GO:0000266

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Name mitochondrial fission
Categary Process
Go Slim No
Go Link GO:0000266
Unique Molecular Interactions 37
Total Molecular Interactions 47
Total Single Events 213
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mitochondrial fission. They are ordered first by their pain relevance and then by number of times they were reported for mitochondrial fission. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117504 OPA1 Positive_regulation of CPP 1 0.09 1.09 1.13
2 INT157142 OPA1 Positive_regulation of Gene_expression of Camk2a 1 0.02 0.3 1.02
3 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 2 0.03 0.24 0.65
4 INT134080 OPA1 Negative_regulation of Phosphorylation of Gnb2l1 1 0.03 0.22 0.34
5 INT161435 OPA1 Positive_regulation of Gene_expression of Tnc 1 0.02 0.21 0.32
6 INT334267 Mul1 Positive_regulation of Protein_catabolism of Tlr4 1 0.01 0.18 0.18
7 INT302676 Binding of OPA1 and MFN2 1 0.46 1.12 0.14
8 INT302511 Binding of OPA1 and Nos3 1 0.02 1.57 0.1
9 INT226210 Akt1 Regulation of Mul1 1 0.04 0.6 0.1
10 INT191432 Binding of COX10 and EDIL3 1 0.01 1.79 0.1
11 INT50286 OPA1 Positive_regulation of cod 1 0.01 0.16 0.08
12 INT283721 Binding of Lpin1 and Id2 1 0.38 0.18 0.08
13 INT41172 OPA1 Positive_regulation of RTCA 1 0.18 0.16 0.07
14 INT217472 Binding of Nup62 and Mul1 1 0.12 0 0.05
15 INT217468 Positive_regulation of Binding of Nup62 and Mul1 1 0.16 0 0.05
16 INT300449 VEGFA Positive_regulation of Protein_catabolism of Ppp2r2b 1 0.00 1.51 0.05
17 INT274095 Binding of EDNRA and OPA1 1 0.12 0.65 0.04
18 INT239438 Binding of OPA1 and LIPG 1 0.03 1.21 0.04
19 INT283715 Lpin1 Regulation of 4930579C15Rik 1 0.35 0.74 0
20 INT155996 OPA1 Positive_regulation of Transcription of Calcb 1 0.02 0 0
21 INT298688 Binding of OPA1 and MFN1 1 0.52 2.09 0
22 INT302507 Binding of GLC1F and OPA1 1 0.01 3.76 0
23 INT298687 Binding of OPA1 and PARL 1 0.50 2.09 0
24 INT303394 Binding of Myh3 and Mul1 1 0.04 0.38 0
25 INT155997 OPA1 Positive_regulation of Gene_expression of Calca 1 0.12 0 0
26 INT245821 Binding of Ppp2r2b and Ocln 1 0.00 0.81 0
27 INT317302 Binding of Park2 and Mul1 1 0.01 0.62 0
28 INT211570 Kit Regulation of Gene_expression of Lpin1 1 0.27 0.12 0
29 INT302675 Binding of OPA1 and PLAA 1 0.15 0.73 0
30 INT273885 Binding of Mul1 and Cul2 1 0.06 0 0
31 INT303392 Mul1 Positive_regulation of Protein_catabolism of Myh3 1 0.06 0 0
32 INT211577 Vldlr Regulation of Gene_expression of Lpin1 1 0.27 0.12 0
33 INT155998 OPA1 Positive_regulation of Transcription of Calca 1 0.13 0 0
34 INT303385 Mul1 Positive_regulation of Protein_catabolism of Gopc 1 0.03 0 0
35 INT317308 Binding of Park7 and Mul1 1 0.01 0.62 0
36 INT317306 Binding of Mul1 and Pink1 1 0.01 0.62 0
37 INT333031 Binding of Itch and Mul1 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for mitochondrial fission. They are ordered first by their pain relevance and then by number of times they were reported in mitochondrial fission. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45
2 INT33854 Localization of OPA1 19 0.65 10.55 5.04
3 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5
4 INT24883 Regulation of OPA1 14 0.45 9.73 3.44
5 INT5913 Binding of OPA1 12 0.41 9.33 2.92
6 INT3605 Negative_regulation of OPA1 14 0.38 10.88 2.84
7 INT211548 Gene_expression of Lpin1 9 0.76 12.83 0.96
8 INT149394 Positive_regulation of Mul1 4 0.12 1.89 0.53
9 INT158456 Positive_regulation of Localization of OPA1 1 0.43 0.34 0.43
10 INT34976 Positive_regulation of Gene_expression of OPA1 4 0.43 4.21 0.4
11 INT231102 Gene_expression of Mul1 8 0.21 1.66 0.35
12 INT134079 Phosphorylation of OPA1 1 0.16 0.22 0.33
13 INT161434 Regulation of Negative_regulation of OPA1 1 0.03 0.2 0.32
14 INT283693 Transcription of Lpin1 1 0.67 1.31 0.22
15 INT231095 Positive_regulation of Gene_expression of Mul1 1 0.13 0.82 0.19
16 INT55496 Phosphorylation of Ppp2r2b 1 0.23 0 0.16
17 INT55497 Negative_regulation of Phosphorylation of Ppp2r2b 1 0.16 0 0.16
18 INT55499 Localization of Ppp2r2b 1 0.26 0 0.15
19 INT55498 Negative_regulation of Ppp2r2b 1 0.16 0 0.15
20 INT245803 Protein_catabolism of Ppp2r2b 2 0.02 3.02 0.13
21 INT111656 Regulation of Mul1 1 0.02 0.08 0.13
22 INT211536 Binding of Lpin1 2 0.46 1.06 0.12
23 INT273866 Binding of Mul1 4 0.11 0.69 0.09
24 INT175415 Negative_regulation of COX10 5 0.07 3.33 0.08
25 INT231099 Regulation of Gene_expression of Mul1 1 0.12 0.08 0.07
26 INT231090 Negative_regulation of Gene_expression of Mul1 1 0.11 0.08 0.07
27 INT283679 Positive_regulation of Lpin1 1 0.48 0.57 0.07
28 INT283677 Localization of Lpin1 1 0.32 0.37 0.05
29 INT300432 Negative_regulation of Protein_catabolism of Ppp2r2b 1 0.01 1.52 0.05
30 INT211538 Negative_regulation of Lpin1 1 0.57 1.28 0.04
31 INT223610 Binding of COX10 1 0.05 0.46 0
32 INT302688 Transcription of OPA1 1 0.68 0.3 0
33 INT300435 Gene_expression of Ppp2r2b 1 0.02 0.56 0
34 INT211543 Regulation of Lpin1 1 0.60 0.28 0
35 INT82782 Negative_regulation of Regulation of OPA1 1 0.05 0 0
36 INT317277 Negative_regulation of Mul1 1 0.01 0.68 0
37 INT300434 Positive_regulation of Ppp2r2b 1 0.01 0.67 0
38 INT223595 Negative_regulation of Binding of COX10 1 0.05 0.47 0
39 INT211562 Positive_regulation of Gene_expression of Lpin1 1 0.49 0.27 0
40 INT211545 Negative_regulation of Gene_expression of Lpin1 1 0.42 0.38 0
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