GO:0000978

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Name RNA polymerase II core promoter proximal region sequence-specific DNA binding
Categary Function
Go Slim No
Go Link GO:0000978
Unique Molecular Interactions 250
Total Molecular Interactions 303
Total Single Events 2188
Pain Genes Associated 31

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II core promoter proximal region sequence-specific DNA binding. They are ordered first by their pain relevance and then by number of times they were reported for RNA polymerase II core promoter proximal region sequence-specific DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
2 INT249002 Gabrg1 Positive_regulation of Protein_catabolism of Per1 1 0.35 0.09 1.15
3 INT134970 Positive_regulation of Binding of OPRK1 and SP1 1 0.00 0 1.05
4 INT134969 Binding of OPRK1 and SP1 1 0.00 0 1.04
5 INT77254 Binding of gr and Sp1 1 0.04 0.4 0.9
6 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88
7 INT172982 Binding of MUC1 and MUC4 1 0.30 2.46 0.78
8 INT190986 Per1 Positive_regulation of Scn2a1 1 0.17 0 0.74
9 INT157539 Binding of SP1 and Regulation of Gene_expression of OPRM1 1 0.36 1.2 0.72
10 INT98956 Positive_regulation of Binding of NR5A2 and SP1 1 0.00 0 0.7
11 INT207542 Sp1 Regulation of Oprm1 1 0.15 0.06 0.7
12 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
13 INT98958 Binding of NR5A2 and SP1 1 0.00 0 0.7
14 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
15 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
16 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
17 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
18 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
19 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
20 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
21 INT249010 Gabrg1 Regulation of Positive_regulation of Per1 1 0.33 0 0.67
22 INT207547 Sp1 Regulation of Qsox1 1 0.05 0.06 0.67
23 INT249008 Gabrg1 Regulation of Per1 1 0.33 0 0.67
24 INT132154 PSG7 Positive_regulation of Localization of MUC1 1 0.00 0 0.65
25 INT148773 Binding of Calca and Usf2 1 0.46 0.42 0.64
26 INT148776 Binding of Usf2 and Rtn1 1 0.38 0.42 0.64
27 INT123416 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.60 0 0.63
28 INT148780 Binding of Usf2 and Usf1 1 0.40 0.41 0.62
29 INT98953 Positive_regulation of Binding of SP1 and CFHR4 1 0.00 0 0.62
30 INT98954 Binding of SP1 and CFHR4 1 0.00 0 0.61
31 INT148771 Usf2 Negative_regulation of Calca 1 0.42 0.4 0.59
32 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
33 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
34 INT249024 Gabrg1 Positive_regulation of Transcription of Per1 1 0.59 0 0.55
35 INT249020 Gabrg1 Positive_regulation of Per1 1 0.40 0 0.55
36 INT248997 Gabrg1 Positive_regulation of Clock 1 0.37 0 0.54
37 INT248995 Gabrg1 Regulation of Transcription of Clock 1 0.36 0 0.54
38 INT249016 Gabrg1 Positive_regulation of Transcription of Clock 1 0.37 0 0.54
39 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
40 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
41 INT304576 Binding of Arntl and Clock 6 0.37 0.43 0.5
42 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
43 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
44 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
45 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
46 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
47 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
48 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
49 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
50 INT249011 Gabrg1 Regulation of Clock 1 0.19 0 0.43
51 INT89332 Binding of SP1 and SP3 1 0.30 0.76 0.39
52 INT337890 Per1 Regulation of Nr2f2 1 0.08 0 0.37
53 INT249004 Helt Regulation of Clock 1 0.01 0.09 0.37
54 INT249015 Regulation of Helt Regulation of Clock 1 0.01 0.09 0.37
55 INT167558 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.03 0.07 0.36
56 INT200333 Binding of Rest and Sp1 1 0.24 0.07 0.35
57 INT200316 Sp1 Regulation of Gene_expression of Rest 1 0.31 0 0.35
58 INT132174 PSG7 Positive_regulation of Gene_expression of Muc1 1 0.00 0 0.34
59 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
60 INT132169 PSG7 Positive_regulation of Muc1 1 0.00 0 0.34
61 INT132155 PSG7 Positive_regulation of Gene_expression of MUC1 1 0.00 0 0.32
62 INT200351 Sp1 Positive_regulation of Gene_expression of Rest 1 0.34 0.07 0.3
63 INT190826 ELANE Positive_regulation of Localization of MUC1 1 0.07 0 0.29
64 INT128046 Per1 Regulation of Fos 1 0.41 0 0.29
65 INT128048 Per1 Regulation of Gene_expression of Fos 1 0.41 0 0.29
66 INT148774 Usf2 Regulation of Calca 1 0.11 0.24 0.27
67 INT190983 Vip Positive_regulation of Gene_expression of Per1 1 0.13 0.51 0.27
68 INT96789 Binding of SP1 and NR2F2 1 0.24 0.27 0.27
69 INT96787 SP1 Positive_regulation of GDF15 1 0.08 0.27 0.27
70 INT190996 ADCYAP1 Positive_regulation of Per1 1 0.06 0.45 0.27
71 INT125515 SP1 Regulation of GDF15 1 0.14 0.47 0.26
72 INT169837 Sp1 Positive_regulation of Gene_expression of Kcnq3 1 0.04 0.08 0.26
73 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26
74 INT169836 Sp1 Positive_regulation of Gene_expression of Kcnq2 1 0.05 0.08 0.26
75 INT118418 Gata1 Positive_regulation of Transcription of Tac2 1 0.61 0.77 0.25
76 INT260739 Mapk14 Regulation of Positive_regulation of Sp1 1 0.01 1.06 0.25
77 INT213813 Binding of Tcf4 and Tfeb 1 0.14 0.81 0.24
78 INT118419 Binding of Gata1 and Tac2 1 0.31 0.7 0.24
79 INT256656 Binding of EP300 and HHIP 1 0.22 0 0.24
80 INT147590 Binding of Muc1 and Mag 1 0.26 3.29 0.23
81 INT213805 Binding of Tcf12 and Tcf4 1 0.00 0.79 0.23
82 INT190827 KCNA1 Regulation of Localization of MUC1 1 0.05 0.08 0.22
83 INT189196 RASGRP1 Positive_regulation of SP1 1 0.05 0.63 0.21
84 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19
85 INT203532 Negative_regulation of Pou4f1 Negative_regulation of Gene_expression of Pou4f2 1 0.34 0.44 0.19
86 INT136462 Negative_regulation of Ptgs1 Negative_regulation of Gene_expression of Sp1 1 0.01 0.65 0.19
87 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19
88 INT318188 MUC5AC Positive_regulation of MUC1 1 0.16 1.12 0.17
89 INT119267 Binding of EP300 and PPM1E 1 0.01 0.46 0.17
90 INT244116 ELAVL3 Negative_regulation of MUC1 1 0.09 3.41 0.15
91 INT243524 Positive_regulation of Binding of NTF3 and SOX10 1 0.01 0.54 0.14
92 INT243525 Binding of NTF3 and SOX10 1 0.01 0.54 0.14
93 INT253564 Binding of Lpl and Sp1 1 0.13 0.9 0.14
94 INT185455 MUC1 Negative_regulation of Timp1 1 0.06 0.84 0.13
95 INT185416 MUC1 Negative_regulation of TIMP1 1 0.18 0.84 0.13
96 INT200315 Binding of Sp1 and Sp3 1 0.29 0 0.12
97 INT68802 Sp1 Regulation of Gene_expression of Pebp1 1 0.24 0 0.12
98 INT319731 Ep300 Positive_regulation of Binding of Rela 1 0.01 0.37 0.12
99 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11
100 INT334871 Binding of Mpz and Sox10 1 0.13 0 0.11
101 INT253572 Binding of Csnk2a2 and Sp1 1 0.17 0 0.11
102 INT334862 Positive_regulation of Binding of Mpz and Sox10 1 0.17 0 0.11
103 INT281022 Clock Negative_regulation of Per1 1 0.26 0.09 0.11
104 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11
105 INT281023 Clock Negative_regulation of Per2 1 0.31 0.09 0.11
106 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11
107 INT171163 Creb1 Regulation of Sp1 1 0.03 0.62 0.1
108 INT194822 Negative_regulation of MAPK1 Negative_regulation of Binding of Sp1 1 0.04 0.05 0.1
109 INT147671 Tg(CAG-EGFP)D4Nagy Positive_regulation of Per1 1 0.05 0 0.09
110 INT147673 SRI Positive_regulation of Per1 1 0.03 0 0.09
111 INT253571 Positive_regulation of Binding of Lpl and Sp1 1 0.17 0.42 0.09
112 INT253579 Negative_regulation of Binding of Lpl and Sp1 1 0.15 0.42 0.09
113 INT147591 Binding of MAG and Muc1 1 0.46 0.83 0.09
114 INT313509 Binding of ALOX5 and SP1 1 0.07 1.51 0.08
115 INT321597 Binding of MUC1 and MIB1 1 0.19 0.98 0.08
116 INT287880 Binding of CREB1 and EP300 1 0.01 0 0.08
117 INT191758 ROS1 Positive_regulation of TFAP2A 1 0.01 0.54 0.08
118 INT147674 Binding of GRP and Per1 1 0.04 0 0.08
119 INT269569 MAPKAP1 Positive_regulation of PER1 1 0.01 0 0.08
120 INT269566 MAPKAP1 Positive_regulation of Localization of PER1 1 0.01 0 0.08
121 INT267592 IL6 Positive_regulation of Localization of MUC1 1 0.00 1.24 0.07
122 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07
123 INT253577 Csnk2a2 Positive_regulation of Phosphorylation of Sp1 1 0.17 0.37 0.06
124 INT118417 Gata1 Regulation of Gene_expression of Serpinb9g 1 0.17 0.12 0.06
125 INT332897 Ppara Regulation of Transcription of Clock 1 0.24 0.31 0.06
126 INT262214 Binding of Msx2 and Nr1i2 1 0.19 0.55 0.06
127 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
128 INT221368 EGFR Regulation of Gene_expression of MUC1 1 0.05 3.82 0.06
129 INT267593 IL8 Positive_regulation of Localization of MUC1 1 0.00 1.06 0.06
130 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06
131 INT206675 Adcyap1 Positive_regulation of Gene_expression of Per1 1 0.05 0 0.05
132 INT332900 Ppara Regulation of Clock 1 0.21 0 0.05
133 INT284449 Il11 Positive_regulation of TCF4 1 0.00 0.42 0.05
134 INT344747 ABAT Positive_regulation of Gene_expression of MUC1 1 0.04 0.6 0.05
135 INT213608 Binding of PER2 and CLOCK 1 0.22 0.65 0.04
136 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
137 INT213607 Binding of CSNK1D and CLOCK 1 0.27 0.65 0.04
138 INT295718 Binding of PTGER2 and Positive_regulation of Positive_regulation of SP1 1 0.02 0.58 0.04
139 INT176326 IL2 Positive_regulation of Gene_expression of MUC1 1 0.08 0.71 0.04
140 INT225569 Binding of Ncoa6 and Ep300 1 0.18 0.63 0.04
141 INT332889 Clock Regulation of Ppara 1 0.12 0 0.04
142 INT332886 Binding of Clock and Ppara 1 0.32 0 0.04
143 INT334867 Binding of C4b and Sox10 1 0.04 0 0.03
144 INT334872 Positive_regulation of Binding of C4b and Sox10 1 0.04 0 0.03
145 INT334864 Positive_regulation of Binding of Nfatc1 and Sox10 1 0.04 0 0.03
146 INT334873 Binding of Nfatc1 and Sox10 1 0.02 0 0.03
147 INT314052 Binding of VEGFA and Sp1 1 0.02 1.25 0.03
148 INT253566 Sp1 Positive_regulation of Lpl 1 0.18 0 0.03
149 INT236720 Binding of Ctnnd2 and Tcf4 3 0.24 2.8 0
150 INT347577 Binding of MUC1 and MUC16 1 0.25 0.42 0
151 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
152 INT262169 Binding of Foxa2 and Nr1i2 1 0.17 0.33 0
153 INT225562 Binding of Srcs4 and Ep300 1 0.02 0 0
154 INT262183 Foxa2 Positive_regulation of Gene_expression of Hmgcs2 1 0.10 0.22 0
155 INT247660 PER1 Positive_regulation of TNNI3 1 0.01 0.35 0
156 INT213606 CLOCK Regulation of Gene_expression of PROK2 1 0.20 0.3 0
157 INT290813 Arntl Positive_regulation of Gene_expression of Clock 1 0.21 0 0
158 INT197810 Binding of MEN1 and MUC1 1 0.06 0.47 0
159 INT332887 Clock Positive_regulation of Ppara 1 0.71 0 0
160 INT262172 Nr1i2 Regulation of Msx2 1 0.12 0.53 0
161 INT287875 EP300 Negative_regulation of HDAC9 1 0.04 0.51 0
162 INT336537 Binding of Clock and Cry2 1 0.32 0 0
163 INT349987 Per1 Positive_regulation of Gene_expression of Diap1 1 0.08 0 0
164 INT339693 HMGCR Positive_regulation of SREBF2 1 0.05 0.54 0
165 INT326727 Sox10 Regulation of Regulation of Itk 1 0.02 0.06 0
166 INT326898 Positive_regulation of Tcf4 Regulation of PLD2 1 0.26 0.33 0
167 INT180028 Gopc Regulation of Bhlhe41 1 0.12 1.17 0
168 INT245820 Binding of Sp1 and Tfap2a 1 0.03 0.64 0
169 INT267257 BCL11B Regulation of Transcription of BMI1 1 0.28 0.74 0
170 INT336530 Positive_regulation of Binding of Clock and Arntl2 1 0.47 0 0
171 INT326893 Binding of Tcf4 and Wnt3a 1 0.13 0 0
172 INT172604 Binding of EP300 and TP53 1 0.00 0 0
173 INT337408 Binding of TCF4 and KLF4 1 0.09 0 0
174 INT326899 Tcf4 Positive_regulation of PLD2 1 0.28 0.49 0
175 INT332884 Clock Regulation of Gene_expression of Ppara 1 0.63 0.06 0
176 INT243107 Binding of Src and Ep300 1 0.06 0.17 0
177 INT132208 MUC1 Regulation of KRT7 1 0.02 0.18 0
178 INT326895 Binding of PLD2 and Tcf4 1 0.27 0.39 0
179 INT269954 Sox17 Regulation of Gene_expression of Foxa2 1 0.43 0 0
180 INT172606 EP300 Positive_regulation of CREBBP 1 0.00 0.07 0
181 INT282880 MMP14 Regulation of MUC1 1 0.02 0.17 0
182 INT280830 Binding of Avp and Usf2 1 0.02 0.53 0
183 INT269933 Foxa2 Regulation of Gene_expression of Foxj1 1 0.27 0 0
184 INT267258 Binding of TP53 and BCL11B 1 0.09 0.42 0
185 INT326900 Tcf4 Regulation of PLD2 1 0.15 0.33 0
186 INT225619 Binding of TARBP2 and Ep300 1 0.02 0 0
187 INT225481 Binding of Med1 and Acp5 1 0.16 0 0
188 INT300164 Npas2 Positive_regulation of Transcription of Per1 1 0.13 0.23 0
189 INT175729 Binding of ARNTL and PER1 1 0.19 0.07 0
190 INT280812 Usf2 Positive_regulation of Gene_expression of Avp 1 0.03 0.52 0
191 INT296999 Binding of EPS15 and TFAP2A 1 0.06 0.2 0
192 INT215344 Binding of Sp1 and Vdac1 1 0.02 0.1 0
193 INT282881 MUC1 Positive_regulation of Gene_expression of MMP14 1 0.04 0.17 0
194 INT175730 Binding of CLOCK and ARMC9 1 0.02 0.06 0
195 INT245828 Binding of VEGFA and Tfap2a 1 0.01 0.64 0
196 INT326728 Sox10 Regulation of Twist2 1 0.45 0.05 0
197 INT332883 Binding of Clock and Tcf12 1 0.02 0 0
198 INT337891 Per1 Positive_regulation of Nr2f2 1 0.08 0.16 0
199 INT161358 Binding of SOX10 and Nes 1 0.02 0.11 0
200 INT304168 Binding of Gata1 and Sfpi1 1 0.08 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II core promoter proximal region sequence-specific DNA binding. They are ordered first by their pain relevance and then by number of times they were reported in RNA polymerase II core promoter proximal region sequence-specific DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19
2 INT127435 Gene_expression of Per1 89 0.77 13.94 22.31
3 INT41558 Localization of Sp1 9 0.48 0.56 14.9
4 INT24082 Negative_regulation of Sp1 13 0.40 1.19 13.11
5 INT128054 Gene_expression of Per1 15 0.61 2.12 11.84
6 INT149818 Gene_expression of Clock 81 0.70 14.15 10.04
7 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
8 INT49802 Localization of MUC1 75 0.81 44.74 8.87
9 INT130117 Regulation of Per1 26 0.53 3.25 7.63
10 INT17041 Gene_expression of PER1 24 0.66 5.31 7.12
11 INT159518 Gene_expression of Clock 4 0.35 2.34 6.91
12 INT48555 Binding of SP1 30 0.46 11.38 6.53
13 INT170385 Regulation of Clock 29 0.49 4.95 6.39
14 INT41604 Negative_regulation of Localization of Sp1 2 0.30 0.32 5.86
15 INT128045 Positive_regulation of Per1 29 0.69 5.32 5.5
16 INT128324 Regulation of Gene_expression of Per1 11 0.61 1.95 5.22
17 INT49805 Positive_regulation of MUC1 56 0.70 44.5 4.56
18 INT138216 Negative_regulation of PER1 13 0.37 9.66 4.55
19 INT2213 Regulation of EP300 10 0.54 4.72 4.5
20 INT127434 Negative_regulation of Gene_expression of Per1 12 0.58 2.58 4.2
21 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
22 INT123411 Gene_expression of Sp1 15 0.69 4.2 3.79
23 INT84809 Positive_regulation of Gene_expression of MUC1 39 0.70 36.42 3.75
24 INT130119 Transcription of Per1 28 0.67 1.92 3.56
25 INT41559 Positive_regulation of Sp1 7 0.45 2.65 3.24
26 INT123409 Binding of Sp1 20 0.39 3.18 3.15
27 INT161812 Positive_regulation of PER1 17 0.56 5.64 2.93
28 INT103607 Binding of Sp1 7 0.42 1.26 2.92
29 INT93213 Phosphorylation of Sp1 5 0.67 0.93 2.84
30 INT351263 Binding of CLOCK 1 0.18 0.46 2.71
31 INT185407 Binding of PER1 13 0.42 9.32 2.6
32 INT24902 Gene_expression of SP1 17 0.71 8.11 2.58
33 INT23998 Positive_regulation of Sp1 4 0.40 0.51 2.56
34 INT196971 Positive_regulation of Gene_expression of Per1 8 0.69 1.23 2.44
35 INT103609 Transcription of Sp1 1 0.11 0.97 2.42
36 INT9473 Binding of MUC1 66 0.48 46.77 2.36
37 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29
38 INT173005 Transcription of MUC1 11 0.63 10.15 2.24
39 INT103608 Negative_regulation of Binding of Sp1 4 0.35 0.69 2.1
40 INT49803 Negative_regulation of MUC1 37 0.58 26.37 2.06
41 INT41495 Regulation of Sp1 7 0.42 2.96 2.05
42 INT41557 Gene_expression of Sp1 5 0.68 1.17 2.04
43 INT26123 Regulation of Ep300 6 0.23 1.22 2.03
44 INT171514 Binding of EP300 13 0.32 4.32 2.01
45 INT26124 Negative_regulation of Ep300 5 0.37 1.25 1.94
46 INT128058 Regulation of PER1 6 0.43 1.82 1.89
47 INT170387 Transcription of Clock 11 0.63 1.78 1.83
48 INT128053 Positive_regulation of Per1 5 0.35 0.54 1.83
49 INT280889 Gene_expression of Sox10 19 0.72 3.45 1.78
50 INT24906 Negative_regulation of SP1 8 0.40 4.48 1.77
51 INT172622 Localization of EP300 8 0.65 2.56 1.72
52 INT128060 Regulation of Gene_expression of PER1 4 0.52 2.41 1.72
53 INT139254 Negative_regulation of Per1 12 0.56 3.17 1.62
54 INT118412 Gene_expression of Gata1 5 0.62 0.83 1.6
55 INT41605 Positive_regulation of Localization of Sp1 1 0.05 0 1.58
56 INT118413 Positive_regulation of Gene_expression of Gata1 3 0.40 0.68 1.56
57 INT132163 Positive_regulation of Localization of MUC1 9 0.19 8.96 1.54
58 INT188683 Binding of Per1 10 0.37 0.9 1.47
59 INT149815 Positive_regulation of Gene_expression of Clock 7 0.46 0.87 1.45
60 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
61 INT128057 Positive_regulation of Gene_expression of PER1 7 0.59 1.21 1.39
62 INT248976 Positive_regulation of Clock 8 0.48 0.15 1.38
63 INT123414 Transcription of Sp1 5 0.48 2.2 1.38
64 INT94692 Positive_regulation of Gene_expression of Sp1 3 0.17 0.39 1.28
65 INT24000 Regulation of Sp1 2 0.22 1.25 1.27
66 INT48554 Positive_regulation of SP1 12 0.49 3.64 1.2
67 INT70821 Positive_regulation of Ep300 4 0.25 1.47 1.2
68 INT49804 Negative_regulation of Localization of MUC1 7 0.59 5.84 1.19
69 INT128052 Positive_regulation of Gene_expression of Per1 1 0.05 0 1.14
70 INT93216 Negative_regulation of Phosphorylation of Sp1 2 0.14 0.4 1.13
71 INT160319 Negative_regulation of Gene_expression of Per1 1 0.41 0 1.09
72 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
73 INT217879 Protein_catabolism of Per1 2 0.54 0.09 1.03
74 INT133842 Binding of SOX10 3 0.38 5.79 1.02
75 INT206672 Positive_regulation of Transcription of Per1 8 0.55 0.61 1
76 INT167650 Binding of Ep300 1 0.09 0.14 1
77 INT147665 Positive_regulation of Positive_regulation of Per1 2 0.49 0.57 0.99
78 INT123408 Positive_regulation of Gene_expression of Sp1 2 0.62 0.9 0.96
79 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
80 INT123407 Negative_regulation of Binding of Sp1 6 0.47 0.72 0.93
81 INT200272 Localization of Sp1 3 0.57 0.06 0.93
82 INT351266 Regulation of Binding of CLOCK 1 0.21 0 0.92
83 INT243533 Positive_regulation of SOX10 1 0.35 3.93 0.92
84 INT351261 Regulation of Binding of PER1 1 0.40 0 0.91
85 INT196974 Regulation of Regulation of Per1 2 0.34 0.52 0.87
86 INT175747 Regulation of CLOCK 4 0.21 0.06 0.84
87 INT206670 Localization of Per1 4 0.75 0.96 0.83
88 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
89 INT123410 Negative_regulation of Gene_expression of Sp1 3 0.38 1.01 0.82
90 INT89290 Regulation of MUC1 19 0.45 10.4 0.81
91 INT149817 Gene_expression of Bhlhe41 2 0.43 2.47 0.81
92 INT133841 Gene_expression of SOX10 18 0.67 9.96 0.8
93 INT173003 Negative_regulation of Gene_expression of MUC1 15 0.57 10.27 0.79
94 INT282916 Positive_regulation of Transcription of MUC1 2 0.45 0.47 0.79
95 INT157238 Transcription of PER1 3 0.50 0.21 0.74
96 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
97 INT190968 Regulation of Per1 1 0.14 0 0.74
98 INT248971 Binding of Clock 8 0.34 1.12 0.73
99 INT74097 Gene_expression of Ep300 6 0.52 1.89 0.73
100 INT144995 Positive_regulation of Gata1 1 0.37 0.14 0.71
101 INT149819 Regulation of Gene_expression of Bhlhe41 1 0.29 0 0.7
102 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
103 INT121606 Positive_regulation of Usf2 1 0.26 0.1 0.69
104 INT149804 Regulation of Bhlhe41 1 0.29 0 0.69
105 INT132164 Gene_expression of Muc1 4 0.71 4.15 0.67
106 INT98967 Localization of SP1 2 0.60 0.15 0.66
107 INT24905 Negative_regulation of Gene_expression of SP1 4 0.39 2.05 0.65
108 INT248978 Localization of Clock 1 0.70 0.3 0.61
109 INT248974 Negative_regulation of Transcription of Per1 2 0.48 0.33 0.6
110 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
111 INT80300 Gene_expression of TFAP2A 5 0.54 2.76 0.59
112 INT126899 Regulation of SP1 5 0.43 2.53 0.57
113 INT148768 Gene_expression of Usf2 1 0.57 0.39 0.57
114 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
115 INT267269 Gene_expression of BCL11B 62 0.78 48.75 0.55
116 INT89334 Negative_regulation of Binding of SP1 2 0.47 1.05 0.5
117 INT343798 Negative_regulation of Transcription of MUC1 1 0.39 0.37 0.5
118 INT243538 Regulation of SOX10 1 0.31 3.27 0.48
119 INT230623 Negative_regulation of SOX10 2 0.36 0.46 0.46
120 INT204005 Negative_regulation of Gene_expression of Clock 3 0.39 0.58 0.45
121 INT173022 Regulation of Gene_expression of MUC1 9 0.60 7.59 0.44
122 INT126896 Positive_regulation of Protein_catabolism of SP1 1 0.13 0.99 0.44
123 INT128059 Regulation of Regulation of PER1 1 0.20 0 0.44
124 INT304572 Regulation of Binding of Clock 1 0.30 0.29 0.43
125 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39
126 INT196973 Regulation of Gene_expression of Clock 12 0.38 3.58 0.38
127 INT80302 Binding of TFAP2A 7 0.39 1.67 0.38
128 INT126895 Protein_catabolism of SP1 3 0.96 3.59 0.38
129 INT234421 Binding of TCF4 13 0.18 2.3 0.37
130 INT98963 Positive_regulation of Binding of SP1 1 0.43 0 0.37
131 INT166959 Positive_regulation of Positive_regulation of SP1 3 0.46 2.23 0.35
132 INT106402 Positive_regulation of TFAP2A 2 0.13 0.35 0.35
133 INT187587 Binding of Ep300 11 0.35 2.37 0.34
134 INT173635 Negative_regulation of TFAP2A 3 0.34 2.93 0.33
135 INT136460 Negative_regulation of Sp1 2 0.30 0.99 0.3
136 INT148980 Negative_regulation of Gene_expression of PER1 1 0.49 0.08 0.3
137 INT98598 Negative_regulation of Positive_regulation of TCF4 1 0.22 0.57 0.28
138 INT98596 Positive_regulation of TCF4 3 0.26 1.13 0.27
139 INT93215 Positive_regulation of Phosphorylation of Sp1 1 0.11 0.09 0.27
140 INT148769 Regulation of Usf2 1 0.43 0.24 0.27
141 INT292207 Negative_regulation of Gene_expression of TFAP2A 1 0.05 1.2 0.27
142 INT157244 Localization of PER1 8 0.50 2.4 0.26
143 INT114369 Positive_regulation of Tcf4 6 0.40 2.7 0.25
144 INT253556 Phosphorylation of Sp1 6 0.44 2.93 0.24
145 INT325492 Regulation of Ep300 1 0.04 0.29 0.24
146 INT147586 Positive_regulation of Gene_expression of Muc1 1 0.43 2.54 0.22
147 INT114372 Negative_regulation of Tcf4 2 0.25 0.7 0.2
148 INT348361 Localization of Muc1 1 0.27 0.58 0.2
149 INT136457 Negative_regulation of Negative_regulation of Sp1 1 0.30 0.65 0.2
150 INT253542 Positive_regulation of Phosphorylation of Sp1 1 0.27 1.16 0.2
151 INT212787 Negative_regulation of Binding of EP300 1 0.13 0.53 0.2
152 INT256666 Regulation of Gene_expression of EP300 1 0.14 0.07 0.2
153 INT256661 Regulation of Positive_regulation of EP300 1 0.23 0.07 0.2
154 INT130118 Regulation of Transcription of Per1 2 0.43 0.11 0.19
155 INT269637 Positive_regulation of Phosphorylation of PER1 1 0.04 0 0.19
156 INT203497 Gene_expression of Pou4f2 1 0.63 1.05 0.19
157 INT325490 Positive_regulation of Ep300 1 0.03 0.22 0.19
158 INT197429 Gene_expression of TCF4 6 0.33 3.8 0.18
159 INT162939 Binding of Tfap2a 1 0.26 0.34 0.17
160 INT162940 Negative_regulation of Tfap2a 1 0.32 0.34 0.17
161 INT114370 Negative_regulation of Positive_regulation of Tcf4 1 0.10 0.63 0.17
162 INT255393 Regulation of SREBF2 1 0.27 0.78 0.17
163 INT162941 Negative_regulation of Binding of Tfap2a 1 0.32 0.34 0.17
164 INT210249 Gene_expression of Tcf4 14 0.66 4.32 0.16
165 INT178673 Positive_regulation of Gene_expression of SP1 1 0.08 0.14 0.16
166 INT243532 Positive_regulation of Gene_expression of SOX10 1 0.55 0.86 0.15
167 INT243529 Regulation of Gene_expression of SOX10 1 0.31 1.27 0.15
168 INT298653 Positive_regulation of Binding of EP300 1 0.11 0.8 0.15
169 INT176329 Protein_catabolism of MUC1 4 0.72 2.14 0.14
170 INT305524 Positive_regulation of Sox10 2 0.39 0.36 0.14
171 INT220570 Transcription of Gata1 2 0.05 0.91 0.14
172 INT290777 Phosphorylation of Clock 1 0.42 0.41 0.14
173 INT255398 Regulation of Localization of SREBF2 1 0.45 0.81 0.13
174 INT280888 Localization of Sox10 1 0.69 0.06 0.13
175 INT147589 Binding of Muc1 1 0.41 2.48 0.13
176 INT206779 Regulation of Positive_regulation of PER1 1 0.03 0.18 0.13
177 INT149063 Regulation of BCL11B 1 0.11 0.06 0.12
178 INT305529 Negative_regulation of Positive_regulation of Sox10 1 0.33 0.36 0.11
179 INT255391 Localization of SREBF2 1 0.74 0.8 0.11
180 INT236704 Binding of Tcf4 3 0.28 3.3 0.1
181 INT326846 Negative_regulation of Binding of Tcf4 1 0.25 0.26 0.1
182 INT173632 Transcription of SP1 7 0.41 1.42 0.09
183 INT290793 Negative_regulation of Clock 6 0.39 1.48 0.09
184 INT234413 Transcription of TCF4 3 0.34 1 0.09
185 INT322523 Regulation of Transcription of SP1 1 0.11 0.15 0.09
186 INT287943 Negative_regulation of Transcription of TCF4 1 0.15 0 0.09
187 INT176328 Positive_regulation of Protein_catabolism of MUC1 1 0.41 0.86 0.09
188 INT287918 Negative_regulation of Binding of TCF4 1 0.15 0 0.09
189 INT217893 Phosphorylation of Per1 1 0.70 0 0.09
190 INT269661 Phosphorylation of PER1 1 0.07 0 0.09
191 INT255389 Gene_expression of SREBF2 3 0.77 1.67 0.08
192 INT280891 Transcription of Sox10 2 0.64 0.28 0.08
193 INT282927 Regulation of Localization of MUC1 1 0.26 0.92 0.07
194 INT175751 Localization of CLOCK 1 0.40 0 0.07
195 INT296212 Negative_regulation of CLOCK 1 0.04 0.24 0.07
196 INT129204 Positive_regulation of Positive_regulation of MUC1 2 0.09 1.01 0.06
197 INT97754 Regulation of Gene_expression of TFAP2A 1 0.36 0.13 0.06
198 INT203988 Localization of Per1 1 0.68 0.14 0.06
199 INT147587 Negative_regulation of Muc1 1 0.50 0.88 0.06
200 INT217881 Positive_regulation of Phosphorylation of Per1 1 0.40 0 0.05
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