GO:0000777

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Name condensed chromosome kinetochore
Categary Component
Go Slim No
Go Link GO:0000777
Unique Molecular Interactions 70
Total Molecular Interactions 74
Total Single Events 581
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for condensed chromosome kinetochore. They are ordered first by their pain relevance and then by number of times they were reported for condensed chromosome kinetochore. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT136200 Binding of Penk and NUP37 1 0.04 0 1.28
2 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55
3 INT231340 INCENP Regulation of Gene_expression of IL6 1 0.01 1.09 0.47
4 INT177794 BUB1B Positive_regulation of Gene_expression of ASNS 1 0.11 0.77 0.46
5 INT177781 BUB1B Positive_regulation of ATF4 1 0.07 0.76 0.46
6 INT177780 BUB1B Positive_regulation of ASNS 1 0.05 0.76 0.46
7 INT177787 BUB1B Positive_regulation of MTHFD2 1 0.15 0.76 0.46
8 INT256321 INCENP Positive_regulation of Gene_expression of Vcam1 1 0.00 1.89 0.38
9 INT299788 INCENP Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37
10 INT226375 INCENP Positive_regulation of Regulation of TH1L 1 0.01 0.57 0.29
11 INT226376 INCENP Negative_regulation of Gene_expression of TH1L 1 0.00 0.61 0.29
12 INT226383 IL22 Positive_regulation of Gene_expression of INCENP 1 0.00 0.85 0.28
13 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
14 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 0.01 0.72 0.26
15 INT302169 PTGER2 Positive_regulation of DYNC1LI1 1 0.02 1.51 0.25
16 INT252213 INCENP Regulation of Lgals3 1 0.00 1.91 0.23
17 INT183945 INCENP Positive_regulation of Localization of IL6 1 0.00 0.2 0.23
18 INT52355 Cfp Negative_regulation of Ndel1 1 0.34 0.16 0.21
19 INT226384 INCENP Positive_regulation of IL19 1 0.00 0.58 0.2
20 INT265048 INCENP Positive_regulation of Positive_regulation of Nfasc 1 0.00 0.69 0.19
21 INT226372 INCENP Negative_regulation of Gene_expression of IL5 1 0.00 1.12 0.18
22 INT231866 INCENP Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18
23 INT262359 Binding of DISC1 and NDEL1 1 0.04 0.56 0.18
24 INT222443 INCENP Positive_regulation of Localization of Pomc 1 0.00 0.75 0.17
25 INT226367 INCENP Negative_regulation of SOCS1 1 0.01 0.47 0.15
26 INT343833 INCENP Positive_regulation of TLR4 1 0.01 0.92 0.14
27 INT343840 Protein_catabolism of INCENP Positive_regulation of TLR4 1 0.01 0.92 0.14
28 INT226378 INCENP Positive_regulation of Transcription of SOCS1 1 0.01 0.41 0.13
29 INT210161 INCENP Positive_regulation of TNFRSF8 1 0.02 0.93 0.12
30 INT235385 INCENP Negative_regulation of Bche 1 0.01 0.19 0.11
31 INT222442 Tlr4 Positive_regulation of Gene_expression of INCENP 1 0.00 0.34 0.09
32 INT173058 INCENP Positive_regulation of Gene_expression of VEGFA 1 0.03 1.48 0.08
33 INT188007 NLRP3 Regulation of Binding of TP53BP1 1 0.28 0.62 0.08
34 INT222662 Il1a Positive_regulation of Gene_expression of INCENP 1 0.00 0.32 0.08
35 INT257777 INCENP Positive_regulation of AR 1 0.04 0.49 0.08
36 INT186712 INCENP Positive_regulation of PPARA 1 0.01 1.05 0.08
37 INT294220 INCENP Positive_regulation of Gene_expression of Serpine1 1 0.00 0.41 0.08
38 INT294218 INCENP Positive_regulation of Plat 1 0.00 0.4 0.08
39 INT335711 INCENP Positive_regulation of Gene_expression of FAS 1 0.04 1.42 0.06
40 INT306510 INCENP Regulation of Gene_expression of Clu 1 0.00 1.92 0.05
41 INT327822 INCENP Regulation of Gene_expression of Lep 1 0.00 0.5 0.05
42 INT188006 NLRP3 Regulation of Gene_expression of TP53BP1 1 0.28 0.36 0.04
43 INT188005 NLRP3 Regulation of TP53BP1 1 0.34 0.3 0.04
44 INT173612 FGFR1 Positive_regulation of INCENP 1 0.00 0.28 0.03
45 INT173613 BMP2 Positive_regulation of INCENP 1 0.00 0.28 0.03
46 INT318191 INCENP Negative_regulation of Gene_expression of VEGFA 1 0.00 1.05 0.03
47 INT300179 Binding of BGLAP and INCENP 1 0.02 0.08 0.03
48 INT183757 INCENP Negative_regulation of Transcription of CXCR4 1 0.01 0.93 0.03
49 INT318187 Binding of INCENP and MUC5AC 1 0.00 1.03 0.03
50 INT183758 INCENP Negative_regulation of Transcription of CCR5 1 0.00 0.93 0.03
51 INT231862 F2 Positive_regulation of INCENP 1 0.00 0.86 0.03
52 INT279515 Daf2 Negative_regulation of INCENP 1 0.00 0 0
53 INT343999 INCENP Positive_regulation of BMP2 1 0.01 0 0
54 INT330697 PCNA Regulation of INCENP 1 0.00 0.3 0
55 INT171600 INCENP Negative_regulation of Lipg 1 0.00 0.38 0
56 INT332136 POGLUT1 Negative_regulation of HJURP 1 0.00 0.06 0
57 INT329101 Binding of CD4 and INCENP 1 0.01 0.11 0
58 INT222665 INCENP Positive_regulation of Localization of Gnrh1 1 0.00 0.09 0
59 INT171601 INCENP Negative_regulation of Lpl 1 0.01 0.38 0
60 INT344001 INCENP Positive_regulation of Gene_expression of BMP2 1 0.01 0 0
61 INT297124 Binding of INCENP and Hephl1 1 0.00 0.17 0
62 INT313653 INCENP Negative_regulation of PLA2G2D 1 0.01 0 0
63 INT220455 BAG6 Regulation of INCENP 1 0.00 0.32 0
64 INT217876 Binding of CSNK1A1 and PER2 1 0.18 0.08 0
65 INT209631 INCENP Negative_regulation of CHRM1 1 0.00 0.43 0
66 INT224993 INCENP Regulation of PDGFB 1 0.00 0 0
67 INT303250 Binding of DYNC1LI1 and Dlgap1 1 0.00 0 0
68 INT255203 Binding of INCENP and Ie 1 0.00 0.77 0
69 INT279514 Cr1l Negative_regulation of INCENP 1 0.00 0 0
70 INT209640 INCENP Negative_regulation of Gene_expression of CHRM1 1 0.00 0.91 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for condensed chromosome kinetochore. They are ordered first by their pain relevance and then by number of times they were reported in condensed chromosome kinetochore. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31
2 INT174838 Localization of INCENP 80 0.64 19.05 12.89
3 INT173639 Positive_regulation of INCENP 40 0.14 20.97 6.7
4 INT8101 Binding of INCENP 42 0.31 16.2 6.68
5 INT172551 Negative_regulation of INCENP 38 0.07 20.83 3.14
6 INT172177 Protein_catabolism of INCENP 18 0.37 6.34 2.91
7 INT222400 Negative_regulation of Localization of INCENP 4 0.02 1.82 2.46
8 INT173090 Regulation of INCENP 24 0.09 9.45 2.16
9 INT106153 Gene_expression of HJURP 5 0.04 2.33 1.85
10 INT181280 Regulation of Gene_expression of INCENP 5 0.07 4 1.78
11 INT171975 Negative_regulation of Gene_expression of INCENP 8 0.05 5.24 1.35
12 INT173877 Positive_regulation of Gene_expression of INCENP 14 0.08 7.83 1.28
13 INT95190 Gene_expression of NDEL1 1 0.29 0 0.81
14 INT181282 Transcription of INCENP 10 0.11 1.21 0.66
15 INT35943 Positive_regulation of NDEL1 1 0.31 0 0.62
16 INT35942 Negative_regulation of NDEL1 1 0.27 0 0.47
17 INT177869 Gene_expression of BUB1B 2 0.65 2.11 0.45
18 INT177866 Negative_regulation of BUB1B 1 0.32 1.23 0.45
19 INT177845 Negative_regulation of Gene_expression of BUB1B 1 0.23 0.75 0.45
20 INT353342 Positive_regulation of Positive_regulation of INCENP 1 0.01 0.46 0.4
21 INT95191 Protein_catabolism of NDEL1 1 0.22 0 0.39
22 INT188016 Gene_expression of TP53BP1 6 0.64 5.54 0.35
23 INT222401 Regulation of Localization of INCENP 2 0.01 0.81 0.32
24 INT184629 Negative_regulation of Positive_regulation of INCENP 1 0.05 0.89 0.28
25 INT226431 Phosphorylation of INCENP 3 0.04 3.41 0.26
26 INT188021 Positive_regulation of TP53BP1 3 0.48 1.33 0.25
27 INT302243 Positive_regulation of DYNC1LI1 1 0.04 1.42 0.25
28 INT302262 Negative_regulation of DYNC1LI1 1 0.04 1.36 0.25
29 INT52354 Regulation of Ndel1 1 0.19 0.16 0.21
30 INT52351 Positive_regulation of Ndel1 1 0.50 0.16 0.21
31 INT86687 Gene_expression of Ndel1 1 0.25 0 0.19
32 INT188019 Negative_regulation of TP53BP1 1 0.48 1.42 0.18
33 INT262360 Binding of NDEL1 1 0.04 0.56 0.18
34 INT185754 Negative_regulation of Binding of INCENP 5 0.03 2.01 0.13
35 INT277821 Positive_regulation of Negative_regulation of INCENP 2 0.03 0.89 0.12
36 INT240093 Negative_regulation of Transcription of INCENP 1 0.01 0.26 0.09
37 INT188013 Phosphorylation of TP53BP1 1 0.78 1.81 0.09
38 INT221970 Phosphorylation of NDEL1 1 0.12 0.39 0.09
39 INT188017 Binding of TP53BP1 1 0.46 1.28 0.08
40 INT188010 Positive_regulation of Gene_expression of TP53BP1 1 0.48 0.43 0.07
41 INT188020 Localization of TP53BP1 1 0.71 0.36 0.06
42 INT217905 Phosphorylation of CSNK1A1 3 0.54 2.14 0.05
43 INT188008 Regulation of TP53BP1 4 0.37 1.1 0.04
44 INT52352 Negative_regulation of Ndel1 1 0.42 0.12 0.03
45 INT188014 Negative_regulation of Phosphorylation of TP53BP1 1 0.40 0.68 0
46 INT230109 Positive_regulation of Gene_expression of BUB1B 1 0.42 0.65 0
47 INT217908 Regulation of CSNK1A1 1 0.26 0.08 0
48 INT188009 Regulation of Regulation of TP53BP1 1 0.37 0.07 0
49 INT181285 Positive_regulation of Transcription of INCENP 1 0.08 0 0
50 INT145367 Negative_regulation of CSNK1A1 1 0.13 0 0
51 INT188012 Regulation of Binding of TP53BP1 1 0.58 0.14 0
52 INT332063 Negative_regulation of HJURP 1 0.01 0.1 0
53 INT217910 Positive_regulation of CSNK1A1 1 0.45 0.09 0
54 INT188015 Negative_regulation of Localization of TP53BP1 1 0.35 0.16 0
55 INT259744 Gene_expression of CSNK1A1 1 0.22 0.23 0
56 INT188011 Negative_regulation of Gene_expression of TP53BP1 1 0.40 0.78 0
57 INT175536 Positive_regulation of Localization of INCENP 1 0.01 0.59 0
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