GO:0000287

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Name magnesium ion binding
Categary Function
Go Slim No
Go Link GO:0000287
Unique Molecular Interactions 678
Total Molecular Interactions 894
Total Single Events 7621
Pain Genes Associated 117

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for magnesium ion binding. They are ordered first by their pain relevance and then by number of times they were reported for magnesium ion binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22
2 INT44716 Binding of ABL2 and PDYN 2 0.40 0.66 4.77
3 INT259209 Binding of Glul and Flna 1 0.03 0 4.2
4 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
5 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
6 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
7 INT96465 Pnoc Positive_regulation of GEM 1 0.01 0.74 2.39
8 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
9 INT139768 Binding of TRPV1 and ICK 1 0.41 1.59 1.42
10 INT139767 ICK Regulation of TRPV1 1 0.30 1.59 1.42
11 INT128913 Binding of COMT and PENK 1 0.30 0.07 1.41
12 INT128914 COMT Regulation of OPRM1 1 0.39 0.07 1.39
13 INT63407 Binding of Oprl1 and Pck1 1 0.40 0 1.29
14 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27
15 INT87026 ZAK Positive_regulation of Gene_expression of IL12A 3 0.12 2.55 1.26
16 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
17 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18
18 INT261617 SNRNP70 Regulation of Comt 1 0.01 0.4 1.18
19 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18
20 INT197051 Binding of HLA-E and ATP8A1 1 0.00 6.52 1.14
21 INT117504 OPA1 Positive_regulation of CPP 1 0.09 1.09 1.13
22 INT62381 ADCY10 Positive_regulation of Localization of IGHG3 1 0.04 0.36 1.11
23 INT62380 ADCY10 Positive_regulation of IGHG3 1 0.03 0.36 1.11
24 INT341897 Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt 1 0.32 0.42 1.07
25 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04
26 INT33142 Pck1 Positive_regulation of Npr1 4 0.01 0.5 1.02
27 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
28 INT157142 OPA1 Positive_regulation of Gene_expression of Camk2a 1 0.02 0.3 1.02
29 INT102554 HGF Positive_regulation of Phosphorylation of RPS6KA1 1 0.21 0.93 0.94
30 INT265649 TBK1 Negative_regulation of COMT 1 0.01 0.61 0.94
31 INT165627 Binding of COMT and SLTM 1 0.09 0.86 0.88
32 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
33 INT31950 PIF1 Positive_regulation of Localization of Prl 1 0.06 0 0.87
34 INT202254 Binding of COMT and DRD2 1 0.41 0.23 0.86
35 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
36 INT80793 Prkcg Regulation of Pkm2 1 0.29 0.2 0.83
37 INT74383 Sst Positive_regulation of GEM 1 0.01 0.09 0.82
38 INT74382 Negative_regulation of Sst Positive_regulation of GEM 1 0.00 0.09 0.82
39 INT320120 MTX1 Positive_regulation of PTEN 1 0.04 0.09 0.82
40 INT74384 Regulation of Sst Positive_regulation of GEM 1 0.00 0.09 0.82
41 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
42 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78
43 INT107596 Binding of PPA1 and OPLL 1 0.00 1.13 0.77
44 INT180496 Binding of CTS and PDXK 1 0.04 0.69 0.77
45 INT49585 Binding of Glul and Selenbp2 1 0.20 0.19 0.76
46 INT125626 Binding of Calca and Atp8a2 1 0.00 0.4 0.76
47 INT31776 Positive_regulation of Gclc Positive_regulation of G6pd 1 0.29 0.19 0.75
48 INT111194 Binding of NEUROD1 and Pck1 1 0.39 0 0.75
49 INT266100 Binding of COMT and SH2B2 1 0.25 1.22 0.74
50 INT266108 Binding of COMT and HPS1 1 0.23 1.21 0.74
51 INT251729 Binding of FEN1 and EXOSC1 1 0.19 1.13 0.74
52 INT218933 Cyp3a23/3a1 Regulation of Alpi 1 0.00 1.07 0.73
53 INT287132 Binding of NT5E and Comt 1 0.03 0.11 0.73
54 INT73838 IGHD4-4 Positive_regulation of CDC42BPG 1 0.00 0 0.71
55 INT130356 Adcy10 Negative_regulation of Positive_regulation of Crp 1 0.13 0.23 0.71
56 INT105809 ATP8A2 Positive_regulation of P2RX2 1 0.13 0.11 0.7
57 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
58 INT31951 Negative_regulation of PIF1 Positive_regulation of Prl 1 0.07 0 0.68
59 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
60 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67
61 INT88194 ZAK Positive_regulation of Gene_expression of IL1B 1 0.07 0.94 0.66
62 INT130357 Adcy10 Regulation of Fgg 1 0.03 0.2 0.66
63 INT130354 Adcy10 Regulation of Serpine1 1 0.17 0.2 0.66
64 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 2 0.03 0.24 0.65
65 INT50634 Ddc Regulation of Gene_expression of Glul 1 0.02 0 0.65
66 INT281078 Prkacb Positive_regulation of Gene_expression of Adcy1 1 0.03 0 0.63
67 INT281090 Prkacb Positive_regulation of Mapk1 1 0.06 0 0.62
68 INT9163 Tnf Regulation of Gene_expression of Glul 1 0.12 1.99 0.62
69 INT281091 Prkacb Positive_regulation of Mdk 1 0.02 0 0.62
70 INT321300 Ins1 Negative_regulation of Pck1 1 0.09 0.52 0.59
71 INT346412 Binding of Tesc and Sv2a 1 0.02 0.6 0.59
72 INT87024 Positive_regulation of ZAK Positive_regulation of Localization of IFNG 2 0.05 0.81 0.58
73 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
74 INT120870 Binding of Wnk1 and Sptlc1 1 0.14 1.24 0.56
75 INT116369 Binding of Calca and Atp8a2 1 0.02 0.38 0.56
76 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56
77 INT84861 Rps6ka3 Positive_regulation of Transcription of APRT 1 0.28 0.19 0.55
78 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53
79 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
80 INT292075 FSCN1 Positive_regulation of Gene_expression of Csnk1a1 1 0.03 0.57 0.52
81 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
82 INT167455 Binding of MSD and Comt 1 0.15 0.28 0.5
83 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49
84 INT153658 PRKCA Negative_regulation of GEM 1 0.01 0.22 0.46
85 INT79624 CDC42BPG Positive_regulation of Binding of CRYGS 1 0.02 0.25 0.46
86 INT117890 Positive_regulation of Gfap Regulation of Glul 1 0.51 0.36 0.46
87 INT218932 Cyp3a23/3a1 Regulation of Gene_expression of Alpi 1 0.00 0.53 0.46
88 INT31952 Localization of PIF1 Regulation of Localization of Prl 1 0.04 0 0.46
89 INT117887 Glul Regulation of Arc 1 0.02 0.37 0.46
90 INT177782 PDCD2 Positive_regulation of MTHFD2 1 0.06 0.76 0.46
91 INT117889 Gfap Regulation of Glul 1 0.30 0.36 0.46
92 INT31953 PIF1 Regulation of Localization of Prl 1 0.06 0 0.46
93 INT177787 BUB1B Positive_regulation of MTHFD2 1 0.15 0.76 0.46
94 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
95 INT346416 Binding of Tesc and Svs1 1 0.00 0.07 0.42
96 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
97 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
98 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
99 INT17308 Ifng Positive_regulation of Atp8a1 1 0.64 0.45 0.41
100 INT339493 Binding of Irak1 and Irak3 1 0.02 0.17 0.41
101 INT172094 Binding of Atp9a and Il27ra 1 0.01 0.98 0.4
102 INT66660 Pck1 Positive_regulation of Localization of Ptprg 1 0.07 0 0.4
103 INT172095 Binding of Atp9a and Trav6-3 1 0.03 0.98 0.39
104 INT321292 Fig4 Negative_regulation of Pck1 1 0.10 0.33 0.39
105 INT263433 Abl1 Regulation of Abl1 1 0.04 0.28 0.38
106 INT58969 TNF Regulation of Regulation of RPS6KA6 1 0.35 0.34 0.38
107 INT58967 TNF Regulation of RPS6KA6 1 0.18 0.33 0.38
108 INT148465 Positive_regulation of Ccl4 Positive_regulation of Gclc 1 0.32 0.06 0.38
109 INT311616 Binding of MET and Comt 1 0.01 0.2 0.37
110 INT148467 Ccl4 Positive_regulation of Gclc 1 0.32 0.05 0.37
111 INT263380 Binding of Src and Abl1 1 0.21 0 0.37
112 INT25763 Crh Positive_regulation of Prkacb 1 0.56 0.07 0.37
113 INT88192 IFNG Regulation of Gene_expression of ZAK 1 0.01 0.75 0.36
114 INT308889 Binding of Idh1 and Adp 1 0.02 0 0.36
115 INT87023 ZAK Positive_regulation of Gene_expression of IL36RN 1 0.03 0.62 0.36
116 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
117 INT308890 Binding of Idh1 and P2ry13 1 0.06 0 0.35
118 INT263383 Abl1 Regulation of Trib3 1 0.01 0.28 0.35
119 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35
120 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
121 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35
122 INT266402 Binding of S100P and Ager 1 0.00 2.25 0.35
123 INT21286 Binding of Oprd1 and Pck1 1 0.08 0 0.34
124 INT134080 OPA1 Negative_regulation of Phosphorylation of Gnb2l1 1 0.03 0.22 0.34
125 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
126 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
127 INT28006 NPC1 Negative_regulation of Positive_regulation of Rps6ka1 1 0.01 0.37 0.33
128 INT135891 S1pr1 Regulation of Prps1 1 0.01 0.15 0.33
129 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
130 INT34449 Binding of Ca2 and Pck1 1 0.17 0.18 0.33
131 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33
132 INT155058 Stat3 Negative_regulation of Akp3 1 0.01 3.7 0.33
133 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33
134 INT151132 Negative_regulation of Map2k7 Negative_regulation of Gene_expression of Litaf 1 0.01 0.29 0.32
135 INT28005 NPC1 Negative_regulation of Rps6ka1 1 0.01 0.45 0.32
136 INT255933 Tauph Positive_regulation of Rps6ka5 1 0.00 0.1 0.32
137 INT284689 Binding of Tspo and Map3k12 1 0.00 0.59 0.32
138 INT255945 MAPK14 Positive_regulation of Rps6ka5 1 0.06 0.1 0.32
139 INT161435 OPA1 Positive_regulation of Gene_expression of Tnc 1 0.02 0.21 0.32
140 INT291240 Map3k8 Positive_regulation of Positive_regulation of Mapk1 1 0.16 0.72 0.32
141 INT291241 Map3k8 Positive_regulation of Gene_expression of Mapk1 1 0.17 0.72 0.32
142 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31
143 INT178910 Ins1 Negative_regulation of Gene_expression of Pck1 1 0.04 0.34 0.31
144 INT286702 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of Rps6ka5 1 0.37 0.18 0.29
145 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29
146 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29
147 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29
148 INT286705 Positive_regulation of Mapk1 Positive_regulation of Phosphorylation of Rps6ka5 1 0.37 0.18 0.29
149 INT286706 Mapk1 Positive_regulation of Phosphorylation of Rps6ka5 1 0.37 0.18 0.29
150 INT109098 Binding of ABL2 and PON1 1 0.36 1.32 0.28
151 INT229332 BAS Negative_regulation of Pck1 1 0.01 0.2 0.28
152 INT286701 Rps6ka5 Positive_regulation of Phosphorylation of Creb1 1 0.20 0.18 0.28
153 INT286707 Mapk1 Positive_regulation of Positive_regulation of Rps6ka5 1 0.37 0.18 0.28
154 INT156640 ATF4 Regulation of Gene_expression of S100P 1 0.44 0.88 0.28
155 INT291257 Map3k8 Regulation of Positive_regulation of MAPK1 1 0.09 1 0.28
156 INT218931 Cyp3a23/3a1 Regulation of Gene_expression of Akp3 1 0.00 0.55 0.27
157 INT47012 Regulation of Pck1 Positive_regulation of Npr1 1 0.01 0 0.26
158 INT305854 Polk Regulation of Gene_expression of Atp11c 1 0.05 0.73 0.26
159 INT205701 P2rx7 Positive_regulation of Il1 1 0.04 0.8 0.25
160 INT158621 Binding of SIGMAR1 and Sphk1 1 0.01 0 0.25
161 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24
162 INT287131 Negative_regulation of Binding of NT5E and Comt 1 0.03 0.06 0.23
163 INT292554 MAP3K5 Positive_regulation of MAPK8 1 0.08 0 0.23
164 INT292561 MAP3K5 Positive_regulation of Positive_regulation of RAC1 1 0.03 0 0.23
165 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
166 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
167 INT144800 Binding of TRPV1 and ATP8A2 1 0.22 0.14 0.23
168 INT167561 TRAP Positive_regulation of ATP8A2 1 0.17 0.56 0.23
169 INT346409 Negative_regulation of Binding of mn and Tesc 1 0.00 0.29 0.22
170 INT346408 Binding of mn and Tesc 1 0.00 0.29 0.22
171 INT187486 Binding of Prkag1 and Stk11 1 0.01 0.95 0.22
172 INT107219 Binding of P2rx7 and Atp5o 1 0.03 0.07 0.21
173 INT266103 Binding of COMT and SNRNP70 1 0.04 0.78 0.21
174 INT88191 Binding of NCOR2 and ZAK 1 0.00 0.17 0.21
175 INT216946 P2rx7 Regulation of Il10 1 0.28 0.17 0.21
176 INT182606 Binding of MSH2 and MSH3 1 0.12 1.4 0.21
177 INT107223 APEH Negative_regulation of P2rx7 1 0.00 0.13 0.21
178 INT202252 COMT Regulation of DRD2 1 0.31 0 0.21
179 INT274578 Binding of ABL1 and PSTPIP1 1 0.07 1.55 0.21
180 INT58968 TNF Positive_regulation of Gene_expression of RPS6KA6 1 0.36 0.2 0.21
181 INT317394 Binding of Stk11 and Amp1 1 0.04 0.89 0.21
182 INT302712 Binding of Hprt and Hrh1 1 0.25 1.07 0.2
183 INT203848 Binding of Pten and Lna1 1 0.06 0.4 0.2
184 INT112205 Pck1 Regulation of Rab38 1 0.00 0 0.2
185 INT25089 Glul Positive_regulation of Npr1 1 0.00 0 0.2
186 INT21576 NT5C3 Negative_regulation of Gene_expression of TIMP1 1 0.03 0.25 0.2
187 INT195423 COMT Negative_regulation of GBE1 1 0.00 0.22 0.19
188 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19
189 INT281477 Binding of Pten and Th 1 0.28 0.4 0.19
190 INT205710 CAMP Positive_regulation of P2rx7 1 0.02 0.47 0.19
191 INT21578 NT5C3 Regulation of Gene_expression of IL4I1 1 0.01 0.24 0.19
192 INT101812 Binding of KEAP1 and Positive_regulation of Gene_expression of GCLC 1 0.54 0.1 0.19
193 INT101808 Binding of NFE2L2 and Positive_regulation of Gene_expression of GCLC 1 0.54 0.1 0.19
194 INT65744 Map3k7 Negative_regulation of Gene_expression of Il2 1 0.10 0.74 0.18
195 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
196 INT332741 BPIFA1 Negative_regulation of ENO1 1 0.32 0.99 0.17
197 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17
198 INT155059 Csf2 Negative_regulation of Akp3 1 0.00 1.88 0.17
199 INT284558 Tlr4 Positive_regulation of Mat1a 1 0.14 0.24 0.17
200 INT156195 Binding of GEM and Kir3dl1 1 0.01 0.17 0.17

Single Events

The table below shows the top 100 pain related interactions that have been reported for magnesium ion binding. They are ordered first by their pain relevance and then by number of times they were reported in magnesium ion binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT12717 Binding of Pck1 85 0.47 12.49 54.81
2 INT122953 Gene_expression of COMT 65 0.77 25.84 40.49
3 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
4 INT9155 Gene_expression of Glul 60 0.77 17.97 23.95
5 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
6 INT2911 Positive_regulation of Glul 36 0.70 11.09 22.07
7 INT110638 Negative_regulation of COMT 43 0.59 21.03 21.05
8 INT519 Negative_regulation of Comt 52 0.59 17.65 20.39
9 INT292049 Gene_expression of Csnk1a1 1 0.59 28.22 19.53
10 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
11 INT135629 Binding of COMT 33 0.48 16.68 19.37
12 INT12922 Gene_expression of Atp9a 115 0.75 50.95 17.01
13 INT24798 Negative_regulation of Glul 52 0.55 27.25 15.17
14 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
15 INT116367 Binding of Atp8a2 33 0.28 6.42 13.3
16 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
17 INT17619 Regulation of COMT 12 0.45 8.46 12.22
18 INT520 Binding of Comt 24 0.48 8.98 12.21
19 INT204112 Gene_expression of GEM 43 0.75 38.74 11.23
20 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
21 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
22 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
23 INT144736 Negative_regulation of Gene_expression of COMT 13 0.58 6.47 9.28
24 INT122952 Positive_regulation of COMT 13 0.50 8.1 8.89
25 INT7663 Positive_regulation of Pck1 15 0.67 3.05 8.63
26 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
27 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
28 INT6810 Gene_expression of ENO2 70 0.78 54.8 8.35
29 INT6557 Gene_expression of Eno2 65 0.77 54.42 8.17
30 INT24799 Regulation of Glul 22 0.45 8.3 8
31 INT29142 Positive_regulation of Binding of Pck1 10 0.67 1.48 7.6
32 INT159946 Gene_expression of Mat1a 23 0.77 15.33 7.49
33 INT144739 Regulation of Gene_expression of COMT 11 0.61 3.07 7.08
34 INT50633 Regulation of Gene_expression of Glul 12 0.60 1.64 6.59
35 INT292062 Negative_regulation of Csnk1a1 1 0.44 7.57 6.52
36 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
37 INT50712 Gene_expression of Comt 13 0.68 6.33 6.23
38 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
39 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
40 INT161352 Gene_expression of Map3k12 3 0.24 0.59 6.16
41 INT25193 Negative_regulation of Pck1 20 0.57 5.66 6.05
42 INT1493 Positive_regulation of Prkacb 8 0.59 2.75 5.99
43 INT169697 Negative_regulation of Ephx2 35 0.59 38.21 5.92
44 INT86799 Gene_expression of Pck1 20 0.65 6.22 5.8
45 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45
46 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
47 INT292072 Positive_regulation of Gene_expression of Csnk1a1 1 0.53 9.76 5.39
48 INT2162 Regulation of Comt 13 0.60 2.9 5.18
49 INT22707 Positive_regulation of Eno2 36 0.69 27.31 5.07
50 INT38251 Negative_regulation of Gclc 7 0.57 1.37 5.06
51 INT33854 Localization of OPA1 19 0.65 10.55 5.04
52 INT29893 Negative_regulation of Prkacb 4 0.37 1.14 5.04
53 INT15652 Positive_regulation of ENO2 37 0.68 33.39 5.02
54 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5
55 INT162365 Gene_expression of Map3k8 33 0.58 22.75 4.95
56 INT125624 Gene_expression of Atp8a2 12 0.15 3.91 4.85
57 INT131176 Gene_expression of Srr 8 0.64 3.29 4.81
58 INT2871 Positive_regulation of Comt 9 0.50 2.8 4.78
59 INT204971 Gene_expression of Pink1 42 0.77 23.95 4.75
60 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
61 INT292060 Positive_regulation of Csnk1a1 1 0.53 6.03 4.57
62 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
63 INT25146 Negative_regulation of Positive_regulation of Glul 5 0.43 0.91 4.53
64 INT1490 Regulation of Prkacb 7 0.21 0.5 4.52
65 INT26229 Positive_regulation of ATP8A2 6 0.67 2.1 4.48
66 INT4683 Negative_regulation of PDXK 17 0.55 12.81 4.39
67 INT50631 Positive_regulation of Gene_expression of Glul 9 0.43 3 4.37
68 INT96464 Positive_regulation of GEM 7 0.45 5.48 4.37
69 INT292057 Regulation of Csnk1a1 1 0.34 3.52 4.33
70 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
71 INT50646 Transcription of Glul 12 0.38 3.59 4.07
72 INT170455 Gene_expression of Atp8a1 66 0.75 24.63 3.94
73 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
74 INT131178 Positive_regulation of Srr 4 0.56 4.78 3.91
75 INT34441 Negative_regulation of Binding of Pck1 6 0.42 0.76 3.8
76 INT162366 Positive_regulation of Map3k8 24 0.50 15.69 3.71
77 INT54116 Negative_regulation of Eno2 6 0.41 2.78 3.71
78 INT10744 Positive_regulation of PIF1 11 0.66 3.95 3.69
79 INT328127 Gene_expression of Atp10a 1 0.75 6.42 3.67
80 INT161105 Gene_expression of Ephx2 20 0.78 17.84 3.58
81 INT65072 Gene_expression of TKT 16 0.65 17.58 3.55
82 INT151171 Positive_regulation of Pten 20 0.55 13.3 3.54
83 INT88197 Binding of ZAK 9 0.46 6.23 3.54
84 INT50648 Negative_regulation of Gene_expression of Glul 9 0.58 2.7 3.53
85 INT12923 Negative_regulation of Atp9a 17 0.35 7.87 3.52
86 INT66570 Localization of Glul 4 0.78 0.37 3.45
87 INT24883 Regulation of OPA1 14 0.45 9.73 3.44
88 INT23467 Gene_expression of S100P 13 0.78 8.01 3.44
89 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
90 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36
91 INT102741 Gene_expression of Atp9b 20 0.75 8.01 3.34
92 INT162368 Negative_regulation of Map3k8 17 0.42 7.96 3.34
93 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
94 INT134413 Gene_expression of HPGDS 20 0.77 8.93 3.28
95 INT133086 Positive_regulation of Phosphorylation of Map2k7 1 0.05 4.34 3.27
96 INT81280 Binding of Atp9a 20 0.47 11.14 3.24
97 INT12843 Regulation of Pck1 13 0.60 3.46 3.18
98 INT292056 Localization of Csnk1a1 1 0.57 3.99 3.17
99 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
100 INT64748 Regulation of Binding of Pck1 4 0.44 0.45 3.15
101 INT346398 Binding of Tesc 1 0.02 1.88 3.14
102 INT192676 Binding of PTEN 14 0.46 10.58 3.06
103 INT123595 Regulation of Snca 7 0.62 4.3 3.06
104 INT133082 Phosphorylation of Map2k7 5 0.15 4.27 3.05
105 INT5913 Binding of OPA1 12 0.41 9.33 2.92
106 INT11920 Regulation of ENO2 18 0.55 11.51 2.89
107 INT102565 Positive_regulation of Phosphorylation of RPS6KA1 1 0.25 2.77 2.85
108 INT3605 Negative_regulation of OPA1 14 0.38 10.88 2.84
109 INT4313 Localization of PIF1 8 0.39 0.38 2.83
110 INT108433 Negative_regulation of Mat1a 16 0.57 14.15 2.82
111 INT91647 Gene_expression of PDXK 2 0.49 7.71 2.82
112 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8
113 INT54331 Positive_regulation of Glul 8 0.67 3.55 2.74
114 INT194289 Transcription of COMT 3 0.72 3.56 2.72
115 INT221097 Negative_regulation of Atp8a1 15 0.57 10.52 2.65
116 INT202257 Localization of COMT 7 0.75 2.13 2.65
117 INT138437 Gene_expression of Sphk1 23 0.65 10.01 2.61
118 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
119 INT204116 Regulation of Gene_expression of GEM 8 0.29 8.66 2.6
120 INT128983 Protein_catabolism of Comt 5 0.87 0.22 2.6
121 INT204110 Positive_regulation of Gene_expression of GEM 11 0.67 8.85 2.57
122 INT162682 Phosphorylation of Atp9a 1 0.80 0 2.57
123 INT287307 Binding of ENO1 9 0.48 11.24 2.51
124 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5
125 INT292070 Binding of Csnk1a1 1 0.28 3.18 2.5
126 INT130633 Negative_regulation of Gene_expression of Pck1 6 0.37 3.19 2.48
127 INT265662 Negative_regulation of Binding of COMT 4 0.37 1.29 2.42
128 INT24129 Positive_regulation of ZAK 13 0.70 2.29 2.39
129 INT153108 Transcription of Srr 4 0.57 1.41 2.38
130 INT27114 Gene_expression of Atp11c 20 0.42 22.22 2.37
131 INT86797 Regulation of Gene_expression of Pck1 6 0.44 1.12 2.36
132 INT44544 Gene_expression of ENOPH1 18 0.76 10.28 2.35
133 INT167858 Regulation of Gene_expression of Mat1a 3 0.61 2.97 2.33
134 INT128926 Gene_expression of Map2k7 5 0.23 3.01 2.31
135 INT100886 Gene_expression of GCLC 16 0.76 5.63 2.29
136 INT85284 Negative_regulation of ENO2 8 0.58 7.86 2.28
137 INT95621 Gene_expression of Gck 6 0.64 1.06 2.26
138 INT12112 Regulation of ICK 5 0.14 0.76 2.26
139 INT17617 Gene_expression of ABL2 8 0.75 2.73 2.25
140 INT76160 Phosphorylation of Prkacb 4 0.09 0.19 2.24
141 INT131177 Regulation of Gene_expression of Srr 3 0.51 0.4 2.22
142 INT129871 Positive_regulation of Gene_expression of Gck 1 0.28 0.15 2.19
143 INT179885 Regulation of PTEN 8 0.26 11.88 2.18
144 INT19804 Negative_regulation of Hprt 18 0.59 20.6 2.17
145 INT136962 Protein_catabolism of COMT 4 0.89 1.12 2.14
146 INT145196 Gene_expression of Irak3 5 0.23 4.23 2.13
147 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
148 INT145195 Positive_regulation of Irak3 4 0.15 3.65 2.12
149 INT224615 Negative_regulation of Gene_expression of Pten 7 0.59 2.99 2.09
150 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
151 INT56817 Regulation of Eno2 16 0.61 10.64 1.99
152 INT100897 Positive_regulation of Gene_expression of GCLC 9 0.68 1.84 1.99
153 INT101432 Positive_regulation of Gene_expression of Atp9a 13 0.10 7.86 1.95
154 INT51000 Positive_regulation of Atp9a 12 0.49 5.63 1.93
155 INT3496 Negative_regulation of HPRT1 7 0.58 25.05 1.92
156 INT85359 Negative_regulation of Map3k12 6 0.51 0.07 1.89
157 INT80221 Regulation of Eno2 4 0.35 4.64 1.89
158 INT127125 Localization of Snca 6 0.81 8.24 1.88
159 INT167853 Positive_regulation of Gene_expression of Mat1a 5 0.35 3.8 1.88
160 INT49584 Negative_regulation of Glul 3 0.52 1.16 1.88
161 INT138439 Positive_regulation of Gene_expression of Sphk1 14 0.48 5.93 1.86
162 INT154816 Negative_regulation of Sphk1 19 0.41 11.38 1.84
163 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
164 INT44723 Positive_regulation of ABL2 7 0.49 2.23 1.82
165 INT447 Localization of Comt 4 0.75 0.76 1.8
166 INT133084 Positive_regulation of Gene_expression of Map2k7 3 0.17 2.56 1.8
167 INT48596 Positive_regulation of NT5C3 3 0.45 0.53 1.79
168 INT259220 Binding of Glul 3 0.36 0.61 1.78
169 INT168068 Positive_regulation of Mat1a 3 0.46 8.82 1.77
170 INT178389 Positive_regulation of Eno2 3 0.06 1.01 1.76
171 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74
172 INT226868 Transcription of Map3k8 2 0.52 17.13 1.73
173 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7
174 INT56201 Negative_regulation of Negative_regulation of Glul 2 0.31 0.97 1.69
175 INT281639 Binding of Map3k12 2 0.02 3.05 1.68
176 INT41395 Positive_regulation of Gclc 9 0.61 1.34 1.66
177 INT116368 Localization of Atp8a2 4 0.07 1.43 1.66
178 INT50645 Positive_regulation of Positive_regulation of Glul 2 0.21 0.42 1.66
179 INT263398 Positive_regulation of Abl1 1 0.60 1.44 1.66
180 INT131179 Positive_regulation of Gene_expression of Srr 4 0.57 0.87 1.63
181 INT292052 Regulation of Gene_expression of Csnk1a1 1 0.47 2.5 1.62
182 INT107992 Gene_expression of MSH2 39 0.78 37.09 1.6
183 INT88726 Gene_expression of HPRT1 36 0.78 10.12 1.58
184 INT161371 Gene_expression of Glul 7 0.61 2.44 1.58
185 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
186 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
187 INT101431 Negative_regulation of Gene_expression of Atp9a 12 0.06 4.64 1.57
188 INT265659 Positive_regulation of Negative_regulation of COMT 1 0.43 0.78 1.57
189 INT82866 Localization of Atp9a 13 0.78 6.95 1.56
190 INT88195 Gene_expression of ZAK 15 0.74 4.79 1.55
191 INT203508 Gene_expression of Eno2 12 0.65 4.98 1.55
192 INT151169 Positive_regulation of Gene_expression of Pten 15 0.45 12.88 1.53
193 INT291207 Positive_regulation of Transcription of Map3k8 1 0.50 11.36 1.53
194 INT287309 Positive_regulation of ENO1 5 0.59 5.67 1.52
195 INT14048 Negative_regulation of TKT 13 0.34 5.05 1.51
196 INT24414 Negative_regulation of ATP8A2 5 0.43 1.63 1.46
197 INT28003 Positive_regulation of Rps6ka1 4 0.16 2.25 1.46
198 INT159947 Negative_regulation of Gene_expression of Mat1a 2 0.42 4.01 1.46
199 INT228249 Binding of Pten 7 0.48 3.26 1.45
200 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
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