GO:0000578

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Name embryonic axis specification
Categary Process
Go Slim No
Go Link GO:0000578
Unique Molecular Interactions 30
Total Molecular Interactions 34
Total Single Events 277
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for embryonic axis specification. They are ordered first by their pain relevance and then by number of times they were reported for embryonic axis specification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT228055 WNT1 Positive_regulation of CTNND2 1 0.54 1.75 0.42
2 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
3 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
4 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
5 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
6 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1
7 INT287879 Binding of WNT5A and FZD5 1 0.06 1.16 0.08
8 INT149222 Binding of Fzd5 and Suds3 1 0.02 0.44 0.07
9 INT233502 Fzd5 Positive_regulation of Gene_expression of Il12a 1 0.04 0.33 0.07
10 INT287877 WNT1 Positive_regulation of Localization of WISP1 1 0.03 0.56 0.05
11 INT287889 WNT1 Positive_regulation of KRT20 1 0.00 0.56 0.05
12 INT343744 mn Negative_regulation of Regulation of Wnt7a 1 0.01 0.1 0
13 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
14 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
15 INT289099 KCNA1 Positive_regulation of Gene_expression of FZD5 1 0.00 0.84 0
16 INT286566 Binding of Ctnnb1 and Cdh6 1 0.00 1 0
17 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0
18 INT136693 Gtf3a Positive_regulation of Ctnnb1 1 0.05 0 0
19 INT311656 Binding of Wnt1 and Spry1 1 0.30 0.39 0
20 INT268521 Binding of WNT1 and MIR221 1 0.02 1.36 0
21 INT297855 Binding of Ndp and Wnt1 1 0.38 1.18 0
22 INT220821 Binding of MAX and Ctnnb1 1 0.09 0.13 0
23 INT286561 Binding of Ctnnb1 and Cdh2 1 0.00 1.06 0
24 INT286567 Prkd1 Regulation of Ctnnb1 1 0.01 0.39 0
25 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for embryonic axis specification. They are ordered first by their pain relevance and then by number of times they were reported in embryonic axis specification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
2 INT55090 Positive_regulation of Wnt7a 13 0.37 2.25 2.2
3 INT141833 Gene_expression of WNT1 14 0.75 10.57 2.1
4 INT29035 Negative_regulation of Wnt1 3 0.41 1.47 2
5 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
6 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
7 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
8 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
9 INT141834 Negative_regulation of Gene_expression of WNT1 3 0.57 1.31 1.2
10 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
11 INT127647 Regulation of Wnt7a 3 0.07 1.28 1.01
12 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
13 INT141835 Negative_regulation of WNT1 2 0.41 1.02 0.83
14 INT202628 Gene_expression of Wnt1 20 0.67 9.2 0.82
15 INT28958 Negative_regulation of Wnt7a 3 0.45 0.49 0.65
16 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
17 INT127648 Gene_expression of Wnt7a 2 0.13 1.11 0.56
18 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
19 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
20 INT228057 Positive_regulation of WNT1 1 0.49 1.8 0.44
21 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
22 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
23 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
24 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
25 INT216379 Positive_regulation of Gene_expression of WNT1 5 0.30 3.1 0.34
26 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
27 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
28 INT353965 Negative_regulation of Gene_expression of Wnt1 1 0.41 0 0.18
29 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
30 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
31 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
32 INT55089 Positive_regulation of Positive_regulation of Wnt7a 2 0.27 0.06 0.16
33 INT217569 Binding of Wnt1 2 0.36 1.07 0.15
34 INT130374 Transcription of Ctnnb1 1 0.19 0 0.13
35 INT266241 Regulation of Wnt1 1 0.26 0.59 0.09
36 INT159426 Positive_regulation of Gene_expression of Wnt7a 1 0.10 0.51 0.05
37 INT304937 Transcription of Wnt1 1 0.22 0.65 0.05
38 INT287946 Positive_regulation of Gene_expression of FZD5 2 0.20 1.69 0.04
39 INT287956 Regulation of WNT1 2 0.26 2.38 0.04
40 INT311648 Regulation of Gene_expression of Wnt1 1 0.39 0.09 0.04
41 INT287936 Regulation of Gene_expression of WNT1 1 0.20 1.06 0.04
42 INT287941 Gene_expression of FZD5 2 0.23 2.94 0.03
43 INT202633 Positive_regulation of Gene_expression of Wnt1 3 0.43 0.85 0
44 INT76959 Binding of Ctnnb1 2 0.34 0.69 0
45 INT289120 Regulation of Gene_expression of FZD5 1 0.13 0.33 0
46 INT230651 Phosphorylation of Ctnnb1 1 0.10 0 0
47 INT230674 Positive_regulation of Phosphorylation of Ctnnb1 1 0.06 0 0
48 INT326137 Protein_catabolism of Ctnnb1 1 0.02 1.08 0
49 INT266460 Positive_regulation of Binding of Wnt7a 1 0.04 0.06 0
50 INT355576 Negative_regulation of Negative_regulation of Ctnnb1 1 0.02 1.14 0
51 INT337424 Phosphorylation of Wnt1 1 0.79 0 0
52 INT220769 Positive_regulation of Positive_regulation of Ctnnb1 1 0.10 0 0
53 INT266459 Binding of Wnt7a 1 0.03 0.06 0
54 INT311632 Positive_regulation of Wnt1 1 0.43 0.19 0
55 INT235058 Localization of Wnt1 1 0.64 0.56 0
56 INT289131 Negative_regulation of Gene_expression of FZD5 1 0.13 0.69 0
57 INT343743 Negative_regulation of Regulation of Wnt7a 1 0.04 0.1 0
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