GO:0000320

From wiki-pain
Jump to: navigation, search
Name re-entry into mitotic cell cycle
Categary Process
Go Slim No
Go Link GO:0000320
Unique Molecular Interactions 119
Total Molecular Interactions 145
Total Single Events 1712
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for re-entry into mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for re-entry into mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
2 INT112870 Aap Positive_regulation of Gene_expression of Ccnd1 1 0.24 0.34 0.63
3 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58
4 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
5 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
6 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38
7 INT152453 Gsk3b Regulation of Nfkb1 1 0.02 1.68 0.36
8 INT66369 Pomc Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
9 INT242162 Binding of Ccnd1 and Wnt2 1 0.10 0.23 0.34
10 INT321366 Gsk3b Regulation of Gene_expression of CYP8B1 1 0.01 0.21 0.33
11 INT342810 Binding of Adarb1 and Gsk3b 1 0.00 0.36 0.3
12 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28
13 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
14 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21
15 INT261401 Binding of Gsk3b and ADHD1 1 0.00 1.62 0.18
16 INT327310 Binding of Ccnd1 and Elavl1 1 0.04 0.38 0.16
17 INT327325 Binding of Hnrnpd and Ccnd1 1 0.03 0.38 0.16
18 INT201722 Myc Regulation of Gene_expression of Ccnd1 1 0.03 0.79 0.13
19 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
20 INT312893 Gsk3b Positive_regulation of Hdac6 1 0.07 0.65 0.13
21 INT263320 Gsk3b Regulation of Uts2r 1 0.02 0.68 0.13
22 INT263318 Akt1 Regulation of Gsk3b 1 0.02 0.75 0.13
23 INT196433 Cdk4 Negative_regulation of Ccnd1 1 0.10 1.17 0.13
24 INT354327 Gsk3b Positive_regulation of Gene_expression of Ide 1 0.17 0.33 0.13
25 INT184522 Positive_regulation of Ptger2 Regulation of Localization of Ccnd1 1 0.01 0.95 0.11
26 INT268634 Ptpn2 Positive_regulation of Positive_regulation of Gsk3b 1 0.02 1.08 0.11
27 INT184521 Ptger2 Regulation of Localization of Ccnd1 1 0.01 0.94 0.11
28 INT289768 Akt1 Regulation of Phosphorylation of Gsk3b 1 0.04 0.45 0.11
29 INT184520 Ptger2 Regulation of Ccnd1 1 0.00 0.94 0.11
30 INT268626 Mpz Positive_regulation of Positive_regulation of Gsk3b 1 0.29 1.08 0.11
31 INT32546 Gsk3b Negative_regulation of Localization of Gnrh1 1 0.05 0 0.1
32 INT32547 Gsk3b Negative_regulation of Localization of LH 1 0.04 0 0.1
33 INT220511 Cav1 Negative_regulation of Transcription of Ccnd1 1 0.03 0.83 0.09
34 INT185279 Binding of CCND1 and CDK4 4 0.13 2.05 0.08
35 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08
36 INT268627 Ptpn2 Positive_regulation of Gsk3b 1 0.02 1.7 0.08
37 INT268630 Mpz Positive_regulation of Regulation of Gsk3b 1 0.18 0.57 0.07
38 INT340567 Jun Positive_regulation of Gene_expression of Ccnd1 1 0.05 0.27 0.07
39 INT354328 Gsk3b Regulation of Gs 1 0.16 0.84 0.07
40 INT354329 Gsk3b Regulation of Gene_expression of Gs 1 0.16 0.84 0.07
41 INT215693 Trib3 Regulation of Gene_expression of Ccnd1 1 0.00 0.09 0.07
42 INT221235 Akt1 Negative_regulation of Gsk3b 1 0.06 0.14 0.06
43 INT193966 AKT1 Negative_regulation of Gsk3b 1 0.05 0.75 0.05
44 INT193969 AKT1 Negative_regulation of Phosphorylation of Gsk3b 1 0.05 0.75 0.05
45 INT181814 Gsk3b Regulation of Gata4 1 0.06 0.37 0.05
46 INT193964 Mapk1 Negative_regulation of Gsk3b 1 0.00 0.74 0.05
47 INT316485 Stat3 Positive_regulation of Transcription of Ccnd1 1 0.23 1.27 0.04
48 INT207702 CCND1 Regulation of MSMB 1 0.22 0.69 0.04
49 INT290810 Gsk3b Regulation of Arntl 1 0.15 0 0.04
50 INT303092 Gsk3b Positive_regulation of NEUROG2 1 0.01 0.16 0.03
51 INT290808 Gsk3b Positive_regulation of Arntl 1 0.25 0.17 0.03
52 INT234981 Binding of Dsg3 and Negative_regulation of Gsk3b 1 0.07 0.3 0.03
53 INT277745 Trib3 Regulation of Ccnd1 1 0.00 0.41 0.03
54 INT303083 Rorb Regulation of Gsk3b 1 0.00 0.52 0.03
55 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
56 INT268629 Mpz Regulation of Phosphorylation of Gsk3b 1 0.26 1.05 0.03
57 INT223067 IFI27 Negative_regulation of CCND1 1 0.05 0.65 0.03
58 INT303079 Gsk3b Positive_regulation of Cebpg 1 0.08 0.16 0.03
59 INT265906 IGF1 Regulation of Gsk3b 1 0.25 1.31 0.03
60 INT337811 Gene_expression of Gsk3b Positive_regulation of Phosphorylation of Akt1 1 0.37 0.37 0.03
61 INT223066 CDKN1A Negative_regulation of CCND1 1 0.04 0.66 0.03
62 INT272517 Binding of Ccnd1 and Celf1 3 0.08 0.07 0
63 INT144030 STAT3 Regulation of CCND1 2 0.09 1.05 0
64 INT201771 CDKN1A Positive_regulation of Localization of Ccnd1 1 0.04 0 0
65 INT290811 Binding of Mgst1 and Gsk3b 1 0.05 0 0
66 INT290807 Positive_regulation of Akt1 Positive_regulation of Phosphorylation of Gsk3b 1 0.14 0 0
67 INT219409 CCNF Regulation of E2F2 1 0.22 0.11 0
68 INT219405 CCNF Regulation of PCNA 1 0.20 0.11 0
69 INT268628 Mpz Positive_regulation of Phosphorylation of Gsk3b 1 0.25 0.43 0
70 INT272518 Positive_regulation of Binding of Ccnd1 and Celf1 1 0.01 0 0
71 INT268635 Mpz Positive_regulation of Gsk3b 1 0.17 0.43 0
72 INT269948 Sox17 Positive_regulation of Gene_expression of Ccnd1 1 0.61 0.19 0
73 INT269920 Positive_regulation of Binding of Ccnd1 and Qsox1 1 0.10 0 0
74 INT224291 Negative_regulation of ESR1 Positive_regulation of CCND1 1 0.16 0.07 0
75 INT250658 FOS Positive_regulation of CCND1 1 0.03 0.6 0
76 INT290809 Binding of Arntl and Gsk3b 1 0.20 0 0
77 INT145338 Binding of PYGO1 and Positive_regulation of Transcription of CCND1 1 0.07 0 0
78 INT269925 Binding of Ccnd1 and Qsox1 1 0.07 0 0
79 INT338197 CCND1 Negative_regulation of AR 1 0.24 0 0
80 INT269949 Sox17 Positive_regulation of Ccnd1 1 0.61 0.96 0
81 INT219410 CCNF Regulation of HNF4A 1 0.01 0.11 0
82 INT219411 CCNF Regulation of SKP2 1 0.22 0.11 0
83 INT302154 STAT3 Regulation of Transcription of CCND1 1 0.04 0.99 0
84 INT315486 Slfn1 Negative_regulation of Ccnd1 1 0.07 0.28 0
85 INT276303 Negative_regulation of AKT1 Negative_regulation of CCND1 1 0.01 0.58 0
86 INT235077 Akt1 Positive_regulation of Phosphorylation of Gsk3b 1 0.07 0.53 0
87 INT285878 Negative_regulation of Binding of CCND1 and CDK4 1 0.00 0.44 0
88 INT269945 Sox17 Positive_regulation of Localization of Ccnd1 1 0.39 0 0
89 INT186051 IFI27 Regulation of Gene_expression of CCND1 1 0.30 0.66 0
90 INT269922 Sox17 Regulation of Ccnd1 1 0.47 0 0
91 INT281610 Positive_regulation of Akt1 Positive_regulation of Gsk3b 1 0.02 0.12 0
92 INT230713 Binding of Prkcd and Gsk3b 1 0.34 0 0
93 INT201756 CDKN1B Positive_regulation of Localization of Ccnd1 1 0.04 0 0
94 INT269931 Binding of Ccnd1 and Sox17 1 0.33 0.19 0
95 INT229007 MIA3 Positive_regulation of Gene_expression of Ccnd1 1 0.01 0.55 0
96 INT268632 Mpz Regulation of Gsk3b 1 0.22 0 0
97 INT290806 Gene_expression of Akt1 Positive_regulation of Phosphorylation of Gsk3b 1 0.14 0 0
98 INT303004 Adm Positive_regulation of Gsk3b 1 0.04 0.97 0
99 INT263319 Binding of Gsk3b and Uts2r 1 0.01 0 0
100 INT224290 ESR1 Positive_regulation of CCND1 1 0.17 0.07 0
101 INT314684 Binding of CCND1 and ESR1 1 0.22 0.42 0
102 INT145334 Binding of BCL9 and Positive_regulation of Transcription of CCND1 1 0.41 0 0
103 INT287071 Tlr4 Positive_regulation of Ccnd1 1 0.02 0.12 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for re-entry into mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in re-entry into mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
2 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
3 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
4 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34
5 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93
6 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4
7 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75
8 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27
9 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21
10 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83
11 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65
12 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53
13 INT75500 Negative_regulation of Gene_expression of CCND1 21 0.57 11.59 3.24
14 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07
15 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66
16 INT93396 Positive_regulation of Gene_expression of Ccnd1 13 0.52 8.59 2.26
17 INT93398 Negative_regulation of Gene_expression of Ccnd1 5 0.44 2.61 2.12
18 INT104402 Positive_regulation of CCND1 15 0.70 11.77 2.08
19 INT204018 Localization of Gsk3b 27 0.71 13.67 1.87
20 INT112867 Positive_regulation of Gene_expression of Ccnd1 15 0.56 13.22 1.77
21 INT108327 Negative_regulation of Gene_expression of Ccnd1 18 0.38 14.36 1.31
22 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16
23 INT128987 Negative_regulation of Ccnd1 24 0.52 15.78 1.15
24 INT134036 Regulation of Gsk3b 4 0.60 1.42 1.15
25 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11
26 INT208536 Positive_regulation of Positive_regulation of Gsk3b 6 0.30 4.83 1.11
27 INT144427 Transcription of Ccnd1 10 0.41 7.89 1.07
28 INT116646 Regulation of Negative_regulation of Gsk3b 2 0.44 0.39 0.99
29 INT59198 Regulation of Ccnd1 11 0.47 6.54 0.9
30 INT261360 Binding of Gsk3b 5 0.36 2.85 0.9
31 INT163280 Negative_regulation of Phosphorylation of CCND1 6 0.19 3.92 0.87
32 INT109007 Positive_regulation of Ccnd1 23 0.53 9.5 0.86
33 INT167285 Positive_regulation of Phosphorylation of Gsk3b 17 0.50 5.92 0.82
34 INT156945 Positive_regulation of Negative_regulation of Gsk3b 6 0.38 4.58 0.82
35 INT163289 Phosphorylation of CCND1 7 0.36 4.81 0.81
36 INT66365 Positive_regulation of Gene_expression of Gsk3b 2 0.07 0.95 0.81
37 INT116644 Phosphorylation of Gsk3b 4 0.61 0.68 0.78
38 INT204002 Negative_regulation of Gene_expression of Gsk3b 15 0.55 8.57 0.77
39 INT242137 Negative_regulation of Positive_regulation of Gsk3b 7 0.39 2.99 0.67
40 INT144432 Positive_regulation of Transcription of Ccnd1 4 0.36 2.36 0.63
41 INT204006 Negative_regulation of Localization of Gsk3b 6 0.40 1.66 0.6
42 INT128498 Regulation of CCND1 17 0.39 12.51 0.58
43 INT230679 Positive_regulation of Binding of Gsk3b 3 0.42 1.42 0.58
44 INT146802 Positive_regulation of Ccnd1 4 0.38 1.37 0.53
45 INT208537 Regulation of Gene_expression of Gsk3b 4 0.36 2.15 0.52
46 INT75498 Positive_regulation of Gene_expression of CCND1 21 0.68 19.4 0.51
47 INT258835 Localization of Ccnd1 3 0.53 2.7 0.5
48 INT146522 Negative_regulation of Positive_regulation of CCND1 3 0.30 2.04 0.48
49 INT196424 Binding of Ccnd1 5 0.29 3.34 0.47
50 INT93400 Negative_regulation of Ccnd1 4 0.33 0.77 0.47
51 INT158643 Negative_regulation of Negative_regulation of CCND1 2 0.31 2.43 0.45
52 INT288540 Negative_regulation of Binding of Gsk3b 4 0.53 2.12 0.43
53 INT208552 Negative_regulation of Negative_regulation of Gsk3b 3 0.31 1.8 0.43
54 INT235064 Regulation of Positive_regulation of Gsk3b 3 0.41 1.5 0.42
55 INT204012 Regulation of Negative_regulation of Gsk3b 4 0.42 4.51 0.39
56 INT208538 Regulation of Phosphorylation of Gsk3b 3 0.49 4.49 0.38
57 INT66364 Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
58 INT268620 Regulation of Localization of Gsk3b 3 0.35 2.12 0.28
59 INT186057 Binding of CCND1 8 0.31 5.92 0.26
60 INT113989 Regulation of Gene_expression of CCND1 11 0.44 7.57 0.24
61 INT345254 Positive_regulation of Localization of Gsk3b 2 0.01 0.91 0.24
62 INT341554 Gene_expression of CCNF 1 0.39 0.67 0.24
63 INT204021 Transcription of Gsk3b 8 0.57 2.75 0.23
64 INT268621 Positive_regulation of Localization of Gsk3b 4 0.40 1.54 0.22
65 INT116647 Positive_regulation of Phosphorylation of Gsk3b 1 0.37 0.18 0.22
66 INT341545 Negative_regulation of Gene_expression of CCNF 1 0.22 0.62 0.21
67 INT146801 Regulation of Ccnd1 5 0.34 2.4 0.19
68 INT145248 Negative_regulation of Negative_regulation of Ccnd1 1 0.23 0.47 0.13
69 INT196428 Negative_regulation of Binding of Ccnd1 1 0.14 1.17 0.13
70 INT196427 Negative_regulation of Transcription of Ccnd1 1 0.14 1.17 0.12
71 INT169908 Localization of Ccnd1 7 0.57 2.68 0.11
72 INT268617 Negative_regulation of Regulation of Gsk3b 3 0.28 1.84 0.11
73 INT341552 Positive_regulation of Gene_expression of CCNF 1 0.25 0.25 0.11
74 INT184473 Regulation of Gene_expression of Ccnd1 5 0.40 2.73 0.1
75 INT309869 Regulation of Binding of Gsk3b 1 0.12 0.66 0.1
76 INT312871 Positive_regulation of Transcription of Gsk3b 2 0.29 0.15 0.09
77 INT215750 Transcription of Ccnd1 2 0.14 2.23 0.09
78 INT234926 Protein_catabolism of Gsk3b 2 0.58 1.33 0.08
79 INT234906 Positive_regulation of Protein_catabolism of Gsk3b 2 0.33 1.33 0.08
80 INT145375 Transcription of CCND1 7 0.52 3.86 0.07
81 INT341561 Regulation of Gene_expression of CCNF 1 0.23 0.19 0.07
82 INT167444 Localization of CCNF 1 0.73 0.28 0.07
83 INT215731 Positive_regulation of Transcription of Ccnd1 1 0.13 0.1 0.06
84 INT176590 Positive_regulation of Transcription of CCND1 1 0.17 0.27 0.05
85 INT336062 Regulation of Localization of Gsk3b 1 0.03 0.48 0.04
86 INT221830 Negative_regulation of Transcription of CCND1 3 0.18 2.15 0.03
87 INT203608 Negative_regulation of CCNF 2 0.35 0.44 0.03
88 INT203609 Binding of CCNF 1 0.08 0.32 0.03
89 INT203613 Positive_regulation of Negative_regulation of CCNF 1 0.10 0.33 0.03
90 INT225226 Positive_regulation of Negative_regulation of Ccnd1 1 0.14 1.18 0.03
91 INT258832 Regulation of Transcription of Ccnd1 1 0.16 1.57 0.03
92 INT268625 Regulation of Transcription of Gsk3b 2 0.15 0 0
93 INT215727 Regulation of Gene_expression of Ccnd1 2 0.12 0.49 0
94 INT225215 Negative_regulation of Positive_regulation of Ccnd1 2 0.13 1.33 0
95 INT236700 Phosphorylation of Ccnd1 2 0.18 1.89 0
96 INT225220 Positive_regulation of Positive_regulation of Ccnd1 1 0.14 1.2 0
97 INT305634 Localization of CCND1 1 0.07 2.69 0
98 INT276362 Protein_catabolism of CCND1 1 0.10 0.66 0
99 INT297265 Positive_regulation of Positive_regulation of CCND1 1 0.07 0.94 0
100 INT330350 Positive_regulation of Negative_regulation of CCND1 1 0.08 1.3 0
101 INT268441 Regulation of Regulation of Gsk3b 1 0.07 0.72 0
102 INT235459 Positive_regulation of Protein_catabolism of Ccnd1 1 0.13 0.49 0
103 INT276346 Regulation of Protein_catabolism of CCND1 1 0.04 0.66 0
104 INT260480 Transcription of Gsk3b 1 0.02 3.08 0
105 INT269909 Positive_regulation of Localization of Ccnd1 1 0.38 0 0
106 INT228997 Phosphorylation of Ccnd1 1 0.10 0.52 0
107 INT152449 Regulation of Protein_catabolism of Gsk3b 1 0.12 0.49 0
108 INT302232 Negative_regulation of Binding of CCND1 1 0.11 0.84 0
109 INT152451 Regulation of Gene_expression of Gsk3b 1 0.12 0.57 0
110 INT152448 Protein_catabolism of Gsk3b 1 0.28 0.49 0
111 INT235458 Protein_catabolism of Ccnd1 1 0.19 0.24 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox