GO:0000932

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Name cytoplasmic mRNA processing body
Categary Component
Go Slim No
Go Link GO:0000932
Unique Molecular Interactions 77
Total Molecular Interactions 111
Total Single Events 353
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cytoplasmic mRNA processing body. They are ordered first by their pain relevance and then by number of times they were reported for cytoplasmic mRNA processing body. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
2 INT341218 Binding of Eif4e and Eif4ebp1 1 0.19 2.65 1.23
3 INT315185 Binding of CNOT1 and Tg(CAG-EGFP)D4Nagy 1 0.04 0.16 0.74
4 INT142994 Binding of UPF1 and FCMTE1 1 0.00 0.91 0.7
5 INT309123 Edc4 Positive_regulation of Car1 1 0.02 0.51 0.66
6 INT224853 Binding of Bdnf and Eif4e 1 0.10 0 0.5
7 INT150205 Tnrc6a Negative_regulation of PTGS2 1 0.00 0.42 0.49
8 INT309126 Edc4 Positive_regulation of Akt1 1 0.02 0.99 0.47
9 INT309127 Edc4 Positive_regulation of Bdnf 1 0.04 0.37 0.47
10 INT309135 Edc4 Regulation of Positive_regulation of Rorb 1 0.00 0.54 0.47
11 INT142826 UPF1 Positive_regulation of CREB1 1 0.11 0 0.46
12 INT309113 Edc4 Positive_regulation of Gene_expression of Creb1 1 0.03 0.45 0.43
13 INT309145 Positive_regulation of Edc4 Positive_regulation of Creb1 1 0.02 0.35 0.42
14 INT309114 Tecr Negative_regulation of Edc4 1 0.00 0.77 0.4
15 INT309115 Edc4 Positive_regulation of Gene_expression of Bdnf 1 0.04 0.77 0.39
16 INT309120 Edc4 Negative_regulation of Positive_regulation of Mapk8 1 0.01 1.03 0.36
17 INT175552 Binding of CASR and UPF1 1 0.01 0.89 0.33
18 INT309132 Edc4 Negative_regulation of Positive_regulation of Trib3 1 0.00 0.69 0.33
19 INT341215 Binding of Eif4e and Eif4g3 1 0.10 0.41 0.33
20 INT309128 Edc4 Positive_regulation of Positive_regulation of Ephb1 1 0.01 0.58 0.33
21 INT309119 Edc4 Positive_regulation of Regulation of Bdnf 1 0.04 0.58 0.29
22 INT309122 Edc4 Positive_regulation of Phosphorylation of Mapk8 1 0.02 0.73 0.28
23 INT309134 Edc4 Positive_regulation of Ephb1 1 0.01 0.54 0.27
24 INT309160 Binding of Esr1 and Edc4 1 0.03 0.34 0.24
25 INT309116 Edc4 Negative_regulation of Mapk8 1 0.01 0.43 0.22
26 INT324815 Binding of Hmgb1 and Caprin1 1 0.01 0.65 0.19
27 INT350702 Rc3h1 Positive_regulation of Protein_catabolism of Icos 1 0.35 1.56 0.18
28 INT97889 Binding of RQCD1 and NPS 1 0.13 1.69 0.17
29 INT309147 Edc4 Regulation of Gsdmc 1 0.00 0.38 0.15
30 INT346411 Binding of Caprin1 and Mtus1 1 0.00 0.17 0.14
31 INT303128 Tnrc6a Regulation of Gene_expression of Nos2 1 0.00 0.57 0.14
32 INT273901 Mtor Positive_regulation of Eif4e 1 0.50 0.54 0.14
33 INT346410 Binding of Caprin1 and Tesc 1 0.00 0.17 0.14
34 INT309139 Edc4 Positive_regulation of Bcl2 1 0.03 0.12 0.13
35 INT309130 Edc4 Regulation of Creb1 1 0.02 0.12 0.13
36 INT309142 Edc4 Regulation of Bcl2 1 0.02 0.12 0.13
37 INT341239 Binding of EIF4E and Eif4e 1 0.08 0.23 0.12
38 INT341238 Binding of EIF4E and Eif4g3 1 0.03 0.23 0.12
39 INT118587 Binding of UPF1 and CLEC4F 1 0.00 0.22 0.1
40 INT350694 Uts2r Negative_regulation of Negative_regulation of Rc3h1 1 0.05 0.79 0.1
41 INT309112 Edc4 Regulation of Positive_regulation of Ephb1 1 0.01 0.15 0.07
42 INT341220 Eif4e Positive_regulation of Eif4ebp1 1 0.20 0.42 0.06
43 INT257879 Negative_regulation of Eif4e Positive_regulation of Cdkn1b 1 0.28 0.54 0.06
44 INT257867 Negative_regulation of Eif4e Positive_regulation of Rb1 1 0.05 0.54 0.06
45 INT309131 Edc4 Positive_regulation of Phosphorylation of Rorb 1 0.00 0 0.04
46 INT309137 Edc4 Positive_regulation of Phosphorylation of Creb1 1 0.03 0 0.04
47 INT293899 UPF1 Positive_regulation of Gene_expression of APOB 1 0.01 0 0.04
48 INT315678 Binding of MPZ and UPF1 1 0.00 2.05 0.04
49 INT341225 Negative_regulation of Binding of Eif4e and Eif4ebp1 1 0.17 0.14 0.03
50 INT222259 EIF4E Regulation of Negative_regulation of NOD2 1 0.13 0.1 0
51 INT351466 NMD3 Positive_regulation of Protein_catabolism of UPF1 1 0.00 0.54 0
52 INT245701 CNOT1 Positive_regulation of H2-Q9 1 0.01 0.31 0
53 INT341232 Binding of EIF4A2 and Eif4e 1 0.06 0 0
54 INT315057 Binding of TOP1 and PAR4 1 0.16 1.23 0
55 INT341240 Binding of EIF4E and Eif4ebp1 1 0.04 0.5 0
56 INT307284 DCP2 Positive_regulation of HAL 1 0.00 0 0
57 INT269275 Binding of CNOT1 and Mecr 1 0.36 0.06 0
58 INT341221 Eif4e Regulation of Binding of Eif4ebp1 1 0.18 0 0
59 INT217777 EIF4E Regulation of Gene_expression of MAP3K3 1 0.05 0.19 0
60 INT297852 Nanos2 Positive_regulation of Positive_regulation of Gopc 1 0.07 0.1 0
61 INT341234 Eif4g3 Positive_regulation of Binding of EIF4E 1 0.04 0 0
62 INT263588 SPIC Positive_regulation of TRIM21 1 0.00 0.28 0
63 INT341216 Regulation of Binding of Eif4e and Eif4ebp1 1 0.11 0 0
64 INT297851 Nanos2 Regulation of Stra8 1 0.35 0.6 0
65 INT217790 EIF4E Regulation of Gene_expression of RASGRP1 1 0.01 0.19 0
66 INT297853 Nanos2 Positive_regulation of Positive_regulation of Snord116 1 0.49 0.1 0
67 INT352841 Binding of Miox and Lin28a 1 0.00 0 0
68 INT293811 Negative_regulation of EIF4E Negative_regulation of Gene_expression of CCND3 1 0.02 0.32 0
69 INT341230 Eif4g3 Positive_regulation of EIF4E 1 0.04 0 0
70 INT297846 Nanos2 Regulation of Dnmt3l 1 0.34 0.6 0
71 INT341233 Positive_regulation of Binding of EIF4E and Eif4ebp1 1 0.06 0.5 0
72 INT352842 Binding of Lin28a and Mirlet7a-1 1 0.03 0 0
73 INT341224 Eif4g3 Positive_regulation of Eif4e 1 0.14 0 0
74 INT307286 Binding of PMP2 and DCP2 1 0.04 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cytoplasmic mRNA processing body. They are ordered first by their pain relevance and then by number of times they were reported in cytoplasmic mRNA processing body. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73223 Gene_expression of UPF1 78 0.41 31.44 9.94
2 INT200963 Regulation of UPF1 10 0.01 2.18 2.67
3 INT120650 Negative_regulation of UPF1 14 0.02 6.86 2.14
4 INT148702 Positive_regulation of UPF1 29 0.31 12.9 1.91
5 INT139402 Negative_regulation of Tnrc6a 1 0.00 2.22 1.8
6 INT136788 Regulation of Eif4e 3 0.61 0 1.61
7 INT200979 Regulation of Gene_expression of UPF1 4 0.28 2.19 1.31
8 INT200972 Positive_regulation of Gene_expression of UPF1 6 0.31 1.51 1.23
9 INT103164 Binding of UPF1 4 0.29 4.15 1.22
10 INT136783 Regulation of Regulation of Eif4e 1 0.45 0 1.16
11 INT136785 Phosphorylation of Eif4e 2 0.82 0 1.1
12 INT126102 Binding of Tnrc6a 1 0.00 1.03 0.96
13 INT99206 Gene_expression of Edc4 2 0.08 1.41 0.93
14 INT309096 Positive_regulation of Edc4 1 0.09 1.97 0.93
15 INT341195 Binding of Eif4e 1 0.38 3.87 0.92
16 INT241404 Gene_expression of Caprin1 3 0.18 1.38 0.77
17 INT50855 Gene_expression of TRIM21 4 0.65 3.07 0.71
18 INT200961 Transcription of UPF1 2 0.01 0.52 0.67
19 INT200949 Negative_regulation of Gene_expression of UPF1 1 0.01 0.81 0.64
20 INT89100 Gene_expression of CNOT1 7 0.65 1.76 0.59
21 INT309103 Localization of Edc4 1 0.09 0.99 0.57
22 INT136780 Positive_regulation of Eif4e 1 0.50 0 0.55
23 INT309101 Positive_regulation of Positive_regulation of Edc4 1 0.06 1.01 0.44
24 INT200975 Positive_regulation of Transcription of UPF1 1 0.01 0.22 0.42
25 INT309104 Regulation of Edc4 1 0.03 0.55 0.41
26 INT309109 Positive_regulation of Gene_expression of Edc4 1 0.05 0.77 0.39
27 INT99205 Transcription of Edc4 1 0.02 0.07 0.26
28 INT240203 Regulation of Transcription of UPF1 1 0.01 0.3 0.26
29 INT341182 Regulation of Eif4e 1 0.35 0.75 0.25
30 INT316448 Positive_regulation of Lin28a 1 0.26 0.53 0.24
31 INT120649 Localization of UPF1 3 0.03 0.93 0.22
32 INT341163 Positive_regulation of Eif4e 1 0.54 0.56 0.19
33 INT324778 Binding of Caprin1 1 0.01 0.65 0.19
34 INT211839 Binding of EIF4E 8 0.36 0.79 0.18
35 INT178797 Regulation of Caprin1 1 0.02 0.87 0.17
36 INT178801 Phosphorylation of Caprin1 1 0.05 0.87 0.16
37 INT257859 Negative_regulation of Eif4e 1 0.23 1.07 0.16
38 INT134909 Positive_regulation of TRIM21 1 0.67 0.95 0.16
39 INT309092 Positive_regulation of Localization of Edc4 1 0.05 0.1 0.15
40 INT303120 Regulation of Tnrc6a 1 0.00 0.28 0.14
41 INT118190 Positive_regulation of CNOT1 1 0.00 0 0.14
42 INT194022 Negative_regulation of RQCD1 4 0.33 3.18 0.13
43 INT237845 Localization of DCP2 2 0.43 1.16 0.13
44 INT194023 Gene_expression of RQCD1 3 0.52 3.99 0.12
45 INT172100 Binding of TOP1 2 0.14 1.31 0.11
46 INT341192 Phosphorylation of Eif4e 1 0.49 0.36 0.1
47 INT350668 Positive_regulation of Rc3h1 1 0.49 0.79 0.1
48 INT350640 Negative_regulation of Rc3h1 1 0.41 0.73 0.1
49 INT153698 Negative_regulation of Positive_regulation of UPF1 1 0.08 0.72 0.09
50 INT135274 Positive_regulation of RQCD1 2 0.36 1.24 0.08
51 INT303119 Positive_regulation of Tnrc6a 1 0.01 0.74 0.08
52 INT78478 Negative_regulation of TOP1 3 0.21 1.75 0.06
53 INT293912 Protein_catabolism of UPF1 3 0.02 1.2 0.05
54 INT181834 Localization of CNOT1 1 0.73 0.28 0.04
55 INT262691 Positive_regulation of Gene_expression of Caprin1 1 0.08 0.15 0.03
56 INT341167 Negative_regulation of Binding of Eif4e 1 0.33 0.23 0.03
57 INT341200 Negative_regulation of Eif4e 1 0.46 0.14 0.03
58 INT307299 Binding of DCP2 1 0.06 0 0.03
59 INT341189 Positive_regulation of Positive_regulation of Eif4e 1 0.36 0.13 0.03
60 INT227664 Phosphorylation of EIF4E 6 0.46 0.74 0
61 INT217806 Gene_expression of EIF4E 2 0.27 0.68 0
62 INT293778 Positive_regulation of EIF4E 2 0.45 0.42 0
63 INT237848 Positive_regulation of Localization of DCP2 1 0.29 0.94 0
64 INT263602 Negative_regulation of TRIM21 1 0.01 0.28 0
65 INT237844 Gene_expression of DCP2 1 0.39 1.1 0
66 INT245700 Protein_catabolism of CNOT1 1 0.86 0.31 0
67 INT297808 Regulation of Gene_expression of Nanos2 1 0.21 0.58 0
68 INT293768 Regulation of Binding of EIF4E 1 0.18 0.13 0
69 INT297800 Positive_regulation of Nanos2 1 0.41 1.22 0
70 INT341184 Positive_regulation of Localization of Eif4e 1 0.39 0 0
71 INT352833 Binding of Lin28a 1 0.19 0.54 0
72 INT227668 Positive_regulation of Phosphorylation of EIF4E 1 0.20 0.15 0
73 INT310350 Positive_regulation of Positive_regulation of UPF1 1 0.31 0 0
74 INT276879 Regulation of Phosphorylation of EIF4E 1 0.25 0.21 0
75 INT219228 Negative_regulation of Gene_expression of CNOT1 1 0.41 0.43 0
76 INT237841 Positive_regulation of Gene_expression of DCP2 1 0.29 0.3 0
77 INT293780 Positive_regulation of Binding of EIF4E 1 0.20 0.13 0
78 INT297794 Transcription of Nanos2 1 0.61 0.37 0
79 INT341191 Localization of Eif4e 1 0.63 0 0
80 INT307294 Negative_regulation of Binding of DCP2 1 0.05 0 0
81 INT297818 Negative_regulation of Nanos2 1 0.38 0.99 0
82 INT341208 Negative_regulation of Binding of EIF4E 1 0.14 0 0
83 INT310351 Positive_regulation of Binding of UPF1 1 0.31 0 0
84 INT341188 Positive_regulation of Binding of Eif4e 1 0.34 0.18 0
85 INT293775 Regulation of EIF4E 1 0.24 0.64 0
86 INT307298 Regulation of DCP2 1 0.05 0 0
87 INT293761 Negative_regulation of EIF4E 1 0.17 0.85 0
88 INT297788 Gene_expression of Nanos2 1 0.59 4.02 0
89 INT351112 Positive_regulation of Positive_regulation of EIF4E 1 0.45 0.22 0
90 INT297762 Positive_regulation of Gene_expression of Nanos2 1 0.41 1 0
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