GO:0000278

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Name mitotic cell cycle
Categary Process
Go Slim No
Go Link GO:0000278
Unique Molecular Interactions 506
Total Molecular Interactions 680
Total Single Events 4902
Pain Genes Associated 77

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
2 INT73116 TYMS Negative_regulation of DNMT3B 1 0.24 0 1.6
3 INT73115 TYMS Negative_regulation of Positive_regulation of DNMT3B 1 0.24 0 1.6
4 INT136200 Binding of Penk and NUP37 1 0.04 0 1.28
5 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
6 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
7 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
8 INT79602 Binding of PSMA5 and Oprd1 2 0.19 1.05 1.01
9 INT306823 Binding of E2F4 and GOPC 1 0.06 0.23 0.91
10 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
11 INT116107 CDK4 Positive_regulation of Phosphorylation of EID1 1 0.01 0.32 0.86
12 INT306831 Positive_regulation of Binding of E2F4 and NOLC1 1 0.10 0.46 0.85
13 INT306826 Binding of E2F4 and NOLC1 1 0.08 0.41 0.84
14 INT258798 Binding of NR3C1 and HSP90AA1 1 0.01 1.09 0.78
15 INT144286 ACP1 Negative_regulation of Phosphorylation of PSMC6 1 0.45 0.39 0.78
16 INT251729 Binding of FEN1 and EXOSC1 1 0.19 1.13 0.74
17 INT72229 Binding of NFKBIL1 and BTRC 1 0.00 0 0.73
18 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
19 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
20 INT166395 CDKN1A Regulation of Gene_expression of IFI27 1 0.32 0.83 0.61
21 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
22 INT166392 IFI27 Regulation of Gene_expression of CDKN1A 1 0.32 0.83 0.61
23 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
24 INT92996 Binding of VCAM1 and GORASP1 1 0.39 0.33 0.6
25 INT199976 EGF Regulation of ITGB3BP 1 0.02 0.77 0.57
26 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55
27 INT164265 TGM7 Negative_regulation of CDK2 1 0.26 1.08 0.53
28 INT164264 TGM7 Negative_regulation of CCNB1 1 0.07 1.08 0.53
29 INT164262 TGM7 Negative_regulation of E2F1 1 0.16 1.08 0.53
30 INT177504 Gabrg1 Positive_regulation of PCNA 1 0.07 0.22 0.52
31 INT72230 Binding of BTRC and EMID1 1 0.00 0 0.49
32 INT72227 Binding of BTRC and AP1M2 1 0.00 0 0.49
33 INT58578 Binding of RPA1 and TACR1 1 0.01 0 0.48
34 INT231340 INCENP Regulation of Gene_expression of IL6 1 0.01 1.09 0.47
35 INT177794 BUB1B Positive_regulation of Gene_expression of ASNS 1 0.11 0.77 0.46
36 INT306828 Binding of E2F2 and E2F3 1 0.20 0.15 0.46
37 INT306824 Binding of E2F1 and E2F2 1 0.15 0.15 0.46
38 INT177781 BUB1B Positive_regulation of ATF4 1 0.07 0.76 0.46
39 INT177780 BUB1B Positive_regulation of ASNS 1 0.05 0.76 0.46
40 INT177787 BUB1B Positive_regulation of MTHFD2 1 0.15 0.76 0.46
41 INT13879 Binding of PSMB9 and KCNAB2 1 0.03 0.19 0.41
42 INT158032 Binding of CDKN2A and KRT20 1 0.28 0.59 0.4
43 INT162289 Binding of TUBA1A and Phospho2 1 0.31 1.26 0.4
44 INT162288 Regulation of Binding of TUBA1A and Phospho2 1 0.24 1.28 0.4
45 INT7636 RFC1 Negative_regulation of Localization of Oxt 1 0.14 0 0.39
46 INT13715 PDYN Positive_regulation of TYMS 1 0.27 0 0.39
47 INT7634 RFC1 Negative_regulation of Localization of AVP 1 0.46 0 0.39
48 INT256321 INCENP Positive_regulation of Gene_expression of Vcam1 1 0.00 1.89 0.38
49 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
50 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38
51 INT241614 CCNA2 Regulation of PRB3 1 0.06 0 0.37
52 INT299788 INCENP Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37
53 INT306830 E2F2 Regulation of C1orf61 1 0.02 0.48 0.36
54 INT278749 NUP98 Positive_regulation of Gene_expression of PTGS2 1 0.46 1.28 0.35
55 INT306822 Binding of E2F2 and GOPC 1 0.05 0.53 0.35
56 INT204071 HP Positive_regulation of Gene_expression of CDKN2A 1 0.00 3.48 0.34
57 INT119262 PPM1E Negative_regulation of Positive_regulation of CDKN1A 1 0.01 0.96 0.33
58 INT304277 CCNE1 Positive_regulation of IL1RN 1 0.00 1.93 0.31
59 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
60 INT166391 IFI27 Regulation of Gene_expression of CDKN1B 1 0.33 0.41 0.31
61 INT304278 CCNE1 Positive_regulation of IL8 1 0.02 1.93 0.31
62 INT304280 CCNE1 Positive_regulation of IL6 1 0.00 1.93 0.31
63 INT166397 CDKN1B Regulation of Gene_expression of IFI27 1 0.33 0.41 0.31
64 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
65 INT226375 INCENP Positive_regulation of Regulation of TH1L 1 0.01 0.57 0.29
66 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29
67 INT226376 INCENP Negative_regulation of Gene_expression of TH1L 1 0.00 0.61 0.29
68 INT226383 IL22 Positive_regulation of Gene_expression of INCENP 1 0.00 0.85 0.28
69 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28
70 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
71 INT147593 Binding of CDK4 and CDKN2A 1 0.42 0.23 0.26
72 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 0.01 0.72 0.26
73 INT147592 Positive_regulation of Binding of CDK4 and CDKN2A 1 0.44 0.23 0.26
74 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
75 INT317773 Positive_regulation of GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
76 INT317775 GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
77 INT35178 Binding of STT3A and PSME3 1 0.01 0.38 0.25
78 INT317771 GSR Positive_regulation of HDAC1 1 0.10 0.69 0.25
79 INT317776 Positive_regulation of GSR Positive_regulation of HDAC1 1 0.10 0.69 0.25
80 INT72231 Negative_regulation of Binding of NFKBIL1 and BTRC 1 0.00 0 0.24
81 INT333892 TNF Positive_regulation of Gene_expression of HDAC1 1 0.09 0.46 0.23
82 INT252213 INCENP Regulation of Lgals3 1 0.00 1.91 0.23
83 INT183945 INCENP Positive_regulation of Localization of IL6 1 0.00 0.2 0.23
84 INT264517 PTGDS Positive_regulation of TFDP1 1 0.17 0.5 0.22
85 INT264519 PTGDS Negative_regulation of Positive_regulation of TFDP1 1 0.15 0.5 0.22
86 INT78349 Binding of GALR1 and TUBB 1 0.39 0 0.21
87 INT322017 RPA1 Positive_regulation of IL1B 1 0.00 0 0.21
88 INT226384 INCENP Positive_regulation of IL19 1 0.00 0.58 0.2
89 INT265048 INCENP Positive_regulation of Positive_regulation of Nfasc 1 0.00 0.69 0.19
90 INT212084 NOXO1 Positive_regulation of CDKN1A 1 0.06 0.53 0.19
91 INT91862 RPA1 Negative_regulation of Transcription of ATG9B 1 0.03 0.46 0.19
92 INT226372 INCENP Negative_regulation of Gene_expression of IL5 1 0.00 1.12 0.18
93 INT58579 Binding of INSRR and RPA1 1 0.00 0 0.18
94 INT231866 INCENP Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18
95 INT262359 Binding of DISC1 and NDEL1 1 0.04 0.56 0.18
96 INT222443 INCENP Positive_regulation of Localization of Pomc 1 0.00 0.75 0.17
97 INT355829 Binding of SETBP1 and LIN9 1 0.00 0.06 0.17
98 INT119264 Binding of RB1 and PPM1E 1 0.00 0.46 0.17
99 INT119263 Binding of CDKN1A and PPM1E 1 0.01 0.46 0.17
100 INT47965 Binding of TF and GORASP1 1 0.52 0.35 0.16
101 INT180503 Binding of SARS and PSMD6 1 0.22 2.44 0.16
102 INT47967 Binding of EVI2B and GORASP1 1 0.03 0.35 0.16
103 INT226367 INCENP Negative_regulation of SOCS1 1 0.01 0.47 0.15
104 INT269330 DYNC1I2 Negative_regulation of PRKCA 1 0.03 0 0.15
105 INT269325 DYNC1I2 Positive_regulation of TMPO 1 0.01 0 0.15
106 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14
107 INT123192 Bmp6 Positive_regulation of CDKN1A 1 0.18 0.61 0.14
108 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14
109 INT343833 INCENP Positive_regulation of TLR4 1 0.01 0.92 0.14
110 INT343840 Protein_catabolism of INCENP Positive_regulation of TLR4 1 0.01 0.92 0.14
111 INT88410 BMP7 Negative_regulation of CDK2 1 0.35 0 0.14
112 INT252902 PTTG1 Regulation of MMP2 1 0.01 1.5 0.14
113 INT193789 SDF2L1 Positive_regulation of CDKN1A 1 0.00 0.68 0.13
114 INT253009 Igf1 Regulation of PTTG1 1 0.03 0.44 0.13
115 INT184953 Binding of CDC6 and PCNA 1 0.05 0.19 0.13
116 INT226378 INCENP Positive_regulation of Transcription of SOCS1 1 0.01 0.41 0.13
117 INT253015 Egf Regulation of PTTG1 1 0.02 0.44 0.13
118 INT193785 SDF2L1 Positive_regulation of Gene_expression of CDKN1A 1 0.00 0.68 0.13
119 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13
120 INT302156 AKT1 Positive_regulation of E2F2 1 0.02 0.88 0.13
121 INT210161 INCENP Positive_regulation of TNFRSF8 1 0.02 0.93 0.12
122 INT235385 INCENP Negative_regulation of Bche 1 0.01 0.19 0.11
123 INT42154 NPPA Regulation of Gene_expression of TUBA4A 1 0.04 0.68 0.1
124 INT57014 PSMB1 Regulation of SCN5A 1 0.02 0 0.1
125 INT42153 NPPA Regulation of TUBA4A 1 0.04 0.68 0.1
126 INT306274 Binding of CCNB1 and CDK1 1 0.19 0.13 0.09
127 INT57220 Positive_regulation of ATF3 Positive_regulation of PRKACA 1 0.17 0.1 0.09
128 INT222442 Tlr4 Positive_regulation of Gene_expression of INCENP 1 0.00 0.34 0.09
129 INT233858 CHKA Positive_regulation of Gene_expression of CDKN1B 1 0.10 0.17 0.09
130 INT57214 ATF3 Positive_regulation of PRKACA 1 0.17 0.1 0.09
131 INT230857 Negative_regulation of Binding of HSP90AA1 and NOS1 1 0.05 1.18 0.09
132 INT230856 Binding of HSP90AA1 and NOS1 1 0.04 1.17 0.09
133 INT185279 Binding of CCND1 and CDK4 4 0.13 2.05 0.08
134 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08
135 INT238392 RB1 Regulation of E2F2 1 0.01 0.36 0.08
136 INT298351 PSMD1 Regulation of Gene_expression of HLA-DRA 1 0.01 0.42 0.08
137 INT237922 TNFSF10 Positive_regulation of CDKN1A 1 0.09 3.28 0.08
138 INT302178 CDKN1C Regulation of CDKN2A 1 0.09 0.26 0.08
139 INT173058 INCENP Positive_regulation of Gene_expression of VEGFA 1 0.03 1.48 0.08
140 INT238397 EID1 Regulation of E2F2 1 0.00 0.36 0.08
141 INT166785 NSMAF Negative_regulation of Gene_expression of PCNA 1 0.30 1.26 0.08
142 INT302158 CDKN1A Regulation of CDKN2A 1 0.04 0.26 0.08
143 INT222662 Il1a Positive_regulation of Gene_expression of INCENP 1 0.00 0.32 0.08
144 INT257777 INCENP Positive_regulation of AR 1 0.04 0.49 0.08
145 INT186712 INCENP Positive_regulation of PPARA 1 0.01 1.05 0.08
146 INT302139 LAMTOR1 Regulation of CDKN2A 1 0.08 0.26 0.08
147 INT302157 MRPL28 Regulation of CDKN2A 1 0.09 0.26 0.08
148 INT298356 PSMD1 Regulation of Gene_expression of Cd14 1 0.04 0.42 0.08
149 INT320267 CCNA2 Positive_regulation of CDK1 1 0.12 1.08 0.08
150 INT245118 RBM45 Negative_regulation of CDKN2B 1 0.01 1.41 0.08
151 INT166784 Binding of PSMD1 and Nkx6-2 1 0.21 0.5 0.08
152 INT294220 INCENP Positive_regulation of Gene_expression of Serpine1 1 0.00 0.41 0.08
153 INT294218 INCENP Positive_regulation of Plat 1 0.00 0.4 0.08
154 INT302148 IFI27 Regulation of CDKN2A 1 0.11 0.26 0.08
155 INT245119 Negative_regulation of RBM45 Negative_regulation of CDKN2B 1 0.01 1.43 0.08
156 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07
157 INT88411 Positive_regulation of PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
158 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07
159 INT193783 ITIH4 Regulation of Gene_expression of CDKN1A 1 0.03 0.55 0.07
160 INT311432 Binding of TSHR and TAOK1 1 0.12 1.05 0.07
161 INT119268 CDKN1A Regulation of CREBBP 1 0.21 0.44 0.07
162 INT88408 PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
163 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07
164 INT107727 ASIP Negative_regulation of RRM2 1 0.29 0.43 0.07
165 INT302160 LAMTOR1 Regulation of CDKN1A 1 0.08 0.26 0.06
166 INT302150 MRPL28 Regulation of CDKN1B 1 0.09 0.26 0.06
167 INT308831 Binding of RFC1 and IGKV2D-29 1 0.02 0 0.06
168 INT302136 LAMTOR1 Regulation of CDKN1B 1 0.08 0.26 0.06
169 INT302127 MRPL28 Regulation of CDKN1A 1 0.09 0.26 0.06
170 INT335711 INCENP Positive_regulation of Gene_expression of FAS 1 0.04 1.42 0.06
171 INT306510 INCENP Regulation of Gene_expression of Clu 1 0.00 1.92 0.05
172 INT302133 IFI27 Regulation of CDKN1B 1 0.11 0.26 0.05
173 INT302130 CDKN1A Regulation of CDKN1B 1 0.04 0.26 0.05
174 INT302176 CDKN1C Regulation of CDKN1A 1 0.09 0.26 0.05
175 INT186263 Binding of TNF and GORASP1 1 0.10 0.99 0.05
176 INT302141 CDKN1C Regulation of CDKN1B 1 0.09 0.26 0.05
177 INT186383 Binding of Nos2 and GORASP1 1 0.12 0.93 0.05
178 INT186377 Binding of Irf1 and GORASP1 1 0.12 0.87 0.05
179 INT327822 INCENP Regulation of Gene_expression of Lep 1 0.00 0.5 0.05
180 INT302163 IFI27 Regulation of CDKN1A 1 0.11 0.26 0.05
181 INT253023 Binding of PTTG1 and Myc 1 0.16 0.22 0.04
182 INT268676 Binding of HDAC1 and BCOR 1 0.01 1.31 0.04
183 INT207702 CCND1 Regulation of MSMB 1 0.22 0.69 0.04
184 INT231605 Binding of PSMD1 and SGCG 1 0.02 0.34 0.04
185 INT267685 Binding of CENPJ and ARID1B 1 0.09 0.58 0.04
186 INT250151 Binding of GSS and MCM3 1 0.01 1.38 0.04
187 INT252897 Binding of PTTG1IP and PTTG1 1 0.04 0.15 0.04
188 INT252892 PTTG1IP Regulation of PTTG1 1 0.05 0.49 0.04
189 INT213607 Binding of CSNK1D and CLOCK 1 0.27 0.65 0.04
190 INT350434 Negative_regulation of HSP90AA1 Positive_regulation of Gene_expression of ATF3 1 0.32 2.44 0.04
191 INT213392 Binding of SELPLG and XPO1 1 0.02 0.31 0.04
192 INT176224 Binding of CDKN1A and PCNA 4 0.08 2.52 0.03
193 INT302159 TSC1 Positive_regulation of Transcription of CDKN1A 1 0.00 0.28 0.03
194 INT234196 ERBB2 Positive_regulation of Negative_regulation of HSP90AA1 1 0.19 0.79 0.03
195 INT261728 PSMB6 Negative_regulation of Transcription of F2R 1 0.01 0.17 0.03
196 INT303091 Rorb Regulation of CDKN1A 1 0.00 0.52 0.03
197 INT173612 FGFR1 Positive_regulation of INCENP 1 0.00 0.28 0.03
198 INT173613 BMP2 Positive_regulation of INCENP 1 0.00 0.28 0.03
199 INT318191 INCENP Negative_regulation of Gene_expression of VEGFA 1 0.00 1.05 0.03
200 INT261731 PSMB6 Regulation of COL5A2 1 0.00 0.21 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69592 Positive_regulation of PSMD1 27 0.70 17.83 18.98
2 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42
3 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
4 INT151747 Positive_regulation of PSMD2 26 0.68 17.48 17.89
5 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31
6 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
7 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99
8 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61
9 INT174838 Localization of INCENP 80 0.64 19.05 12.89
10 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
11 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37
12 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47
13 INT182440 Gene_expression of CCNE2 39 0.53 22.07 7.44
14 INT173639 Positive_regulation of INCENP 40 0.14 20.97 6.7
15 INT8101 Binding of INCENP 42 0.31 16.2 6.68
16 INT185879 Gene_expression of CDC6 9 0.39 5.18 6.46
17 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93
18 INT333909 Positive_regulation of Gene_expression of HDAC1 1 0.44 14.15 5.9
19 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
20 INT141151 Regulation of PSMD1 16 0.40 8.19 5.86
21 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56
22 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38
23 INT151748 Positive_regulation of Positive_regulation of PSMD2 4 0.49 4.45 5.35
24 INT99549 Gene_expression of CDKN1B 30 0.75 17 5.15
25 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
26 INT174189 Gene_expression of E2F2 19 0.49 12.58 4.71
27 INT17110 Gene_expression of PSMD1 60 0.65 19.57 4.69
28 INT69591 Positive_regulation of Positive_regulation of PSMD1 2 0.50 3.06 3.99
29 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96
30 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57
31 INT167446 Regulation of CCNA2 2 0.39 2.01 3.49
32 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
33 INT69593 Negative_regulation of PSMD1 11 0.57 4.06 3.33
34 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28
35 INT75500 Negative_regulation of Gene_expression of CCND1 21 0.57 11.59 3.24
36 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21
37 INT172551 Negative_regulation of INCENP 38 0.07 20.83 3.14
38 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07
39 INT51993 Gene_expression of PSMA5 5 0.75 2.59 2.92
40 INT140547 Negative_regulation of PSMB10 3 0.02 2.33 2.92
41 INT172177 Protein_catabolism of INCENP 18 0.37 6.34 2.91
42 INT54749 Binding of BTRC 7 0.09 0.88 2.9
43 INT77339 Positive_regulation of RRM2 5 0.41 1.36 2.88
44 INT75499 Positive_regulation of Positive_regulation of CDKN1A 12 0.60 7.28 2.84
45 INT85078 Positive_regulation of PCNA 36 0.49 17.06 2.81
46 INT27260 Gene_expression of DYNLL1 8 0.75 7.72 2.78
47 INT24443 Gene_expression of PSMD2 20 0.54 7.29 2.77
48 INT22739 Positive_regulation of DYNLL1 5 0.67 1.69 2.67
49 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66
50 INT163359 Gene_expression of RFC1 9 0.65 3.34 2.64
51 INT306835 Regulation of E2F2 1 0.39 2.52 2.62
52 INT60440 Localization of PSMD1 10 0.74 3.94 2.57
53 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54
54 INT99548 Positive_regulation of Gene_expression of CDKN1B 12 0.67 6.79 2.5
55 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48
56 INT222400 Negative_regulation of Localization of INCENP 4 0.02 1.82 2.46
57 INT338170 Regulation of Regulation of CDKN2A 1 0.44 0.96 2.46
58 INT213681 Gene_expression of TYMS 9 0.33 8.96 2.45
59 INT175703 Negative_regulation of E2F2 6 0.38 3.47 2.44
60 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31
61 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3
62 INT106616 Gene_expression of PSMB9 35 0.72 28.4 2.29
63 INT61784 Positive_regulation of CENPJ 27 0.51 11.46 2.28
64 INT163283 Gene_expression of E2F1 21 0.71 3.77 2.26
65 INT101572 Negative_regulation of Gene_expression of PCNA 24 0.53 13.87 2.21
66 INT219458 Negative_regulation of CCNA2 9 0.38 1.23 2.21
67 INT86999 Regulation of DYNLL1 5 0.44 2.85 2.18
68 INT173090 Regulation of INCENP 24 0.09 9.45 2.16
69 INT306869 Gene_expression of E2F4 1 0.58 1.1 2.11
70 INT104402 Positive_regulation of CCND1 15 0.70 11.77 2.08
71 INT22738 Negative_regulation of DYNLL1 17 0.57 6.68 2.06
72 INT177841 Gene_expression of CCNA2 2 0.50 0.64 1.97
73 INT99547 Positive_regulation of CDKN1B 18 0.67 8.42 1.96
74 INT201458 Negative_regulation of Gene_expression of CCNE2 3 0.07 1.71 1.96
75 INT69027 Binding of PSMA5 4 0.47 1.08 1.93
76 INT306836 Negative_regulation of Gene_expression of CDC6 1 0.19 1.28 1.88
77 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87
78 INT213676 Negative_regulation of Gene_expression of TYMS 2 0.08 1.95 1.83
79 INT174240 Negative_regulation of TYMS 12 0.57 6.35 1.82
80 INT68952 Localization of PCNA 17 0.62 5.64 1.78
81 INT181280 Regulation of Gene_expression of INCENP 5 0.07 4 1.78
82 INT148721 Binding of PSMD1 13 0.31 4.78 1.76
83 INT257820 Positive_regulation of PAFAH1B1 1 0.68 11.09 1.69
84 INT88412 Positive_regulation of CDK2 17 0.57 8.49 1.66
85 INT104331 Negative_regulation of Gene_expression of CDKN1A 24 0.57 13.68 1.63
86 INT159185 Positive_regulation of Gene_expression of PSMD2 3 0.40 1.4 1.63
87 INT306853 Binding of E2F4 1 0.28 1.37 1.63
88 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57
89 INT241672 Positive_regulation of CCNA2 4 0.44 1.56 1.57
90 INT164152 Negative_regulation of PSMD2 9 0.37 3.41 1.56
91 INT116116 Phosphorylation of CDK4 3 0.56 2.18 1.56
92 INT54750 Gene_expression of BTRC 4 0.14 0.99 1.55
93 INT161574 Localization of CENPJ 7 0.73 6.11 1.54
94 INT306844 Localization of CCNE2 6 0.21 3.81 1.52
95 INT306875 Localization of CDC6 1 0.34 1.51 1.52
96 INT241668 Negative_regulation of Transcription of CCNA2 1 0.27 0.44 1.5
97 INT182427 Binding of E2F2 7 0.23 2.78 1.49
98 INT104694 Positive_regulation of Localization of TUBA4A 1 0.00 2.71 1.49
99 INT58581 Binding of RPA1 8 0.44 1.68 1.44
100 INT69513 Regulation of PSMA5 2 0.60 1.04 1.43
101 INT125320 Negative_regulation of HSP90AA1 20 0.45 23.93 1.42
102 INT108587 Negative_regulation of PSMA5 1 0.57 1.73 1.42
103 INT159186 Positive_regulation of Gene_expression of DYNLL1 1 0.49 1.25 1.4
104 INT78470 Negative_regulation of Gene_expression of CDKN2A 14 0.59 14.44 1.38
105 INT333914 Transcription of HDAC1 1 0.34 3.04 1.37
106 INT328202 Gene_expression of RBL1 1 0.13 1.84 1.37
107 INT201463 Negative_regulation of CCNE2 7 0.39 3.31 1.36
108 INT171975 Negative_regulation of Gene_expression of INCENP 8 0.05 5.24 1.35
109 INT6018 Positive_regulation of PSMB9 7 0.60 4.36 1.33
110 INT219492 Negative_regulation of CDC6 2 0.20 1.74 1.31
111 INT160009 Transcription of CDKN1B 2 0.67 1.43 1.29
112 INT173877 Positive_regulation of Gene_expression of INCENP 14 0.08 7.83 1.28
113 INT63905 Regulation of RB1 13 0.62 12.67 1.28
114 INT306868 Positive_regulation of Gene_expression of E2F1 6 0.46 1.01 1.28
115 INT79660 Phosphorylation of PSMC6 3 0.80 0.45 1.28
116 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26
117 INT201466 Positive_regulation of Gene_expression of CCNE2 13 0.20 8.62 1.26
118 INT306857 Binding of E2F3 1 0.21 1.22 1.24
119 INT217827 Gene_expression of E2F5 2 0.46 2.3 1.21
120 INT118368 Positive_regulation of E2F1 10 0.69 0.8 1.13
121 INT260285 Gene_expression of E2F3 6 0.54 2.51 1.13
122 INT133898 Binding of HSP90AA1 17 0.30 8.83 1.12
123 INT91872 Gene_expression of RPA1 9 0.77 5.28 1.12
124 INT260447 Binding of HDAC1 8 0.23 4.47 1.12
125 INT126993 Binding of E2F1 5 0.44 1.39 1.12
126 INT328203 Positive_regulation of RBL1 1 0.12 2.62 1.12
127 INT160008 Positive_regulation of Transcription of CDKN1B 1 0.49 0.98 1.1
128 INT199979 Gene_expression of ITGB3BP 1 0.11 2.83 1.08
129 INT281849 Binding of RRM2 5 0.17 0.43 1.07
130 INT238440 Negative_regulation of Binding of E2F2 3 0.27 1.09 1.07
131 INT238433 Negative_regulation of Gene_expression of E2F2 2 0.27 1.01 1.07
132 INT67638 Positive_regulation of PSMA5 1 0.21 1.15 1.05
133 INT147602 Negative_regulation of CDK4 8 0.35 4.6 1.04
134 INT160012 Regulation of Gene_expression of CDKN1B 2 0.44 1.17 1.04
135 INT333907 Positive_regulation of HDAC1 4 0.32 3.07 1.03
136 INT106735 Phosphorylation of CDK2 11 0.79 4.03 1.02
137 INT47977 Localization of GORASP1 3 0.78 0.97 1.01
138 INT13882 Binding of PSMB9 3 0.15 2.84 1
139 INT257824 Localization of PAFAH1B1 1 0.74 6.58 1
140 INT27813 Regulation of CENPJ 12 0.29 14.26 0.99
141 INT306847 Positive_regulation of Gene_expression of CDC6 1 0.23 0.16 0.99
142 INT75251 Negative_regulation of Positive_regulation of DYNLL1 1 0.41 0.18 0.99
143 INT104693 Negative_regulation of TUBA4A 1 0.00 1.78 0.98
144 INT104697 Positive_regulation of Negative_regulation of TUBA4A 1 0.00 1.8 0.98
145 INT241665 Transcription of CCNA2 1 0.44 0.38 0.98
146 INT250699 Binding of CDK6 3 0.33 2.54 0.97
147 INT184992 Positive_regulation of CDC6 2 0.28 0.7 0.96
148 INT78322 Positive_regulation of PSME1 2 0.44 1.8 0.95
149 INT174188 Positive_regulation of Gene_expression of RB1 9 0.45 6.22 0.94
150 INT306846 Negative_regulation of Binding of E2F3 1 0.24 0.65 0.94
151 INT306891 Negative_regulation of E2F3 1 0.25 0.65 0.94
152 INT338168 Positive_regulation of Binding of CDKN2A 1 0.49 0.52 0.94
153 INT201465 Positive_regulation of CCNE2 6 0.13 3.13 0.92
154 INT144289 Negative_regulation of Positive_regulation of PSMC6 1 0.41 0.56 0.92
155 INT306851 Transcription of CCNE2 1 0.06 0.57 0.92
156 INT306882 Transcription of CDC6 1 0.24 0.57 0.92
157 INT144287 Positive_regulation of PSMC6 1 0.49 0.56 0.92
158 INT163280 Negative_regulation of Phosphorylation of CCND1 6 0.19 3.92 0.87
159 INT306888 Positive_regulation of Binding of E2F4 1 0.37 0.58 0.87
160 INT113841 Gene_expression of CCNB1 11 0.75 3.46 0.86
161 INT306862 Regulation of Gene_expression of E2F2 1 0.17 0.19 0.85
162 INT252442 Binding of RFC1 3 0.05 0.3 0.84
163 INT73261 Negative_regulation of DYNC1I2 1 0.02 0.77 0.83
164 INT306834 Positive_regulation of Gene_expression of E2F3 2 0.29 1 0.82
165 INT306840 Positive_regulation of Gene_expression of E2F4 1 0.37 0.58 0.82
166 INT306867 Positive_regulation of Gene_expression of E2F2 1 0.31 0.59 0.82
167 INT163289 Phosphorylation of CCND1 7 0.36 4.81 0.81
168 INT182077 Positive_regulation of RFC1 3 0.07 1.65 0.81
169 INT95190 Gene_expression of NDEL1 1 0.29 0 0.81
170 INT306889 Positive_regulation of Gene_expression of E2F5 1 0.30 0.58 0.81
171 INT146521 Negative_regulation of Positive_regulation of CDKN1A 6 0.42 3.29 0.79
172 INT126990 Positive_regulation of Binding of E2F1 4 0.58 0 0.79
173 INT78323 Negative_regulation of PSME1 1 0.37 0.5 0.78
174 INT180752 Gene_expression of PAFAH1B1 3 0.66 9.89 0.75
175 INT108590 Negative_regulation of Negative_regulation of PSMA5 1 0.57 0.92 0.75
176 INT252975 Positive_regulation of Gene_expression of PTTG1 36 0.28 31.96 0.74
177 INT258791 Positive_regulation of CDK1 14 0.45 5.73 0.74
178 INT284955 Localization of HDAC1 2 0.47 1.71 0.74
179 INT104695 Localization of TUBA4A 1 0.00 1.36 0.74
180 INT251735 Binding of FEN1 1 0.17 1.13 0.74
181 INT40476 Negative_regulation of RFC1 5 0.18 2.85 0.72
182 INT306883 Negative_regulation of Phosphorylation of CDK4 1 0.17 1.06 0.71
183 INT257817 Regulation of PAFAH1B1 1 0.60 4.93 0.7
184 INT62273 Gene_expression of CDK1 19 0.75 8.43 0.68
185 INT105330 Gene_expression of CDK2 31 0.63 13.7 0.67
186 INT108586 Positive_regulation of Negative_regulation of PSMA5 1 0.49 0.82 0.67
187 INT181282 Transcription of INCENP 10 0.11 1.21 0.66
188 INT70537 Localization of DYNC1I2 2 0.23 0.21 0.66
189 INT353152 Localization of PRKACA 1 0.01 1.15 0.66
190 INT106608 Regulation of Gene_expression of SKP2 1 0.50 0.26 0.63
191 INT106603 Gene_expression of SKP2 5 0.63 6.99 0.62
192 INT251026 Negative_regulation of Phosphorylation of CDKN2A 5 0.42 5.02 0.62
193 INT306884 Negative_regulation of E2F4 1 0.44 0.61 0.62
194 INT35943 Positive_regulation of NDEL1 1 0.31 0 0.62
195 INT306839 Negative_regulation of Gene_expression of E2F1 2 0.39 0.24 0.61
196 INT113846 Negative_regulation of Positive_regulation of CDK2 1 0.48 0.39 0.6
197 INT147598 Negative_regulation of Positive_regulation of CDKN2A 3 0.41 1.47 0.59
198 INT93002 Binding of GORASP1 2 0.36 2.81 0.59
199 INT252443 Regulation of RFC1 1 0.03 0.35 0.59
200 INT128498 Regulation of CCND1 17 0.39 12.51 0.58
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