GO:0000790

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Name nuclear chromatin
Categary Component
Go Slim No
Go Link GO:0000790
Unique Molecular Interactions 1450
Total Molecular Interactions 1969
Total Single Events 15111
Pain Genes Associated 83

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nuclear chromatin. They are ordered first by their pain relevance and then by number of times they were reported for nuclear chromatin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
3 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
4 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
5 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
6 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
7 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
8 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
9 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
10 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
11 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
12 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
13 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
14 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
15 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
16 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
17 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
18 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.92 1.62
19 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
20 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
21 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
22 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
23 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
24 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
25 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
26 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
27 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
28 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
29 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
30 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
31 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
32 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
33 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
34 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
35 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
36 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
37 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24
38 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23
39 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
40 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
41 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
42 INT298260 Binding of Runx3 and Pou4f1 1 0.52 2.08 1.22
43 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19
44 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
45 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17
46 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
47 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09
48 INT298292 Runx3 Positive_regulation of Gene_expression of Ntrk3 1 0.35 1.36 1.09
49 INT100678 IL4 Positive_regulation of STAT6 1 0.49 2.63 1.08
50 INT156462 Creb1 Regulation of Ephb1 1 0.29 0 1.07
51 INT119888 Binding of Creb1 and Usf1 1 0.18 0.15 1.05
52 INT69011 Binding of Cebpb and Nfkb1 1 0.19 0.75 1.04
53 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
54 INT95378 Binding of Jun and Jund 5 0.20 2.06 1.02
55 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
56 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
57 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1
58 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
59 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99
60 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97
61 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
62 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96
63 INT133076 STAT6 Positive_regulation of OPRM1 1 0.38 0 0.95
64 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95
65 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
66 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
67 INT117005 Sfpi1 Positive_regulation of Oprm1 1 0.52 0.56 0.94
68 INT82126 CEBPB Regulation of Gene_expression of Oprd1 1 0.00 0 0.93
69 INT141276 Negative_regulation of Il18 Negative_regulation of Gene_expression of Hand2 1 0.25 0.8 0.92
70 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
71 INT151263 Jun Positive_regulation of S100a8 1 0.00 0.95 0.92
72 INT82120 IK Positive_regulation of CEBPB 1 0.00 0 0.92
73 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
74 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
75 INT133073 IL4 Positive_regulation of Phosphorylation of STAT6 1 0.39 0 0.9
76 INT77253 Binding of gr and Creb1 1 0.03 0.4 0.9
77 INT309140 Dlat Positive_regulation of Creb1 1 0.06 1.1 0.9
78 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
79 INT183269 Binding of CEBPB and CPOX 1 0.07 1.61 0.89
80 INT142128 Nrgn Regulation of Creb1 1 0.38 0.25 0.89
81 INT73653 Binding of Creb1 and Fos 1 0.40 1.49 0.87
82 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
83 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84
84 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
85 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
86 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
87 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81
88 INT100677 IL13 Positive_regulation of STAT6 1 0.36 1.95 0.81
89 INT298279 Pou4f1 Positive_regulation of Gene_expression of Runx3 1 0.50 1.31 0.81
90 INT109142 Calca Positive_regulation of Transcription of Creb1 1 0.47 0.13 0.8
91 INT182839 Camk4 Positive_regulation of Creb1 3 0.49 1.81 0.79
92 INT245564 Runx3 Negative_regulation of Ntrk2 3 0.61 1.61 0.79
93 INT114924 Creb1 Regulation of Positive_regulation of Oprm1 1 0.09 0.13 0.79
94 INT186439 Prkaca Regulation of Phosphorylation of Creb1 1 0.06 0.08 0.79
95 INT131194 Creb1 Positive_regulation of Gene_expression of Pdyn 1 0.26 0.08 0.79
96 INT151807 Binding of NFATC1 and OPRM1 1 0.19 0 0.79
97 INT302831 Binding of Creb1 and Mapkapk5 1 0.07 1.3 0.79
98 INT172982 Binding of MUC1 and MUC4 1 0.30 2.46 0.78
99 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
100 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
101 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
102 INT261413 Positive_regulation of GRIN1 Positive_regulation of Positive_regulation of Creb1 1 0.00 0.81 0.77
103 INT199476 Il4 Positive_regulation of Transcription of Stat6 1 0.01 0.97 0.77
104 INT200097 Negative_regulation of Binding of Il1a and Jun 1 0.00 2.76 0.77
105 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76
106 INT106335 Olr1254 Positive_regulation of Phosphorylation of Creb1 1 0.03 0 0.76
107 INT90118 Jun Regulation of Gene_expression of Nfkb1 1 0.18 0.39 0.76
108 INT109141 Calca Positive_regulation of Creb1 1 0.47 0.13 0.76
109 INT151808 NFATC1 Positive_regulation of Positive_regulation of OPRM1 1 0.20 0 0.76
110 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76
111 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
112 INT200093 Binding of Il1a and Jun 1 0.00 2.64 0.76
113 INT90123 Jun Positive_regulation of Gene_expression of Fos 1 0.47 0.39 0.76
114 INT109143 Calca Positive_regulation of Phosphorylation of Creb1 1 0.47 0.13 0.76
115 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75
116 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74
117 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
118 INT186436 Phosphorylation of Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
119 INT186445 Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
120 INT186443 Phosphorylation of Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
121 INT186438 Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
122 INT186444 Creb1 Regulation of FOS 1 0.49 0.43 0.72
123 INT253828 Creb1 Positive_regulation of Gene_expression of Cartpt 1 0.19 0.15 0.72
124 INT186442 Phosphorylation of Creb1 Regulation of FOS 1 0.49 0.43 0.72
125 INT186440 Phosphorylation of Creb1 Regulation of Jun 1 0.21 0.43 0.72
126 INT123300 Mks1 Positive_regulation of Creb1 1 0.01 0.35 0.7
127 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69
128 INT287099 Binding of Bdnf and T 1 0.10 1.1 0.69
129 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68
130 INT8980 Gal Regulation of PLCB1 1 0.18 0.13 0.68
131 INT199489 Stat6 Positive_regulation of Oprm1 1 0.02 0.85 0.68
132 INT124257 Plat Positive_regulation of Jun 5 0.12 3.33 0.67
133 INT184120 Il4 Positive_regulation of Stat6 3 0.09 2.39 0.67
134 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
135 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
136 INT111555 Negative_regulation of Npr1 Negative_regulation of Positive_regulation of Creb1 1 0.02 0.58 0.66
137 INT114947 YY1 Positive_regulation of Gene_expression of RXRA 1 0.33 0.25 0.65
138 INT266064 Binding of PAG1 and Creb1 1 0.04 1.52 0.65
139 INT266049 Binding of Ceacam3 and Creb1 1 0.14 1.53 0.65
140 INT132154 PSG7 Positive_regulation of Localization of MUC1 1 0.00 0 0.65
141 INT235881 Prkaca Positive_regulation of Creb1 2 0.10 0.16 0.64
142 INT135361 Prr14 Positive_regulation of Mecp2 1 0.24 0.15 0.64
143 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
144 INT135363 Mecp2 Positive_regulation of Mbd1 1 0.50 0.15 0.64
145 INT298262 Pou4f1 Positive_regulation of Positive_regulation of Ntrk3 1 0.36 0.79 0.63
146 INT117007 Binding of Oprm1 and Sfpi1 1 0.50 0.07 0.63
147 INT114948 NCOA1 Positive_regulation of Positive_regulation of PPARA 1 0.20 0.24 0.62
148 INT266047 Creb1 Regulation of Ceacam3 1 0.20 1.15 0.62
149 INT186429 Camk2a Regulation of Regulation of Creb1 1 0.09 0.09 0.62
150 INT121873 Creb1 Regulation of Phosphorylation of Car2 1 0.10 0 0.62
151 INT128869 Gabrg1 Positive_regulation of Transcription of Jun 1 0.09 0.55 0.62
152 INT54487 Rabep2 Regulation of Gene_expression of Jun 1 0.06 0 0.61
153 INT114949 NCOA1 Positive_regulation of Gene_expression of RXRA 1 0.13 0.24 0.61
154 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
155 INT123301 Car2 Positive_regulation of Creb1 1 0.21 0.28 0.61
156 INT98725 Msr1 Positive_regulation of Gene_expression of Creb1 1 0.00 0.09 0.6
157 INT56700 Penk Regulation of FER 1 0.00 0 0.59
158 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58
159 INT73654 Binding of Jun and Pim3 1 0.02 0.99 0.58
160 INT186434 Trib3 Positive_regulation of Phosphorylation of Creb1 1 0.05 0.26 0.58
161 INT149480 CEBPD Positive_regulation of CEBPB 1 0.50 0.15 0.58
162 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57
163 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
164 INT317637 Ngf Regulation of Creb1 1 0.10 0.11 0.57
165 INT100681 Negative_regulation of IL13 Positive_regulation of STAT6 1 0.30 1.39 0.57
166 INT90115 Ntrk2 Regulation of Jun 1 0.01 0.27 0.57
167 INT92974 Creb1 Regulation of Positive_regulation of Galr1 1 0.32 0 0.57
168 INT305744 Fst Positive_regulation of Creb1 1 0.12 0.33 0.57
169 INT305732 Tst Positive_regulation of Creb1 1 0.12 0.33 0.57
170 INT73656 Creb1 Positive_regulation of Transcription of Pdyn 1 0.42 0.97 0.56
171 INT296169 Binding of Htr4 and Creb1 1 0.49 0.1 0.56
172 INT296293 Prkaca Regulation of Positive_regulation of Creb1 1 0.16 0.62 0.55
173 INT105424 Creb1 Positive_regulation of Gene_expression of Penk 1 0.49 0 0.55
174 INT114928 Positive_regulation of Creb1 Positive_regulation of Positive_regulation of Oprm1 1 0.16 0.05 0.54
175 INT245558 Runx3 Regulation of Ngfr 1 0.06 1 0.53
176 INT271902 Binding of KCNK1 and Jun 1 0.12 0.08 0.53
177 INT305738 Binding of Creb1 and Atf6b 1 0.08 0.34 0.53
178 INT247265 Mecp2 Regulation of Fos 1 0.25 0.38 0.52
179 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
180 INT143861 Nfatc1 Regulation of Gene_expression of NUP214 1 0.00 0.61 0.52
181 INT143859 Bdnf Positive_regulation of Gene_expression of Nfatc1 1 0.00 0.61 0.52
182 INT335291 SLC15A4 Negative_regulation of NFATC1 1 0.01 0.45 0.51
183 INT135360 Binding of Mecp2 and Aadac 1 0.03 0.19 0.51
184 INT117006 Sfpi1 Negative_regulation of Oprm1 1 0.39 0.29 0.49
185 INT219038 Creb1 Regulation of Gene_expression of Bdnf 1 0.25 0.25 0.49
186 INT184117 Il12a Positive_regulation of Stat6 1 0.07 0.28 0.48
187 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48
188 INT305735 Binding of Bdnf and Creb1 1 0.08 0.49 0.47
189 INT305746 Positive_regulation of Creb1 Positive_regulation of BDNF 1 0.32 0.41 0.47
190 INT305743 Binding of Bdnf and Positive_regulation of Positive_regulation of Creb1 1 0.11 0.49 0.47
191 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
192 INT235882 Creb1 Positive_regulation of Positive_regulation of Bdnf 1 0.11 0.17 0.47
193 INT338426 Binding of Hand1 and Hand2 2 0.06 2 0.46
194 INT305736 Positive_regulation of Creb1 Positive_regulation of Bdnf 1 0.10 0.41 0.46
195 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
196 INT317640 Slc3a1 Positive_regulation of Creb1 1 0.12 0.58 0.46
197 INT275549 Il10 Positive_regulation of Localization of Hand2 1 0.01 1.3 0.46
198 INT275550 Hand1 Positive_regulation of Localization of Hand2 1 0.00 1.29 0.46
199 INT161162 Creb1 Regulation of Nts 1 0.19 0.15 0.45
200 INT349853 Binding of Hspb1 and Jun 1 0.14 2.3 0.45

Single Events

The table below shows the top 100 pain related interactions that have been reported for nuclear chromatin. They are ordered first by their pain relevance and then by number of times they were reported in nuclear chromatin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
2 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
3 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
4 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
5 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26
6 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
7 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77
8 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39
9 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
10 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
11 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
12 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66
13 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
14 INT16714 Regulation of Creb1 64 0.62 22.23 33.56
15 INT47764 Binding of Jun 106 0.48 22.62 31.39
16 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25
17 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
18 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04
19 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
20 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
21 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19
22 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28
23 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17
24 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46
25 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
26 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
27 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52
28 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
29 INT62577 Negative_regulation of Creb1 55 0.59 19.68 18.1
30 INT61158 Negative_regulation of Creb1 33 0.59 11.54 18.06
31 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
32 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
33 INT102023 Regulation of Creb1 51 0.62 16.29 16.71
34 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
35 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
36 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
37 INT17593 Regulation of Jun 37 0.60 5.5 14.35
38 INT173505 Localization of Hand2 63 0.57 45.32 13.66
39 INT107248 Negative_regulation of Gene_expression of Creb1 26 0.58 9.24 13.41
40 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37
41 INT16713 Binding of Creb1 53 0.48 20.24 13.06
42 INT203490 Gene_expression of Runx3 19 0.76 27.56 12.57
43 INT114274 Gene_expression of Rxra 67 0.70 36.77 12.5
44 INT15756 Positive_regulation of Gene_expression of Jun 29 0.69 16.58 12.06
45 INT203473 Gene_expression of Pou4f1 69 0.76 25.94 11.36
46 INT52233 Transcription of Jun 37 0.66 6.39 11.15
47 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08
48 INT62576 Transcription of Creb1 34 0.69 16.97 10.6
49 INT109280 Negative_regulation of Phosphorylation of Creb1 29 0.59 11.81 10.37
50 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
51 INT29988 Gene_expression of Mecp2 27 0.78 5.45 9.47
52 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28
53 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24
54 INT109279 Regulation of Phosphorylation of Creb1 14 0.62 4.06 8.96
55 INT35366 Binding of AR 87 0.47 30.52 8.9
56 INT49802 Localization of MUC1 75 0.81 44.74 8.87
57 INT61264 Regulation of Jun 36 0.61 18.42 8.71
58 INT64815 Binding of Jun 49 0.48 21.47 8.59
59 INT93673 Transcription of Creb1 19 0.66 9.27 8.26
60 INT53975 Positive_regulation of Binding of Jun 28 0.70 4.67 8.16
61 INT64816 Transcription of Jun 31 0.69 16.01 7.64
62 INT9476 Regulation of Gene_expression of Jun 14 0.43 4.25 7.61
63 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
64 INT10344 Localization of Jun 23 0.73 6.36 7.46
65 INT116619 Positive_regulation of Positive_regulation of Creb1 25 0.69 8.32 7.3
66 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
67 INT106330 Regulation of Positive_regulation of Creb1 11 0.56 5.57 7.06
68 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01
69 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
70 INT53491 Negative_regulation of Jun 28 0.57 14.2 6.9
71 INT47817 Positive_regulation of Positive_regulation of Jun 21 0.66 3.7 6.83
72 INT114642 Negative_regulation of Positive_regulation of Creb1 12 0.57 2.32 6.75
73 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61
74 INT47765 Negative_regulation of Binding of Jun 21 0.43 5.05 6.38
75 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
76 INT92971 Binding of Creb1 31 0.47 11.3 6.22
77 INT144539 Phosphorylation of Mecp2 3 0.82 6.18 6.2
78 INT135359 Positive_regulation of Mecp2 4 0.70 4.35 6.05
79 INT105215 Negative_regulation of Pou4f1 16 0.53 9.42 5.97
80 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
81 INT73649 Phosphorylation of Jun 28 0.80 11.01 5.87
82 INT61986 Localization of Creb1 16 0.69 2.12 5.66
83 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
84 INT117004 Gene_expression of Sfpi1 21 0.75 15.95 5.29
85 INT60585 Regulation of TP53 59 0.59 54.55 5.21
86 INT93484 Negative_regulation of Positive_regulation of Jun 30 0.58 9.31 5.18
87 INT102019 Regulation of Gene_expression of Creb1 14 0.61 5.27 5.08
88 INT99091 Regulation of AR 70 0.45 31.68 5.05
89 INT102202 Negative_regulation of Positive_regulation of Creb1 11 0.58 4.55 4.99
90 INT181186 Binding of Rxra 78 0.35 14.93 4.87
91 INT203506 Positive_regulation of Pou4f1 3 0.49 6.17 4.85
92 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78
93 INT204449 Gene_expression of T 17 0.32 9.77 4.77
94 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
95 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
96 INT346257 Binding of RUNX2 1 0.44 9.05 4.64
97 INT5205 Localization of AR 43 0.80 12.87 4.63
98 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63
99 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
100 INT49805 Positive_regulation of MUC1 56 0.70 44.5 4.56
101 INT121866 Localization of Creb1 13 0.73 1.95 4.48
102 INT94466 Regulation of Gene_expression of Hand2 14 0.28 7.97 4.46
103 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
104 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28
105 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
106 INT90890 Positive_regulation of RARA 25 0.67 9.32 4.2
107 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
108 INT64163 Negative_regulation of Gene_expression of Jun 13 0.58 3.86 4.03
109 INT156131 Binding of Hand2 14 0.25 10.35 3.99
110 INT6661 Positive_regulation of Positive_regulation of Jun 31 0.50 7.12 3.89
111 INT105217 Regulation of Pou4f1 8 0.60 6.15 3.88
112 INT64817 Positive_regulation of Binding of Jun 16 0.69 6.78 3.81
113 INT84809 Positive_regulation of Gene_expression of MUC1 39 0.70 36.42 3.75
114 INT111532 Gene_expression of Nfatc1 15 0.75 5.27 3.73
115 INT15776 Localization of Jun 10 0.74 3.9 3.69
116 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
117 INT318967 Gene_expression of Mecp2 9 0.77 11.52 3.55
118 INT346244 Positive_regulation of RUNX2 1 0.63 7.42 3.54
119 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53
120 INT61570 Positive_regulation of Transcription of Jun 10 0.35 1.62 3.45
121 INT70387 Negative_regulation of Positive_regulation of Jun 14 0.37 3.76 3.23
122 INT24873 Binding of KLF1 12 0.07 6.73 3.1
123 INT8103 Binding of TP53 46 0.44 40.2 2.96
124 INT163080 Gene_expression of STAT6 5 0.59 3.18 2.94
125 INT130080 Negative_regulation of Rxra 6 0.53 2.08 2.92
126 INT133080 Gene_expression of GATA3 15 0.61 5.64 2.89
127 INT111554 Positive_regulation of Regulation of Creb1 4 0.50 2.12 2.85
128 INT31450 Binding of HIST1H1B 20 0.37 10.21 2.84
129 INT156021 Positive_regulation of Transcription of Creb1 8 0.57 3.36 2.83
130 INT64819 Positive_regulation of Transcription of Jun 6 0.50 4.41 2.79
131 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
132 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
133 INT69007 Binding of Cebpb 10 0.48 2.21 2.6
134 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
135 INT194495 Regulation of Transcription of Jun 4 0.26 2.85 2.6
136 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55
137 INT111528 Positive_regulation of Gene_expression of Nfatc1 5 0.67 3.24 2.52
138 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
139 INT185927 Positive_regulation of Positive_regulation of AR 12 0.34 6.35 2.5
140 INT203441 Positive_regulation of Gene_expression of Runx3 4 0.66 4.35 2.49
141 INT194748 Positive_regulation of Nfatc1 16 0.64 5.07 2.44
142 INT158666 Regulation of Transcription of Creb1 6 0.45 2.41 2.44
143 INT9473 Binding of MUC1 66 0.48 46.77 2.36
144 INT55952 Transcription of TP53 16 0.61 12.14 2.36
145 INT59818 Negative_regulation of PLCB1 7 0.57 2.24 2.28
146 INT163082 Negative_regulation of STAT6 2 0.42 2.35 2.28
147 INT173005 Transcription of MUC1 11 0.63 10.15 2.24
148 INT87168 Positive_regulation of Binding of Creb1 4 0.48 4.6 2.21
149 INT217447 Positive_regulation of Positive_regulation of Nfatc1 4 0.46 3.34 2.2
150 INT159118 Protein_catabolism of Creb1 3 0.61 0.37 2.17
151 INT106718 Regulation of Positive_regulation of Creb1 9 0.45 3.7 2.16
152 INT169318 Positive_regulation of Rxra 15 0.42 4.35 2.12
153 INT53981 Regulation of Binding of Jun 5 0.44 0.63 2.12
154 INT59358 Regulation of Gene_expression of Jun 10 0.61 3.7 2.11
155 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
156 INT53434 Positive_regulation of T 7 0.07 3.67 2.09
157 INT49803 Negative_regulation of MUC1 37 0.58 26.37 2.06
158 INT220211 Gene_expression of RUNX2 7 0.71 7.31 2
159 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
160 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
161 INT130082 Regulation of Rxra 6 0.42 3.78 1.96
162 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
163 INT129239 Positive_regulation of Positive_regulation of Hand2 5 0.43 2.81 1.93
164 INT129240 Positive_regulation of Stat6 6 0.67 1.96 1.92
165 INT144541 Negative_regulation of Gene_expression of Mecp2 3 0.42 1.43 1.9
166 INT65855 Localization of TP53 18 0.76 17.08 1.89
167 INT53982 Regulation of Positive_regulation of Jun 4 0.54 0.9 1.89
168 INT199724 Positive_regulation of Gene_expression of Rxra 11 0.45 6.22 1.88
169 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
170 INT230954 Negative_regulation of RUNX2 3 0.39 4.54 1.79
171 INT247261 Negative_regulation of Mecp2 1 0.42 1.71 1.78
172 INT111534 Regulation of Nfatc1 11 0.29 2.11 1.77
173 INT144538 Regulation of Phosphorylation of Mecp2 2 0.45 1.87 1.77
174 INT117003 Binding of Sfpi1 5 0.47 5.04 1.74
175 INT135355 Binding of Mecp2 4 0.37 0.83 1.72
176 INT100692 Phosphorylation of STAT6 5 0.78 3.42 1.7
177 INT84722 Regulation of Gene_expression of AR 20 0.61 7.73 1.69
178 INT192092 Positive_regulation of Gene_expression of Rara 8 0.32 4.41 1.68
179 INT116022 Positive_regulation of Positive_regulation of RARA 3 0.11 0.94 1.68
180 INT346250 Positive_regulation of Binding of RUNX2 1 0.63 3.19 1.63
181 INT186286 Phosphorylation of Stat6 18 0.79 5.07 1.61
182 INT10598 Gene_expression of Ar 10 0.64 3.44 1.61
183 INT15969 Negative_regulation of Ar 11 0.43 2.77 1.59
184 INT231917 Gene_expression of Cebpb 10 0.25 4.45 1.56
185 INT132163 Positive_regulation of Localization of MUC1 9 0.19 8.96 1.54
186 INT82122 Positive_regulation of CEBPB 3 0.67 0.51 1.54
187 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
188 INT245537 Negative_regulation of Runx3 4 0.56 4 1.53
189 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
190 INT144542 Positive_regulation of Phosphorylation of Mecp2 2 0.68 1.43 1.5
191 INT318963 Positive_regulation of Mecp2 5 0.50 1.78 1.49
192 INT272884 Gene_expression of Hdac2 19 0.43 14.55 1.48
193 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
194 INT128865 Regulation of Positive_regulation of RXRA 1 0.08 0.64 1.48
195 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
196 INT89858 Positive_regulation of STAT6 10 0.66 7.81 1.47
197 INT100672 Transcription of Hand2 9 0.42 2.84 1.47
198 INT128863 Positive_regulation of RXRA 1 0.12 0.63 1.47
199 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
200 INT67457 Binding of Rara 12 0.24 8.28 1.45
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