GO:0000982

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Name RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
Categary Function
Go Slim No
Go Link GO:0000982
Unique Molecular Interactions 188
Total Molecular Interactions 232
Total Single Events 1612
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity. They are ordered first by their pain relevance and then by number of times they were reported for RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT335405 Binding of Arntl and Npas2 1 0.28 1.82 1.61
2 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
3 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
4 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
5 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
6 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
7 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92
8 INT335404 Binding of Arntl and Hspg2 1 0.06 0.93 0.82
9 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
10 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
11 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
12 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
13 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
14 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
15 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
16 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
17 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
18 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
19 INT92026 Egr1 Positive_regulation of Fos 1 0.50 0.61 0.67
20 INT312106 EGR1 Regulation of Gene_expression of PTGES 1 0.31 1.06 0.64
21 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
22 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
23 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57
24 INT249001 Gabrg1 Positive_regulation of Arntl 1 0.29 0 0.55
25 INT249006 Gabrg1 Positive_regulation of Transcription of Arntl 1 0.31 0 0.55
26 INT261478 Positive_regulation of Ephb1 Regulation of Gene_expression of Egr1 1 0.10 0.23 0.55
27 INT248997 Gabrg1 Positive_regulation of Clock 1 0.37 0 0.54
28 INT248995 Gabrg1 Regulation of Transcription of Clock 1 0.36 0 0.54
29 INT249016 Gabrg1 Positive_regulation of Transcription of Clock 1 0.37 0 0.54
30 INT304576 Binding of Arntl and Clock 6 0.37 0.43 0.5
31 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
32 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
33 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
34 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
35 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
36 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
37 INT249011 Gabrg1 Regulation of Clock 1 0.19 0 0.43
38 INT130930 Egr1 Negative_regulation of Positive_regulation of Thbs1 1 0.58 0.64 0.38
39 INT249004 Helt Regulation of Clock 1 0.01 0.09 0.37
40 INT249015 Regulation of Helt Regulation of Clock 1 0.01 0.09 0.37
41 INT123495 Negative_regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
42 INT123493 Regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
43 INT90722 Nr4a1 Positive_regulation of Egr1 1 0.20 0.48 0.35
44 INT168202 Msx1 Negative_regulation of Gene_expression of Mc1r 1 0.21 0.49 0.35
45 INT312124 EGR1 Regulation of Binding of PTGES 1 0.31 0.41 0.35
46 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35
47 INT90724 Egr3 Positive_regulation of Egr1 1 0.33 0.48 0.35
48 INT144966 MAPK1 Positive_regulation of Localization of EGR1 1 0.08 0.83 0.35
49 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
50 INT126097 Ddc Positive_regulation of Egr1 1 0.08 0 0.32
51 INT74334 Penk Regulation of Transcription of Egr1 1 0.40 0.25 0.29
52 INT75056 Binding of MC1R and Msx1 1 0.00 0.17 0.29
53 INT74336 Crh Regulation of Transcription of Egr1 1 0.49 0.24 0.28
54 INT147356 Egr1 Positive_regulation of Gene_expression of Btg1 1 0.14 1.56 0.28
55 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
56 INT147358 Egr1 Positive_regulation of Gene_expression of Gdf15 1 0.14 1.56 0.28
57 INT58182 Fos Regulation of Egr1 1 0.49 0.09 0.27
58 INT147359 Positive_regulation of Pik3cd Positive_regulation of Egr1 1 0.09 1.51 0.27
59 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
60 INT130931 Sis Negative_regulation of Egr1 1 0.01 0.52 0.27
61 INT58176 Junb Regulation of Egr1 1 0.46 0.09 0.27
62 INT147360 Pik3cd Positive_regulation of Egr1 1 0.12 1.51 0.27
63 INT125521 EGR1 Regulation of GDF15 1 0.13 0.47 0.26
64 INT168203 Binding of Mc1r and Msx1 1 0.19 0.64 0.25
65 INT98631 Negative_regulation of VEGFA Positive_regulation of EGR1 1 0.44 0.18 0.24
66 INT130060 PPARG Positive_regulation of Positive_regulation of Egr1 1 0.22 0.46 0.24
67 INT98630 VEGFA Positive_regulation of EGR1 1 0.52 0.18 0.24
68 INT144967 MAPK1 Positive_regulation of Positive_regulation of EGR1 1 0.08 0.63 0.24
69 INT184162 Egr1 Positive_regulation of Transcription of Ptges2 1 0.08 0.42 0.22
70 INT184160 Binding of Egr1 and Ptges2 1 0.07 0.4 0.22
71 INT271853 Ngf Positive_regulation of Gene_expression of Egr1 1 0.53 1.36 0.21
72 INT75057 Binding of POMC and Msx1 2 0.39 0.6 0.2
73 INT259817 Ltp Positive_regulation of Egr1 1 0.03 0.28 0.2
74 INT259812 Gtf3a Regulation of Egr1 1 0.01 0.58 0.19
75 INT184159 Egr1 Positive_regulation of Ptges2 1 0.07 0.34 0.19
76 INT58178 Gtf3a Positive_regulation of Egr1 1 0.07 0.09 0.19
77 INT184161 Negative_regulation of Egr1 Positive_regulation of Ptges2 1 0.07 0.34 0.19
78 INT259814 Binding of Arc and Egr1 1 0.34 0.55 0.19
79 INT259813 Binding of Egr1 and Arc 1 0.32 0.55 0.19
80 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19
81 INT58181 Gtf3a Positive_regulation of Gene_expression of Egr1 1 0.07 0.1 0.19
82 INT312090 EGR1 Regulation of Positive_regulation of PTGES 1 0.42 0.21 0.18
83 INT317895 Fos Regulation of Transcription of Egr1 1 0.41 1.03 0.17
84 INT317897 Egr1 Regulation of Transcription of Fosb 1 0.34 1.08 0.17
85 INT317892 Egr1 Regulation of Transcription of Fos 1 0.41 1.03 0.17
86 INT312109 ELANE Positive_regulation of EGR1 1 0.15 0.23 0.16
87 INT312100 ELANE Positive_regulation of Binding of EGR1 1 0.16 0.23 0.16
88 INT146025 EGR1 Negative_regulation of Gene_expression of GDF15 1 0.28 0.81 0.15
89 INT97547 KITLG Negative_regulation of Msx1 1 0.00 0.08 0.15
90 INT97542 Pomc Negative_regulation of Msx1 1 0.13 0.07 0.15
91 INT312092 ELANE Positive_regulation of Gene_expression of EGR1 1 0.19 0.21 0.15
92 INT168806 Tlr4 Positive_regulation of Gene_expression of Egr1 1 0.18 0.3 0.15
93 INT97545 Gtf3a Negative_regulation of Msx1 1 0.02 0.08 0.15
94 INT115140 PPARG Positive_regulation of EGR1 1 0.36 0.45 0.13
95 INT247267 Binding of Egr1 and Mecp2 1 0.12 0.18 0.13
96 INT321408 INS Positive_regulation of EGR1 1 0.03 2.36 0.13
97 INT115141 TGM7 Positive_regulation of EGR1 1 0.26 0.44 0.13
98 INT321414 INS Positive_regulation of Transcription of EGR1 1 0.03 2.36 0.13
99 INT321410 EGR1 Negative_regulation of Gene_expression of TNFSF10 1 0.10 2.07 0.12
100 INT214150 Binding of Mc3r and Msx1 1 0.03 0.5 0.12
101 INT154803 Gene_expression of EGR1 Positive_regulation of Positive_regulation of GDF15 1 0.33 0.84 0.12
102 INT332893 Ppara Regulation of Gene_expression of Arntl 1 0.43 0 0.11
103 INT281022 Clock Negative_regulation of Per1 1 0.26 0.09 0.11
104 INT214152 Binding of Mc4r and Msx1 1 0.03 0.24 0.11
105 INT281023 Clock Negative_regulation of Per2 1 0.31 0.09 0.11
106 INT214168 Msx1 Positive_regulation of Gene_expression of DST 1 0.00 0.13 0.09
107 INT288374 Binding of MLANA and Msx1 1 0.09 0 0.08
108 INT191758 ROS1 Positive_regulation of TFAP2A 1 0.01 0.54 0.08
109 INT216130 SRF Positive_regulation of Gene_expression of EGR1 1 0.49 0.32 0.07
110 INT267016 Bdnf Positive_regulation of Egr1 1 0.12 0.09 0.07
111 INT129184 Gene_expression of EGR1 Positive_regulation of ATF3 1 0.72 0.22 0.07
112 INT332897 Ppara Regulation of Transcription of Clock 1 0.24 0.31 0.06
113 INT262214 Binding of Msx2 and Nr1i2 1 0.19 0.55 0.06
114 INT332880 Arntl Regulation of Ppara 1 0.29 0 0.06
115 INT129183 EGR1 Negative_regulation of Positive_regulation of ATF3 1 0.44 0.19 0.06
116 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06
117 INT332900 Ppara Regulation of Clock 1 0.21 0 0.05
118 INT214146 Msx1 Positive_regulation of Gene_expression of Nucb2 1 0.05 0.19 0.05
119 INT213608 Binding of PER2 and CLOCK 1 0.22 0.65 0.04
120 INT332888 Binding of Arntl and Ppara 1 0.34 0 0.04
121 INT60221 Agt Regulation of Gene_expression of Egr1 1 0.42 0 0.04
122 INT213607 Binding of CSNK1D and CLOCK 1 0.27 0.65 0.04
123 INT332889 Clock Regulation of Ppara 1 0.12 0 0.04
124 INT290810 Gsk3b Regulation of Arntl 1 0.15 0 0.04
125 INT332886 Binding of Clock and Ppara 1 0.32 0 0.04
126 INT243766 Binding of Egr1 and Proc 1 0.01 0.2 0.03
127 INT290808 Gsk3b Positive_regulation of Arntl 1 0.25 0.17 0.03
128 INT213606 CLOCK Regulation of Gene_expression of PROK2 1 0.20 0.3 0
129 INT290813 Arntl Positive_regulation of Gene_expression of Clock 1 0.21 0 0
130 INT332887 Clock Positive_regulation of Ppara 1 0.71 0 0
131 INT262172 Nr1i2 Regulation of Msx2 1 0.12 0.53 0
132 INT184955 EGR1 Regulation of Regulation of TGFB1 1 0.39 0.3 0
133 INT336537 Binding of Clock and Cry2 1 0.32 0 0
134 INT332409 Egr1 Regulation of Hgf 1 0.26 0.14 0
135 INT175732 Binding of ARNTL and ARMC9 1 0.02 0.06 0
136 INT177793 EGR1 Positive_regulation of Negative_regulation of TP53 1 0.18 0.44 0
137 INT240122 Nab2 Regulation of Egr1 1 0.09 0.59 0
138 INT332408 Binding of Egr1 and Hgf 1 0.35 0.14 0
139 INT243770 Egr1 Regulation of Nab2 1 0.28 0.09 0
140 INT353197 ARNTL Regulation of Hlf 1 0.29 0.33 0
141 INT245820 Binding of Sp1 and Tfap2a 1 0.03 0.64 0
142 INT336532 Binding of Arntl and Arntl2 1 0.41 0 0
143 INT290809 Binding of Arntl and Gsk3b 1 0.20 0 0
144 INT336530 Positive_regulation of Binding of Clock and Arntl2 1 0.47 0 0
145 INT332884 Clock Regulation of Gene_expression of Ppara 1 0.63 0.06 0
146 INT312114 EGR1 Positive_regulation of Positive_regulation of PTGES 1 0.32 0 0
147 INT259811 Narp Positive_regulation of Gene_expression of Egr1 1 0.26 0.86 0
148 INT353195 ARNTL Regulation of Gene_expression of Tef 1 0.22 0.33 0
149 INT336536 Binding of Arntl and Cry1 1 0.37 0 0
150 INT175729 Binding of ARNTL and PER1 1 0.19 0.07 0
151 INT296999 Binding of EPS15 and TFAP2A 1 0.06 0.2 0
152 INT336531 Positive_regulation of Binding of Arntl and Arntl2 1 0.55 0 0
153 INT175730 Binding of CLOCK and ARMC9 1 0.02 0.06 0
154 INT245828 Binding of VEGFA and Tfap2a 1 0.01 0.64 0
155 INT269014 Binding of EGR1 and COPD 1 0.12 0.96 0
156 INT332883 Binding of Clock and Tcf12 1 0.02 0 0
157 INT332882 Ncor1 Negative_regulation of Gene_expression of Arntl 1 0.31 0.17 0
158 INT170417 Arntl Regulation of Transcription of Timeless 1 0.08 0 0
159 INT332878 Hdac3 Negative_regulation of Gene_expression of Arntl 1 0.42 0.17 0
160 INT353196 ARNTL Regulation of Tef 1 0.36 0.32 0
161 INT336535 Binding of Clock and Arntl2 1 0.35 0 0
162 INT170416 Binding of Ccrn4l and Clock 1 0.28 0.12 0
163 INT178982 Binding of Clock and Npas2 1 0.14 0.08 0
164 INT213609 CLOCK Regulation of PROK2 1 0.20 0.3 0
165 INT286770 Skil Negative_regulation of Egr1 1 0.08 0.75 0
166 INT336533 Binding of Clock and Cry1 1 0.32 0 0
167 INT281021 Ugcg Regulation of Clock 1 0.07 0 0
168 INT170419 Clock Regulation of Transcription of Timeless 1 0.08 0 0
169 INT175728 Binding of PER1 and CLOCK 1 0.18 0.07 0
170 INT353198 ARNTL Regulation of Dbp 1 0.32 0.32 0
171 INT285641 Zfp36 Negative_regulation of Egr1 1 0.06 0.28 0
172 INT353194 ARNTL Regulation of Localization of Ahr 1 0.27 0.32 0
173 INT336534 Binding of Arntl and Cry2 1 0.37 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity. They are ordered first by their pain relevance and then by number of times they were reported in RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
2 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
3 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
4 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95
5 INT57878 Positive_regulation of Gene_expression of Egr1 36 0.70 20.42 14.45
6 INT149818 Gene_expression of Clock 81 0.70 14.15 10.04
7 INT49660 Positive_regulation of EGR1 54 0.69 32.17 9.89
8 INT57876 Positive_regulation of Egr1 46 0.70 25.6 9.41
9 INT73021 Gene_expression of EGR1 43 0.77 24.65 9.18
10 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
11 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
12 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
13 INT159518 Gene_expression of Clock 4 0.35 2.34 6.91
14 INT73022 Positive_regulation of Gene_expression of EGR1 21 0.69 10.61 6.5
15 INT170385 Regulation of Clock 29 0.49 4.95 6.39
16 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38
17 INT47704 Regulation of Egr1 17 0.60 2.43 5.18
18 INT47706 Negative_regulation of Positive_regulation of Egr1 9 0.41 6.11 5.1
19 INT57376 Transcription of EGR1 20 0.69 12.94 4.84
20 INT51944 Positive_regulation of Transcription of Egr1 12 0.49 1.96 4.72
21 INT117936 Regulation of Gene_expression of Egr1 18 0.60 9.37 4.45
22 INT123502 Binding of Egr1 11 0.35 6.7 3.77
23 INT351263 Binding of CLOCK 1 0.18 0.46 2.71
24 INT128328 Gene_expression of Arntl 44 0.74 3.77 2.63
25 INT96640 Negative_regulation of Gene_expression of Egr1 13 0.43 7.22 2.48
26 INT98634 Positive_regulation of Positive_regulation of EGR1 9 0.68 3.43 2.47
27 INT32920 Gene_expression of Msx1 19 0.71 4.24 2.42
28 INT74262 Negative_regulation of Egr1 15 0.57 7.51 2.41
29 INT15243 Regulation of Egr1 19 0.61 7.6 2.13
30 INT80599 Regulation of Positive_regulation of Egr1 3 0.28 0.46 2.09
31 INT73023 Binding of EGR1 7 0.48 4.23 1.86
32 INT170387 Transcription of Clock 11 0.63 1.78 1.83
33 INT57375 Regulation of EGR1 5 0.40 1.94 1.78
34 INT57875 Positive_regulation of Positive_regulation of Egr1 6 0.49 2.74 1.75
35 INT57877 Negative_regulation of Positive_regulation of Egr1 4 0.42 1.63 1.57
36 INT149815 Positive_regulation of Gene_expression of Clock 7 0.46 0.87 1.45
37 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
38 INT53003 Positive_regulation of Positive_regulation of Egr1 6 0.64 2.36 1.44
39 INT248979 Transcription of Arntl 15 0.69 3.47 1.43
40 INT128316 Regulation of Gene_expression of Arntl 6 0.43 0.68 1.43
41 INT98635 Negative_regulation of Gene_expression of EGR1 5 0.58 2.2 1.42
42 INT248976 Positive_regulation of Clock 8 0.48 0.15 1.38
43 INT141344 Transcription of Egr1 11 0.70 5.59 1.34
44 INT290803 Binding of Arntl 10 0.37 1.82 1.34
45 INT138726 Positive_regulation of Gene_expression of Msx1 5 0.53 1.73 1.2
46 INT98633 Negative_regulation of Transcription of EGR1 3 0.43 0.79 1.11
47 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
48 INT123503 Positive_regulation of Binding of Egr1 3 0.13 2.34 1.04
49 INT123501 Negative_regulation of Binding of Egr1 2 0.12 2.04 0.99
50 INT51947 Regulation of Transcription of Egr1 2 0.59 0.15 0.96
51 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
52 INT351266 Regulation of Binding of CLOCK 1 0.21 0 0.92
53 INT98638 Positive_regulation of Transcription of EGR1 3 0.49 2.83 0.91
54 INT206673 Positive_regulation of Arntl 12 0.67 0.45 0.85
55 INT175747 Regulation of CLOCK 4 0.21 0.06 0.84
56 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
57 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
58 INT248971 Binding of Clock 8 0.34 1.12 0.73
59 INT98636 Negative_regulation of Positive_regulation of EGR1 3 0.58 2.21 0.73
60 INT95617 Regulation of Msx1 2 0.56 1.05 0.73
61 INT6050 Localization of Egr1 4 0.68 0.53 0.7
62 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
63 INT141341 Binding of Egr1 5 0.48 2.65 0.67
64 INT75043 Binding of Msx1 6 0.35 2.36 0.65
65 INT102686 Phosphorylation of Egr1 3 0.59 2.57 0.64
66 INT248964 Positive_regulation of Transcription of Arntl 3 0.48 0.25 0.63
67 INT248978 Localization of Clock 1 0.70 0.3 0.61
68 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
69 INT80300 Gene_expression of TFAP2A 5 0.54 2.76 0.59
70 INT32921 Positive_regulation of Msx1 4 0.47 0.99 0.57
71 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
72 INT73020 Positive_regulation of Binding of EGR1 1 0.49 0.46 0.56
73 INT98632 Negative_regulation of EGR1 6 0.42 3.38 0.54
74 INT81061 Regulation of Negative_regulation of Egr1 1 0.22 0 0.53
75 INT206674 Positive_regulation of Gene_expression of Arntl 6 0.67 0.6 0.52
76 INT292834 Negative_regulation of Gene_expression of Arntl 6 0.43 0.87 0.49
77 INT168801 Localization of Egr1 4 0.78 0.7 0.48
78 INT141342 Negative_regulation of Transcription of Egr1 4 0.43 2.39 0.45
79 INT204005 Negative_regulation of Gene_expression of Clock 3 0.39 0.58 0.45
80 INT175759 Gene_expression of ARNTL 9 0.75 0.8 0.44
81 INT304570 Regulation of Binding of Arntl 2 0.26 0.35 0.43
82 INT304572 Regulation of Binding of Clock 1 0.30 0.29 0.43
83 INT247307 Negative_regulation of Msx1 3 0.22 0.11 0.42
84 INT204013 Phosphorylation of Arntl 2 0.63 1.02 0.41
85 INT243756 Regulation of Positive_regulation of Egr1 7 0.45 1.18 0.4
86 INT196973 Regulation of Gene_expression of Clock 12 0.38 3.58 0.38
87 INT80302 Binding of TFAP2A 7 0.39 1.67 0.38
88 INT106402 Positive_regulation of TFAP2A 2 0.13 0.35 0.35
89 INT144968 Positive_regulation of Localization of EGR1 1 0.69 0.82 0.35
90 INT144970 Localization of EGR1 1 0.80 0.82 0.34
91 INT173635 Negative_regulation of TFAP2A 3 0.34 2.93 0.33
92 INT188498 Negative_regulation of Transcription of Egr1 3 0.41 0.14 0.32
93 INT292207 Negative_regulation of Gene_expression of TFAP2A 1 0.05 1.2 0.27
94 INT214128 Negative_regulation of Gene_expression of Msx1 3 0.53 1.25 0.26
95 INT177838 Regulation of Gene_expression of EGR1 2 0.17 2.38 0.25
96 INT281018 Regulation of Arntl 12 0.47 0.81 0.24
97 INT141343 Positive_regulation of Transcription of Egr1 1 0.47 1.43 0.24
98 INT290800 Protein_catabolism of Arntl 1 0.76 0.84 0.21
99 INT346813 Positive_regulation of Regulation of Egr1 1 0.49 0.27 0.21
100 INT162939 Binding of Tfap2a 1 0.26 0.34 0.17
101 INT162940 Negative_regulation of Tfap2a 1 0.32 0.34 0.17
102 INT102793 Regulation of Phosphorylation of Egr1 1 0.33 0 0.17
103 INT162941 Negative_regulation of Binding of Tfap2a 1 0.32 0.34 0.17
104 INT115159 Regulation of Positive_regulation of EGR1 1 0.20 0.18 0.16
105 INT290777 Phosphorylation of Clock 1 0.42 0.41 0.14
106 INT214127 Localization of Msx1 1 0.06 0.21 0.13
107 INT292828 Regulation of Transcription of Arntl 2 0.43 0.48 0.12
108 INT346814 Phosphorylation of Egr1 1 0.62 0 0.12
109 INT290793 Negative_regulation of Clock 6 0.39 1.48 0.09
110 INT346807 Regulation of Transcription of Egr1 1 0.44 0.27 0.09
111 INT290792 Negative_regulation of Binding of Arntl 2 0.41 0 0.08
112 INT270605 Regulation of Arntl2 1 0.35 0.91 0.08
113 INT290778 Negative_regulation of Transcription of Arntl 3 0.45 0.88 0.07
114 INT290782 Regulation of Phosphorylation of Arntl 1 0.34 0.11 0.07
115 INT320268 Positive_regulation of Negative_regulation of EGR1 1 0.26 0.69 0.07
116 INT175751 Localization of CLOCK 1 0.40 0 0.07
117 INT296212 Negative_regulation of CLOCK 1 0.04 0.24 0.07
118 INT97754 Regulation of Gene_expression of TFAP2A 1 0.36 0.13 0.06
119 INT217904 Regulation of Gene_expression of ARNTL 1 0.14 0 0.04
120 INT290801 Regulation of Protein_catabolism of Clock 1 0.12 0.1 0.04
121 INT290785 Protein_catabolism of Clock 1 0.29 0.1 0.04
122 INT290797 Negative_regulation of Phosphorylation of Arntl 1 0.45 0 0.03
123 INT290774 Regulation of Protein_catabolism of Arntl 1 0.21 0.32 0.03
124 INT290784 Regulation of Localization of Arntl 1 0.47 0.06 0.03
125 INT290802 Positive_regulation of Protein_catabolism of Arntl 1 0.38 0 0.03
126 INT290791 Localization of Arntl 1 0.61 0.06 0.03
127 INT206911 Gene_expression of Msx2 4 0.71 1.26 0
128 INT175738 Regulation of ARNTL 4 0.28 0.29 0
129 INT206909 Negative_regulation of Gene_expression of Msx2 2 0.53 0.29 0
130 INT157237 Gene_expression of CLOCK 2 0.58 0.2 0
131 INT178976 Binding of Clock 1 0.22 0.06 0
132 INT332854 Negative_regulation of Arntl 1 0.49 0.47 0
133 INT206916 Positive_regulation of Gene_expression of Msx2 1 0.40 0.36 0
134 INT220772 Transcription of Msx2 1 0.46 0.08 0
135 INT175755 Positive_regulation of CLOCK 1 0.37 0.12 0
136 INT173648 Regulation of Binding of TFAP2A 1 0.03 0.32 0
137 INT336529 Negative_regulation of Binding of Clock 1 0.32 0 0
138 INT204008 Regulation of Transcription of Clock 1 0.12 0.1 0
139 INT217909 Negative_regulation of Gene_expression of ARNTL 1 0.22 0 0
140 INT173631 Negative_regulation of Positive_regulation of TFAP2A 1 0.05 0.27 0
141 INT175749 Positive_regulation of Regulation of CLOCK 1 0.25 0.06 0
142 INT217906 Positive_regulation of Gene_expression of ARNTL 1 0.25 0 0
143 INT290796 Positive_regulation of Phosphorylation of Arntl 1 0.53 0 0
144 INT175740 Positive_regulation of ARNTL 1 0.43 0.12 0
145 INT178971 Regulation of Clock 1 0.14 0.1 0
146 INT173627 Negative_regulation of Binding of TFAP2A 1 0.08 0.28 0
147 INT285638 Regulation of Negative_regulation of Egr1 1 0.37 0.14 0
148 INT173642 Transcription of TFAP2A 1 0.09 0.27 0
149 INT157246 Negative_regulation of Transcription of CLOCK 1 0.41 0.09 0
150 INT173645 Regulation of TFAP2A 1 0.02 0.33 0
151 INT173630 Positive_regulation of Transcription of TFAP2A 1 0.06 0.54 0
152 INT311630 Negative_regulation of Tfap2a 1 0.34 0.23 0
153 INT157240 Transcription of CLOCK 1 0.67 0.09 0
154 INT319128 Positive_regulation of Binding of Tfap2a 1 0.23 0.5 0
155 INT311626 Negative_regulation of Gene_expression of Tfap2a 1 0.34 0.29 0
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