GO:0000977

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Name RNA polymerase II regulatory region sequence-specific DNA binding
Categary Function
Go Slim No
Go Link GO:0000977
Unique Molecular Interactions 228
Total Molecular Interactions 277
Total Single Events 2597
Pain Genes Associated 23

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II regulatory region sequence-specific DNA binding. They are ordered first by their pain relevance and then by number of times they were reported for RNA polymerase II regulatory region sequence-specific DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
2 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
3 INT298260 Binding of Runx3 and Pou4f1 1 0.52 2.08 1.22
4 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
5 INT298292 Runx3 Positive_regulation of Gene_expression of Ntrk3 1 0.35 1.36 1.09
6 INT25837 Binding of Dbp and Oprl1 1 0.10 0 1.05
7 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
8 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
9 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
10 INT141276 Negative_regulation of Il18 Negative_regulation of Gene_expression of Hand2 1 0.25 0.8 0.92
11 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
12 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92
13 INT298279 Pou4f1 Positive_regulation of Gene_expression of Runx3 1 0.50 1.31 0.81
14 INT245564 Runx3 Negative_regulation of Ntrk2 3 0.61 1.61 0.79
15 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
16 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69
17 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
18 INT92026 Egr1 Positive_regulation of Fos 1 0.50 0.61 0.67
19 INT226306 CHPT1 Positive_regulation of Localization of DBP 1 0.26 0.65 0.64
20 INT109065 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.00 0 0.58
21 INT261478 Positive_regulation of Ephb1 Regulation of Gene_expression of Egr1 1 0.10 0.23 0.55
22 INT245558 Runx3 Regulation of Ngfr 1 0.06 1 0.53
23 INT200329 Dbp Negative_regulation of Gene_expression of Oprm1 1 0.03 0.07 0.5
24 INT338426 Binding of Hand1 and Hand2 2 0.06 2 0.46
25 INT275549 Il10 Positive_regulation of Localization of Hand2 1 0.01 1.3 0.46
26 INT275550 Hand1 Positive_regulation of Localization of Hand2 1 0.00 1.29 0.46
27 INT298284 Runx3 Negative_regulation of Gene_expression of Ntrk1 1 0.26 0.39 0.43
28 INT298291 Runx3 Negative_regulation of Gene_expression of Ntrk3 1 0.32 0.4 0.43
29 INT298286 Runx3 Regulation of Gene_expression of Runx1 1 0.47 0.36 0.41
30 INT298259 Pou4f1 Negative_regulation of Gene_expression of Runx3 1 0.46 0.58 0.4
31 INT345007 CSF2 Regulation of DBP 1 0.14 0.82 0.39
32 INT130930 Egr1 Negative_regulation of Positive_regulation of Thbs1 1 0.58 0.64 0.38
33 INT298281 Pou4f1 Regulation of Gene_expression of Runx3 1 0.66 0.61 0.37
34 INT345010 GSN Regulation of DBP 1 0.26 0.81 0.36
35 INT345009 DBP Regulation of CCBE1 1 0.00 0.81 0.36
36 INT123495 Negative_regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
37 INT123493 Regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
38 INT90722 Nr4a1 Positive_regulation of Egr1 1 0.20 0.48 0.35
39 INT305853 Polk Regulation of Gene_expression of Hand2 1 0.12 0.93 0.35
40 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35
41 INT90724 Egr3 Positive_regulation of Egr1 1 0.33 0.48 0.35
42 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34
43 INT95552 Binding of Dbp and Shbg 3 0.01 2.09 0.32
44 INT266806 Hand2 Regulation of Gene_expression of IL10 1 0.00 1.23 0.32
45 INT241139 Ighg1 Positive_regulation of Hand2 1 0.06 0.65 0.32
46 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32
47 INT298285 Pou4f1 Positive_regulation of Runx3 1 0.50 0.56 0.32
48 INT181433 Hand2 Regulation of Gene_expression of Ccl2 1 0.12 0.68 0.32
49 INT298269 Positive_regulation of Pou4f1 Positive_regulation of Runx3 1 0.50 0.56 0.32
50 INT266804 Hand2 Regulation of Gene_expression of IL13 1 0.00 1.23 0.32
51 INT266805 Hand2 Regulation of Gene_expression of IL4 1 0.00 1.23 0.32
52 INT126097 Ddc Positive_regulation of Egr1 1 0.08 0 0.32
53 INT99154 Binding of DBP and SIL1 1 0.02 0.16 0.31
54 INT253073 Il4 Positive_regulation of Hand2 1 0.10 0.59 0.31
55 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3
56 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3
57 INT93988 Rab8a Regulation of Hand2 1 0.09 0.78 0.3
58 INT245562 Ntrk3 Regulation of Runx3 1 0.40 0.77 0.29
59 INT74334 Penk Regulation of Transcription of Egr1 1 0.40 0.25 0.29
60 INT181442 Ccl2 Positive_regulation of Localization of Hand2 1 0.26 0.63 0.29
61 INT74336 Crh Regulation of Transcription of Egr1 1 0.49 0.24 0.28
62 INT147356 Egr1 Positive_regulation of Gene_expression of Btg1 1 0.14 1.56 0.28
63 INT185076 Bpifa2 Positive_regulation of Hand2 1 0.16 0.36 0.28
64 INT278209 Ciita Regulation of Hand2 1 0.36 1.53 0.28
65 INT194821 MAPK1 Regulation of Hand2 1 0.03 1.27 0.28
66 INT147358 Egr1 Positive_regulation of Gene_expression of Gdf15 1 0.14 1.56 0.28
67 INT278216 Ciita Regulation of Gene_expression of Hand2 1 0.36 1.53 0.28
68 INT58182 Fos Regulation of Egr1 1 0.49 0.09 0.27
69 INT246442 Hand2 Positive_regulation of Gene_expression of Cd79a 1 0.03 0.78 0.27
70 INT147359 Positive_regulation of Pik3cd Positive_regulation of Egr1 1 0.09 1.51 0.27
71 INT130931 Sis Negative_regulation of Egr1 1 0.01 0.52 0.27
72 INT58176 Junb Regulation of Egr1 1 0.46 0.09 0.27
73 INT147360 Pik3cd Positive_regulation of Egr1 1 0.12 1.51 0.27
74 INT305849 Polk Positive_regulation of Gene_expression of Hand2 1 0.08 0.76 0.27
75 INT226537 Hand2 Positive_regulation of IL22 1 0.02 0.86 0.26
76 INT12629 Binding of Dbp and Cish 1 0.03 0 0.25
77 INT118418 Gata1 Positive_regulation of Transcription of Tac2 1 0.61 0.77 0.25
78 INT118419 Binding of Gata1 and Tac2 1 0.31 0.7 0.24
79 INT130060 PPARG Positive_regulation of Positive_regulation of Egr1 1 0.22 0.46 0.24
80 INT89708 Binding of Dbp and Mir377 1 0.02 0 0.23
81 INT184162 Egr1 Positive_regulation of Transcription of Ptges2 1 0.08 0.42 0.22
82 INT184160 Binding of Egr1 and Ptges2 1 0.07 0.4 0.22
83 INT221781 Camk4 Positive_regulation of Mef2d 1 0.28 0.14 0.22
84 INT298275 Binding of Runx3 and Ntrk2 1 0.37 0.16 0.21
85 INT195212 Binding of CCR4 and Hand2 1 0.03 0.46 0.21
86 INT271853 Ngf Positive_regulation of Gene_expression of Egr1 1 0.53 1.36 0.21
87 INT259817 Ltp Positive_regulation of Egr1 1 0.03 0.28 0.2
88 INT226511 Gene_expression of Il25 Positive_regulation of Gene_expression of Hand2 1 0.01 0.95 0.2
89 INT200340 Dbp Negative_regulation of Oprm1 1 0.03 0.06 0.2
90 INT226514 BTPs Negative_regulation of Gene_expression of Hand2 1 0.03 0.22 0.2
91 INT338767 Positive_regulation of Binding of Hand1 and Hand2 1 0.07 0.5 0.2
92 INT226510 BTPs Negative_regulation of Hand2 1 0.03 0.22 0.2
93 INT175464 Hand2 Positive_regulation of Gene_expression of Sftpd 1 0.19 1.05 0.2
94 INT259812 Gtf3a Regulation of Egr1 1 0.01 0.58 0.19
95 INT298294 Gene_expression of Runx3 Negative_regulation of Ntrk2 1 0.39 0.16 0.19
96 INT310498 Gene_expression of Neurog2 Positive_regulation of Positive_regulation of Eomes 1 0.20 0.42 0.19
97 INT184159 Egr1 Positive_regulation of Ptges2 1 0.07 0.34 0.19
98 INT58178 Gtf3a Positive_regulation of Egr1 1 0.07 0.09 0.19
99 INT184161 Negative_regulation of Egr1 Positive_regulation of Ptges2 1 0.07 0.34 0.19
100 INT228737 Rae1 Negative_regulation of Hand2 1 0.08 1.07 0.19
101 INT259814 Binding of Arc and Egr1 1 0.34 0.55 0.19
102 INT259813 Binding of Egr1 and Arc 1 0.32 0.55 0.19
103 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19
104 INT58181 Gtf3a Positive_regulation of Gene_expression of Egr1 1 0.07 0.1 0.19
105 INT316748 IL18 Positive_regulation of Regulation of Hand2 1 0.14 1.11 0.18
106 INT200343 Dbp Regulation of Gene_expression of Oprm1 1 0.02 0.07 0.18
107 INT329843 Il4 Regulation of Hand2 1 0.04 0.87 0.18
108 INT317895 Fos Regulation of Transcription of Egr1 1 0.41 1.03 0.17
109 INT181457 Binding of CCL16 and Hand2 1 0.04 0.92 0.17
110 INT317897 Egr1 Regulation of Transcription of Fosb 1 0.34 1.08 0.17
111 INT317892 Egr1 Regulation of Transcription of Fos 1 0.41 1.03 0.17
112 INT298288 Negative_regulation of Runx3 Positive_regulation of Negative_regulation of Ntrk3 1 0.35 0.27 0.17
113 INT149281 Binding of MAPT and Dbp 1 0.00 0.4 0.17
114 INT298265 Runx3 Negative_regulation of Gene_expression of Ntrk2 1 0.61 0.25 0.17
115 INT190635 Binding of Lmo2 and Nr1h2 1 0.09 0.59 0.16
116 INT190629 Binding of Lmo2 and Usf1 1 0.11 0.6 0.16
117 INT245569 Runx3 Regulation of Gtf3a 1 0.01 0.65 0.16
118 INT30709 Negative_regulation of Binding of Dbp and Gpi 1 0.00 0 0.16
119 INT190634 Binding of Lmo2 and Maz 1 0.14 0.59 0.16
120 INT30708 Binding of Dbp and Gpi 1 0.00 0 0.16
121 INT245559 Runx3 Regulation of Runx1 1 0.31 0.63 0.16
122 INT190633 Binding of Lmo2 and Deaf1 1 0.18 0.59 0.16
123 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15
124 INT294766 Cerk Regulation of Gene_expression of Hand2 1 0.13 0.32 0.15
125 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15
126 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15
127 INT168806 Tlr4 Positive_regulation of Gene_expression of Egr1 1 0.18 0.3 0.15
128 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15
129 INT347012 Hand2 Positive_regulation of Il4 1 0.01 0 0.14
130 INT347015 Hand2 Regulation of Cd86 1 0.06 0 0.14
131 INT294764 Binding of Hand2 and Cerk 1 0.17 0.31 0.14
132 INT235546 Stat6 Positive_regulation of Positive_regulation of Hand2 1 0.02 0.9 0.14
133 INT347018 Cd80 Regulation of Hand2 1 0.03 0.05 0.13
134 INT247267 Binding of Egr1 and Mecp2 1 0.12 0.18 0.13
135 INT347007 Cd86 Regulation of Hand2 1 0.06 0.05 0.13
136 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13
137 INT296080 TGFB1 Regulation of Hand2 1 0.01 1 0.12
138 INT220527 Nme1 Negative_regulation of Positive_regulation of Vegfa 1 0.00 1.23 0.12
139 INT294760 Cerk Positive_regulation of Hand2 1 0.23 0.16 0.12
140 INT54543 DBP Regulation of PENK 1 0.28 0 0.12
141 INT253077 Prok2 Regulation of Gene_expression of Hand2 1 0.10 0.11 0.12
142 INT294758 Regulation of Cerk Positive_regulation of Hand2 1 0.21 0.16 0.12
143 INT228746 Hspa9 Negative_regulation of Positive_regulation of Hand2 1 0.11 0.31 0.11
144 INT228760 Rae1 Negative_regulation of Positive_regulation of Hand2 1 0.08 0.31 0.11
145 INT175463 Sftpd Negative_regulation of Gene_expression of Hand2 1 0.17 0.96 0.11
146 INT65644 Binding of AFA and Dbp 1 0.10 0.86 0.1
147 INT263495 Hand1 Regulation of Localization of Hand2 1 0.12 0.5 0.09
148 INT263496 Hand2 Regulation of Localization of Hand1 1 0.12 0.5 0.09
149 INT201349 Binding of Hand2 and Il4 1 0.17 0.67 0.09
150 INT238628 Mef2c Regulation of Gene_expression of Arc 1 0.09 0.16 0.08
151 INT238625 Mef2c Regulation of Gene_expression of Syngap1 1 0.10 0.16 0.08
152 INT220697 Binding of CHRNE and DBP 1 0.02 1.15 0.08
153 INT178078 Positive_regulation of Binding of DBP and HIF1A 1 0.00 1 0.08
154 INT178103 Binding of DBP and HIF1A 1 0.00 0.99 0.07
155 INT267016 Bdnf Positive_regulation of Egr1 1 0.12 0.09 0.07
156 INT286298 Binding of Hand2 and Negative_regulation of Gene_expression of Il12a 1 0.07 0.3 0.07
157 INT118417 Gata1 Regulation of Gene_expression of Serpinb9g 1 0.17 0.12 0.06
158 INT298258 Binding of Runx3 and Stub1 1 0.11 0.18 0.06
159 INT278454 CSF2 Regulation of Hand2 1 0.02 0.66 0.05
160 INT181814 Gsk3b Regulation of Gata4 1 0.06 0.37 0.05
161 INT278208 Ciita Negative_regulation of Gene_expression of Hand2 1 0.34 0.7 0.05
162 INT342581 Binding of Dbp and Pth 1 0.04 2.12 0.04
163 INT347020 Hand2 Regulation of Gene_expression of Cd86 1 0.08 0.19 0.04
164 INT60221 Agt Regulation of Gene_expression of Egr1 1 0.42 0 0.04
165 INT347009 Hand2 Regulation of Gene_expression of Il4 1 0.01 0.19 0.04
166 INT243766 Binding of Egr1 and Proc 1 0.01 0.2 0.03
167 INT278291 Binding of CRP and DBP 1 0.12 1.57 0.03
168 INT278289 Binding of DBP and ESR1 1 0.03 0.82 0.03
169 INT290437 Gene_expression of Mef2c Negative_regulation of Upf1 1 0.02 0.25 0.03
170 INT278293 Binding of DBP and SHBG 2 0.02 1.34 0
171 INT213549 Phox2b Regulation of Transcription of Phox2a 1 0.44 0.17 0
172 INT213552 Gene_expression of Phox2a Positive_regulation of Gene_expression of Phox2b 1 0.45 0.17 0
173 INT305845 Polk Positive_regulation of Regulation of Hand2 1 0.08 0.34 0
174 INT278295 DBP Positive_regulation of SHBG 1 0.02 0.92 0
175 INT314693 Binding of TBX2 and TBX5 1 0.16 0.84 0
176 INT325099 Dbp Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.00 0.14 0
177 INT270732 DBP Negative_regulation of SHBG 1 0.00 1.08 0
178 INT332409 Egr1 Regulation of Hgf 1 0.26 0.14 0
179 INT213557 Neurog2 Regulation of Transcription of Phox2b 1 0.44 0.17 0
180 INT272513 Binding of Mef2a and Eif2s2 1 0.03 0 0
181 INT240122 Nab2 Regulation of Egr1 1 0.09 0.59 0
182 INT332408 Binding of Egr1 and Hgf 1 0.35 0.14 0
183 INT273949 Binding of Crem and Smarca4 1 0.01 0 0
184 INT297209 Myoz1 Regulation of Mef2a 1 0.04 0.09 0
185 INT350706 Binding of Mef2c and Mir223 1 0.02 0.11 0
186 INT243770 Egr1 Regulation of Nab2 1 0.28 0.09 0
187 INT290439 Negative_regulation of Mef2c Positive_regulation of Gene_expression of Ppargc1a 1 0.21 0 0
188 INT184137 Binding of Socs5 and Regulation of Hand2 1 0.09 1.01 0
189 INT226307 DBP Positive_regulation of Binding of CHPT1 1 0.26 0 0
190 INT290441 Mef2c Regulation of Mef2b 1 0.09 0.11 0
191 INT213175 Binding of DBP and HP 1 0.03 1.08 0
192 INT213548 Neurog2 Regulation of Transcription of Phox2a 1 0.45 0.17 0
193 INT297213 Myoz1 Regulation of Mef2c 1 0.02 0.09 0
194 INT259811 Narp Positive_regulation of Gene_expression of Egr1 1 0.26 0.86 0
195 INT290438 Mef2c Regulation of Mef2a 1 0.26 0.11 0
196 INT274434 Binding of Gata4 and Zfpm2 1 0.12 0.56 0
197 INT351982 Smarca4 Positive_regulation of Stk11 1 0.05 0.58 0
198 INT147017 Binding of DBP and Shbg 1 0.10 0 0
199 INT223581 TXK Negative_regulation of DBP 1 0.00 0.47 0
200 INT211573 Positive_regulation of Binding of Dbp and Stip1 1 0.00 0.38 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II regulatory region sequence-specific DNA binding. They are ordered first by their pain relevance and then by number of times they were reported in RNA polymerase II regulatory region sequence-specific DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
2 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
3 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
4 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
5 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95
6 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
7 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
8 INT2758 Binding of Dbp 36 0.44 8.3 14.47
9 INT57878 Positive_regulation of Gene_expression of Egr1 36 0.70 20.42 14.45
10 INT173505 Localization of Hand2 63 0.57 45.32 13.66
11 INT203490 Gene_expression of Runx3 19 0.76 27.56 12.57
12 INT57876 Positive_regulation of Egr1 46 0.70 25.6 9.41
13 INT25834 Positive_regulation of Dbp 59 0.68 24.34 9.32
14 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28
15 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24
16 INT8637 Negative_regulation of Dbp 112 0.50 33.28 8.4
17 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
18 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
19 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
20 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01
21 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38
22 INT21103 Gene_expression of Dbp 48 0.61 22.6 5.59
23 INT47704 Regulation of Egr1 17 0.60 2.43 5.18
24 INT47706 Negative_regulation of Positive_regulation of Egr1 9 0.41 6.11 5.1
25 INT51944 Positive_regulation of Transcription of Egr1 12 0.49 1.96 4.72
26 INT48747 Positive_regulation of Dbp 7 0.24 1.28 4.69
27 INT29231 Regulation of Dbp 44 0.53 10.08 4.47
28 INT94466 Regulation of Gene_expression of Hand2 14 0.28 7.97 4.46
29 INT117936 Regulation of Gene_expression of Egr1 18 0.60 9.37 4.45
30 INT5219 Negative_regulation of DBP 43 0.57 23.35 4.26
31 INT9098 Positive_regulation of DBP 30 0.69 15.77 4.26
32 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
33 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
34 INT156131 Binding of Hand2 14 0.25 10.35 3.99
35 INT123502 Binding of Egr1 11 0.35 6.7 3.77
36 INT12598 Binding of DBP 20 0.48 13.11 3.62
37 INT66191 Gene_expression of DBP 42 0.66 22.25 3.18
38 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
39 INT203441 Positive_regulation of Gene_expression of Runx3 4 0.66 4.35 2.49
40 INT96640 Negative_regulation of Gene_expression of Egr1 13 0.43 7.22 2.48
41 INT74262 Negative_regulation of Egr1 15 0.57 7.51 2.41
42 INT15243 Regulation of Egr1 19 0.61 7.6 2.13
43 INT80599 Regulation of Positive_regulation of Egr1 3 0.28 0.46 2.09
44 INT129239 Positive_regulation of Positive_regulation of Hand2 5 0.43 2.81 1.93
45 INT100064 Regulation of DBP 17 0.45 6.06 1.85
46 INT28173 Localization of DBP 8 0.73 3.4 1.83
47 INT149812 Gene_expression of Dbp 6 0.39 1.47 1.79
48 INT57875 Positive_regulation of Positive_regulation of Egr1 6 0.49 2.74 1.75
49 INT118412 Gene_expression of Gata1 5 0.62 0.83 1.6
50 INT57877 Negative_regulation of Positive_regulation of Egr1 4 0.42 1.63 1.57
51 INT118413 Positive_regulation of Gene_expression of Gata1 3 0.40 0.68 1.56
52 INT89871 Gene_expression of Gata4 11 0.69 1.05 1.53
53 INT245537 Negative_regulation of Runx3 4 0.56 4 1.53
54 INT100672 Transcription of Hand2 9 0.42 2.84 1.47
55 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
56 INT298250 Negative_regulation of Gene_expression of Runx3 1 0.56 1.92 1.45
57 INT53003 Positive_regulation of Positive_regulation of Egr1 6 0.64 2.36 1.44
58 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
59 INT116008 Binding of Gata3 2 0.34 1.37 1.41
60 INT141344 Transcription of Egr1 11 0.70 5.59 1.34
61 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
62 INT175452 Negative_regulation of Positive_regulation of Hand2 4 0.21 3.78 1.21
63 INT169251 Gene_expression of Phox2b 9 0.70 3.88 1.17
64 INT147213 Negative_regulation of Gene_expression of Dbp 5 0.34 2.88 1.16
65 INT123503 Positive_regulation of Binding of Egr1 3 0.13 2.34 1.04
66 INT109069 Transcription of Gata4 4 0.64 0.52 1.01
67 INT109070 Positive_regulation of Transcription of Gata4 1 0.03 0 1.01
68 INT123501 Negative_regulation of Binding of Egr1 2 0.12 2.04 0.99
69 INT235516 Positive_regulation of Localization of Hand2 4 0.36 3.04 0.97
70 INT226419 Negative_regulation of Localization of Hand2 4 0.30 3.17 0.96
71 INT51947 Regulation of Transcription of Egr1 2 0.59 0.15 0.96
72 INT31281 Binding of Dbp 4 0.19 1.28 0.88
73 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
74 INT112014 Negative_regulation of Regulation of Hand2 3 0.34 2.07 0.86
75 INT298253 Regulation of Gene_expression of Runx3 1 0.59 1.21 0.85
76 INT245539 Positive_regulation of Runx3 4 0.49 3.11 0.79
77 INT149820 Regulation of Dbp 2 0.26 0.17 0.77
78 INT13826 Positive_regulation of Negative_regulation of Dbp 5 0.42 2.19 0.74
79 INT116012 Regulation of Positive_regulation of Gata3 1 0.20 0.07 0.71
80 INT144995 Positive_regulation of Gata1 1 0.37 0.14 0.71
81 INT6050 Localization of Egr1 4 0.68 0.53 0.7
82 INT245535 Transcription of Runx3 3 0.71 2.03 0.7
83 INT109787 Protein_catabolism of Dbp 2 0.56 0 0.7
84 INT116006 Positive_regulation of Transcription of Gata3 1 0.21 0.07 0.7
85 INT116010 Positive_regulation of Binding of Gata3 1 0.31 0.07 0.7
86 INT149803 Regulation of Gene_expression of Dbp 1 0.26 0 0.7
87 INT47021 Positive_regulation of Positive_regulation of DBP 2 0.19 1.06 0.69
88 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67
89 INT141341 Binding of Egr1 5 0.48 2.65 0.67
90 INT271488 Negative_regulation of Negative_regulation of Hand2 3 0.18 2.36 0.67
91 INT102686 Phosphorylation of Egr1 3 0.59 2.57 0.64
92 INT202416 Negative_regulation of Gata3 2 0.32 1.17 0.64
93 INT89867 Negative_regulation of Gene_expression of Gata4 3 0.38 0.17 0.61
94 INT290660 Negative_regulation of Gene_expression of Gata3 1 0.25 1.52 0.6
95 INT132588 Positive_regulation of Negative_regulation of Hand2 1 0.03 0.47 0.58
96 INT89868 Negative_regulation of Gata4 1 0.38 0 0.57
97 INT325080 Positive_regulation of Gene_expression of Dbp 1 0.19 0.37 0.55
98 INT81061 Regulation of Negative_regulation of Egr1 1 0.22 0 0.53
99 INT200247 Negative_regulation of Dbp 5 0.15 0.8 0.5
100 INT213535 Transcription of Phox2b 3 0.62 2.69 0.49
101 INT168801 Localization of Egr1 4 0.78 0.7 0.48
102 INT238081 Regulation of Protein_catabolism of Dbp 1 0.00 0 0.46
103 INT141342 Negative_regulation of Transcription of Egr1 4 0.43 2.39 0.45
104 INT325217 Regulation of Positive_regulation of Hand2 1 0.21 0.32 0.41
105 INT243756 Regulation of Positive_regulation of Egr1 7 0.45 1.18 0.4
106 INT245531 Binding of Runx3 2 0.46 1.12 0.39
107 INT194745 Regulation of Regulation of Hand2 1 0.03 0.95 0.39
108 INT55367 Localization of Dbp 18 0.70 7.43 0.38
109 INT226424 Negative_regulation of Transcription of Hand2 1 0.08 0.66 0.37
110 INT194546 Positive_regulation of Gene_expression of Dbp 9 0.28 2.93 0.36
111 INT19294 Transcription of Dbp 2 0.33 0.19 0.34
112 INT238560 Regulation of Mef2c 9 0.45 2.12 0.33
113 INT109058 Positive_regulation of Gene_expression of Gata4 2 0.29 0 0.33
114 INT188498 Negative_regulation of Transcription of Egr1 3 0.41 0.14 0.32
115 INT298247 Positive_regulation of Transcription of Runx3 1 0.66 0.53 0.32
116 INT226394 Regulation of Phosphorylation of Hand2 1 0.05 0.97 0.28
117 INT245521 Regulation of Runx3 1 0.23 0.76 0.28
118 INT109788 Positive_regulation of Positive_regulation of Dbp 1 0.40 0 0.24
119 INT141343 Positive_regulation of Transcription of Egr1 1 0.47 1.43 0.24
120 INT100671 Positive_regulation of Transcription of Hand2 2 0.36 0.81 0.23
121 INT226390 Phosphorylation of Hand2 1 0.14 0.85 0.22
122 INT202355 Transcription of Mef2c 3 0.69 0.6 0.21
123 INT263492 Positive_regulation of Regulation of Hand2 3 0.19 4.76 0.21
124 INT213524 Transcription of Phox2a 2 0.64 0.29 0.21
125 INT346813 Positive_regulation of Regulation of Egr1 1 0.49 0.27 0.21
126 INT213243 Negative_regulation of Gene_expression of DBP 7 0.42 2.68 0.2
127 INT220488 Gene_expression of Nme1 1 0.01 2.44 0.2
128 INT310483 Positive_regulation of Eomes 2 0.38 0.85 0.19
129 INT310478 Positive_regulation of Transcription of Eomes 1 0.23 0.42 0.19
130 INT310466 Positive_regulation of Positive_regulation of Eomes 1 0.23 0.42 0.19
131 INT248543 Positive_regulation of Mef2c 7 0.69 2.82 0.18
132 INT170390 Transcription of Eomes 2 0.31 0.51 0.18
133 INT284888 Regulation of Transcription of Hand2 1 0.16 0.32 0.18
134 INT190551 Localization of Lmo2 1 0.21 0.6 0.17
135 INT102793 Regulation of Phosphorylation of Egr1 1 0.33 0 0.17
136 INT245527 Negative_regulation of Transcription of Runx3 1 0.42 0.59 0.17
137 INT251938 Positive_regulation of Gene_expression of MEF2A 1 0.12 0.14 0.17
138 INT277602 Binding of Mef2c 10 0.39 4.35 0.16
139 INT251939 Gene_expression of MEF2A 1 0.18 0.14 0.16
140 INT310481 Regulation of Eomes 1 0.28 0.1 0.15
141 INT220570 Transcription of Gata1 2 0.05 0.91 0.14
142 INT249108 Regulation of MEF2A 1 0.17 0.28 0.14
143 INT194746 Phosphorylation of Gata3 1 0.10 0.08 0.12
144 INT213201 Negative_regulation of Positive_regulation of Dbp 1 0.13 0.33 0.12
145 INT220490 Positive_regulation of Nme1 1 0.01 2.57 0.12
146 INT200263 Negative_regulation of Negative_regulation of Dbp 1 0.02 0.1 0.12
147 INT190566 Gene_expression of Lmo2 1 0.43 0.9 0.12
148 INT346814 Phosphorylation of Egr1 1 0.62 0 0.12
149 INT294379 Phosphorylation of Mef2a 1 0.56 0 0.1
150 INT294371 Positive_regulation of Phosphorylation of Mef2a 1 0.42 0 0.1
151 INT345019 Negative_regulation of Binding of DBP 1 0.36 0.75 0.1
152 INT213513 Gene_expression of Phox2a 1 0.72 0.51 0.09
153 INT346807 Regulation of Transcription of Egr1 1 0.44 0.27 0.09
154 INT161215 Regulation of Gene_expression of Dbp 1 0.12 0.94 0.09
155 INT290404 Positive_regulation of Negative_regulation of Mef2c 1 0.50 0.72 0.08
156 INT277578 Regulation of Negative_regulation of Mef2c 2 0.45 1.17 0.07
157 INT290401 Gene_expression of Mef2a 1 0.64 1.81 0.07
158 INT213126 Phosphorylation of Dbp 1 0.12 0.48 0.07
159 INT241491 Positive_regulation of Regulation of Dbp 1 0.05 0.13 0.07
160 INT290417 Positive_regulation of Gene_expression of Mef2c 1 0.50 1.25 0.06
161 INT213532 Negative_regulation of Gene_expression of Phox2b 1 0.39 0.1 0.05
162 INT213536 Negative_regulation of Gene_expression of Phox2a 1 0.39 0.1 0.05
163 INT213244 Positive_regulation of Gene_expression of DBP 4 0.22 1.99 0.04
164 INT213521 Positive_regulation of Gene_expression of Phox2a 1 0.64 0.24 0.04
165 INT290407 Positive_regulation of Binding of Mef2c 1 0.44 0.93 0.04
166 INT213202 Positive_regulation of Localization of Dbp 1 0.13 0 0.04
167 INT248540 Positive_regulation of Gata4 2 0.23 0.95 0.03
168 INT170377 Gene_expression of Eomes 2 0.42 0.37 0.03
169 INT260908 Positive_regulation of Smarca4 2 0.21 0.53 0.03
170 INT192401 Positive_regulation of Binding of Hand2 1 0.08 0 0.03
171 INT213514 Regulation of Gene_expression of Phox2b 1 0.56 0.23 0.03
172 INT336415 Positive_regulation of Gene_expression of Eomes 1 0.38 0.17 0.03
173 INT290419 Regulation of Gene_expression of Mef2c 1 0.62 0.41 0.03
174 INT213539 Regulation of Phox2b 1 0.11 0.23 0.03
175 INT290399 Negative_regulation of Gene_expression of Mef2c 1 0.59 0.59 0.03
176 INT290421 Transcription of Mef2d 1 0.52 0 0.03
177 INT262960 Gene_expression of TBX5 1 0.23 0.09 0.03
178 INT290426 Positive_regulation of Mef2a 1 0.38 0.46 0.03
179 INT213518 Regulation of Gene_expression of Phox2a 1 0.57 0.35 0.03
180 INT290422 Transcription of Mef2a 1 0.65 0 0.03
181 INT272480 Negative_regulation of Mef2a 2 0.40 0 0
182 INT274404 Binding of Gata4 2 0.16 0.89 0
183 INT336412 Negative_regulation of Gene_expression of Eomes 1 0.23 0.11 0
184 INT298238 Localization of Runx3 1 0.71 0.77 0
185 INT325081 Localization of Dbp 1 0.30 0.34 0
186 INT320531 Transcription of MEF2A 1 0.23 1.54 0
187 INT310430 Transcription of DBP 1 0.06 0 0
188 INT290405 Regulation of Gene_expression of Mef2a 1 0.43 0.06 0
189 INT213508 Positive_regulation of Gene_expression of Phox2b 1 0.45 0.17 0
190 INT290400 Regulation of Regulation of Mef2c 1 0.45 0.24 0
191 INT323288 Regulation of Gene_expression of DBP 1 0.19 0.25 0
192 INT290429 Negative_regulation of Negative_regulation of Mef2c 1 0.37 0.05 0
193 INT272473 Negative_regulation of Localization of Mef2a 1 0.23 0.41 0
194 INT353127 Negative_regulation of Negative_regulation of DBP 1 0.16 0.47 0
195 INT346703 Regulation of Negative_regulation of Dbp 1 0.27 0.15 0
196 INT290425 Negative_regulation of Binding of Mef2c 1 0.37 0 0
197 INT285638 Regulation of Negative_regulation of Egr1 1 0.37 0.14 0
198 INT323287 Positive_regulation of Negative_regulation of DBP 1 0.22 0.19 0
199 INT290409 Negative_regulation of Transcription of Mef2c 1 0.43 0.08 0
200 INT229709 Negative_regulation of Localization of Dbp 1 0.20 0.06 0
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