GO:0000288

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Name nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Categary Process
Go Slim No
Go Link GO:0000288
Unique Molecular Interactions 54
Total Molecular Interactions 64
Total Single Events 469
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. They are ordered first by their pain relevance and then by number of times they were reported for nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182159 Binding of HGF and DCPS 1 0.01 2.5 1.17
2 INT315185 Binding of CNOT1 and Tg(CAG-EGFP)D4Nagy 1 0.04 0.16 0.74
3 INT251729 Binding of FEN1 and EXOSC1 1 0.19 1.13 0.74
4 INT102599 Binding of EXOSC3 and TPPP3 3 0.39 2.61 0.48
5 INT182150 Binding of APC and DCPS 1 0.02 1.14 0.48
6 INT149652 Zfp36 Regulation of Nos2 1 0.09 0.42 0.47
7 INT182158 Binding of IL3RA and DCPS 1 0.06 0.77 0.39
8 INT329170 DCPS Positive_regulation of Gene_expression of IFN1@ 1 0.04 1.55 0.36
9 INT355982 Binding of HLA-DQA2 and DCPS 1 0.00 1.33 0.26
10 INT355983 CSF2 Regulation of Gene_expression of DCPS 1 0.02 0.84 0.25
11 INT355985 IDO1 Positive_regulation of Gene_expression of DCPS 1 0.02 1.21 0.23
12 INT337168 DCPS Negative_regulation of CD86 1 0.02 1.54 0.21
13 INT225649 IL4 Positive_regulation of Localization of DCPS 1 0.02 1.03 0.19
14 INT182152 DCPS Positive_regulation of IFNA1 1 0.02 0.45 0.18
15 INT182149 DCPS Positive_regulation of Binding of IFNA1 1 0.02 0.45 0.18
16 INT182155 DCPS Positive_regulation of Positive_regulation of ITGAX 1 0.04 0.46 0.18
17 INT97889 Binding of RQCD1 and NPS 1 0.13 1.69 0.17
18 INT341239 Binding of EIF4E and Eif4e 1 0.08 0.23 0.12
19 INT341238 Binding of EIF4E and Eif4g3 1 0.03 0.23 0.12
20 INT182154 Binding of HLA-DRA and DCPS 1 0.01 0.23 0.12
21 INT44591 PLAT Negative_regulation of CNOT4 1 0.10 0.33 0.1
22 INT111866 Binding of LNPEP and CNOT4 1 0.02 0 0.09
23 INT264188 DCPS Positive_regulation of Gene_expression of IL10 1 0.02 0.59 0.08
24 INT225650 DCPS Positive_regulation of PDHA1 1 0.00 0.41 0.07
25 INT203419 Binding of EIF4A1 and Gtf3a 1 0.00 0.5 0.07
26 INT84752 Binding of HRAS and DCPS 1 0.18 2.61 0.07
27 INT229601 Binding of DIS3 and RLS 1 0.14 2.19 0.06
28 INT265386 DCPS Positive_regulation of Localization of CXCL10 1 0.01 0.07 0.05
29 INT353667 Binding of CXCL10 and DCPS 1 0.00 0.34 0.04
30 INT353670 Binding of DCPS and SENP8 1 0.00 0.34 0.04
31 INT173199 CNOT4 Regulation of Regulation of Myc 1 0.01 0.66 0.03
32 INT260946 Zfp36 Negative_regulation of Binding of Elavl1 1 0.21 0.11 0.03
33 INT222259 EIF4E Regulation of Negative_regulation of NOD2 1 0.13 0.1 0
34 INT245701 CNOT1 Positive_regulation of H2-Q9 1 0.01 0.31 0
35 INT211779 Binding of EIF4G1 and NTSR1 1 0.02 0 0
36 INT341232 Binding of EIF4A2 and Eif4e 1 0.06 0 0
37 INT353660 Binding of ICAM3 and DCPS 1 0.01 1.43 0
38 INT341240 Binding of EIF4E and Eif4ebp1 1 0.04 0.5 0
39 INT351873 NR4A1 Positive_regulation of EXOSC1 1 0.04 0 0
40 INT307284 DCP2 Positive_regulation of HAL 1 0.00 0 0
41 INT269275 Binding of CNOT1 and Mecr 1 0.36 0.06 0
42 INT277811 Binding of CD28 and DCPS 1 0.04 0.05 0
43 INT217777 EIF4E Regulation of Gene_expression of MAP3K3 1 0.05 0.19 0
44 INT115239 Binding of Casp1 and EXOSC3 1 0.40 0.11 0
45 INT341234 Eif4g3 Positive_regulation of Binding of EIF4E 1 0.04 0 0
46 INT351874 Positive_regulation of NR4A1 Positive_regulation of EXOSC1 1 0.04 0 0
47 INT217790 EIF4E Regulation of Gene_expression of RASGRP1 1 0.01 0.19 0
48 INT293811 Negative_regulation of EIF4E Negative_regulation of Gene_expression of CCND3 1 0.02 0.32 0
49 INT341230 Eif4g3 Positive_regulation of EIF4E 1 0.04 0 0
50 INT229602 Binding of ETFA and DIS3 1 0.08 1.12 0
51 INT341233 Positive_regulation of Binding of EIF4E and Eif4ebp1 1 0.06 0.5 0
52 INT307286 Binding of PMP2 and DCP2 1 0.04 0 0
53 INT172981 PAN3 Negative_regulation of SMAD4 1 0.01 0.98 0
54 INT285641 Zfp36 Negative_regulation of Egr1 1 0.06 0.28 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. They are ordered first by their pain relevance and then by number of times they were reported in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT45142 Gene_expression of DCPS 109 0.56 84.71 16.87
2 INT159631 Positive_regulation of DCPS 60 0.27 43.23 10.3
3 INT159632 Localization of DCPS 24 0.21 18.24 6.8
4 INT154303 Negative_regulation of DCPS 27 0.36 33.83 5.45
5 INT143494 Binding of DCPS 24 0.29 24.41 3.67
6 INT167478 Positive_regulation of Gene_expression of DCPS 23 0.27 14.75 3.37
7 INT198568 Regulation of DCPS 17 0.34 16.26 1.86
8 INT219752 Localization of EXOSC1 4 0.78 6.92 1.19
9 INT27314 Negative_regulation of CNOT4 4 0.00 1.64 0.98
10 INT156641 Positive_regulation of CNOT4 4 0.07 3.19 0.9
11 INT182167 Transcription of DCPS 1 0.11 1.94 0.82
12 INT355989 Positive_regulation of Localization of DCPS 1 0.05 1.83 0.8
13 INT182182 Positive_regulation of Positive_regulation of DCPS 4 0.08 3.32 0.7
14 INT304293 Positive_regulation of Negative_regulation of DCPS 2 0.08 3.17 0.64
15 INT89100 Gene_expression of CNOT1 7 0.65 1.76 0.59
16 INT159634 Negative_regulation of Positive_regulation of DCPS 2 0.13 2.39 0.58
17 INT214855 Regulation of Positive_regulation of CNOT4 1 0.02 0.66 0.53
18 INT182178 Regulation of Gene_expression of DCPS 4 0.07 3.16 0.51
19 INT149643 Binding of Zfp36 2 0.29 0.45 0.49
20 INT304297 Negative_regulation of Negative_regulation of DCPS 4 0.08 4.43 0.47
21 INT254389 Negative_regulation of Gene_expression of DCPS 6 0.08 7.26 0.44
22 INT204827 Positive_regulation of Zfp36 1 0.26 0.33 0.43
23 INT156643 Positive_regulation of Positive_regulation of CNOT4 2 0.05 1.64 0.39
24 INT111872 Binding of CNOT4 4 0.02 1.11 0.37
25 INT41179 Negative_regulation of EXOSC3 1 0.42 0.08 0.35
26 INT159633 Negative_regulation of Localization of DCPS 1 0.13 0.1 0.34
27 INT156647 Transcription of CNOT4 1 0.07 0.79 0.32
28 INT156650 Positive_regulation of Transcription of CNOT4 1 0.05 0.79 0.32
29 INT118490 Regulation of CNOT4 2 0.02 1.18 0.27
30 INT44599 Gene_expression of CNOT4 4 0.40 3.09 0.25
31 INT211839 Binding of EIF4E 8 0.36 0.79 0.18
32 INT138681 Gene_expression of PAN3 2 0.05 1.77 0.18
33 INT327283 Negative_regulation of Zfp36 1 0.39 0.5 0.18
34 INT192952 Negative_regulation of DIS3 1 0.21 0.42 0.15
35 INT200005 Positive_regulation of Binding of DCPS 1 0.02 0.87 0.14
36 INT353246 Gene_expression of EIF4G1 1 0.06 1.23 0.14
37 INT118190 Positive_regulation of CNOT1 1 0.00 0 0.14
38 INT194022 Negative_regulation of RQCD1 4 0.33 3.18 0.13
39 INT237845 Localization of DCP2 2 0.43 1.16 0.13
40 INT194023 Gene_expression of RQCD1 3 0.52 3.99 0.12
41 INT337213 Regulation of Positive_regulation of DCPS 1 0.02 0.7 0.1
42 INT135274 Positive_regulation of RQCD1 2 0.36 1.24 0.08
43 INT260907 Phosphorylation of Zfp36 1 0.54 0.47 0.08
44 INT154717 Regulation of Binding of DCPS 1 0.35 1.76 0.08
45 INT318117 Positive_regulation of PAN3 1 0.01 0.94 0.07
46 INT44603 Negative_regulation of Gene_expression of CNOT4 1 0.30 0.24 0.06
47 INT260911 Regulation of Phosphorylation of Zfp36 1 0.30 0.23 0.04
48 INT181834 Localization of CNOT1 1 0.73 0.28 0.04
49 INT307299 Binding of DCP2 1 0.06 0 0.03
50 INT233105 Localization of CNOT4 1 0.11 0.71 0.03
51 INT227664 Phosphorylation of EIF4E 6 0.46 0.74 0
52 INT328777 Gene_expression of EXOSC1 3 0.09 0.56 0
53 INT217806 Gene_expression of EIF4E 2 0.27 0.68 0
54 INT293778 Positive_regulation of EIF4E 2 0.45 0.42 0
55 INT260926 Regulation of Zfp36 2 0.21 0.47 0
56 INT237848 Positive_regulation of Localization of DCP2 1 0.29 0.94 0
57 INT303322 Positive_regulation of Phosphorylation of EIF4A2 1 0.08 0.16 0
58 INT237844 Gene_expression of DCP2 1 0.39 1.1 0
59 INT245700 Protein_catabolism of CNOT1 1 0.86 0.31 0
60 INT211840 Protein_catabolism of EIF4G1 1 0.35 0.13 0
61 INT211836 Binding of EIF4G1 1 0.12 0.07 0
62 INT225658 Protein_catabolism of DCPS 1 0.08 0.24 0
63 INT229605 Binding of DIS3 1 0.11 1.88 0
64 INT354311 Positive_regulation of Binding of CNOT4 1 0.01 0.39 0
65 INT240418 Binding of EXOSC1 1 0.03 0.47 0
66 INT351889 Negative_regulation of Gene_expression of EXOSC1 1 0.06 0 0
67 INT293768 Regulation of Binding of EIF4E 1 0.18 0.13 0
68 INT173011 Localization of PAN3 1 0.01 0.91 0
69 INT227668 Positive_regulation of Phosphorylation of EIF4E 1 0.20 0.15 0
70 INT276879 Regulation of Phosphorylation of EIF4E 1 0.25 0.21 0
71 INT149645 Positive_regulation of Gene_expression of Zfp36 1 0.14 0 0
72 INT351888 Regulation of EXOSC1 1 0.04 0 0
73 INT219228 Negative_regulation of Gene_expression of CNOT1 1 0.41 0.43 0
74 INT237841 Positive_regulation of Gene_expression of DCP2 1 0.29 0.3 0
75 INT293780 Positive_regulation of Binding of EIF4E 1 0.20 0.13 0
76 INT303318 Phosphorylation of EIF4A2 1 0.11 0.16 0
77 INT341209 Binding of EIF4A2 1 0.06 0 0
78 INT307294 Negative_regulation of Binding of DCP2 1 0.05 0 0
79 INT341208 Negative_regulation of Binding of EIF4E 1 0.14 0 0
80 INT149639 Gene_expression of Zfp36 1 0.22 0 0
81 INT293775 Regulation of EIF4E 1 0.24 0.64 0
82 INT307298 Regulation of DCP2 1 0.05 0 0
83 INT293761 Negative_regulation of EIF4E 1 0.17 0.85 0
84 INT351112 Positive_regulation of Positive_regulation of EIF4E 1 0.45 0.22 0
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