GO:0000781

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Name chromosome, telomeric region
Categary Component
Go Slim No
Go Link GO:0000781
Unique Molecular Interactions 109
Total Molecular Interactions 164
Total Single Events 1094
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chromosome, telomeric region. They are ordered first by their pain relevance and then by number of times they were reported for chromosome, telomeric region. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
2 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
3 INT206206 Binding of Mcf2l and Obfc1 1 0.02 1.11 0.64
4 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61
5 INT164265 TGM7 Negative_regulation of CDK2 1 0.26 1.08 0.53
6 INT160779 Cps1 Positive_regulation of ATM 1 0.01 0.94 0.53
7 INT189688 PRKCA Regulation of Transcription of TERT 1 0.13 0.2 0.5
8 INT189696 PRKCA Negative_regulation of Negative_regulation of TEP1 1 0.02 0.15 0.5
9 INT189680 PRKCA Negative_regulation of TEP1 1 0.02 0.15 0.5
10 INT189675 Negative_regulation of PRKCA Negative_regulation of TEP1 1 0.02 0.15 0.5
11 INT346325 Sirpa Regulation of Obfc1 1 0.00 0.41 0.48
12 INT314263 Binding of CPOX and PTGES3 1 0.01 1.7 0.44
13 INT262760 Binding of TEP1 and CD163L1 1 0.00 1.65 0.37
14 INT189687 INSRR Negative_regulation of Transcription of TERT 1 0.00 0.24 0.35
15 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
16 INT296372 Binding of IDUA and ACD 1 0.03 2.72 0.23
17 INT120716 Binding of AKT1 and TEP1 1 0.05 0.46 0.21
18 INT68510 Binding of ATM and PRLR 1 0.01 0 0.19
19 INT179158 ATM Regulation of Gene_expression of GOPC 1 0.01 0 0.18
20 INT314269 Binding of PTGES and PTGES3 1 0.12 0.68 0.18
21 INT179163 ATM Regulation of Gene_expression of IL13 1 0.01 0 0.18
22 INT179161 ATM Regulation of Gene_expression of IL6 1 0.02 0 0.18
23 INT179162 ATM Regulation of Gene_expression of IL8 1 0.01 0 0.18
24 INT88410 BMP7 Negative_regulation of CDK2 1 0.35 0 0.14
25 INT285948 IL17A Regulation of Gene_expression of TERT 1 0.00 0.58 0.11
26 INT189702 CHKB Regulation of Gene_expression of TERT 1 0.06 0.55 0.1
27 INT346323 Binding of Gopc and Obfc1 1 0.01 0 0.08
28 INT188007 NLRP3 Regulation of Binding of TP53BP1 1 0.28 0.62 0.08
29 INT285938 IL6 Positive_regulation of Gene_expression of TEP1 1 0.01 1.05 0.07
30 INT88411 Positive_regulation of PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
31 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07
32 INT88408 PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
33 INT189677 CHKB Regulation of Transcription of TERT 1 0.10 1 0.05
34 INT189679 INSRR Regulation of Transcription of TERT 1 0.00 1 0.05
35 INT262781 Birc5 Regulation of TEP1 1 0.00 0.49 0.05
36 INT310727 Binding of DKC1 and TERT 1 0.23 0.91 0.05
37 INT220812 Tert Positive_regulation of Gene_expression of hl 1 0.01 0.14 0.04
38 INT188006 NLRP3 Regulation of Gene_expression of TP53BP1 1 0.28 0.36 0.04
39 INT333852 Binding of Ccna1 and Cdk2 1 0.20 0.48 0.04
40 INT220811 Tert Positive_regulation of Gene_expression of Krt36 1 0.41 0.14 0.04
41 INT188005 NLRP3 Regulation of TP53BP1 1 0.34 0.3 0.04
42 INT220808 Tert Positive_regulation of Gene_expression of Krt31 1 0.43 0.14 0.04
43 INT285944 IL6 Positive_regulation of Gene_expression of TERT 1 0.01 0.36 0.04
44 INT346324 Binding of Erh and Obfc1 1 0.03 0 0.03
45 INT289608 Binding of CDK2 and CCNE2 5 0.06 4.89 0
46 INT219412 CDK2 Regulation of PCNA 1 0.20 0.11 0
47 INT296163 Mcph1 Regulation of Tert 1 0.03 0.19 0
48 INT313307 TERT Positive_regulation of NFE2L2 1 0.01 0 0
49 INT333456 ATM Positive_regulation of CHEK2 1 0.20 0 0
50 INT325156 CDKN1B Negative_regulation of CDK2 1 0.49 0.11 0
51 INT331091 Tert Positive_regulation of Positive_regulation of Cd4 1 0.24 0.76 0
52 INT189703 MZF1 Regulation of TERT 1 0.03 0.46 0
53 INT285941 IL6 Regulation of Gene_expression of TERT 1 0.01 0.12 0
54 INT333446 ATM Positive_regulation of CHEK1 1 0.20 0 0
55 INT333455 ATM Positive_regulation of TP53 1 0.18 0 0
56 INT176288 Binding of Cdk2 and Pcna 1 0.01 0.66 0
57 INT220819 Myc Regulation of Transcription of Tert 1 0.44 0.1 0
58 INT333451 ATM Positive_regulation of Negative_regulation of CHEK1 1 0.14 0 0
59 INT347298 AREG Negative_regulation of TEP1 1 0.00 0.79 0
60 INT220813 Tert Positive_regulation of Terc 1 0.51 0.17 0
61 INT189705 INSRR Negative_regulation of Gene_expression of TERT 1 0.00 0.46 0
62 INT220817 Tert Regulation of hl 1 0.01 0.96 0
63 INT189697 INSRR Regulation of Gene_expression of TERT 1 0.00 0.46 0
64 INT270759 Binding of HSD11B1 and TERT 1 0.07 1.67 0
65 INT330956 Binding of TEP1 and NR1H4 1 0.00 1.07 0
66 INT189690 USF1 Regulation of TERT 1 0.05 0.46 0
67 INT333450 ATM Positive_regulation of Negative_regulation of MDM2 1 0.18 0 0
68 INT333460 ATM Positive_regulation of Negative_regulation of CHEK2 1 0.14 0 0
69 INT219426 CDK2 Regulation of HNF4A 1 0.01 0.11 0
70 INT189669 INSRR Regulation of TERT 1 0.00 0 0
71 INT189685 USF1 Positive_regulation of Transcription of TERT 1 0.05 0.27 0
72 INT189698 CHKB Regulation of TERT 1 0.06 0 0
73 INT189673 BCL2 Positive_regulation of Transcription of TERT 1 0.09 0 0
74 INT314688 Binding of CCNE1 and CDK2 1 0.04 1.41 0
75 INT286574 Gene_expression of Pkd1 Negative_regulation of Cdk2 1 0.10 0.09 0
76 INT189676 CCND3 Regulation of Transcription of TERT 1 0.02 0.06 0
77 INT219413 CDK2 Regulation of SKP2 1 0.23 0.11 0
78 INT295043 Akt1 Positive_regulation of Cdk2 1 0.10 0.93 0
79 INT347292 AREG Negative_regulation of Gene_expression of TERT 1 0.02 0.78 0
80 INT210493 Binding of HGF and TEP1 1 0.01 0.19 0
81 INT189672 Positive_regulation of INSRR Regulation of Transcription of TERT 1 0.00 0.23 0
82 INT189682 CHKB Negative_regulation of Gene_expression of TERT 1 0.10 0.46 0
83 INT220816 Tert Regulation of Myc 1 0.44 0.1 0
84 INT220809 Tert Regulation of Regulation of Myc 1 0.32 0.25 0
85 INT189684 RNF2 Regulation of TERT 1 0.02 0.46 0
86 INT333458 ATM Positive_regulation of MDM2 1 0.25 0 0
87 INT210494 Binding of EGF and TEP1 1 0.02 0.19 0
88 INT330957 Binding of TEP1 and VDR 1 0.01 1.07 0
89 INT78634 ATM Positive_regulation of AGT 1 0.17 0.16 0
90 INT220820 Binding of Myc and Tert 1 0.26 0.19 0
91 INT322544 Binding of CDK2 and Ccne1 1 0.16 0 0
92 INT313302 Regulation of TERT Positive_regulation of SQSTM1 1 0.01 0 0
93 INT322503 Negative_regulation of Binding of CDK2 and CCNE2 1 0.01 0.25 0
94 INT333850 Binding of Ccne1 and Cdk2 1 0.26 0 0
95 INT333459 TP53 Positive_regulation of CHEK1 1 0.09 0 0
96 INT285937 IL6 Regulation of TERT 1 0.01 0.12 0
97 INT313291 TERT Positive_regulation of SQSTM1 1 0.02 0 0
98 INT333452 ATM Positive_regulation of Negative_regulation of TP53 1 0.18 0 0
99 INT252549 ATM Positive_regulation of Positive_regulation of CHEK2 1 0.02 0 0
100 INT286186 Binding of Blm and Fig4 1 0.09 0.34 0
101 INT176287 Cdk2 Positive_regulation of Phosphorylation of Esr1 1 0.05 0.67 0
102 INT219419 CDK2 Regulation of E2F2 1 0.23 0.11 0
103 INT191413 Tert Positive_regulation of Nqo1 1 0.02 0.84 0
104 INT186989 Binding of Akt1 and Tert 1 0.00 0.61 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for chromosome, telomeric region. They are ordered first by their pain relevance and then by number of times they were reported in chromosome, telomeric region. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121496 Gene_expression of TERT 107 0.78 45.6 7.42
2 INT121494 Transcription of TERT 64 0.69 10.03 5.55
3 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39
4 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96
5 INT120717 Positive_regulation of TEP1 50 0.63 27.94 2.81
6 INT77925 Negative_regulation of TEP1 21 0.53 15.23 2.62
7 INT133194 Negative_regulation of TERT 23 0.48 4.01 2.45
8 INT189770 Positive_regulation of Transcription of TERT 1 0.28 1.36 2.14
9 INT189766 Regulation of Transcription of TERT 1 0.25 3.48 1.99
10 INT88412 Positive_regulation of CDK2 17 0.57 8.49 1.66
11 INT86368 Gene_expression of TEP1 31 0.50 16.36 1.63
12 INT147403 Regulation of Gene_expression of TERT 11 0.27 3.45 1.54
13 INT220783 Gene_expression of Tert 39 0.77 12.55 1.49
14 INT129712 Positive_regulation of Gene_expression of TERT 12 0.70 7.3 1.44
15 INT133193 Positive_regulation of TERT 16 0.50 6.43 1.38
16 INT147607 Binding of TERT 16 0.48 12.36 1.31
17 INT189736 Regulation of TERT 22 0.40 3.58 1.29
18 INT38916 Positive_regulation of Tert 3 0.33 1.92 1.28
19 INT139886 Gene_expression of PTGES3 11 0.72 1.5 1.27
20 INT152255 Gene_expression of ATM 14 0.71 12.53 1.26
21 INT133195 Negative_regulation of Transcription of TERT 4 0.42 2.9 1.08
22 INT106735 Phosphorylation of CDK2 11 0.79 4.03 1.02
23 INT71601 Positive_regulation of ACD 11 0.60 6.55 0.9
24 INT189734 Negative_regulation of Gene_expression of TERT 8 0.24 1.84 0.85
25 INT114880 Negative_regulation of Cdk2 7 0.35 3.89 0.77
26 INT164813 Localization of Obfc1 3 0.15 0.36 0.76
27 INT94896 Regulation of TEP1 12 0.39 8.04 0.69
28 INT171747 Gene_expression of ACD 4 0.57 4.44 0.68
29 INT105330 Gene_expression of CDK2 31 0.63 13.7 0.67
30 INT346318 Positive_regulation of Obfc1 1 0.05 0.98 0.66
31 INT114879 Gene_expression of Cdk2 5 0.55 2.33 0.6
32 INT114872 Negative_regulation of Gene_expression of Cdk2 2 0.35 1.21 0.6
33 INT113846 Negative_regulation of Positive_regulation of CDK2 1 0.48 0.39 0.6
34 INT241060 Binding of Obfc1 2 0.04 0.19 0.59
35 INT48212 Binding of ATM 5 0.47 3.89 0.57
36 INT160777 Transcription of CHEK2 1 0.52 1.03 0.57
37 INT160778 Transcription of ATM 1 0.40 1.03 0.57
38 INT84826 Negative_regulation of ACD 6 0.50 4.02 0.55
39 INT160776 Positive_regulation of Positive_regulation of ATM 2 0.43 0.94 0.53
40 INT189756 Positive_regulation of Phosphorylation of TERT 1 0.28 0.2 0.5
41 INT189722 Regulation of Positive_regulation of TEP1 1 0.03 0.2 0.5
42 INT189728 Phosphorylation of TERT 1 0.34 0.2 0.5
43 INT220787 Localization of Tert 5 0.69 0.87 0.49
44 INT189757 Negative_regulation of Gene_expression of TEP1 3 0.05 2.09 0.48
45 INT163285 Negative_regulation of Phosphorylation of CDK2 2 0.32 0.52 0.48
46 INT206204 Gene_expression of Obfc1 2 0.07 0.58 0.45
47 INT139890 Regulation of Gene_expression of PTGES3 2 0.50 0.82 0.43
48 INT346321 Regulation of Obfc1 1 0.03 0 0.4
49 INT315892 Negative_regulation of Binding of ATM 1 0.07 1.41 0.4
50 INT154768 Negative_regulation of ATM 10 0.57 7.05 0.39
51 INT158641 Positive_regulation of CHEK2 5 0.35 4.15 0.37
52 INT189763 Positive_regulation of Transcription of TEP1 1 0.06 0.38 0.36
53 INT188016 Gene_expression of TP53BP1 6 0.64 5.54 0.35
54 INT189760 Negative_regulation of Negative_regulation of TERT 1 0.24 0.11 0.34
55 INT189739 Negative_regulation of Regulation of TERT 1 0.18 0.17 0.32
56 INT96569 Negative_regulation of CHEK1 4 0.32 3.08 0.29
57 INT220770 Binding of Tert 7 0.37 1.09 0.27
58 INT167438 Localization of ATM 3 0.55 1.61 0.27
59 INT220785 Positive_regulation of Tert 15 0.68 6.9 0.25
60 INT188021 Positive_regulation of TP53BP1 3 0.48 1.33 0.25
61 INT158642 Regulation of Positive_regulation of CHEK2 1 0.07 1.27 0.25
62 INT106733 Regulation of CDK2 6 0.44 4.76 0.23
63 INT310797 Positive_regulation of Gene_expression of PTGES3 1 0.17 0.7 0.23
64 INT310800 Positive_regulation of PTGES3 1 0.24 0.7 0.23
65 INT189768 Positive_regulation of Positive_regulation of TEP1 5 0.44 1.56 0.21
66 INT294915 Positive_regulation of Gene_expression of ACD 1 0.43 1.08 0.2
67 INT220777 Positive_regulation of Gene_expression of Tert 9 0.68 2.34 0.18
68 INT188019 Negative_regulation of TP53BP1 1 0.48 1.42 0.18
69 INT189732 Transcription of TEP1 1 0.09 0.19 0.18
70 INT163284 Negative_regulation of Gene_expression of CDK2 5 0.32 1.6 0.16
71 INT220767 Regulation of Tert 1 0.53 1 0.16
72 INT94167 Regulation of CHEK1 1 0.04 1.7 0.16
73 INT176246 Regulation of Cdk2 6 0.30 3.31 0.15
74 INT159148 Localization of ACD 3 0.65 1.28 0.14
75 INT220774 Negative_regulation of Gene_expression of Tert 1 0.58 1.09 0.14
76 INT189761 Positive_regulation of Regulation of TERT 1 0.19 0.14 0.14
77 INT278288 Regulation of Localization of ATM 1 0.09 0.95 0.13
78 INT329187 Positive_regulation of Positive_regulation of ACD 1 0.17 0.69 0.13
79 INT201462 Binding of CDK2 12 0.39 5.2 0.12
80 INT167440 Regulation of ATM 2 0.20 0.68 0.12
81 INT189767 Positive_regulation of Gene_expression of TEP1 4 0.30 1.43 0.11
82 INT178215 Binding of TEP1 2 0.06 1.05 0.11
83 INT186980 Transcription of Tert 1 0.34 0.34 0.11
84 INT186973 Regulation of Transcription of Tert 1 0.21 0.34 0.11
85 INT211717 Gene_expression of CHEK2 13 0.37 2.13 0.1
86 INT294914 Positive_regulation of Localization of ACD 1 0.43 0.53 0.1
87 INT201460 Positive_regulation of Gene_expression of CDK2 5 0.52 2.8 0.09
88 INT169428 Regulation of Gene_expression of CDK2 4 0.46 1.03 0.09
89 INT106732 Regulation of Phosphorylation of CDK2 2 0.44 0.8 0.09
90 INT302272 Localization of CDK2 2 0.30 1.09 0.09
91 INT286183 Regulation of Blm 1 0.36 1.3 0.09
92 INT188013 Phosphorylation of TP53BP1 1 0.78 1.81 0.09
93 INT286184 Gene_expression of Blm 1 0.39 2.16 0.09
94 INT252551 Phosphorylation of CHEK2 4 0.48 4.73 0.08
95 INT210506 Negative_regulation of Positive_regulation of TEP1 3 0.28 1.76 0.08
96 INT252552 Positive_regulation of Phosphorylation of CHEK2 1 0.23 0.26 0.08
97 INT188017 Binding of TP53BP1 1 0.46 1.28 0.08
98 INT220780 Regulation of Gene_expression of Tert 1 0.44 0 0.08
99 INT270857 Protein_catabolism of ACD 1 0.07 0.77 0.07
100 INT188010 Positive_regulation of Gene_expression of TP53BP1 1 0.48 0.43 0.07
101 INT139362 Negative_regulation of CHEK2 2 0.35 1.66 0.06
102 INT139365 Negative_regulation of Negative_regulation of CHEK1 1 0.23 1.67 0.06
103 INT188020 Localization of TP53BP1 1 0.71 0.36 0.06
104 INT139364 Negative_regulation of Negative_regulation of CHEK2 1 0.26 1.67 0.06
105 INT162956 Binding of ACD 3 0.32 3.04 0.05
106 INT189740 Regulation of Gene_expression of TEP1 1 0.06 0.48 0.05
107 INT186977 Gene_expression of Tert 1 0.36 1.49 0.05
108 INT188008 Regulation of TP53BP1 4 0.37 1.1 0.04
109 INT220784 Regulation of Regulation of Tert 1 0.39 0 0.04
110 INT220786 Negative_regulation of Tert 8 0.43 2.55 0.03
111 INT282568 Positive_regulation of Cdk2 6 0.34 2.95 0.03
112 INT201468 Negative_regulation of Binding of CDK2 2 0.17 1.1 0.03
113 INT310796 Transcription of PTGES3 1 0.27 0.05 0.03
114 INT274377 Localization of TERT 3 0.70 0.78 0
115 INT169427 Transcription of CDK2 2 0.09 0.42 0
116 INT242456 Binding of Cdk2 2 0.16 1.29 0
117 INT220792 Transcription of Tert 2 0.71 0.56 0
118 INT89749 Regulation of ACD 2 0.23 0.75 0
119 INT157290 Regulation of Gene_expression of ATM 2 0.44 0.86 0
120 INT223278 Positive_regulation of Binding of TERT 2 0.44 1.35 0
121 INT295036 Positive_regulation of Positive_regulation of Cdk2 2 0.34 0.93 0
122 INT236705 Phosphorylation of Cdk2 2 0.31 1.39 0
123 INT186978 Positive_regulation of Positive_regulation of Tert 1 0.22 0.44 0
124 INT188014 Negative_regulation of Phosphorylation of TP53BP1 1 0.40 0.68 0
125 INT186985 Positive_regulation of Transcription of Tert 1 0.24 0 0
126 INT186976 Binding of Tert 1 0.17 0.55 0
127 INT285901 Regulation of Transcription of CDK2 1 0.03 0.7 0
128 INT347316 Negative_regulation of Binding of TERT 1 0.18 0.26 0
129 INT295035 Negative_regulation of Positive_regulation of Cdk2 1 0.22 0.87 0
130 INT188009 Regulation of Regulation of TP53BP1 1 0.37 0.07 0
131 INT252553 Positive_regulation of Positive_regulation of CHEK2 1 0.17 0 0
132 INT189751 Regulation of Regulation of TERT 1 0.11 0.08 0
133 INT169913 Positive_regulation of Gene_expression of Cdk2 1 0.21 0.08 0
134 INT277859 Protein_catabolism of Cdk2 1 0.43 0.23 0
135 INT294916 Negative_regulation of Negative_regulation of ACD 1 0.36 0 0
136 INT354742 Phosphorylation of ATM 1 0.50 1.74 0
137 INT333793 Transcription of Cdk2 1 0.46 0 0
138 INT331373 Positive_regulation of Transcription of Tert 1 0.24 0.17 0
139 INT260376 Protein_catabolism of TERT 1 0.02 0.36 0
140 INT341855 Positive_regulation of Positive_regulation of CDK2 1 0.06 0.51 0
141 INT186974 Negative_regulation of Transcription of Tert 1 0.27 0 0
142 INT188012 Regulation of Binding of TP53BP1 1 0.58 0.14 0
143 INT333816 Regulation of Positive_regulation of Cdk2 1 0.30 0 0
144 INT289620 Regulation of Binding of CDK2 1 0.28 0.22 0
145 INT329779 Positive_regulation of CHEK1 1 0.22 0.76 0
146 INT189772 Positive_regulation of Regulation of TEP1 1 0.06 0.08 0
147 INT286182 Positive_regulation of Gene_expression of Blm 1 0.29 0.53 0
148 INT189744 Regulation of Regulation of TEP1 1 0.03 0.08 0
149 INT186988 Negative_regulation of Gene_expression of Tert 1 0.27 1.06 0
150 INT221708 Binding of CHEK2 1 0.01 0 0
151 INT325169 Regulation of Negative_regulation of CDK2 1 0.34 0.05 0
152 INT333817 Localization of Cdk2 1 0.50 0.22 0
153 INT225187 Positive_regulation of Binding of CDK2 1 0.56 0.87 0
154 INT186986 Negative_regulation of Tert 1 0.27 0.61 0
155 INT329783 Phosphorylation of CHEK1 1 0.26 0.82 0
156 INT294913 Negative_regulation of Gene_expression of ACD 1 0.36 0.14 0
157 INT188015 Negative_regulation of Localization of TP53BP1 1 0.35 0.16 0
158 INT188011 Negative_regulation of Gene_expression of TP53BP1 1 0.40 0.78 0
159 INT310799 Negative_regulation of Gene_expression of PTGES3 1 0.17 0 0
160 INT186987 Regulation of Tert 1 0.13 0 0
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