GO:0000267

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Name cell fraction
Categary Component
Go Slim No
Go Link GO:0000267
Unique Molecular Interactions 25
Total Molecular Interactions 32
Total Single Events 413
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell fraction. They are ordered first by their pain relevance and then by number of times they were reported for cell fraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149925 Negative_regulation of Cpox Negative_regulation of Gene_expression of Pde4d 1 0.01 0.39 0.84
2 INT84603 Adrb1 Regulation of Gene_expression of Aqp2 1 0.00 0 0.56
3 INT273350 Pde7a Positive_regulation of Localization of Pde4d 1 0.33 1.35 0.49
4 INT84600 Binding of Avp and Aqp2 1 0.17 0 0.35
5 INT293118 Avp Regulation of Aqp2 1 0.04 0.7 0.27
6 INT219597 Prkaca Positive_regulation of Pde4d 1 0.29 0 0.15
7 INT263178 Binding of PDE7A and COPD 1 0.01 1 0.15
8 INT263174 PDE7A Regulation of COPD 1 0.01 1 0.15
9 INT293124 Agtr1a Regulation of Gene_expression of Aqp2 1 0.17 0.36 0.14
10 INT293117 Agt Regulation of Gene_expression of Aqp2 1 0.23 0.36 0.14
11 INT219599 Pde4d Regulation of Prkaca 1 0.28 0 0.12
12 INT204877 gr Negative_regulation of Serpina3n 1 0.23 0.15 0.1
13 INT263173 Binding of PDE7A and Prkaca 1 0.01 0.27 0.09
14 INT219600 Pde4d Regulation of Binding of Prkaca 1 0.28 0 0.09
15 INT219602 Binding of Prkaca and Pde4d 1 0.23 0 0.09
16 INT234802 Binding of AQP2 and AVPR2 2 0.15 0.84 0.07
17 INT273353 Pde4d Regulation of Gene_expression of Twist1 1 0.26 0.25 0.05
18 INT293122 Avp Regulation of Gene_expression of Aqp2 1 0.04 0.81 0.05
19 INT241775 AVP Positive_regulation of Gene_expression of AQP2 1 0.08 0.17 0
20 INT297693 Binding of Aqp2 and Fut1 1 0.03 0 0
21 INT219596 Binding of Pde4a and Pde4d 1 0.28 0.31 0
22 INT354080 Avpr2 Positive_regulation of Localization of Aqp2 1 0.02 0.07 0
23 INT293114 Fig4 Regulation of Gene_expression of Aqp2 1 0.08 1.53 0
24 INT234803 AVP Regulation of AQP2 1 0.11 1.3 0
25 INT234796 Binding of AQP2 and AVP 1 0.15 1.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell fraction. They are ordered first by their pain relevance and then by number of times they were reported in cell fraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104569 Gene_expression of Aqp2 23 0.60 16.56 12.23
2 INT327801 Positive_regulation of Gene_expression of Aqp2 6 0.44 7.67 7.24
3 INT105775 Gene_expression of Pde4d 31 0.78 4.18 5.21
4 INT84599 Gene_expression of Aqp2 31 0.77 22.58 2.54
5 INT79399 Gene_expression of Pde4d 6 0.70 2.83 2.51
6 INT107489 Negative_regulation of Pde4d 3 0.42 0 2.47
7 INT263127 Negative_regulation of PDE7A 13 0.27 8.03 2.13
8 INT107490 Positive_regulation of Pde4d 3 0.69 0.07 2.13
9 INT105776 Negative_regulation of Gene_expression of Pde4d 5 0.59 2.2 2.01
10 INT84595 Negative_regulation of Aqp2 11 0.58 4.88 1.78
11 INT156133 Regulation of Gene_expression of Aqp2 4 0.39 1.43 1.53
12 INT135924 Positive_regulation of Gene_expression of Pde4d 2 0.59 0 1.28
13 INT105908 Gene_expression of PDE7A 21 0.78 4.49 1.26
14 INT149924 Negative_regulation of Gene_expression of Pde4d 1 0.26 0.81 1.24
15 INT100328 Gene_expression of AQP2 6 0.75 2.41 1.21
16 INT79557 Localization of Aqp2 5 0.73 2 1.13
17 INT219589 Binding of Pde4d 13 0.47 0.51 1.01
18 INT219568 Positive_regulation of Pde4d 9 0.49 1.74 1
19 INT84597 Transcription of Aqp2 3 0.55 2.11 0.98
20 INT84598 Regulation of Aqp2 13 0.45 4.28 0.86
21 INT108348 Positive_regulation of Aqp2 10 0.68 4.94 0.82
22 INT219578 Negative_regulation of Pde4d 3 0.46 2.95 0.8
23 INT135923 Regulation of Gene_expression of Pde4d 2 0.44 0 0.8
24 INT118753 Regulation of Negative_regulation of Pde4d 1 0.02 0 0.8
25 INT149238 Positive_regulation of Gene_expression of Aqp2 5 0.66 3.07 0.73
26 INT327798 Transcription of Aqp2 1 0.34 1.02 0.72
27 INT241788 Positive_regulation of Gene_expression of AQP2 3 0.67 1.26 0.7
28 INT112326 Binding of Aqp2 3 0.11 1.01 0.69
29 INT219580 Localization of Pde4d 5 0.73 2.07 0.64
30 INT84596 Negative_regulation of Gene_expression of Aqp2 3 0.58 8.49 0.6
31 INT84594 Negative_regulation of Transcription of Aqp2 1 0.43 0 0.59
32 INT100322 Localization of AQP2 5 0.80 0.56 0.56
33 INT79397 Positive_regulation of Gene_expression of Pde4d 1 0.45 0.2 0.55
34 INT219573 Positive_regulation of Localization of Pde4d 2 0.49 1.39 0.5
35 INT149235 Positive_regulation of Transcription of Aqp2 1 0.45 0.72 0.4
36 INT149244 Positive_regulation of Localization of Aqp2 1 0.49 0.72 0.4
37 INT105906 Transcription of PDE7A 8 0.72 1.21 0.39
38 INT219565 Regulation of Pde4d 3 0.44 0.5 0.39
39 INT275542 Regulation of Gene_expression of PDE7A 1 0.12 1.98 0.39
40 INT275538 Regulation of PDE7A 1 0.12 1.97 0.39
41 INT100324 Regulation of Localization of AQP2 1 0.27 0.19 0.38
42 INT157836 Regulation of Gene_expression of Aqp2 9 0.57 8.37 0.37
43 INT100323 Regulation of Gene_expression of AQP2 1 0.45 0.18 0.36
44 INT273330 Positive_regulation of Negative_regulation of Pde4d 1 0.39 1.25 0.35
45 INT12169 Gene_expression of Serpina3n 2 0.48 3.44 0.34
46 INT79558 Binding of Aqp2 2 0.31 0.25 0.33
47 INT273341 Transcription of Pde4d 2 0.54 0.68 0.24
48 INT263139 Positive_regulation of Negative_regulation of PDE7A 1 0.23 0.65 0.24
49 INT273336 Regulation of Negative_regulation of Pde4d 1 0.35 0.68 0.24
50 INT263125 Regulation of Negative_regulation of PDE7A 1 0.28 0.72 0.21
51 INT263133 Positive_regulation of Gene_expression of PDE7A 2 0.21 0.56 0.19
52 INT105907 Positive_regulation of Transcription of PDE7A 4 0.47 0.53 0.16
53 INT219593 Regulation of Binding of Pde4d 1 0.44 0 0.13
54 INT173720 Regulation of Serpina3n 1 0.14 0.52 0.13
55 INT104566 Negative_regulation of Aqp2 3 0.44 1.23 0.11
56 INT263122 Binding of PDE7A 1 0.22 0.27 0.1
57 INT219574 Phosphorylation of Pde4d 1 0.79 0.33 0.1
58 INT111047 Negative_regulation of Gene_expression of Aqp2 3 0.34 3.56 0.09
59 INT157832 Phosphorylation of Aqp2 2 0.77 2.04 0.08
60 INT219585 Positive_regulation of Positive_regulation of Pde4d 1 0.43 0 0.06
61 INT293110 Positive_regulation of Phosphorylation of Aqp2 1 0.47 1.39 0.05
62 INT204876 Localization of Serpina3n 1 0.73 0.09 0.04
63 INT293105 Positive_regulation of Positive_regulation of Aqp2 1 0.47 0.72 0.03
64 INT241787 Negative_regulation of AQP2 1 0.57 1.38 0.03
65 INT280794 Localization of Aqp2 2 0.36 0.07 0
66 INT248265 Regulation of Pde4d 1 0.21 0.87 0
67 INT157833 Negative_regulation of Negative_regulation of Aqp2 1 0.36 0 0
68 INT280786 Phosphorylation of Aqp2 1 0.32 0.24 0
69 INT297668 Positive_regulation of Aqp2 1 0.45 0 0
70 INT108349 Regulation of AQP2 1 0.44 0 0
71 INT263141 Regulation of Localization of PDE7A 1 0.21 0 0
72 INT100325 Positive_regulation of AQP2 1 0.69 0 0
73 INT341042 Positive_regulation of Protein_catabolism of Aqp2 1 0.34 0.07 0
74 INT219570 Negative_regulation of Positive_regulation of Pde4d 1 0.42 0 0
75 INT100326 Positive_regulation of Localization of AQP2 1 0.69 0 0
76 INT341039 Protein_catabolism of Aqp2 1 0.47 0.06 0
77 INT219575 Positive_regulation of Binding of Pde4d 1 0.49 0 0
78 INT100327 Regulation of Positive_regulation of AQP2 1 0.39 0 0
79 INT263140 Localization of PDE7A 1 0.35 0 0
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