GO:0001046

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Name core promoter sequence-specific DNA binding
Categary Function
Go Slim No
Go Link GO:0001046
Unique Molecular Interactions 230
Total Molecular Interactions 322
Total Single Events 2566
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for core promoter sequence-specific DNA binding. They are ordered first by their pain relevance and then by number of times they were reported for core promoter sequence-specific DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
2 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
3 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
4 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
5 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
6 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16
7 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
8 INT200307 Rest Negative_regulation of Rorb 1 0.00 0.1 1.03
9 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
10 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
11 INT200308 Binding of Rest and Rorb 1 0.00 0 0.87
12 INT200317 Rest Negative_regulation of Transcription of Oprm1 1 0.31 0 0.64
13 INT109802 Binding of Esr2 and Oprl1 1 0.22 0.1 0.59
14 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
15 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
16 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5
17 INT200321 Binding of Rest and Negative_regulation of Gene_expression of Oprm1 1 0.36 0.05 0.49
18 INT261374 Nsdhl Regulation of Esr2 1 0.05 0.76 0.41
19 INT200327 Oprm1 Negative_regulation of Gene_expression of Rest 1 0.31 0 0.41
20 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41
21 INT200314 Oprm1 Regulation of Rest 1 0.20 0.1 0.39
22 INT200353 Rest Negative_regulation of Oprm1 1 0.31 0.1 0.39
23 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38
24 INT200302 Rest Regulation of Rorb 1 0.00 0.07 0.38
25 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
26 INT245328 Binding of Esr2 and Pgr 1 0.03 0.41 0.37
27 INT200333 Binding of Rest and Sp1 1 0.24 0.07 0.35
28 INT291555 Binding of ESR1 and Dlat 1 0.01 0.6 0.35
29 INT200316 Sp1 Regulation of Gene_expression of Rest 1 0.31 0 0.35
30 INT200352 Binding of Rest and Rcor2 1 0.16 0.44 0.34
31 INT291554 Binding of ESR1 and St8sia2 1 0.01 0.49 0.33
32 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3
33 INT200351 Sp1 Positive_regulation of Gene_expression of Rest 1 0.34 0.07 0.3
34 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
35 INT158734 Esr1 Regulation of Esrrb 1 0.00 0.28 0.29
36 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
37 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28
38 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28
39 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27
40 INT323152 Binding of DBT and ESR1 2 0.02 1.29 0.27
41 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26
42 INT317773 Positive_regulation of GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
43 INT317775 GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
44 INT186783 Binding of ESR1 and NRIP1 1 0.31 0.79 0.25
45 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
46 INT199971 IL6 Positive_regulation of ESR1 1 0.08 0.84 0.24
47 INT200309 Positive_regulation of Binding of Rest and Sp3 1 0.41 0.88 0.24
48 INT197590 Esr2 Positive_regulation of Negative_regulation of Pgr 1 0.16 0 0.24
49 INT159163 Binding of Esr2 and Regulation of Gper 1 0.41 0.27 0.23
50 INT63203 INS Positive_regulation of ESR1 1 0.09 0.3 0.23
51 INT97691 Binding of REST and HDAC9 1 0.26 0.09 0.23
52 INT261389 Nsdhl Positive_regulation of Esr2 1 0.06 1.04 0.23
53 INT63198 POMC Positive_regulation of ESR1 1 0.14 0.3 0.23
54 INT270135 Binding of ESR1 and RALA 1 0.11 0.37 0.22
55 INT63192 PTH Positive_regulation of ESR1 1 0.20 0.29 0.22
56 INT97694 Ngf Negative_regulation of Gene_expression of REST 1 0.01 0.09 0.21
57 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19
58 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19
59 INT192219 CASP3 Regulation of ESR1 1 0.03 1.19 0.19
60 INT19042 ESR1 Positive_regulation of GGT5 1 0.03 0.6 0.17
61 INT19045 ESR1 Positive_regulation of Salpa1 1 0.02 0.6 0.17
62 INT104797 Smarce1 Positive_regulation of REST 1 0.01 0.24 0.15
63 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15
64 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15
65 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15
66 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15
67 INT181752 Binding of CPOX and ESR1 1 0.02 0.89 0.14
68 INT291644 Binding of DST and ESR1 1 0.05 0.84 0.14
69 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13
70 INT86429 Binding of Hspb1 and Esr1 1 0.19 0.26 0.13
71 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13
72 INT200338 Rest Positive_regulation of Gene_expression of Oprm1 1 0.36 0 0.13
73 INT341827 Binding of ESR1 and TNC 1 0.14 0.63 0.11
74 INT341775 DBT Regulation of Binding of ESR1 1 0.02 0.1 0.11
75 INT252779 Binding of ESR1 and RAF1 1 0.01 2.03 0.11
76 INT153637 Gene_expression of REST Positive_regulation of Gene_expression of Oprm1 1 0.03 0.08 0.1
77 INT279407 Binding of ESR1 and IGKV2-19 1 0.02 0.4 0.1
78 INT153636 Binding of REST and Oprm1 1 0.02 0.09 0.09
79 INT341776 ESR1 Positive_regulation of Gene_expression of SLC6A3 1 0.06 0.08 0.09
80 INT52836 ESR1 Positive_regulation of HSD17B7 1 0.43 0.41 0.09
81 INT238628 Mef2c Regulation of Gene_expression of Arc 1 0.09 0.16 0.08
82 INT238625 Mef2c Regulation of Gene_expression of Syngap1 1 0.10 0.16 0.08
83 INT199973 ESR1 Negative_regulation of EEF1B2P2 1 0.01 0.46 0.08
84 INT196213 REST Regulation of Gene_expression of CACNA1A 1 0.46 0.08 0.08
85 INT38188 PGR Positive_regulation of Gene_expression of ESR1 1 0.42 0.22 0.07
86 INT339108 Binding of ESR1 and JUP 1 0.38 0.62 0.07
87 INT224293 AR Positive_regulation of Protein_catabolism of ESR1 1 0.24 0.4 0.07
88 INT206855 Binding of ESR1 and PPARA 1 0.03 1.21 0.07
89 INT272388 Esr1 Regulation of Transcription of Trpv6 1 0.03 0.13 0.06
90 INT197594 Esr1 Regulation of Esr2 1 0.04 0 0.06
91 INT187845 Binding of ESR1 and Esr2 1 0.01 0.17 0.06
92 INT197592 Esr2 Regulation of Esr1 1 0.04 0 0.06
93 INT197586 Esr2 Regulation of Pgr 1 0.09 0 0.06
94 INT206846 ESR1 Regulation of Gene_expression of PLP1 1 0.06 1.02 0.05
95 INT287223 Pdx1 Regulation of Transcription of Insig1 1 0.03 0.56 0.05
96 INT316248 ESR1 Regulation of Gene_expression of TRPM8 1 0.34 0.17 0.05
97 INT244461 CS Positive_regulation of ESR1 1 0.06 1.15 0.05
98 INT235640 Binding of GATA3 and Mrgpre 1 0.01 0.8 0.04
99 INT206848 PLP1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04
100 INT206853 ESR1 Positive_regulation of Gene_expression of PCP4 1 0.08 1.39 0.04
101 INT133983 Pou2f1 Regulation of Pdx1 1 0.06 0 0.04
102 INT133989 Pdx1 Regulation of Kcnip3 1 0.07 0 0.04
103 INT206845 ANXA1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04
104 INT133981 Pdx1 Regulation of Pou1f1 1 0.05 0 0.04
105 INT201445 ESR1 Regulation of Slc6a3 1 0.02 0.05 0.04
106 INT206851 NR4A1 Regulation of Gene_expression of ESR1 1 0.08 0.9 0.04
107 INT206896 ESR1 Positive_regulation of Gene_expression of Nr1i3 1 0.00 0.36 0.04
108 INT133982 Pou1f1 Regulation of Pdx1 1 0.05 0 0.04
109 INT206847 ESR1 Negative_regulation of Gene_expression of PTGER3 1 0.08 1.52 0.04
110 INT197917 Binding of ESR1 and Sh2b2 1 0.01 0 0.04
111 INT133990 Meis1 Regulation of Pdx1 1 0.05 0 0.04
112 INT134000 Pdx1 Regulation of Gene_expression of Npff 1 0.46 0 0.04
113 INT133978 Pdx1 Regulation of Pou2f1 1 0.06 0 0.04
114 INT134001 Kcnip3 Regulation of Pdx1 1 0.07 0 0.04
115 INT206849 ESR1 Regulation of Gene_expression of ALDH1A1 1 0.11 2.26 0.04
116 INT322891 Sox9 Regulation of Transcription of Col2a1 1 0.10 0.12 0.04
117 INT206852 ESR1 Regulation of Gene_expression of CRABP2 1 0.08 1.52 0.04
118 INT133996 Pdx1 Regulation of Meis1 1 0.05 0 0.04
119 INT183614 Binding of ESR1 and TMED4 2 0.02 0.13 0.03
120 INT184208 IL1B Negative_regulation of SOX9 1 0.32 0 0.03
121 INT278289 Binding of DBP and ESR1 1 0.03 0.82 0.03
122 INT213902 ESR1 Positive_regulation of EGFR 1 0.48 0.31 0.03
123 INT245075 Binding of ESR1 and NR4A1 1 0.01 1.08 0.03
124 INT290437 Gene_expression of Mef2c Negative_regulation of Upf1 1 0.02 0.25 0.03
125 INT200311 Htt Positive_regulation of Rest 1 0.05 0.75 0.03
126 INT210260 Sox9 Negative_regulation of Cdx2 1 0.20 0 0.03
127 INT278294 Binding of ESR1 and SHBG 1 0.01 0.82 0.03
128 INT213905 ESR1 Positive_regulation of SRC 1 0.14 0.31 0.03
129 INT192914 Binding of ESR1 and GOPC 2 0.02 0.61 0
130 INT280849 REST Negative_regulation of Gene_expression of Avp 1 0.09 0.09 0
131 INT260342 Binding of Esr1 and Rcc1 1 0.05 0.99 0
132 INT198111 Binding of Esr1 and Esr2 1 0.05 0 0
133 INT335214 Binding of ESR1 and RARS 1 0.08 0.92 0
134 INT178638 Gh1 Regulation of Gene_expression of ESR1 1 0.01 0.47 0
135 INT206895 Binding of ESR1 and Aldh1a1 1 0.03 0 0
136 INT264663 Binding of ESR1 and PRL 1 0.22 0.18 0
137 INT98354 TXNRD1 Positive_regulation of Positive_regulation of ESR1 1 0.00 0.05 0
138 INT196208 REST Regulation of CACNA1A 1 0.46 0.06 0
139 INT206854 ESR1 Regulation of IGF1 1 0.01 0.33 0
140 INT196216 Binding of CACNA1A and REST 1 0.28 0 0
141 INT120549 Binding of ESR1 and Mpo 1 0.26 0.05 0
142 INT320029 Gene_expression of SOX9 Positive_regulation of Gene_expression of COL7A1 1 0.03 0 0
143 INT199975 ESR1 Positive_regulation of PGR 1 0.05 0.11 0
144 INT197677 Binding of ESR1 and Arg1 1 0.04 0 0
145 INT264662 ESR1 Regulation of Gene_expression of PRL 1 0.43 0.21 0
146 INT121179 Binding of Htt and Rest 1 0.07 0.45 0
147 INT336994 CALR Negative_regulation of ESR1 1 0.04 0 0
148 INT206850 Binding of CRABP2 and ESR1 1 0.06 0 0
149 INT245726 SOX9 Regulation of SGCG 1 0.00 0.29 0
150 INT245077 Binding of ESR1 and CXCL12 1 0.06 1.42 0
151 INT313596 ESR1 Positive_regulation of Gene_expression of PGR 1 0.05 1 0
152 INT333879 Shc1 Positive_regulation of SOX9 1 0.01 0 0
153 INT219421 Binding of ESR1 and MALAT1 1 0.34 0.63 0
154 INT225570 Ncoa6 Regulation of Sox9 1 0.16 0.72 0
155 INT314740 Binding of ESR1 and Brca1 1 0.16 0.69 0
156 INT98353 THRB Negative_regulation of Positive_regulation of ESR1 1 0.00 0.09 0
157 INT314773 Glp1r Positive_regulation of Gene_expression of Pdx1 1 0.01 0.57 0
158 INT224291 Negative_regulation of ESR1 Positive_regulation of CCND1 1 0.16 0.07 0
159 INT244457 CS Positive_regulation of Gene_expression of ESR1 1 0.07 0.67 0
160 INT192913 Binding of ESR1 and HAMP 1 0.02 0.72 0
161 INT314687 ESR1 Regulation of PGR 1 0.27 0.88 0
162 INT350706 Binding of Mef2c and Mir223 1 0.02 0.11 0
163 INT197911 Dlst Positive_regulation of Gene_expression of Esr1 1 0.03 0.34 0
164 INT290439 Negative_regulation of Mef2c Positive_regulation of Gene_expression of Ppargc1a 1 0.21 0 0
165 INT333928 Binding of CALR and ESR1 1 0.09 0.09 0
166 INT290441 Mef2c Regulation of Mef2b 1 0.09 0.11 0
167 INT333929 Binding of ESR1 and ERLEC1 1 0.01 0.09 0
168 INT223582 Negative_regulation of MTOR Positive_regulation of Phosphorylation of ESR1 1 0.31 0.67 0
169 INT178639 Binding of ESR1 and Igf1 1 0.02 0.39 0
170 INT197908 Dlst Positive_regulation of Esr1 1 0.03 0.34 0
171 INT49943 Binding of Th and Pdx1 1 0.02 0.17 0
172 INT244450 TMBIM6 Negative_regulation of Gene_expression of ESR1 1 0.04 0.68 0
173 INT260601 Binding of ESR1 and Ppargc1a 1 0.01 0.48 0
174 INT206844 ESR1 Positive_regulation of Gene_expression of ANXA1 1 0.08 0.1 0
175 INT264661 ESR1 Positive_regulation of PRL 1 0.43 0.68 0
176 INT339102 Binding of ESR1 and PVT1 1 0.34 0.3 0
177 INT297213 Myoz1 Regulation of Mef2c 1 0.02 0.09 0
178 INT98356 ADRA1D Positive_regulation of Positive_regulation of ESR1 1 0.02 0.05 0
179 INT290438 Mef2c Regulation of Mef2a 1 0.26 0.11 0
180 INT192915 Binding of ESR1 and MIER3 1 0.00 0.72 0
181 INT219404 Binding of ESR1 and VEGFA 1 0.33 0.63 0
182 INT96975 Binding of Atp7b and Esr1 1 0.07 0.14 0
183 INT279282 Binding of EGFR and ESR2 1 0.45 1.39 0
184 INT252805 ENOPH1 Positive_regulation of Gene_expression of ESR1 1 0.00 2.46 0
185 INT219407 Binding of ESR1 and PCNA 1 0.31 0.31 0
186 INT197676 ESR1 Regulation of Gene_expression of Pgr 1 0.06 0.1 0
187 INT191168 DBT Negative_regulation of ESR1 1 0.02 0 0
188 INT335216 RARS Negative_regulation of Binding of ESR1 1 0.10 0.92 0
189 INT234179 Binding of DDR1 and ESR1 1 0.05 0.86 0
190 INT199988 ESR1 Positive_regulation of Fos 1 0.40 0.18 0
191 INT197675 Regulation of Binding of ESR1 and Arg1 1 0.05 0 0
192 INT244471 TMBIM6 Negative_regulation of ESR1 1 0.04 0.68 0
193 INT289426 Binding of ESR1 and RXFP1 1 0.01 0.18 0
194 INT230148 Binding of ESR1 and Positive_regulation of MAPK1 1 0.07 0 0
195 INT223318 Binding of ESR1 and ESR2 1 0.40 1.22 0
196 INT218012 EE Positive_regulation of ESR1 1 0.03 0 0
197 INT230135 Binding of ESR1 and OSBP 1 0.11 0.08 0
198 INT185268 Binding of Fgf2 and Sox1 1 0.19 0 0
199 INT185272 Binding of Egf and Sox1 1 0.21 0 0
200 INT98355 TXNRD1 Negative_regulation of Positive_regulation of ESR1 1 0.00 0.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for core promoter sequence-specific DNA binding. They are ordered first by their pain relevance and then by number of times they were reported in core promoter sequence-specific DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
2 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
3 INT20462 Binding of ESR1 210 0.44 102.7 26.34
4 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
5 INT92354 Localization of ESR1 77 0.75 33.04 15.51
6 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
7 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
8 INT15687 Regulation of ESR1 91 0.60 40.42 7.95
9 INT110987 Transcription of ESR1 45 0.71 24.16 6.72
10 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69
11 INT97693 Gene_expression of REST 29 0.75 5.51 5.26
12 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84
13 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57
14 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
15 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
16 INT77385 Gene_expression of Esr2 18 0.75 4.69 3.92
17 INT218955 Protein_catabolism of ESR1 9 0.92 3.95 3.74
18 INT200248 Gene_expression of Rest 1 0.66 1.25 3.7
19 INT20461 Binding of Esr1 34 0.48 9.58 3.66
20 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36
21 INT73918 Transcription of Esr1 21 0.66 8.74 3.12
22 INT199255 Binding of Rest 14 0.41 1.43 2.94
23 INT133080 Gene_expression of GATA3 15 0.61 5.64 2.89
24 INT31541 Regulation of Esr1 15 0.54 4.12 2.82
25 INT174727 Positive_regulation of Positive_regulation of ESR1 14 0.44 6.3 2.7
26 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
27 INT108796 Binding of ESR2 5 0.46 6.84 2.36
28 INT102234 Gene_expression of ESR2 17 0.65 9.29 2.3
29 INT109800 Binding of Esr2 8 0.42 1.79 1.93
30 INT73913 Regulation of Gene_expression of Esr1 2 0.41 2.24 1.92
31 INT218959 Negative_regulation of Protein_catabolism of ESR1 3 0.37 0.97 1.9
32 INT96971 Positive_regulation of Gene_expression of Esr1 6 0.46 2.27 1.67
33 INT153635 Positive_regulation of Gene_expression of REST 10 0.54 1.38 1.6
34 INT28367 Positive_regulation of REST 10 0.54 2.07 1.52
35 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
36 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
37 INT116008 Binding of Gata3 2 0.34 1.37 1.41
38 INT165005 Binding of REST 26 0.43 2.81 1.39
39 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
40 INT8511 Localization of Esr1 6 0.80 3.27 1.26
41 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2
42 INT824 Negative_regulation of Negative_regulation of ESR1 3 0.42 1.53 1.18
43 INT133079 Positive_regulation of Gene_expression of GATA3 3 0.50 1.03 1.11
44 INT71906 Regulation of Gene_expression of ESR1 22 0.41 11.01 0.98
45 INT154468 Negative_regulation of Transcription of ESR1 3 0.29 1.14 0.96
46 INT166715 Gene_expression of Sox9 16 0.65 6.39 0.92
47 INT190591 Positive_regulation of Rest 3 0.37 2.52 0.92
48 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
49 INT200255 Localization of Rest 1 0.68 0.14 0.86
50 INT73914 Negative_regulation of Transcription of Esr1 3 0.39 0.75 0.84
51 INT174728 Positive_regulation of Transcription of ESR1 10 0.47 3.3 0.83
52 INT125092 Negative_regulation of Binding of ESR1 8 0.42 4.15 0.82
53 INT145306 Gene_expression of Sox9 5 0.54 2.47 0.8
54 INT158075 Positive_regulation of Esr2 1 0.28 0.5 0.77
55 INT92082 Regulation of Binding of ESR1 5 0.45 2.41 0.73
56 INT116012 Regulation of Positive_regulation of Gata3 1 0.20 0.07 0.71
57 INT73917 Regulation of Transcription of Esr1 4 0.25 1.5 0.7
58 INT116006 Positive_regulation of Transcription of Gata3 1 0.21 0.07 0.7
59 INT116010 Positive_regulation of Binding of Gata3 1 0.31 0.07 0.7
60 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67
61 INT191177 Regulation of Localization of ESR1 7 0.42 2.04 0.64
62 INT202416 Negative_regulation of Gata3 2 0.32 1.17 0.64
63 INT17840 Negative_regulation of GATA3 3 0.41 1.96 0.63
64 INT205470 Positive_regulation of GATA3 4 0.33 2.53 0.61
65 INT290660 Negative_regulation of Gene_expression of Gata3 1 0.25 1.52 0.6
66 INT184222 Negative_regulation of SOX9 7 0.41 2.68 0.58
67 INT157103 Transcription of SOX9 6 0.59 1.2 0.58
68 INT226481 Negative_regulation of Gene_expression of GATA3 1 0.06 1.41 0.57
69 INT200273 Negative_regulation of Rest 1 0.43 0.69 0.55
70 INT133968 Binding of Pdx1 1 0.32 0.16 0.55
71 INT153634 Regulation of REST 4 0.48 1.42 0.54
72 INT144053 Transcription of GATA3 1 0.67 0.89 0.54
73 INT157104 Positive_regulation of SOX9 6 0.66 1.66 0.52
74 INT157105 Positive_regulation of Transcription of SOX9 4 0.58 0.88 0.51
75 INT190899 Negative_regulation of Phosphorylation of ESR1 3 0.33 1.01 0.49
76 INT299799 Negative_regulation of Negative_regulation of GATA3 1 0.09 1.32 0.47
77 INT145304 Regulation of Gene_expression of Sox9 1 0.43 1.04 0.46
78 INT174725 Positive_regulation of Localization of ESR1 8 0.47 2.45 0.41
79 INT109801 Transcription of Esr2 2 0.69 2.08 0.41
80 INT348631 Regulation of Esr2 1 0.40 0.87 0.4
81 INT165006 Positive_regulation of Binding of REST 1 0.23 0.94 0.4
82 INT268930 Regulation of Regulation of Esr1 2 0.41 0.48 0.38
83 INT186535 Negative_regulation of Gene_expression of Esr2 2 0.25 1.07 0.38
84 INT178630 Positive_regulation of Negative_regulation of ESR1 2 0.04 0.64 0.35
85 INT200269 Negative_regulation of Transcription of Rest 1 0.31 0.08 0.35
86 INT194086 Negative_regulation of Gene_expression of ESR2 1 0.03 1.22 0.35
87 INT200245 Transcription of Rest 1 0.51 0.08 0.35
88 INT176586 Positive_regulation of Binding of ESR1 11 0.41 4.64 0.33
89 INT238560 Regulation of Mef2c 9 0.45 2.12 0.33
90 INT156399 Regulation of Pdx1 1 0.00 0.96 0.33
91 INT200270 Regulation of Rest 1 0.20 0.07 0.32
92 INT200256 Negative_regulation of Regulation of Rest 1 0.32 0.07 0.32
93 INT183916 Negative_regulation of Binding of Esr1 1 0.06 0.91 0.32
94 INT73915 Negative_regulation of Negative_regulation of Esr1 1 0.40 0.06 0.31
95 INT153772 Negative_regulation of Localization of ESR1 7 0.54 4.42 0.27
96 INT102801 Regulation of ESR2 1 0.51 0 0.27
97 INT102800 Regulation of Gene_expression of ESR2 1 0.22 0 0.27
98 INT49942 Positive_regulation of Pdx1 5 0.02 1.24 0.26
99 INT332230 Regulation of Pdx1 1 0.01 0.99 0.25
100 INT138751 Localization of ESR2 2 0.72 1.51 0.24
101 INT104789 Negative_regulation of REST 3 0.33 0.44 0.23
102 INT145303 Regulation of Sox9 2 0.28 0.71 0.22
103 INT96972 Positive_regulation of Binding of Esr1 4 0.22 1.35 0.21
104 INT245763 Regulation of SOX9 4 0.43 1.68 0.21
105 INT202355 Transcription of Mef2c 3 0.69 0.6 0.21
106 INT134662 Positive_regulation of Gene_expression of SOX9 9 0.48 1.69 0.19
107 INT186021 Positive_regulation of Positive_regulation of Esr1 1 0.08 0 0.19
108 INT248543 Positive_regulation of Mef2c 7 0.69 2.82 0.18
109 INT176571 Negative_regulation of Positive_regulation of ESR1 5 0.47 3.15 0.17
110 INT200275 Positive_regulation of Gene_expression of Rest 1 0.59 0.92 0.17
111 INT277602 Binding of Mef2c 10 0.39 4.35 0.16
112 INT176461 Protein_catabolism of Esr1 1 0.12 0.37 0.16
113 INT185243 Gene_expression of Sox1 6 0.61 0.91 0.12
114 INT162109 Negative_regulation of Gene_expression of Esr1 4 0.16 2.41 0.12
115 INT194746 Phosphorylation of Gata3 1 0.10 0.08 0.12
116 INT211949 Negative_regulation of Sox9 1 0.31 0.83 0.12
117 INT200281 Negative_regulation of Negative_regulation of Rest 1 0.31 0.44 0.11
118 INT184220 Negative_regulation of Gene_expression of SOX9 4 0.36 0.58 0.09
119 INT123875 Localization of Pdx1 1 0.80 0.28 0.09
120 INT70606 Positive_regulation of Positive_regulation of Pdx1 1 0.02 0.4 0.09
121 INT261361 Negative_regulation of Esr2 1 0.15 0.67 0.09
122 INT202629 Gene_expression of Pdx1 8 0.60 4.09 0.08
123 INT211948 Regulation of Gene_expression of Sox9 2 0.33 0.94 0.08
124 INT196248 Localization of REST 1 0.66 0.15 0.08
125 INT290404 Positive_regulation of Negative_regulation of Mef2c 1 0.50 0.72 0.08
126 INT202649 Positive_regulation of Pdx1 3 0.45 1.45 0.07
127 INT224299 Positive_regulation of Protein_catabolism of ESR1 3 0.64 1.43 0.07
128 INT277578 Regulation of Negative_regulation of Mef2c 2 0.45 1.17 0.07
129 INT178868 Regulation of Positive_regulation of ESR1 1 0.42 0.52 0.07
130 INT210242 Positive_regulation of Sox9 3 0.43 0.35 0.06
131 INT290417 Positive_regulation of Gene_expression of Mef2c 1 0.50 1.25 0.06
132 INT253882 Positive_regulation of Localization of Esr1 1 0.30 1.21 0.06
133 INT211939 Regulation of Sox9 1 0.33 0.35 0.06
134 INT185257 Positive_regulation of Sox1 1 0.39 0 0.05
135 INT197017 Binding of GATA3 2 0.36 0.94 0.04
136 INT272379 Positive_regulation of Transcription of Esr1 1 0.04 0.13 0.04
137 INT290407 Positive_regulation of Binding of Mef2c 1 0.44 0.93 0.04
138 INT225365 Binding of Sox9 2 0.28 0.48 0.03
139 INT145302 Positive_regulation of Sox9 2 0.48 1.42 0.03
140 INT290419 Regulation of Gene_expression of Mef2c 1 0.62 0.41 0.03
141 INT290399 Negative_regulation of Gene_expression of Mef2c 1 0.59 0.59 0.03
142 INT174726 Regulation of Regulation of ESR1 1 0.41 0.73 0.03
143 INT97829 Gene_expression of Pdx1 7 0.32 1.14 0
144 INT162339 Regulation of Gene_expression of SOX9 4 0.32 0.42 0
145 INT245757 Localization of SOX9 4 0.62 0.8 0
146 INT211945 Negative_regulation of Gene_expression of Sox9 3 0.44 0.63 0
147 INT174724 Regulation of Transcription of ESR1 2 0.18 0.49 0
148 INT178629 Positive_regulation of Phosphorylation of ESR1 2 0.36 0.93 0
149 INT322883 Regulation of Transcription of Sox9 1 0.43 0.18 0
150 INT132735 Positive_regulation of Gene_expression of Pdx1 1 0.29 0 0
151 INT202631 Transcription of Pdx1 1 0.48 0 0
152 INT290400 Regulation of Regulation of Mef2c 1 0.45 0.24 0
153 INT185259 Negative_regulation of Gene_expression of Sox1 1 0.34 0 0
154 INT307589 Positive_regulation of Gene_expression of ESR2 1 0.42 0.5 0
155 INT49941 Negative_regulation of Pdx1 1 0.02 0.07 0
156 INT211943 Transcription of Sox9 1 0.50 0.3 0
157 INT323815 Negative_regulation of Transcription of SOX9 1 0.41 0.18 0
158 INT49938 Negative_regulation of Positive_regulation of Pdx1 1 0.02 0.07 0
159 INT290429 Negative_regulation of Negative_regulation of Mef2c 1 0.37 0.05 0
160 INT290425 Negative_regulation of Binding of Mef2c 1 0.37 0 0
161 INT322886 Transcription of Sox9 1 0.50 0.25 0
162 INT138752 Transcription of ESR2 1 0.60 0 0
163 INT235637 Localization of GATA3 1 0.73 0.55 0
164 INT290409 Negative_regulation of Transcription of Mef2c 1 0.43 0.08 0
165 INT145307 Positive_regulation of Positive_regulation of Sox9 1 0.48 0.07 0
166 INT202644 Regulation of Gene_expression of Pdx1 1 0.41 0 0
167 INT223607 Regulation of Phosphorylation of ESR1 1 0.35 0.65 0
168 INT49940 Positive_regulation of Negative_regulation of Pdx1 1 0.02 0.07 0
169 INT245752 Positive_regulation of Binding of SOX9 1 0.41 0.48 0
170 INT196244 Negative_regulation of Gene_expression of REST 1 0.38 0.09 0
171 INT102799 Negative_regulation of ESR2 1 0.35 0 0
172 INT245765 Binding of SOX9 1 0.31 0.87 0
173 INT312245 Positive_regulation of Localization of SOX9 1 0.10 0 0
174 INT185249 Positive_regulation of Gene_expression of Sox1 1 0.39 0 0
175 INT352010 Protein_catabolism of Sox9 1 0.22 0.07 0
176 INT277587 Localization of Mef2c 1 0.65 0.43 0
177 INT308349 Positive_regulation of Gene_expression of Sox9 1 0.40 0.69 0
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