GO:0000979

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Name RNA polymerase II core promoter sequence-specific DNA binding
Categary Function
Go Slim No
Go Link GO:0000979
Unique Molecular Interactions 248
Total Molecular Interactions 325
Total Single Events 2299
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II core promoter sequence-specific DNA binding. They are ordered first by their pain relevance and then by number of times they were reported for RNA polymerase II core promoter sequence-specific DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
2 INT220623 Binding of Stat1 and Bace1 11 0.25 10.33 3.81
3 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
4 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
5 INT200323 Binding of Oprm1 and Sp3 1 0.39 0 0.99
6 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
7 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
8 INT139330 Binding of SGCG and Stat1 1 0.37 0.75 0.94
9 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
10 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92
11 INT77254 Binding of gr and Sp1 1 0.04 0.4 0.9
12 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88
13 INT167947 Binding of STAT1 and Oprm1 1 0.00 0 0.86
14 INT167944 Binding of Oprm1 and Stat5a 1 0.00 0 0.85
15 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
16 INT207542 Sp1 Regulation of Oprm1 1 0.15 0.06 0.7
17 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
18 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
19 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
20 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
21 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
22 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
23 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
24 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
25 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
26 INT92026 Egr1 Positive_regulation of Fos 1 0.50 0.61 0.67
27 INT207547 Sp1 Regulation of Qsox1 1 0.05 0.06 0.67
28 INT126614 Ppyr1 Negative_regulation of Phosphorylation of Stat5a 1 0.27 0.1 0.64
29 INT223155 Binding of Mapk14 and Stat4 1 0.36 0.84 0.63
30 INT123416 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.60 0 0.63
31 INT126615 Binding of Oprd1 and Stat5a 1 0.28 0.07 0.61
32 INT184100 Il6 Positive_regulation of Stat1 1 0.16 0.68 0.58
33 INT200348 Sp3 Negative_regulation of Gene_expression of Oprm1 1 0.48 0.4 0.55
34 INT261478 Positive_regulation of Ephb1 Regulation of Gene_expression of Egr1 1 0.10 0.23 0.55
35 INT184130 Epo Positive_regulation of Stat5a 1 0.31 0.26 0.52
36 INT184096 Il7 Positive_regulation of Stat5a 1 0.07 0.26 0.51
37 INT121821 Binding of STAT1 and Olr1583 1 0.00 0.21 0.51
38 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51
39 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
40 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
41 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
42 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
43 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
44 INT138927 Ifng Positive_regulation of Gene_expression of Stat1 1 0.29 0.7 0.49
45 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
46 INT167946 Binding of SRC and Stat5b 1 0.28 0 0.38
47 INT200313 Sp3 Regulation of Oprm1 1 0.10 0.07 0.38
48 INT200301 Sp3 Regulation of Rorb 1 0.00 0.07 0.38
49 INT130930 Egr1 Negative_regulation of Positive_regulation of Thbs1 1 0.58 0.64 0.38
50 INT167558 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.03 0.07 0.36
51 INT123495 Negative_regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
52 INT123493 Regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
53 INT90722 Nr4a1 Positive_regulation of Egr1 1 0.20 0.48 0.35
54 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35
55 INT200333 Binding of Rest and Sp1 1 0.24 0.07 0.35
56 INT90724 Egr3 Positive_regulation of Egr1 1 0.33 0.48 0.35
57 INT200316 Sp1 Regulation of Gene_expression of Rest 1 0.31 0 0.35
58 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
59 INT315400 IFNA1 Positive_regulation of Phosphorylation of Stat1 1 0.02 0.4 0.33
60 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33
61 INT184110 Jak1 Positive_regulation of Stat1 1 0.32 0.3 0.33
62 INT253576 Binding of Lpl and Sp3 1 0.22 0.85 0.32
63 INT126097 Ddc Positive_regulation of Egr1 1 0.08 0 0.32
64 INT200351 Sp1 Positive_regulation of Gene_expression of Rest 1 0.34 0.07 0.3
65 INT315392 IFNA1 Positive_regulation of Stat1 1 0.02 0.4 0.3
66 INT74334 Penk Regulation of Transcription of Egr1 1 0.40 0.25 0.29
67 INT180570 Binding of HEYL and Positive_regulation of DMD 1 0.00 1.08 0.28
68 INT74336 Crh Regulation of Transcription of Egr1 1 0.49 0.24 0.28
69 INT147356 Egr1 Positive_regulation of Gene_expression of Btg1 1 0.14 1.56 0.28
70 INT180564 HEYL Regulation of Regulation of DMD 1 0.00 0.88 0.28
71 INT147358 Egr1 Positive_regulation of Gene_expression of Gdf15 1 0.14 1.56 0.28
72 INT58182 Fos Regulation of Egr1 1 0.49 0.09 0.27
73 INT147359 Positive_regulation of Pik3cd Positive_regulation of Egr1 1 0.09 1.51 0.27
74 INT332246 Ros1 Positive_regulation of Stat1 1 0.02 0.46 0.27
75 INT130931 Sis Negative_regulation of Egr1 1 0.01 0.52 0.27
76 INT58176 Junb Regulation of Egr1 1 0.46 0.09 0.27
77 INT147360 Pik3cd Positive_regulation of Egr1 1 0.12 1.51 0.27
78 INT169837 Sp1 Positive_regulation of Gene_expression of Kcnq3 1 0.04 0.08 0.26
79 INT169836 Sp1 Positive_regulation of Gene_expression of Kcnq2 1 0.05 0.08 0.26
80 INT260739 Mapk14 Regulation of Positive_regulation of Sp1 1 0.01 1.06 0.25
81 INT200309 Positive_regulation of Binding of Rest and Sp3 1 0.41 0.88 0.24
82 INT130060 PPARG Positive_regulation of Positive_regulation of Egr1 1 0.22 0.46 0.24
83 INT253563 Csnk2a2 Regulation of Phosphorylation of Stat1 1 0.16 0.58 0.24
84 INT163760 Ifng Positive_regulation of Phosphorylation of Stat1 1 0.12 0.08 0.23
85 INT138929 Ifng Positive_regulation of Stat1 1 0.29 0.28 0.23
86 INT138926 Regulation of Ifng Positive_regulation of Stat1 1 0.17 0.28 0.23
87 INT138931 Ifng Positive_regulation of Positive_regulation of Stat1 1 0.31 0.28 0.23
88 INT186351 Binding of Gast and Stat1 3 0.16 2.77 0.22
89 INT184162 Egr1 Positive_regulation of Transcription of Ptges2 1 0.08 0.42 0.22
90 INT184160 Binding of Egr1 and Ptges2 1 0.07 0.4 0.22
91 INT253568 Negative_regulation of Binding of Lpl and Sp3 1 0.19 0.37 0.22
92 INT94338 IFNG Positive_regulation of Phosphorylation of Stat1 1 0.01 0.26 0.21
93 INT94339 IFNG Positive_regulation of Localization of Stat1 1 0.01 0.26 0.21
94 INT271853 Ngf Positive_regulation of Gene_expression of Egr1 1 0.53 1.36 0.21
95 INT259817 Ltp Positive_regulation of Egr1 1 0.03 0.28 0.2
96 INT259812 Gtf3a Regulation of Egr1 1 0.01 0.58 0.19
97 INT184159 Egr1 Positive_regulation of Ptges2 1 0.07 0.34 0.19
98 INT136462 Negative_regulation of Ptgs1 Negative_regulation of Gene_expression of Sp1 1 0.01 0.65 0.19
99 INT58178 Gtf3a Positive_regulation of Egr1 1 0.07 0.09 0.19
100 INT184161 Negative_regulation of Egr1 Positive_regulation of Ptges2 1 0.07 0.34 0.19
101 INT259814 Binding of Arc and Egr1 1 0.34 0.55 0.19
102 INT259813 Binding of Egr1 and Arc 1 0.32 0.55 0.19
103 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19
104 INT58181 Gtf3a Positive_regulation of Gene_expression of Egr1 1 0.07 0.1 0.19
105 INT139015 STAT1 Negative_regulation of Gene_expression of PTGS2 1 0.01 0.36 0.19
106 INT332251 Il13 Positive_regulation of Stat1 1 0.14 1.4 0.18
107 INT140095 Stat1 Positive_regulation of Positive_regulation of Ifng 1 0.52 0.42 0.18
108 INT317895 Fos Regulation of Transcription of Egr1 1 0.41 1.03 0.17
109 INT317897 Egr1 Regulation of Transcription of Fosb 1 0.34 1.08 0.17
110 INT314078 Peo1 Negative_regulation of Stat1 1 0.31 1.23 0.17
111 INT317892 Egr1 Regulation of Transcription of Fos 1 0.41 1.03 0.17
112 INT180562 Binding of CYP27A1 and HEYL 1 0.02 0.29 0.16
113 INT190634 Binding of Lmo2 and Maz 1 0.14 0.59 0.16
114 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15
115 INT343848 Positive_regulation of TLR4 Positive_regulation of STAT1 1 0.17 0.16 0.15
116 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15
117 INT295273 STAT1 Regulation of Transcription of Hp 1 0.00 0.63 0.15
118 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15
119 INT314069 Gopc Negative_regulation of Stat1 1 0.14 0.95 0.15
120 INT168806 Tlr4 Positive_regulation of Gene_expression of Egr1 1 0.18 0.3 0.15
121 INT343835 TLR4 Positive_regulation of STAT1 1 0.17 0.11 0.15
122 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15
123 INT295272 STAT1 Regulation of Hp 1 0.00 0.63 0.14
124 INT249598 Stat1 Positive_regulation of Gene_expression of Cd40 1 0.41 0.46 0.14
125 INT332243 Pdgfa Positive_regulation of Stat1 1 0.06 0.52 0.14
126 INT253564 Binding of Lpl and Sp1 1 0.13 0.9 0.14
127 INT343861 Binding of IFN1@ and STAT1 1 0.00 0.13 0.14
128 INT186372 Binding of Irf1 and Stat1 1 0.04 2.06 0.14
129 INT295271 STAT1 Regulation of Gbp2 1 0.00 0.63 0.14
130 INT247267 Binding of Egr1 and Mecp2 1 0.12 0.18 0.13
131 INT184129 Socs2 Negative_regulation of Stat5a 1 0.22 0.05 0.13
132 INT223535 Binding of HAND1 and Pax6 1 0.33 0.92 0.13
133 INT200328 Sp3 Positive_regulation of Gene_expression of Oprm1 1 0.38 0 0.13
134 INT311905 Binding of Runx2 and Smad1 1 0.12 0.46 0.13
135 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13
136 INT223526 Binding of Pax6 and Tcf3 1 0.33 0.92 0.13
137 INT311912 Gene_expression of Smad1 Positive_regulation of Gene_expression of Mmp13 1 0.08 0.51 0.12
138 INT200315 Binding of Sp1 and Sp3 1 0.29 0 0.12
139 INT180567 HEYL Regulation of Positive_regulation of IBSP 1 0.01 0.18 0.12
140 INT68802 Sp1 Regulation of Gene_expression of Pebp1 1 0.24 0 0.12
141 INT317891 Binding of Akt1 and Mtf1 1 0.21 1.04 0.11
142 INT253572 Binding of Csnk2a2 and Sp1 1 0.17 0 0.11
143 INT317896 Binding of Mmp9 and Mtf1 1 0.36 1.04 0.11
144 INT317887 Binding of Mtf1 and Pik3r1 1 0.25 1.04 0.11
145 INT200320 Binding of Sp3 and Negative_regulation of Gene_expression of Oprm1 1 0.35 0.4 0.1
146 INT171163 Creb1 Regulation of Sp1 1 0.03 0.62 0.1
147 INT194822 Negative_regulation of MAPK1 Negative_regulation of Binding of Sp1 1 0.04 0.05 0.1
148 INT184089 Gh Positive_regulation of Stat5b 1 0.13 1.3 0.1
149 INT208300 IGIP Positive_regulation of Stat1 1 0.07 0.42 0.09
150 INT253571 Positive_regulation of Binding of Lpl and Sp1 1 0.17 0.42 0.09
151 INT315383 Adcyap1 Regulation of Stat1 1 0.10 0.07 0.09
152 INT253579 Negative_regulation of Binding of Lpl and Sp1 1 0.15 0.42 0.09
153 INT204902 Negative_regulation of Tlr4 Positive_regulation of Stat1 1 0.23 0.09 0.09
154 INT204879 Tlr4 Positive_regulation of Stat1 1 0.25 0.09 0.09
155 INT180561 HEYL Negative_regulation of IBSP 1 0.01 0.19 0.09
156 INT314075 Peo1 Regulation of Positive_regulation of Stat1 1 0.37 0.43 0.08
157 INT262939 PAX6 Regulation of CDH4 1 0.02 0.97 0.08
158 INT316793 Binding of HLA-DRB1 and Stat4 1 0.07 0.33 0.08
159 INT262937 PAX6 Regulation of CDH8 1 0.03 0.98 0.08
160 INT271284 Binding of IFNA1 and Stat1 1 0.07 0.7 0.08
161 INT314064 Gopc Negative_regulation of Positive_regulation of Stat1 1 0.12 0.57 0.08
162 INT191758 ROS1 Positive_regulation of TFAP2A 1 0.01 0.54 0.08
163 INT262944 PAX6 Regulation of CDH6 1 0.03 0.97 0.08
164 INT186369 Negative_regulation of Binding of Gast and Stat1 1 0.04 1.04 0.07
165 INT267016 Bdnf Positive_regulation of Egr1 1 0.12 0.09 0.07
166 INT204891 Tlr4 Negative_regulation of Stat1 1 0.10 0.09 0.07
167 INT186366 Binding of Stat1 and Stat6 1 0.12 1.04 0.07
168 INT253570 Binding of Csnk2a2 and Sp3 1 0.16 0.2 0.07
169 INT253577 Csnk2a2 Positive_regulation of Phosphorylation of Sp1 1 0.17 0.37 0.06
170 INT311910 Acvrl1 Positive_regulation of Phosphorylation of Smad1 1 0.12 0.24 0.06
171 INT60221 Agt Regulation of Gene_expression of Egr1 1 0.42 0 0.04
172 INT311904 Smad2 Positive_regulation of Gene_expression of Smad1 1 0.13 0.44 0.03
173 INT314067 Stat1 Regulation of Nos2 1 0.13 0.2 0.03
174 INT243636 Stat1 Positive_regulation of Gene_expression of Twist1 1 0.46 0.05 0.03
175 INT243766 Binding of Egr1 and Proc 1 0.01 0.2 0.03
176 INT319219 Bmpr2 Positive_regulation of Smad1 1 0.18 0.29 0.03
177 INT253574 Sp3 Positive_regulation of Lpl 1 0.22 0 0.03
178 INT314077 Peo1 Negative_regulation of Positive_regulation of Stat1 1 0.31 0.33 0.03
179 INT249597 Jak2 Positive_regulation of Phosphorylation of Stat1 1 0.20 0.13 0.03
180 INT314071 Stat1 Regulation of Cxcl10 1 0.26 0.2 0.03
181 INT180565 HEYL Positive_regulation of Negative_regulation of COL1A1 1 0.01 0 0.03
182 INT180571 HEYL Positive_regulation of Protein_catabolism of COL1A1 1 0.01 0 0.03
183 INT319217 Bmpr2 Positive_regulation of Gene_expression of Smad1 1 0.19 0.11 0.03
184 INT314052 Binding of VEGFA and Sp1 1 0.02 1.25 0.03
185 INT253566 Sp1 Positive_regulation of Lpl 1 0.18 0 0.03
186 INT280543 Binding of GAST and STAT1 1 0.05 0.58 0
187 INT353192 Stat5a Positive_regulation of Plxna3 1 0.01 0 0
188 INT262938 Binding of PAX6 and SIX3 1 0.13 0.9 0
189 INT332409 Egr1 Regulation of Hgf 1 0.26 0.14 0
190 INT240122 Nab2 Regulation of Egr1 1 0.09 0.59 0
191 INT332408 Binding of Egr1 and Hgf 1 0.35 0.14 0
192 INT243770 Egr1 Regulation of Nab2 1 0.28 0.09 0
193 INT245820 Binding of Sp1 and Tfap2a 1 0.03 0.64 0
194 INT177790 MTF1 Positive_regulation of NR2F1 1 0.10 0 0
195 INT271280 Stat1 Regulation of Mcl1 1 0.28 0.67 0
196 INT329746 ENG Positive_regulation of SMAD1 1 0.15 0.44 0
197 INT177788 NR4A1 Positive_regulation of MTF1 1 0.08 0 0
198 INT259811 Narp Positive_regulation of Gene_expression of Egr1 1 0.26 0.86 0
199 INT271281 Gene_expression of Stat1 Positive_regulation of Insr 1 0.19 0.51 0
200 INT301365 Stat1 Positive_regulation of Cdkn1a 1 0.03 0.38 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II core promoter sequence-specific DNA binding. They are ordered first by their pain relevance and then by number of times they were reported in RNA polymerase II core promoter sequence-specific DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
2 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
3 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
4 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95
5 INT41558 Localization of Sp1 9 0.48 0.56 14.9
6 INT57878 Positive_regulation of Gene_expression of Egr1 36 0.70 20.42 14.45
7 INT24082 Negative_regulation of Sp1 13 0.40 1.19 13.11
8 INT57876 Positive_regulation of Egr1 46 0.70 25.6 9.41
9 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
10 INT138922 Positive_regulation of Stat1 57 0.69 28.35 7.2
11 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
12 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
13 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38
14 INT163756 Phosphorylation of Stat1 45 0.82 14.51 6.11
15 INT41604 Negative_regulation of Localization of Sp1 2 0.30 0.32 5.86
16 INT138915 Gene_expression of Stat1 144 0.77 69.53 5.85
17 INT118870 Positive_regulation of STAT1 36 0.67 26.18 5.46
18 INT47704 Regulation of Egr1 17 0.60 2.43 5.18
19 INT47706 Negative_regulation of Positive_regulation of Egr1 9 0.41 6.11 5.1
20 INT51944 Positive_regulation of Transcription of Egr1 12 0.49 1.96 4.72
21 INT117936 Regulation of Gene_expression of Egr1 18 0.60 9.37 4.45
22 INT198736 Binding of Sp3 23 0.40 4.77 4.42
23 INT126608 Binding of Stat5a 7 0.48 0.46 4.38
24 INT223153 Binding of Stat4 5 0.34 7.98 4.28
25 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
26 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
27 INT123411 Gene_expression of Sp1 15 0.69 4.2 3.79
28 INT123502 Binding of Egr1 11 0.35 6.7 3.77
29 INT41559 Positive_regulation of Sp1 7 0.45 2.65 3.24
30 INT184060 Negative_regulation of Stat1 28 0.58 17.44 3.19
31 INT123409 Binding of Sp1 20 0.39 3.18 3.15
32 INT103607 Binding of Sp1 7 0.42 1.26 2.92
33 INT93213 Phosphorylation of Sp1 5 0.67 0.93 2.84
34 INT94327 Phosphorylation of Stat1 9 0.80 2.06 2.8
35 INT119839 Gene_expression of STAT1 17 0.75 8.36 2.7
36 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
37 INT23998 Positive_regulation of Sp1 4 0.40 0.51 2.56
38 INT126610 Phosphorylation of Stat5a 5 0.82 0.8 2.52
39 INT96640 Negative_regulation of Gene_expression of Egr1 13 0.43 7.22 2.48
40 INT103609 Transcription of Sp1 1 0.11 0.97 2.42
41 INT74262 Negative_regulation of Egr1 15 0.57 7.51 2.41
42 INT15243 Regulation of Egr1 19 0.61 7.6 2.13
43 INT103608 Negative_regulation of Binding of Sp1 4 0.35 0.69 2.1
44 INT80599 Regulation of Positive_regulation of Egr1 3 0.28 0.46 2.09
45 INT41495 Regulation of Sp1 7 0.42 2.96 2.05
46 INT41557 Gene_expression of Sp1 5 0.68 1.17 2.04
47 INT142461 Positive_regulation of Positive_regulation of Stat1 7 0.54 5.06 1.94
48 INT126609 Positive_regulation of Phosphorylation of Stat5a 1 0.69 0.26 1.79
49 INT57875 Positive_regulation of Positive_regulation of Egr1 6 0.49 2.74 1.75
50 INT119837 Positive_regulation of Gene_expression of STAT1 6 0.49 3.66 1.73
51 INT138917 Positive_regulation of Gene_expression of Stat1 63 0.69 36.76 1.71
52 INT186309 Binding of Stat1 18 0.48 5.31 1.58
53 INT140089 Positive_regulation of Stat1 5 0.68 3.42 1.58
54 INT41605 Positive_regulation of Localization of Sp1 1 0.05 0 1.58
55 INT57877 Negative_regulation of Positive_regulation of Egr1 4 0.42 1.63 1.57
56 INT186064 Phosphorylation of STAT1 19 0.59 7.14 1.48
57 INT136459 Gene_expression of Sp3 6 0.64 1.97 1.47
58 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
59 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
60 INT53003 Positive_regulation of Positive_regulation of Egr1 6 0.64 2.36 1.44
61 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
62 INT139326 Gene_expression of Stat1 6 0.76 2.49 1.41
63 INT116008 Binding of Gata3 2 0.34 1.37 1.41
64 INT121820 Binding of STAT1 9 0.46 2.54 1.4
65 INT123414 Transcription of Sp1 5 0.48 2.2 1.38
66 INT141344 Transcription of Egr1 11 0.70 5.59 1.34
67 INT94692 Positive_regulation of Gene_expression of Sp1 3 0.17 0.39 1.28
68 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
69 INT24000 Regulation of Sp1 2 0.22 1.25 1.27
70 INT126605 Negative_regulation of Binding of Stat5a 1 0.58 0.15 1.27
71 INT216380 Gene_expression of PAX6 49 0.78 15.63 1.22
72 INT180588 Gene_expression of HEYL 13 0.52 8.37 1.19
73 INT180580 Binding of HEYL 7 0.17 4.49 1.15
74 INT121814 Regulation of STAT1 3 0.43 0.83 1.15
75 INT93216 Negative_regulation of Phosphorylation of Sp1 2 0.14 0.4 1.13
76 INT178262 Transcription of Stat1 4 0.59 4.73 1.12
77 INT139325 Positive_regulation of Gene_expression of Stat1 3 0.68 1.18 1.1
78 INT163755 Positive_regulation of Phosphorylation of Stat1 4 0.60 1.87 1.09
79 INT139324 Positive_regulation of Phosphorylation of Stat1 3 0.44 1 1.09
80 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
81 INT123503 Positive_regulation of Binding of Egr1 3 0.13 2.34 1.04
82 INT123501 Negative_regulation of Binding of Egr1 2 0.12 2.04 0.99
83 INT139019 Negative_regulation of STAT1 10 0.57 5.04 0.97
84 INT51947 Regulation of Transcription of Egr1 2 0.59 0.15 0.96
85 INT123408 Positive_regulation of Gene_expression of Sp1 2 0.62 0.9 0.96
86 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
87 INT123407 Negative_regulation of Binding of Sp1 6 0.47 0.72 0.93
88 INT136458 Negative_regulation of Sp3 3 0.39 1.53 0.93
89 INT200272 Localization of Sp1 3 0.57 0.06 0.93
90 INT128424 Transcription of STAT1 5 0.37 3.28 0.9
91 INT199483 Transcription of Stat1 2 0.43 1.14 0.89
92 INT163758 Regulation of Stat1 17 0.54 5.23 0.87
93 INT184015 Positive_regulation of Stat5a 9 0.46 3.32 0.86
94 INT137572 Gene_expression of Maz 3 0.66 10.9 0.85
95 INT167938 Positive_regulation of Phosphorylation of Stat5b 1 0.33 0 0.85
96 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
97 INT123410 Negative_regulation of Gene_expression of Sp1 3 0.38 1.01 0.82
98 INT167942 Binding of Stat5b 1 0.26 0 0.82
99 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
100 INT174553 Localization of Stat1 17 0.80 6.62 0.73
101 INT116012 Regulation of Positive_regulation of Gata3 1 0.20 0.07 0.71
102 INT6050 Localization of Egr1 4 0.68 0.53 0.7
103 INT116006 Positive_regulation of Transcription of Gata3 1 0.21 0.07 0.7
104 INT116010 Positive_regulation of Binding of Gata3 1 0.31 0.07 0.7
105 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
106 INT174537 Positive_regulation of HEYL 7 0.39 3.07 0.68
107 INT141341 Binding of Egr1 5 0.48 2.65 0.67
108 INT128422 Positive_regulation of Positive_regulation of STAT1 5 0.35 4.24 0.67
109 INT102686 Phosphorylation of Egr1 3 0.59 2.57 0.64
110 INT202416 Negative_regulation of Gata3 2 0.32 1.17 0.64
111 INT178250 Positive_regulation of Transcription of Stat1 2 0.43 2.72 0.64
112 INT126606 Negative_regulation of Stat5a 1 0.43 0.08 0.64
113 INT278714 Regulation of Phosphorylation of STAT1 1 0.21 0.81 0.62
114 INT159942 Positive_regulation of Stat5a 3 0.41 0.95 0.61
115 INT126612 Negative_regulation of Phosphorylation of Stat5a 1 0.42 0.1 0.61
116 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
117 INT290660 Negative_regulation of Gene_expression of Gata3 1 0.25 1.52 0.6
118 INT80300 Gene_expression of TFAP2A 5 0.54 2.76 0.59
119 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
120 INT81061 Regulation of Negative_regulation of Egr1 1 0.22 0 0.53
121 INT138919 Regulation of Gene_expression of Stat1 4 0.60 4.58 0.49
122 INT180578 Regulation of HEYL 3 0.06 3.15 0.49
123 INT94328 Localization of Stat1 4 0.31 0.86 0.48
124 INT168801 Localization of Egr1 4 0.78 0.7 0.48
125 INT138914 Regulation of Positive_regulation of Stat1 3 0.45 1.02 0.48
126 INT200264 Localization of Sp3 1 0.62 0 0.47
127 INT253558 Negative_regulation of Binding of Sp3 1 0.39 1.09 0.46
128 INT141342 Negative_regulation of Transcription of Egr1 4 0.43 2.39 0.45
129 INT186279 Negative_regulation of Binding of Stat1 3 0.42 0.96 0.45
130 INT328807 Positive_regulation of Positive_regulation of Stat1 1 0.24 0.08 0.45
131 INT129429 Negative_regulation of Stat1 2 0.41 1.09 0.44
132 INT245262 Negative_regulation of Gene_expression of Stat1 9 0.42 2.87 0.42
133 INT167941 Phosphorylation of Stat5b 1 0.58 0 0.42
134 INT285501 Gene_expression of Smad1 6 0.42 3.09 0.41
135 INT137574 Positive_regulation of Gene_expression of Maz 2 0.42 4.67 0.41
136 INT243756 Regulation of Positive_regulation of Egr1 7 0.45 1.18 0.4
137 INT138910 Negative_regulation of Positive_regulation of Stat1 3 0.57 0.81 0.39
138 INT311882 Negative_regulation of Smad1 1 0.25 0.99 0.39
139 INT80302 Binding of TFAP2A 7 0.39 1.67 0.38
140 INT137573 Binding of Maz 2 0.31 3.78 0.38
141 INT328813 Negative_regulation of Phosphorylation of Stat1 1 0.21 0 0.37
142 INT106402 Positive_regulation of TFAP2A 2 0.13 0.35 0.35
143 INT200265 Regulation of Sp3 2 0.37 0.25 0.34
144 INT173635 Negative_regulation of TFAP2A 3 0.34 2.93 0.33
145 INT283698 Gene_expression of Sox11 1 0.68 4.6 0.33
146 INT188498 Negative_regulation of Transcription of Egr1 3 0.41 0.14 0.32
147 INT206142 Localization of STAT1 7 0.78 3.09 0.31
148 INT189833 Negative_regulation of Phosphorylation of Stat1 4 0.51 1.1 0.3
149 INT189834 Regulation of Phosphorylation of Stat1 3 0.36 0.72 0.3
150 INT121817 Positive_regulation of Binding of STAT1 2 0.67 0.49 0.3
151 INT136460 Negative_regulation of Sp1 2 0.30 0.99 0.3
152 INT122401 Binding of Stat1 1 0.07 0.81 0.28
153 INT200276 Positive_regulation of Sp3 1 0.42 0.17 0.28
154 INT93215 Positive_regulation of Phosphorylation of Sp1 1 0.11 0.09 0.27
155 INT292207 Negative_regulation of Gene_expression of TFAP2A 1 0.05 1.2 0.27
156 INT253556 Phosphorylation of Sp1 6 0.44 2.93 0.24
157 INT200251 Phosphorylation of Sp3 2 0.67 0.42 0.24
158 INT141343 Positive_regulation of Transcription of Egr1 1 0.47 1.43 0.24
159 INT190599 Positive_regulation of Maz 1 0.20 1.05 0.24
160 INT94329 Positive_regulation of Localization of Stat1 1 0.02 0.26 0.22
161 INT346813 Positive_regulation of Regulation of Egr1 1 0.49 0.27 0.21
162 INT314061 Regulation of Negative_regulation of Stat1 1 0.23 0.79 0.21
163 INT136457 Negative_regulation of Negative_regulation of Sp1 1 0.30 0.65 0.2
164 INT253542 Positive_regulation of Phosphorylation of Sp1 1 0.27 1.16 0.2
165 INT136452 Negative_regulation of Negative_regulation of Sp3 1 0.28 0.65 0.2
166 INT121819 Regulation of Binding of STAT1 1 0.59 0.05 0.19
167 INT167940 Regulation of Stat5b 1 0.43 0 0.19
168 INT311891 Phosphorylation of Smad1 4 0.51 1.34 0.18
169 INT271262 Negative_regulation of Negative_regulation of Stat1 2 0.42 1.4 0.18
170 INT188215 Negative_regulation of Phosphorylation of STAT1 2 0.31 0.48 0.17
171 INT162939 Binding of Tfap2a 1 0.26 0.34 0.17
172 INT162940 Negative_regulation of Tfap2a 1 0.32 0.34 0.17
173 INT184024 Binding of Stat5a 1 0.25 0.11 0.17
174 INT190558 Negative_regulation of Localization of Maz 1 0.21 0.61 0.17
175 INT190574 Localization of Maz 1 0.37 0.6 0.17
176 INT102793 Regulation of Phosphorylation of Egr1 1 0.33 0 0.17
177 INT184055 Positive_regulation of Binding of Stat5a 1 0.33 0.12 0.17
178 INT162941 Negative_regulation of Binding of Tfap2a 1 0.32 0.34 0.17
179 INT185254 Gene_expression of Pax6 14 0.72 1.77 0.16
180 INT136454 Positive_regulation of Gene_expression of Sp3 1 0.33 0.44 0.16
181 INT350667 Positive_regulation of Transcription of Stat5a 1 0.29 0.47 0.16
182 INT350637 Transcription of Stat5a 1 0.40 0.46 0.16
183 INT216152 Binding of MTF1 2 0.23 0.41 0.15
184 INT180592 Negative_regulation of Gene_expression of HEYL 1 0.03 0.3 0.15
185 INT310174 Positive_regulation of Smad1 9 0.45 2.16 0.14
186 INT231559 Negative_regulation of Gene_expression of STAT1 2 0.06 0.36 0.14
187 INT177847 Positive_regulation of MTF1 2 0.29 0.48 0.13
188 INT200261 Positive_regulation of Transcription of Sp3 1 0.42 0 0.13
189 INT200280 Transcription of Sp3 1 0.57 0 0.13
190 INT194746 Phosphorylation of Gata3 1 0.10 0.08 0.12
191 INT180593 Positive_regulation of Gene_expression of HEYL 1 0.03 0.18 0.12
192 INT346814 Phosphorylation of Egr1 1 0.62 0 0.12
193 INT220368 Negative_regulation of Positive_regulation of Stat5a 1 0.34 0.46 0.11
194 INT317884 Transcription of Mtf1 1 0.63 1.02 0.11
195 INT186065 Positive_regulation of Phosphorylation of STAT1 3 0.25 1.95 0.1
196 INT200268 Positive_regulation of Binding of Sp3 2 0.39 0.8 0.1
197 INT346807 Regulation of Transcription of Egr1 1 0.44 0.27 0.09
198 INT253546 Positive_regulation of Phosphorylation of Sp3 1 0.29 0.42 0.09
199 INT235781 Positive_regulation of PAX6 2 0.50 0.36 0.08
200 INT283695 Binding of Sox11 1 0.32 0.18 0.08
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