive_regulation of MTHFD2 1 0.15 0.76 0.46
10 INT256321 INCENP Positive_regulation of Gene_expression of Vcam1 1 0.00 1.89 0.38
11 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38
12 INT299788 INCENP Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37
13 INT278749 NUP98 Positive_regulation of Gene_expression of PTGS2 1 0.46 1.28 0.35
14 INT226375 INCENP Positive_regulation of Regulation of TH1L 1 0.01 0.57 0.29
15 INT226376 INCENP Negative_regulation of Gene_expression of TH1L 1 0.00 0.61 0.29
16 INT226383 IL22 Positive_regulation of Gene_expression of INCENP 1 0.00 0.85 0.28
17 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28
18 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
19 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 0.01 0.72 0.26
20 INT252213 INCENP Regulation of Lgals3 1 0.00 1.91 0.23
21 INT183945 INCENP Positive_regulation of Localization of IL6 1 0.00 0.2 0.23
22 INT226384 INCENP Positive_regulation of IL19 1 0.00 0.58 0.2
23 INT265048 INCENP Positive_regulation of Positive_regulation of Nfasc 1 0.00 0.69 0.19
24 INT226372 INCENP Negative_regulation of Gene_expression of IL5 1 0.00 1.12 0.18
25 INT231866 INCENP Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18
26 INT262359 Binding of DISC1 and NDEL1 1 0.04 0.56 0.18
27 INT222443 INCENP Positive_regulation of Localization of Pomc 1 0.00 0.75 0.17
28 INT226367 INCENP Negative_regulation of SOCS1 1 0.01 0.47 0.15
29 INT343833 INCENP Positive_regulation of TLR4 1 0.01 0.92 0.14
30 INT343840 Protein_catabolism of INCENP Positive_regulation of TLR4 1 0.01 0.92 0.14
31 INT226378 INCENP Positive_regulation of Transcription of SOCS1 1 0.01 0.41 0.13
32 INT210161 INCENP Positive_regulation of TNFRSF8 1 0.02 0.93 0.12
33 INT235385 INCENP Negative_regulation of Bche 1 0.01 0.19 0.11
34 INT306274 Binding of CCNB1 and CDK1 1 0.19 0.13 0.09
35 INT222442 Tlr4 Positive_regulation of Gene_expression of INCENP 1 0.00 0.34 0.09
36 INT173058 INCENP Positive_regulation of Gene_expression of VEGFA 1 0.03 1.48 0.08
37 INT222662 Il1a Positive_regulation of Gene_expression of INCENP 1 0.00 0.32 0.08
38 INT257777 INCENP Positive_regulation of AR 1 0.04 0.49 0.08
39 INT186712 INCENP Positive_regulation of PPARA 1 0.01 1.05 0.08
40 INT294220 INCENP Positive_regulation of Gene_expression of Serpine1 1 0.00 0.41 0.08
41 INT294218 INCENP Positive_regulation of Plat 1 0.00 0.4 0.08
42 INT311432 Binding of TSHR and TAOK1 1 0.12 1.05 0.07
43 INT335711 INCENP Positive_regulation of Gene_expression of FAS 1 0.04 1.42 0.06
44 INT306510 INCENP Regulation of Gene_expression of Clu 1 0.00 1.92 0.05
45 INT327822 INCENP Regulation of Gene_expression of Lep 1 0.00 0.5 0.05
46 INT316489 Stat3 Positive_regulation of Transcription of Ccnb1 1 0.02 1.27 0.04
47 INT213392 Binding of SELPLG and XPO1 1 0.02 0.31 0.04
48 INT237206 LGALS4 Regulation of Gene_expression of Ccnb1 1 0.05 0 0.03
49 INT173612 FGFR1 Positive_regulation of INCENP 1 0.00 0.28 0.03
50 INT173613 BMP2 Positive_regulation of INCENP 1 0.00 0.28 0.03
51 INT318191 INCENP Negative_regulation of Gene_expression of VEGFA 1 0.00 1.05 0.03
52 INT300179 Binding of BGLAP and INCENP 1 0.02 0.08 0.03
53 INT183757 INCENP Negative_regulation of Transcription of CXCR4 1 0.01 0.93 0.03
54 INT318187 Binding of INCENP and MUC5AC 1 0.00 1.03 0.03
55 INT183758 INCENP Negative_regulation of Transcription of CCR5 1 0.00 0.93 0.03
56 INT231862 F2 Positive_regulation of INCENP 1 0.00 0.86 0.03
57 INT182397 NFYA Regulation of CCNB1 1 0.00 0.09 0
58 INT279515 Daf2 Negative_regulation of INCENP 1 0.00 0 0
59 INT343999 INCENP Positive_regulation of BMP2 1 0.01 0 0
60 INT278768 NUP98 Negative_regulation of Gene_expression of RAP1A 1 0.41 0.44 0
61 INT330697 PCNA Regulation of INCENP 1 0.00 0.3 0
62 INT225617 Binding of ITGB3BP and D0Nrs1 1 0.00 0.15 0
63 INT278772 NUP98 Regulation of HOXA9 1 0.42 0 0
64 INT278765 Binding of RUNX1 and NUP98 1 0.02 0.26 0
65 INT182402 E2F2 Regulation of CCNB1 1 0.00 0.09 0
66 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0
67 INT278755 OR51S1 Regulation of NUP98 1 0.00 0 0
68 INT171600 INCENP Negative_regulation of Lipg 1 0.00 0.38 0
69 INT239406 Binding of MTTP and TAOK1 1 0.02 0.51 0
70 INT213391 Positive_regulation of Binding of CHKB and XPO1 1 0.04 0.46 0
71 INT329101 Binding of CD4 and INCENP 1 0.01 0.11 0
72 INT222665 INCENP Positive_regulation of Localization of Gnrh1 1 0.00 0.09 0
73 INT171601 INCENP Negative_regulation of Lpl 1 0.01 0.38 0
74 INT278753 NUP98 Positive_regulation of KBTBD10 1 0.45 0 0
75 INT344001 INCENP Positive_regulation of Gene_expression of BMP2 1 0.01 0 0
76 INT278750 HOXA9 Regulation of NUP98 1 0.11 0 0
77 INT278752 Binding of NUP98 and HEY1 1 0.48 0 0
78 INT297124 Binding of INCENP and Hephl1 1 0.00 0.17 0
79 INT313653 INCENP Negative_regulation of PLA2G2D 1 0.01 0 0
80 INT278770 Binding of NUP98 and KBTBD10 1 0.35 0 0
81 INT135869 Binding of ICA1 and XPO1 1 0.18 0 0
82 INT278773 NUP98 Regulation of HEY1 1 0.45 0 0
83 INT66342 LIF Positive_regulation of Phosphorylation of CLIP1 1 0.60 1.57 0
84 INT220455 BAG6 Regulation of INCENP 1 0.00 0.32 0
85 INT278767 NUP98 Regulation of Gene_expression of HOXA9 1 0.42 0.23 0
86 INT209631 INCENP Negative_regulation of CHRM1 1 0.00 0.43 0
87 INT224993 INCENP Regulation of PDGFB 1 0.00 0 0
88 INT271997 Binding of Cdk1 and Plk1 1 0.03 0.3 0
89 INT239408 Binding of PADI1 and TAOK1 1 0.01 0.51 0
90 INT232055 Binding of XPO1 and RNPC3 1 0.02 0.3 0
91 INT249828 Foxm1 Positive_regulation of Transcription of BIRC5 1 0.56 0.12 0
92 INT255203 Binding of INCENP and Ie 1 0.00 0.77 0
93 INT232052 Binding of DDR1 and XPO1 1 0.01 0.3 0
94 INT278776 NUP98 Regulation of OR51S1 1 0.01 0 0
95 INT278759 Binding of HOXA9 and NUP98 1 0.34 0.06 0
96 INT257826 PAFAH1B1 Positive_regulation of Paf 1 0.02 1.02 0
97 INT279514 Cr1l Negative_regulation of INCENP 1 0.00 0 0
98 INT274622 Binding of CLIP1 and Amph 1 0.40 0 0
99 INT249822 Foxm1 Positive_regulation of Transcription of Plk1 1 0.50 0.12 0
100 INT278762 NUP98 Positive_regulation of PLN 1 0.47 0 0
101 INT274581 Binding of CLIP1 and BFAR 1 0.15 0 0
102 INT213394 Binding of CHKB and XPO1 1 0.03 0.46 0
103 INT209640 INCENP Negative_regulation of Gene_expression of CHRM1 1 0.00 0.91 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for mitotic prometaphase. They are ordered first by their pain relevance and then by number of times they were reported in mitotic prometaphase. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31
2 INT174838 Localization of INCENP 80 0.64 19.05 12.89
3 INT173639 Positive_regulation of INCENP 40 0.14 20.97 6.7
4 INT8101 Binding of INCENP 42 0.31 16.2 6.68
5 INT172551 Negative_regulation of INCENP 38 0.07 20.83 3.14
6 INT172177 Protein_catabolism of INCENP 18 0.37 6.34 2.91
7 INT222400 Negative_regulation of Localization of INCENP 4 0.02 1.82 2.46
8 INT173090 Regulation of INCENP 24 0.09 9.45 2.16
9 INT181280 Regulation of Gene_expression of INCENP 5 0.07 4 1.78
10 INT257820 Positive_regulation of PAFAH1B1 1 0.68 11.09 1.69
11 INT171975 Negative_regulation of Gene_expression of INCENP 8 0.05 5.24 1.35
12 INT173877 Positive_regulation of Gene_expression of INCENP 14 0.08 7.83 1.28
13 INT70138 Positive_regulation of Ccnb1 7 0.41 4.31 1.26
14 INT199979 Gene_expression of ITGB3BP 1 0.11 2.83 1.08
15 INT257824 Localization of PAFAH1B1 1 0.74 6.58 1
16 INT113841 Gene_expression of CCNB1 11 0.75 3.46 0.86
17 INT95190 Gene_expression of NDEL1 1 0.29 0 0.81
18 INT98784 Gene_expression of Ccnb1 11 0.59 4.53 0.75
19 INT180752 Gene_expression of PAFAH1B1 3 0.66 9.89 0.75
20 INT257817 Regulation of PAFAH1B1 1 0.60 4.93 0.7
21 INT181282 Transcription of INCENP 10 0.11 1.21 0.66
22 INT35943 Positive_regulation of NDEL1 1 0.31 0 0.62
23 INT257816 Negative_regulation of PAFAH1B1 1 0.58 3.66 0.49
24 INT35942 Negative_regulation of NDEL1 1 0.27 0 0.47
25 INT177869 Gene_expression of BUB1B 2 0.65 2.11 0.45
26 INT177866 Negative_regulation of BUB1B 1 0.32 1.23 0.45
27 INT177845 Negative_regulation of Gene_expression of BUB1B 1 0.23 0.75 0.45
28 INT353342 Positive_regulation of Positive_regulation of INCENP 1 0.01 0.46 0.4
29 INT95191 Protein_catabolism of NDEL1 1 0.22 0 0.39
30 INT199980 Negative_regulation of ITGB3BP 1 0.06 0.55 0.35
31 INT237161 Regulation of Ccnb1 5 0.17 2.71 0.32
32 INT222401 Regulation of Localization of INCENP 2 0.01 0.81 0.32
33 INT311448 Gene_expression of TAOK1 1 0.21 2.47 0.31
34 INT86771 Positive_regulation of TAOK1 2 0.38 4.55 0.29
35 INT184629 Negative_regulation of Positive_regulation of INCENP 1 0.05 0.89 0.28
36 INT226431 Phosphorylation of INCENP 3 0.04 3.41 0.26
37 INT1475 Localization of CLIP1 1 0.06 0 0.24
38 INT98783 Negative_regulation of Gene_expression of Ccnb1 1 0.26 0.69 0.21
39 INT199983 Negative_regulation of Gene_expression of ITGB3BP 1 0.08 0.75 0.21
40 INT311439 Positive_regulation of Gene_expression of TAOK1 1 0.15 1.48 0.18
41 INT262360 Binding of NDEL1 1 0.04 0.56 0.18
42 INT257825 Binding of PAFAH1B1 1 0.37 0.89 0.17
43 INT257818 Regulation of Gene_expression of PAFAH1B1 1 0.44 0.76 0.15
44 INT257821 Transcription of PAFAH1B1 1 0.61 1.11 0.14
45 INT185754 Negative_regulation of Binding of INCENP 5 0.03 2.01 0.13
46 INT277821 Positive_regulation of Negative_regulation of INCENP 2 0.03 0.89 0.12
47 INT42713 Binding of CLIP1 2 0.36 0 0.1
48 INT46301 Positive_regulation of CLIP1 2 0.60 0 0.1
49 INT199981 Regulation of ITGB3BP 1 0.04 0.5 0.1
50 INT306284 Binding of CCNB1 1 0.28 0.13 0.09
51 INT240093 Negative_regulation of Transcription of INCENP 1 0.01 0.26 0.09
52 INT221970 Phosphorylation of NDEL1 1 0.12 0.39 0.09
53 INT213406 Positive_regulation of XPO1 5 0.27 1.19 0.08
54 INT226414 Negative_regulation of Ccnb1 2 0.02 2.16 0.08
55 INT238499 Negative_regulation of BIRC5 1 0.23 1.66 0.08
56 INT278803 Gene_expression of NUP98 1 0.72 0.78 0.08
57 INT113842 Negative_regulation of CCNB1 1 0.40 0.53 0.06
58 INT66352 Phosphorylation of CLIP1 2 0.63 0.88 0.05
59 INT311444 Binding of TAOK1 1 0.11 0.65 0.05
60 INT213405 Regulation of XPO1 1 0.17 0.87 0.05
61 INT278784 Regulation of Gene_expression of NUP98 1 0.42 0 0.04
62 INT316438 Transcription of Ccnb1 1 0.02 1.24 0.04
63 INT208224 Protein_catabolism of TAOK1 1 0.05 0.94 0.04
64 INT332373 Binding of Ccnb1 1 0.34 0 0.03
65 INT278793 Phosphorylation of NUP98 1 0.76 0 0.03
66 INT329787 Regulation of CCNB1 1 0.08 1.21 0.03
67 INT199985 Positive_regulation of Gene_expression of ITGB3BP 1 0.06 0 0.03
68 INT237226 Gene_expression of Plk1 3 0.59 0.78 0
69 INT124651 Gene_expression of XPO1 2 0.30 0.64 0
70 INT249788 Positive_regulation of Gene_expression of Ccnb1 2 0.44 0.51 0
71 INT249774 Positive_regulation of Plk1 2 0.41 0.25 0
72 INT230109 Positive_regulation of Gene_expression of BUB1B 1 0.42 0.65 0
73 INT289873 Negative_regulation of Gene_expression of CCNB1 1 0.15 0 0
74 INT181285 Positive_regulation of Transcription of INCENP 1 0.08 0 0
75 INT249820 Transcription of BIRC5 1 0.67 0.12 0
76 INT249818 Gene_expression of BIRC5 1 0.65 0.12 0
77 INT271928 Binding of Plk1 1 0.07 0.29 0
78 INT278797 Binding of NUP98 1 0.35 0.3 0
79 INT332370 Regulation of Plk1 1 0.21 0.13 0
80 INT278801 Positive_regulation of NUP98 1 0.47 0 0
81 INT289864 Positive_regulation of CCNB1 1 0.25 0 0
82 INT278789 Regulation of Localization of NUP98 1 0.42 0 0
83 INT278800 Localization of NUP98 1 0.70 0 0
84 INT289859 Localization of CCNB1 1 0.24 0.27 0
85 INT332346 Phosphorylation of Plk1 1 0.62 0 0
86 INT278796 Regulation of NUP98 1 0.25 0 0
87 INT249761 Transcription of Plk1 1 0.60 0.12 0
88 INT249819 Positive_regulation of Gene_expression of BIRC5 1 0.49 0.12 0
89 INT337117 Gene_expression of CLIP1 1 0.13 0.08 0
90 INT289860 Negative_regulation of Positive_regulation of CCNB1 1 0.15 0 0
91 INT249770 Positive_regulation of Gene_expression of Plk1 1 0.44 0.12 0
92 INT66349 Positive_regulation of Phosphorylation of CLIP1 1 0.36 0.78 0
93 INT289871 Positive_regulation of Gene_expression of CCNB1 1 0.25 0.41 0
94 INT256925 Protein_catabolism of Ccnb1 1 0.24 0.74 0
95 INT213396 Regulation of Gene_expression of XPO1 1 0.15 0 0
96 INT322739 Localization of TAOK1 1 0.02 1.24 0
97 INT332343 Positive_regulation of Phosphorylation of Plk1 1 0.38 0 0
98 INT256906 Regulation of Gene_expression of Ccnb1 1 0.17 0.39 0
99 INT331145 Phosphorylation of Ccnb1 1 0.17 0.58 0
100 INT249821 Positive_regulation of BIRC5 1 0.45 0.12 0
101 INT271923 Regulation of Binding of Plk1 1 0.09 0.29 0
102 INT237227 Negative_regulation of Gene_expression of Plk1 1 0.08 0.54 0
103 INT175536 Positive_regulation of Localization of INCENP 1 0.01 0.59 0
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