GO:0000776

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Name kinetochore
Categary Component
Go Slim No
Go Link GO:0000776
Unique Molecular Interactions 328
Total Molecular Interactions 460
Total Single Events 2663
Pain Genes Associated 35

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for kinetochore. They are ordered first by their pain relevance and then by number of times they were reported for kinetochore. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT229497 Binding of Vim and Ndel1 1 0.33 3.5 2.81
2 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
3 INT229496 Binding of Ndel1 and Gopc 1 0.08 2.05 1.36
4 INT136200 Binding of Penk and NUP37 1 0.04 0 1.28
5 INT100816 PPP1R14C Regulation of Ppp1cc 1 0.08 0 1.27
6 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
7 INT340439 Binding of HLA-DMA and SUGT1 1 0.00 4.1 1.16
8 INT196812 Ppp1r1b Negative_regulation of Ppp1cc 3 0.07 0.13 1.12
9 INT109374 Ppp1cc Negative_regulation of Ppp2r1a 1 0.24 0 1.11
10 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04
11 INT164364 Binding of DRD2 and SUGT1 2 0.06 0.33 0.77
12 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
13 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73
14 INT134652 Binding of MC1R and SUGT1 1 0.02 0.84 0.68
15 INT100806 Ppp1r14a Regulation of Ppp1cc 1 0.05 0 0.65
16 INT218837 Ppp1cc Regulation of Ltp 1 0.13 1.19 0.62
17 INT218835 Ppp1cc Regulation of Cysltr1 1 0.01 1.19 0.62
18 INT218833 Binding of Ppp1cc and Regulation of Ltp 1 0.13 1.2 0.62
19 INT218836 Binding of Ppp1cc and Regulation of Cysltr1 1 0.01 1.2 0.62
20 INT218845 Ppp1cc Positive_regulation of Positive_regulation of Cysltr1 1 0.02 0.92 0.6
21 INT159125 Binding of OPRM1 and SUGT1 1 0.03 0.31 0.57
22 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55
23 INT196809 Arpp21 Regulation of Ppp1cc 1 0.01 0 0.52
24 INT292075 FSCN1 Positive_regulation of Gene_expression of Csnk1a1 1 0.03 0.57 0.52
25 INT196826 Ppp1r1b Regulation of Ppp1cc 1 0.10 0 0.51
26 INT251730 Binding of CD70 and SUGT1 1 0.01 0.85 0.49
27 INT182150 Binding of APC and DCPS 1 0.02 1.14 0.48
28 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 0.03 0.96 0.48
29 INT231713 Binding of SUGT1 and GPR174 1 0.00 0.82 0.47
30 INT231340 INCENP Regulation of Gene_expression of IL6 1 0.01 1.09 0.47
31 INT177794 BUB1B Positive_regulation of Gene_expression of ASNS 1 0.11 0.77 0.46
32 INT177781 BUB1B Positive_regulation of ATF4 1 0.07 0.76 0.46
33 INT177780 BUB1B Positive_regulation of ASNS 1 0.05 0.76 0.46
34 INT177787 BUB1B Positive_regulation of MTHFD2 1 0.15 0.76 0.46
35 INT229507 Binding of Nefl and Ndel1 1 0.09 2.01 0.43
36 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
37 INT196800 Trh Negative_regulation of Ppp1cc 1 0.01 0 0.39
38 INT196829 Ppp1r1b Negative_regulation of Phosphorylation of Ppp1cc 1 0.07 0 0.39
39 INT256321 INCENP Positive_regulation of Gene_expression of Vcam1 1 0.00 1.89 0.38
40 INT299788 INCENP Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37
41 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
42 INT218843 Binding of Ppp1cc and Ppp1r9a 1 0.17 0.52 0.36
43 INT278749 NUP98 Positive_regulation of Gene_expression of PTGS2 1 0.46 1.28 0.35
44 INT280479 Binding of Mecp2 and Sin3a 1 0.00 1.54 0.35
45 INT196820 Negative_regulation of Ppp1cc Positive_regulation of Akt1 1 0.00 0 0.34
46 INT341794 Binding of SUGT1 and CEP68 1 0.00 1.1 0.33
47 INT195665 APC Negative_regulation of F8 1 0.04 1.53 0.32
48 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
49 INT195664 APC Negative_regulation of F5 1 0.08 1.51 0.31
50 INT63122 Binding of APC and Man2a2 1 0.01 0.15 0.3
51 INT218831 Ppp1cc Regulation of Gria2 1 0.27 0.86 0.3
52 INT226375 INCENP Positive_regulation of Regulation of TH1L 1 0.01 0.57 0.29
53 INT226376 INCENP Negative_regulation of Gene_expression of TH1L 1 0.00 0.61 0.29
54 INT218847 Ppp1cc Positive_regulation of Regulation of Ltp 1 0.22 0.46 0.29
55 INT289954 Binding of APC and CD28 1 0.03 0.38 0.28
56 INT226383 IL22 Positive_regulation of Gene_expression of INCENP 1 0.00 0.85 0.28
57 INT329528 Seh1l Positive_regulation of Gene_expression of Csf2 1 0.07 0.37 0.28
58 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
59 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27
60 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 0.01 0.72 0.26
61 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
62 INT261976 Binding of PDCD1 and SUGT1 1 0.00 1.3 0.25
63 INT302169 PTGER2 Positive_regulation of DYNC1LI1 1 0.02 1.51 0.25
64 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24
65 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24
66 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24
67 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24
68 INT109408 Negative_regulation of APC Negative_regulation of Positive_regulation of RASGRP1 1 0.06 0.73 0.23
69 INT252213 INCENP Regulation of Lgals3 1 0.00 1.91 0.23
70 INT183945 INCENP Positive_regulation of Localization of IL6 1 0.00 0.2 0.23
71 INT250783 APC Negative_regulation of SERPINE1 1 0.06 0.86 0.23
72 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23
73 INT250553 Binding of RS1 and SUGT1 3 0.00 3.36 0.22
74 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22
75 INT90280 Binding of Ppp1cc and Ppp2ca 1 0.34 0.22 0.22
76 INT195663 APC Negative_regulation of Gene_expression of IL6 1 0.16 1.18 0.22
77 INT52355 Cfp Negative_regulation of Ndel1 1 0.34 0.16 0.21
78 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2
79 INT226384 INCENP Positive_regulation of IL19 1 0.00 0.58 0.2
80 INT229513 Positive_regulation of Binding of Ndel1 and Gopc 1 0.09 0.2 0.2
81 INT265048 INCENP Positive_regulation of Positive_regulation of Nfasc 1 0.00 0.69 0.19
82 INT280487 Negative_regulation of Binding of Mecp2 and Sin3a 1 0.00 0.77 0.18
83 INT226372 INCENP Negative_regulation of Gene_expression of IL5 1 0.00 1.12 0.18
84 INT231866 INCENP Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18
85 INT262359 Binding of DISC1 and NDEL1 1 0.04 0.56 0.18
86 INT334106 APC Negative_regulation of NFKB1 1 0.25 1.37 0.17
87 INT222443 INCENP Positive_regulation of Localization of Pomc 1 0.00 0.75 0.17
88 INT334108 APC Negative_regulation of TNF 1 0.13 1.36 0.17
89 INT178336 Binding of SUGT1 and Chdh 1 0.00 0.98 0.17
90 INT341813 Binding of SUGT1 and Aia1 1 0.00 0.48 0.16
91 INT118257 Binding of ENPP1 and SUGT1 1 0.00 0.87 0.16
92 INT226367 INCENP Negative_regulation of SOCS1 1 0.01 0.47 0.15
93 INT295336 Binding of Grb7 and Xpo1 1 0.09 0.31 0.15
94 INT295342 Binding of Hua and Xpo1 1 0.06 0.31 0.15
95 INT343833 INCENP Positive_regulation of TLR4 1 0.01 0.92 0.14
96 INT343840 Protein_catabolism of INCENP Positive_regulation of TLR4 1 0.01 0.92 0.14
97 INT94763 PSEN2 Regulation of Positive_regulation of App 1 0.11 0.72 0.14
98 INT226378 INCENP Positive_regulation of Transcription of SOCS1 1 0.01 0.41 0.13
99 INT289956 Binding of APC and ICAM1 1 0.04 0.5 0.13
100 INT242163 Wnt2 Positive_regulation of Regulation of Apc 1 0.13 0.71 0.13
101 INT184603 APC Negative_regulation of Gene_expression of TNF 1 0.09 0.97 0.13
102 INT276037 Binding of Prkaca and Ppp1cc 1 0.08 0 0.12
103 INT276040 Binding of Camk2a and Ppp1cc 1 0.13 0 0.12
104 INT316190 Apc Negative_regulation of Positive_regulation of Mapk1 1 0.33 0.66 0.12
105 INT210161 INCENP Positive_regulation of TNFRSF8 1 0.02 0.93 0.12
106 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
107 INT184608 APC Regulation of Gene_expression of Nppa 1 0.06 1.11 0.12
108 INT299754 Binding of APC and CTLA4 2 0.08 0.97 0.11
109 INT171383 Ppp1cc Positive_regulation of Positive_regulation of Mapk1 1 0.18 0 0.11
110 INT298829 Binding of LCT and SUGT1 1 0.00 0.39 0.11
111 INT235385 INCENP Negative_regulation of Bche 1 0.01 0.19 0.11
112 INT171385 Ppp1cc Positive_regulation of Phosphorylation of Egfr 1 0.15 0 0.11
113 INT171387 Ppp1cc Positive_regulation of Phosphorylation of Src 1 0.07 0 0.11
114 INT171392 Ppp1cc Positive_regulation of Phosphorylation of Gpbar1 1 0.06 0 0.11
115 INT2993 Binding of HLA-B and SUGT1 1 0.00 0.6 0.1
116 INT262255 Binding of APC and F2R 1 0.05 3 0.1
117 INT229506 Negative_regulation of Binding of Ndel1 and Gopc 1 0.08 0.35 0.09
118 INT222442 Tlr4 Positive_regulation of Gene_expression of INCENP 1 0.00 0.34 0.09
119 INT267156 Binding of VDR and SUGT1 1 0.04 3.4 0.09
120 INT229504 Negative_regulation of Binding of Nefl and Ndel1 1 0.08 0.33 0.09
121 INT276033 Binding of Ppp1cc and Ppp1r1b 1 0.06 0 0.09
122 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
123 INT270203 Binding of CD28 and Apc 1 0.04 0.58 0.08
124 INT173058 INCENP Positive_regulation of Gene_expression of VEGFA 1 0.03 1.48 0.08
125 INT193959 Psen1 Regulation of App 1 0.40 0.58 0.08
126 INT267154 ADIPOQ Regulation of Positive_regulation of SUGT1 1 0.03 1.18 0.08
127 INT222662 Il1a Positive_regulation of Gene_expression of INCENP 1 0.00 0.32 0.08
128 INT257777 INCENP Positive_regulation of AR 1 0.04 0.49 0.08
129 INT186712 INCENP Positive_regulation of PPARA 1 0.01 1.05 0.08
130 INT270197 Binding of Apc and Cd86 1 0.02 0.58 0.08
131 INT294220 INCENP Positive_regulation of Gene_expression of Serpine1 1 0.00 0.41 0.08
132 INT294218 INCENP Positive_regulation of Plat 1 0.00 0.4 0.08
133 INT270198 Binding of Apc and Cd80 1 0.02 0.58 0.08
134 INT218834 Ppp1cc Regulation of Phosphorylation of Gria1 1 0.19 0.66 0.07
135 INT229500 Binding of Vim and Nde1 1 0.00 0.79 0.07
136 INT218829 Ppp1cc Regulation of Phosphorylation of Gria1 1 0.20 0.63 0.07
137 INT268675 Binding of NCOR2 and SIN3A 1 0.27 2.54 0.07
138 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06
139 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
140 INT229493 Binding of Ndel1 and Disc1 1 0.13 0.68 0.06
141 INT335711 INCENP Positive_regulation of Gene_expression of FAS 1 0.04 1.42 0.06
142 INT260565 T2dm2 Regulation of SUGT1 1 0.00 1.43 0.05
143 INT176095 Binding of Apc and EC 1 0.04 0.51 0.05
144 INT306510 INCENP Regulation of Gene_expression of Clu 1 0.00 1.92 0.05
145 INT327822 INCENP Regulation of Gene_expression of Lep 1 0.00 0.5 0.05
146 INT193967 Binding of PSEN1 and Psen1 1 0.41 1.2 0.05
147 INT193970 Binding of PSEN1 and Psen2 1 0.36 2.06 0.05
148 INT267153 Binding of LEP and SUGT1 1 0.02 0.69 0.05
149 INT120574 Binding of Apc and Egfr 1 0.27 1.02 0.05
150 INT334107 Binding of APC and APCS 1 0.16 1.52 0.04
151 INT229499 Nde1 Regulation of Vim 1 0.00 0.35 0.04
152 INT267155 Binding of INS and SUGT1 1 0.02 0.81 0.04
153 INT229505 Ndel1 Negative_regulation of Vim 1 0.29 0.14 0.04
154 INT343540 Binding of PPP1R12A and MLC1 1 0.09 0.15 0.04
155 INT322671 Binding of Gfm1 and Pbrm1 1 0.00 0.96 0.04
156 INT356101 App Regulation of Negative_regulation of Psen1 1 0.23 0.31 0.04
157 INT213392 Binding of SELPLG and XPO1 1 0.02 0.31 0.04
158 INT229494 Binding of Ndel1 and Tsp1 1 0.03 0.24 0.04
159 INT331477 PSEN2 Regulation of Gene_expression of Psen1 1 0.00 0.15 0.03
160 INT354896 Binding of Psen2 and Fancd2 1 0.04 0.75 0.03
161 INT173612 FGFR1 Positive_regulation of INCENP 1 0.00 0.28 0.03
162 INT173613 BMP2 Positive_regulation of INCENP 1 0.00 0.28 0.03
163 INT318191 INCENP Negative_regulation of Gene_expression of VEGFA 1 0.00 1.05 0.03
164 INT322667 Binding of Vdac1 and Pbrm1 1 0.15 0.79 0.03
165 INT229503 Binding of Ndel1 and Fez1 1 0.15 0.34 0.03
166 INT300179 Binding of BGLAP and INCENP 1 0.02 0.08 0.03
167 INT331478 Psen1 Regulation of Gene_expression of PSEN2 1 0.00 0.15 0.03
168 INT183757 INCENP Negative_regulation of Transcription of CXCR4 1 0.01 0.93 0.03
169 INT322672 Binding of SLC25A6 and Pbrm1 1 0.04 1.87 0.03
170 INT318187 Binding of INCENP and MUC5AC 1 0.00 1.03 0.03
171 INT183758 INCENP Negative_regulation of Transcription of CCR5 1 0.00 0.93 0.03
172 INT231862 F2 Positive_regulation of INCENP 1 0.00 0.86 0.03
173 INT289626 Binding of SNRNP70 and SUGT1 3 0.03 2.49 0
174 INT244026 Ppp1cc Regulation of Phosphorylation of Camk2a 1 0.03 0 0
175 INT295338 Ptpn11 Regulation of Binding of Xpo1 1 0.02 0 0
176 INT192046 Negative_regulation of Binding of RYR2 and Cbx5 1 0.01 1.12 0
177 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
178 INT213034 Hdl1 Positive_regulation of Apc 1 0.08 1.21 0
179 INT279515 Daf2 Negative_regulation of INCENP 1 0.00 0 0
180 INT343999 INCENP Positive_regulation of BMP2 1 0.01 0 0
181 INT278768 NUP98 Negative_regulation of Gene_expression of RAP1A 1 0.41 0.44 0
182 INT350523 ABL1 Negative_regulation of Pmf1 1 0.01 2.19 0
183 INT295344 Regulation of Binding of Hua and Xpo1 1 0.05 0 0
184 INT330697 PCNA Regulation of INCENP 1 0.00 0.3 0
185 INT341502 Negative_regulation of Binding of Apc and Pdcd1 1 0.00 0.53 0
186 INT193962 Binding of Psen1 and Ncstn 1 0.13 0.08 0
187 INT229511 Ndel1 Regulation of Binding of Nefl 1 0.09 0.31 0
188 INT334644 Binding of PSEN1 and TTN 1 0.01 0 0
189 INT276044 Binding of Pde1b and Ppp1cc 1 0.12 0 0
190 INT350098 Gene_expression of PSEN2 Positive_regulation of Gene_expression of Hmox1 1 0.39 0 0
191 INT295408 Binding of Oprk1 and Xpo1 1 0.00 0 0
192 INT278772 NUP98 Regulation of HOXA9 1 0.42 0 0
193 INT275123 Binding of HLA-E and SUGT1 1 0.00 0.93 0
194 INT273289 Binding of Psen2 and Ryr2 1 0.27 4.53 0
195 INT278765 Binding of RUNX1 and NUP98 1 0.02 0.26 0
196 INT239080 Binding of PPY and KAT2B 1 0.02 2.38 0
197 INT331118 Regulation of Binding of KIF22 and EBNA1BP2 1 0.04 0.16 0
198 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0
199 INT278755 OR51S1 Regulation of NUP98 1 0.00 0 0
200 INT191096 Negative_regulation of Binding of Apc and Esr1 1 0.05 1.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for kinetochore. They are ordered first by their pain relevance and then by number of times they were reported in kinetochore. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT292049 Gene_expression of Csnk1a1 1 0.59 28.22 19.53
2 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
3 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31
4 INT3002 Binding of SUGT1 62 0.24 55.9 14.91
5 INT174838 Localization of INCENP 80 0.64 19.05 12.89
6 INT57057 Gene_expression of APC 131 0.78 122.24 8.7
7 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
8 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11
9 INT90275 Negative_regulation of Ppp1cc 29 0.58 1.91 7.11
10 INT173639 Positive_regulation of INCENP 40 0.14 20.97 6.7
11 INT8101 Binding of INCENP 42 0.31 16.2 6.68
12 INT292062 Negative_regulation of Csnk1a1 1 0.44 7.57 6.52
13 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
14 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
15 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
16 INT84909 Positive_regulation of SUGT1 22 0.08 22.01 5.43
17 INT292072 Positive_regulation of Gene_expression of Csnk1a1 1 0.53 9.76 5.39
18 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
19 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08
20 INT292060 Positive_regulation of Csnk1a1 1 0.53 6.03 4.57
21 INT84911 Gene_expression of SUGT1 43 0.11 19.85 4.54
22 INT292057 Regulation of Csnk1a1 1 0.34 3.52 4.33
23 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
24 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
25 INT63121 Binding of APC 29 0.41 23.02 3.8
26 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
27 INT292056 Localization of Csnk1a1 1 0.57 3.99 3.17
28 INT172551 Negative_regulation of INCENP 38 0.07 20.83 3.14
29 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
30 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
31 INT172177 Protein_catabolism of INCENP 18 0.37 6.34 2.91
32 INT200833 Gene_expression of Ndel1 2 0.73 5.56 2.9
33 INT90276 Gene_expression of Ppp1cc 10 0.73 0.83 2.87
34 INT90273 Positive_regulation of Ppp1cc 10 0.41 0.82 2.71
35 INT98457 Phosphorylation of Ppp1cc 11 0.33 0.12 2.57
36 INT292070 Binding of Csnk1a1 1 0.28 3.18 2.5
37 INT222400 Negative_regulation of Localization of INCENP 4 0.02 1.82 2.46
38 INT322648 Gene_expression of Pbrm1 1 0.62 39.51 2.43
39 INT163544 Binding of Psen1 40 0.36 15.28 2.42
40 INT100805 Binding of Ppp1cc 7 0.47 1.77 2.23
41 INT173090 Regulation of INCENP 24 0.09 9.45 2.16
42 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
43 INT60723 Localization of Psen2 5 0.68 2.11 2.02
44 INT229467 Binding of Ndel1 1 0.45 2.71 2
45 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
46 INT181280 Regulation of Gene_expression of INCENP 5 0.07 4 1.78
47 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
48 INT257820 Positive_regulation of PAFAH1B1 1 0.68 11.09 1.69
49 INT3818 Regulation of Apc 13 0.39 12.52 1.68
50 INT229463 Positive_regulation of Ndel1 1 0.66 1.87 1.64
51 INT292052 Regulation of Gene_expression of Csnk1a1 1 0.47 2.5 1.62
52 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
53 INT54996 Regulation of KAT2B 1 0.19 0.38 1.45
54 INT78646 Regulation of Psen2 4 0.20 1.78 1.42
55 INT140858 Negative_regulation of SUGT1 9 0.05 8.41 1.4
56 INT220177 Binding of Apc 21 0.37 15.34 1.37
57 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
58 INT171975 Negative_regulation of Gene_expression of INCENP 8 0.05 5.24 1.35
59 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
60 INT173877 Positive_regulation of Gene_expression of INCENP 14 0.08 7.83 1.28
61 INT329510 Gene_expression of Seh1l 1 0.67 2.95 1.18
62 INT102073 Regulation of Gene_expression of APC 5 0.45 6.09 1.15
63 INT102074 Positive_regulation of Gene_expression of APC 20 0.50 13.66 1.1
64 INT229466 Localization of Ndel1 1 0.76 1.32 1.1
65 INT292071 Regulation of Negative_regulation of Csnk1a1 1 0.34 0.64 1.07
66 INT78645 Negative_regulation of Gene_expression of Psen2 1 0.14 0.13 1.01
67 INT257824 Localization of PAFAH1B1 1 0.74 6.58 1
68 INT292066 Negative_regulation of Gene_expression of Csnk1a1 1 0.32 2.01 0.95
69 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
70 INT292067 Negative_regulation of Negative_regulation of Csnk1a1 1 0.32 0.56 0.9
71 INT292063 Positive_regulation of Positive_regulation of Csnk1a1 1 0.38 1.46 0.9
72 INT242134 Localization of Apc 8 0.74 4.83 0.88
73 INT78647 Positive_regulation of Localization of Psen2 1 0.16 0.14 0.83
74 INT292048 Transcription of Csnk1a1 1 0.52 1.44 0.82
75 INT159126 Localization of SUGT1 3 0.06 1.76 0.81
76 INT95190 Gene_expression of NDEL1 1 0.29 0 0.81
77 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
78 INT94756 Positive_regulation of PSEN2 8 0.49 4.59 0.77
79 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
80 INT193849 Positive_regulation of Gene_expression of Psen2 5 0.44 4.92 0.76
81 INT196741 Positive_regulation of Negative_regulation of Ppp1cc 3 0.33 0.42 0.76
82 INT180752 Gene_expression of PAFAH1B1 3 0.66 9.89 0.75
83 INT144540 Negative_regulation of Gene_expression of Sin3a 1 0.57 0.85 0.75
84 INT144544 Gene_expression of Sin3a 1 0.75 0.84 0.74
85 INT78649 Binding of Psen2 7 0.36 5.9 0.73
86 INT78648 Regulation of Binding of Psen2 1 0.14 0.2 0.73
87 INT57062 Regulation of APC 24 0.58 14.3 0.7
88 INT257817 Regulation of PAFAH1B1 1 0.60 4.93 0.7
89 INT80674 Negative_regulation of Gene_expression of APC 16 0.59 18.14 0.69
90 INT181282 Transcription of INCENP 10 0.11 1.21 0.66
91 INT91765 Positive_regulation of Gene_expression of PSEN2 8 0.49 4.57 0.63
92 INT196739 Regulation of Ppp1cc 5 0.19 0 0.63
93 INT35943 Positive_regulation of NDEL1 1 0.31 0 0.62
94 INT100804 Regulation of Gene_expression of Ppp1cc 2 0.18 0 0.6
95 INT100803 Regulation of Phosphorylation of Ppp1cc 1 0.10 0 0.57
96 INT72869 Regulation of Negative_regulation of APC 2 0.36 1.7 0.54
97 INT217394 Regulation of Binding of PSEN1 1 0.44 1.58 0.53
98 INT329516 Negative_regulation of Gene_expression of Seh1l 1 0.37 0.42 0.53
99 INT257816 Negative_regulation of PAFAH1B1 1 0.58 3.66 0.49
100 INT35942 Negative_regulation of NDEL1 1 0.27 0 0.47
101 INT229481 Positive_regulation of Gene_expression of Ndel1 1 0.47 0.73 0.47
102 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46
103 INT302917 Binding of Pbrm1 2 0.34 8.06 0.46
104 INT177869 Gene_expression of BUB1B 2 0.65 2.11 0.45
105 INT177866 Negative_regulation of BUB1B 1 0.32 1.23 0.45
106 INT126428 Negative_regulation of Negative_regulation of Ppp1cc 1 0.42 0 0.45
107 INT316041 Transcription of Psen2 1 0.64 1.1 0.45
108 INT177845 Negative_regulation of Gene_expression of BUB1B 1 0.23 0.75 0.45
109 INT234249 Regulation of PSEN1 6 0.37 2.21 0.43
110 INT322637 Negative_regulation of Pbrm1 1 0.30 2.97 0.43
111 INT234257 Regulation of Gene_expression of PSEN1 6 0.44 1.98 0.42
112 INT152151 Regulation of Gene_expression of Apc 4 0.44 3.87 0.42
113 INT193856 Localization of Psen1 19 0.73 9.79 0.41
114 INT329526 Positive_regulation of Seh1l 1 0.43 0.73 0.41
115 INT353342 Positive_regulation of Positive_regulation of INCENP 1 0.01 0.46 0.4
116 INT36396 Positive_regulation of Psen2 6 0.44 4.57 0.39
117 INT95191 Protein_catabolism of NDEL1 1 0.22 0 0.39
118 INT292053 Regulation of Localization of Csnk1a1 1 0.34 0.51 0.38
119 INT239084 Localization of KAT2B 4 0.73 3.08 0.36
120 INT177773 Localization of PSEN1 4 0.73 0.89 0.36
121 INT322646 Regulation of Gene_expression of Pbrm1 1 0.49 2.78 0.36
122 INT220170 Regulation of Positive_regulation of Apc 1 0.10 0.46 0.35
123 INT118243 Transcription of APC 4 0.45 3.33 0.33
124 INT184605 Positive_regulation of Transcription of APC 2 0.19 2.39 0.33
125 INT261682 Positive_regulation of Positive_regulation of PSEN2 1 0.21 0.55 0.33
126 INT225667 Transcription of Apc 3 0.52 3.73 0.32
127 INT222401 Regulation of Localization of INCENP 2 0.01 0.81 0.32
128 INT229482 Positive_regulation of Binding of Ndel1 1 0.47 0.37 0.32
129 INT196732 Localization of Ppp1cc 2 0.30 0 0.31
130 INT195672 Localization of APC 7 0.74 3.76 0.3
131 INT329522 Localization of Seh1l 1 0.64 0.34 0.3
132 INT329514 Regulation of Gene_expression of Seh1l 1 0.39 0.65 0.3
133 INT229459 Negative_regulation of Gene_expression of Ndel1 1 0.41 0.75 0.29
134 INT266973 Negative_regulation of KAT2B 1 0.01 0.99 0.29
135 INT229473 Transcription of Ndel1 1 0.65 0.49 0.29
136 INT292073 Regulation of Positive_regulation of Csnk1a1 1 0.34 0.67 0.29
137 INT224298 Negative_regulation of PSEN2 6 0.57 2.29 0.28
138 INT184629 Negative_regulation of Positive_regulation of INCENP 1 0.05 0.89 0.28
139 INT316045 Negative_regulation of Negative_regulation of Psen1 1 0.42 1.58 0.27
140 INT226431 Phosphorylation of INCENP 3 0.04 3.41 0.26
141 INT292068 Positive_regulation of Binding of Csnk1a1 1 0.38 0.92 0.25
142 INT302243 Positive_regulation of DYNC1LI1 1 0.04 1.42 0.25
143 INT261676 Negative_regulation of Positive_regulation of PSEN1 1 0.36 1.59 0.25
144 INT302262 Negative_regulation of DYNC1LI1 1 0.04 1.36 0.25
145 INT172525 Localization of PSEN2 5 0.73 4.17 0.24
146 INT1475 Localization of CLIP1 1 0.06 0 0.24
147 INT277757 Gene_expression of Pmf1 3 0.12 4.14 0.23
148 INT229476 Regulation of Ndel1 1 0.43 0.6 0.23
149 INT292054 Phosphorylation of Csnk1a1 1 0.54 0.78 0.23
150 INT225666 Regulation of Transcription of Apc 1 0.29 0.33 0.22
151 INT52354 Regulation of Ndel1 1 0.19 0.16 0.21
152 INT196787 Positive_regulation of Localization of Ppp1cc 1 0.20 0 0.21
153 INT52351 Positive_regulation of Ndel1 1 0.50 0.16 0.21
154 INT181508 Regulation of Regulation of Psen1 2 0.33 0.51 0.2
155 INT173166 Negative_regulation of Binding of APC 3 0.40 3.01 0.19
156 INT86687 Gene_expression of Ndel1 1 0.25 0 0.19
157 INT322651 Regulation of Pbrm1 1 0.22 1.04 0.19
158 INT292055 Negative_regulation of Binding of Csnk1a1 1 0.32 0.3 0.18
159 INT262360 Binding of NDEL1 1 0.04 0.56 0.18
160 INT57065 Negative_regulation of Positive_regulation of APC 3 0.22 2.43 0.17
161 INT280465 Negative_regulation of Sin3a 2 0.41 1.07 0.17
162 INT286317 Positive_regulation of Transcription of Psen1 1 0.37 0.32 0.17
163 INT228603 Positive_regulation of Positive_regulation of Apc 1 0.24 0.24 0.17
164 INT257825 Binding of PAFAH1B1 1 0.37 0.89 0.17
165 INT322654 Localization of Pbrm1 1 0.60 7.56 0.16
166 INT257818 Regulation of Gene_expression of PAFAH1B1 1 0.44 0.76 0.15
167 INT196751 Negative_regulation of Phosphorylation of Ppp1cc 1 0.17 0 0.14
168 INT329512 Negative_regulation of Seh1l 1 0.37 0.06 0.14
169 INT257821 Transcription of PAFAH1B1 1 0.61 1.11 0.14
170 INT185754 Negative_regulation of Binding of INCENP 5 0.03 2.01 0.13
171 INT76295 Gene_expression of KIF22 3 0.10 1.29 0.13
172 INT250790 Negative_regulation of Localization of APC 2 0.13 2.3 0.13
173 INT250792 Positive_regulation of Localization of APC 1 0.15 0.48 0.13
174 INT336359 Positive_regulation of Phosphorylation of Psen1 1 0.33 0.4 0.13
175 INT336361 Phosphorylation of Psen1 1 0.54 0.34 0.13
176 INT277821 Positive_regulation of Negative_regulation of INCENP 2 0.03 0.89 0.12
177 INT242140 Regulation of Localization of Apc 1 0.12 0.12 0.11
178 INT176595 Negative_regulation of Gene_expression of PSEN2 1 0.24 1.01 0.11
179 INT193841 Regulation of Gene_expression of Psen2 1 0.40 1.66 0.11
180 INT242819 Negative_regulation of Gene_expression of Apc 4 0.37 5.6 0.1
181 INT201694 Negative_regulation of Gene_expression of PSEN1 3 0.41 2.31 0.1
182 INT42713 Binding of CLIP1 2 0.36 0 0.1
183 INT46301 Positive_regulation of CLIP1 2 0.60 0 0.1
184 INT268372 Phosphorylation of APC 3 0.81 3.39 0.09
185 INT101082 Positive_regulation of KAT2B 1 0.38 0.76 0.09
186 INT240093 Negative_regulation of Transcription of INCENP 1 0.01 0.26 0.09
187 INT239085 Binding of KAT2B 1 0.18 2.04 0.09
188 INT273285 Negative_regulation of Localization of Psen1 1 0.36 0.99 0.09
189 INT267163 Positive_regulation of Gene_expression of SUGT1 1 0.06 1.48 0.09
190 INT221970 Phosphorylation of NDEL1 1 0.12 0.39 0.09
191 INT229472 Positive_regulation of Transcription of Ndel1 1 0.44 0.31 0.09
192 INT213406 Positive_regulation of XPO1 5 0.27 1.19 0.08
193 INT109131 Regulation of PSEN2 3 0.44 0.55 0.08
194 INT193862 Positive_regulation of Positive_regulation of Psen1 3 0.49 0.9 0.08
195 INT193872 Positive_regulation of Localization of Psen1 3 0.49 1.39 0.08
196 INT278803 Gene_expression of NUP98 1 0.72 0.78 0.08
197 INT261678 Positive_regulation of Positive_regulation of PSEN1 1 0.42 0.62 0.08
198 INT193890 Regulation of Positive_regulation of Psen1 1 0.44 0.66 0.08
199 INT193938 Phosphorylation of PSEN1 5 0.79 1.6 0.07
200 INT229469 Gene_expression of Pafah1b1 1 0.15 0.32 0.07
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