GO:0000795

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Name synaptonemal complex
Categary Component
Go Slim No
Go Link GO:0000795
Unique Molecular Interactions 42
Total Molecular Interactions 53
Total Single Events 449
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for synaptonemal complex. They are ordered first by their pain relevance and then by number of times they were reported for synaptonemal complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT60047 Oprl1 Negative_regulation of Phosphorylation of Syn1 1 0.05 0.17 1.05
2 INT303063 Akt1 Negative_regulation of Gene_expression of Syn1 1 0.09 0.45 0.31
3 INT35021 Ptz1b Regulation of Phosphorylation of Syn1 1 0.01 0 0.26
4 INT35023 Ptz1b Positive_regulation of Phosphorylation of Syn1 1 0.01 0 0.22
5 INT45371 IGF1 Regulation of Smc1b 1 0.08 0 0.14
6 INT182607 Binding of MLH1 and MSH3 1 0.04 0.81 0.11
7 INT303081 Binding of Mafk and Syn1 1 0.07 0.37 0.1
8 INT43121 Apoa2 Regulation of Smc1b 1 0.02 0 0.08
9 INT261395 Nsdhl Positive_regulation of Syn1 1 0.00 0.59 0.07
10 INT261392 Binding of Nsdhl and Syn1 1 0.00 0.65 0.07
11 INT303061 Akt1 Negative_regulation of Syn1 1 0.06 0 0.07
12 INT303057 Binding of Syn1 and Syt1 1 0.07 0.19 0.05
13 INT303060 Akt1 Regulation of Gene_expression of Syn1 1 0.04 0 0.05
14 INT333841 Binding of Rad51 and Mir17 1 0.02 0.52 0.05
15 INT303064 Negative_regulation of Akt1 Positive_regulation of Gene_expression of Syn1 1 0.07 0.25 0.04
16 INT290556 Binding of MLH1 and MSH2 3 0.34 2.74 0
17 INT190061 Binding of MLH1 and Mlh1 1 0.01 0.92 0
18 INT300616 Binding of MLH1 and PMS2 1 0.36 0.53 0
19 INT235697 Binding of Clcn1 and Syn1 1 0.00 0.48 0
20 INT277136 Ebp Positive_regulation of Gene_expression of Mlh1 1 0.01 1.45 0
21 INT190049 Binding of Mlh1 and Msh3 1 0.24 0.22 0
22 INT190048 Binding of Mlh1 and Msh2 1 0.31 0.22 0
23 INT276759 ABCB1 Regulation of TOP2A 1 0.04 0.61 0
24 INT190062 Binding of MLH1 and Msh2 1 0.01 0.91 0
25 INT300617 Binding of MSH6 and MLH1 1 0.28 0.53 0
26 INT305543 Binding of Top2a and Trp53 1 0.37 0.91 0
27 INT217315 Binding of UBE2I and ERVW-1 1 0.01 1.56 0
28 INT279888 Binding of Rec8 and Nipbl 1 0.01 0.81 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for synaptonemal complex. They are ordered first by their pain relevance and then by number of times they were reported in synaptonemal complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT60044 Gene_expression of Syn1 38 0.78 4.98 14.61
2 INT60046 Positive_regulation of Syn1 16 0.70 2 13.9
3 INT63728 Transcription of Syn1 6 0.72 0.38 6.07
4 INT63726 Positive_regulation of Transcription of Syn1 1 0.70 0.39 5.99
5 INT35019 Phosphorylation of Syn1 11 0.82 0.33 4.28
6 INT63727 Positive_regulation of Gene_expression of Syn1 4 0.50 2.1 3.31
7 INT35017 Negative_regulation of Phosphorylation of Syn1 5 0.59 0.24 3.22
8 INT61311 Negative_regulation of Gene_expression of Syn1 4 0.59 0.48 2.85
9 INT115674 Negative_regulation of Syn1 3 0.41 1.22 1.81
10 INT24238 Phosphorylation of Syn1 11 0.45 2.97 1.65
11 INT107985 Gene_expression of MLH1 29 0.67 31.31 1.46
12 INT60043 Regulation of Syn1 2 0.27 0.33 1.33
13 INT71926 Gene_expression of Smc1b 6 0.35 3.64 1.27
14 INT63729 Regulation of Gene_expression of Syn1 2 0.62 0.43 1.14
15 INT86908 Negative_regulation of MLH1 7 0.43 6.98 1.12
16 INT19849 Positive_regulation of Smc1b 8 0.50 4.09 1.01
17 INT92139 Binding of MLH1 12 0.42 15.62 1
18 INT19848 Regulation of Smc1b 4 0.61 2.06 0.71
19 INT35018 Regulation of Phosphorylation of Syn1 1 0.44 0 0.52
20 INT231296 Gene_expression of Syn1 8 0.23 0.65 0.49
21 INT71928 Positive_regulation of Gene_expression of Smc1b 5 0.14 1.65 0.43
22 INT217300 Regulation of Syn1 3 0.11 1.64 0.3
23 INT316935 Localization of Syn1 2 0.26 0 0.26
24 INT166557 Binding of Smc1b 1 0.15 0.27 0.22
25 INT157289 Positive_regulation of Phosphorylation of Syn1 2 0.28 0.74 0.2
26 INT24237 Binding of Syn1 2 0.05 0.18 0.17
27 INT303071 Binding of Syn1 1 0.11 0.36 0.17
28 INT184997 Gene_expression of TOP2A 6 0.63 1.65 0.15
29 INT157286 Positive_regulation of Syn1 1 0.26 0.41 0.15
30 INT157284 Positive_regulation of Positive_regulation of Syn1 1 0.26 0.41 0.15
31 INT236392 Regulation of Rad51 1 0.00 0.3 0.14
32 INT182621 Localization of MLH1 9 0.64 9.31 0.12
33 INT181744 Negative_regulation of Gene_expression of MLH1 3 0.05 7.67 0.12
34 INT147244 Regulation of MLH1 3 0.08 2.64 0.12
35 INT188311 Negative_regulation of Regulation of Smc1b 1 0.12 0.56 0.1
36 INT34927 Negative_regulation of Smc1b 2 0.25 0.49 0.09
37 INT268846 Negative_regulation of Top2a 6 0.29 3.06 0.07
38 INT261349 Negative_regulation of Syn1 1 0.01 0.72 0.06
39 INT258473 Binding of TOP2A 3 0.05 1.65 0.05
40 INT333807 Localization of Rad51 1 0.24 0.52 0.05
41 INT251220 Regulation of Phosphorylation of Syn1 1 0.09 0 0.05
42 INT307479 Positive_regulation of Phosphorylation of Syn1 1 0.11 0 0.05
43 INT217303 Regulation of Regulation of Syn1 1 0.05 0.99 0.04
44 INT190022 Positive_regulation of Mlh1 2 0.38 3.16 0.03
45 INT303077 Protein_catabolism of Syn1 1 0.07 0 0.03
46 INT235686 Gene_expression of Top2a 5 0.60 4.34 0
47 INT118827 Regulation of TOP2A 4 0.04 1.75 0
48 INT36301 Negative_regulation of TOP2A 3 0.57 2.66 0
49 INT190039 Gene_expression of Mlh1 3 0.68 6.14 0
50 INT190038 Binding of Mlh1 2 0.28 3.11 0
51 INT268847 Binding of Top2a 2 0.24 0.6 0
52 INT217331 Binding of UBE2I 1 0.12 2.88 0
53 INT211582 Transcription of Mlh1 1 0.41 0.34 0
54 INT188308 Negative_regulation of Gene_expression of Smc1b 1 0.12 0.07 0
55 INT268375 Positive_regulation of Positive_regulation of MLH1 1 0.12 0.76 0
56 INT190012 Regulation of Mlh1 1 0.34 0.34 0
57 INT296158 Negative_regulation of Rad51 1 0.17 0.11 0
58 INT308260 Positive_regulation of TOP2A 1 0.03 0.58 0
59 INT256916 Regulation of Gene_expression of Top2a 1 0.47 1.2 0
60 INT190058 Positive_regulation of Localization of MLH1 1 0.02 0.84 0
61 INT185286 Transcription of MLH1 1 0.06 1.12 0
62 INT350584 Negative_regulation of Gene_expression of Mlh1 1 0.51 2.21 0
63 INT279867 Binding of Rec8 1 0.01 0.81 0
64 INT268369 Positive_regulation of Negative_regulation of MLH1 1 0.11 0.76 0
65 INT107990 Positive_regulation of Gene_expression of MLH1 1 0.15 0 0
66 INT239664 Positive_regulation of Gene_expression of TOP2A 1 0.01 0.1 0
67 INT256921 Regulation of Top2a 1 0.21 1.28 0
68 INT34928 Localization of Smc1b 1 0.44 0 0
69 INT268845 Positive_regulation of Binding of Top2a 1 0.05 0.33 0
70 INT211583 Regulation of Transcription of Mlh1 1 0.27 0.34 0
71 INT273508 Negative_regulation of Gene_expression of Top2a 1 0.21 0.17 0
72 INT268359 Positive_regulation of MLH1 1 0.12 0.76 0
73 INT296159 Gene_expression of Rad51 1 0.11 0.11 0
74 INT175425 Negative_regulation of Negative_regulation of MLH1 1 0.19 0.73 0
75 INT279838 Protein_catabolism of Rec8 1 0.02 0.81 0
76 INT217337 Gene_expression of UBE2I 1 0.26 1.32 0
77 INT350588 Negative_regulation of Mlh1 1 0.38 3.05 0
78 INT217348 Positive_regulation of Gene_expression of UBE2I 1 0.23 1.32 0
79 INT303683 Regulation of Positive_regulation of Smc1b 1 0.05 0 0
80 INT279842 Regulation of Rec8 1 0.01 0.6 0
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