GO:0001047

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Name core promoter binding
Categary Function
Go Slim No
Go Link GO:0001047
Unique Molecular Interactions 299
Total Molecular Interactions 441
Total Single Events 1870
Pain Genes Associated 31

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for core promoter binding. They are ordered first by their pain relevance and then by number of times they were reported for core promoter binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
2 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
3 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
4 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
5 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
6 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16
7 INT200307 Rest Negative_regulation of Rorb 1 0.00 0.1 1.03
8 INT117005 Sfpi1 Positive_regulation of Oprm1 1 0.52 0.56 0.94
9 INT200308 Binding of Rest and Rorb 1 0.00 0 0.87
10 INT200317 Rest Negative_regulation of Transcription of Oprm1 1 0.31 0 0.64
11 INT117007 Binding of Oprm1 and Sfpi1 1 0.50 0.07 0.63
12 INT54942 Rb1 Regulation of Gab1 1 0.02 0.39 0.59
13 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
14 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
15 INT164262 TGM7 Negative_regulation of E2F1 1 0.16 1.08 0.53
16 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
17 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
18 INT117006 Sfpi1 Negative_regulation of Oprm1 1 0.39 0.29 0.49
19 INT200321 Binding of Rest and Negative_regulation of Gene_expression of Oprm1 1 0.36 0.05 0.49
20 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
21 INT306828 Binding of E2F2 and E2F3 1 0.20 0.15 0.46
22 INT163040 E2f1 Positive_regulation of Transcription of Oprm1 1 0.00 0 0.46
23 INT306824 Binding of E2F1 and E2F2 1 0.15 0.15 0.46
24 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
25 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
26 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
27 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
28 INT200327 Oprm1 Negative_regulation of Gene_expression of Rest 1 0.31 0 0.41
29 INT200314 Oprm1 Regulation of Rest 1 0.20 0.1 0.39
30 INT200353 Rest Negative_regulation of Oprm1 1 0.31 0.1 0.39
31 INT200302 Rest Regulation of Rorb 1 0.00 0.07 0.38
32 INT85782 Rb1 Regulation of PRKG1 1 0.00 0.38 0.37
33 INT85778 Rb1 Regulation of Prkaca 1 0.00 0.38 0.36
34 INT85779 Rb1 Regulation of Prkcg 1 0.01 0.38 0.36
35 INT306830 E2F2 Regulation of C1orf61 1 0.02 0.48 0.36
36 INT200333 Binding of Rest and Sp1 1 0.24 0.07 0.35
37 INT200316 Sp1 Regulation of Gene_expression of Rest 1 0.31 0 0.35
38 INT306822 Binding of E2F2 and GOPC 1 0.05 0.53 0.35
39 INT200352 Binding of Rest and Rcor2 1 0.16 0.44 0.34
40 INT204080 HP Negative_regulation of Phosphorylation of Rb1 1 0.00 3.53 0.34
41 INT54943 Gab1 Regulation of Rb1 1 0.02 0.2 0.31
42 INT200351 Sp1 Positive_regulation of Gene_expression of Rest 1 0.34 0.07 0.3
43 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
44 INT242878 INS Negative_regulation of Gene_expression of SPI1 1 0.04 1.81 0.27
45 INT317773 Positive_regulation of GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
46 INT317775 GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
47 INT294514 Safb Positive_regulation of Localization of Hand1 1 0.08 0.38 0.25
48 INT317771 GSR Positive_regulation of HDAC1 1 0.10 0.69 0.25
49 INT317776 Positive_regulation of GSR Positive_regulation of HDAC1 1 0.10 0.69 0.25
50 INT200309 Positive_regulation of Binding of Rest and Sp3 1 0.41 0.88 0.24
51 INT256656 Binding of EP300 and HHIP 1 0.22 0 0.24
52 INT333892 TNF Positive_regulation of Gene_expression of HDAC1 1 0.09 0.46 0.23
53 INT97691 Binding of REST and HDAC9 1 0.26 0.09 0.23
54 INT97694 Ngf Negative_regulation of Gene_expression of REST 1 0.01 0.09 0.21
55 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19
56 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19
57 INT339336 Binding of NKX3-1 and TAC4 1 0.03 0.08 0.18
58 INT119264 Binding of RB1 and PPM1E 1 0.00 0.46 0.17
59 INT243772 Safb Negative_regulation of Gria1 1 0.23 0.84 0.17
60 INT119267 Binding of EP300 and PPM1E 1 0.01 0.46 0.17
61 INT221899 Rb1 Positive_regulation of Transcription of Ccl20 1 0.01 0.62 0.16
62 INT221908 Rb1 Positive_regulation of Transcription of TNIP2 1 0.01 0.62 0.16
63 INT104797 Smarce1 Positive_regulation of REST 1 0.01 0.24 0.15
64 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
65 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
66 INT255258 Binding of Rb1 and Tsp1 1 0.38 0.95 0.15
67 INT156833 Binding of MED1 and TRPV6 1 0.32 0 0.15
68 INT156837 Binding of CYP24A1 and MED1 1 0.47 0 0.15
69 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
70 INT310263 Rb1 Negative_regulation of Gene_expression of Tnf 1 0.07 0.97 0.15
71 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
72 INT302156 AKT1 Positive_regulation of E2F2 1 0.02 0.88 0.13
73 INT200338 Rest Positive_regulation of Gene_expression of Oprm1 1 0.36 0 0.13
74 INT200326 Hdac1 Negative_regulation of Lhcgr 1 0.03 0 0.12
75 INT325056 Binding of E2f1 and Ang 1 0.06 1.3 0.12
76 INT226907 Binding of E2f1 and Nfkb1 1 0.14 0.6 0.12
77 INT200318 Hdac1 Negative_regulation of Transcription of Lhcgr 1 0.03 0 0.12
78 INT200306 Hdac1 Negative_regulation of Rorb 1 0.00 0 0.12
79 INT319731 Ep300 Positive_regulation of Binding of Rela 1 0.01 0.37 0.12
80 INT200332 Binding of Rcor2 and Hdac1 1 0.15 0.3 0.12
81 INT317891 Binding of Akt1 and Mtf1 1 0.21 1.04 0.11
82 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11
83 INT242881 SPI1 Negative_regulation of Regulation of TLR2 1 0.04 1.13 0.11
84 INT317896 Binding of Mmp9 and Mtf1 1 0.36 1.04 0.11
85 INT317887 Binding of Mtf1 and Pik3r1 1 0.25 1.04 0.11
86 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11
87 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11
88 INT153637 Gene_expression of REST Positive_regulation of Gene_expression of Oprm1 1 0.03 0.08 0.1
89 INT294513 Safb Regulation of Pigr 1 0.16 0.12 0.1
90 INT153636 Binding of REST and Oprm1 1 0.02 0.09 0.09
91 INT238392 RB1 Regulation of E2F2 1 0.01 0.36 0.08
92 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
93 INT255256 Positive_regulation of Binding of Rb1 and Tsp1 1 0.50 0.48 0.08
94 INT238397 EID1 Regulation of E2F2 1 0.00 0.36 0.08
95 INT287880 Binding of CREB1 and EP300 1 0.01 0 0.08
96 INT196213 REST Regulation of Gene_expression of CACNA1A 1 0.46 0.08 0.08
97 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07
98 INT242880 Binding of SPI1 and TLR4 1 0.03 0.24 0.07
99 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07
100 INT189557 Binding of NOTCH1 and ROBO4 1 0.01 0.22 0.06
101 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
102 INT294519 Safb Positive_regulation of Gene_expression of Cd79a 1 0.34 0.4 0.06
103 INT76862 Dynll1 Positive_regulation of Rb1 1 0.37 0.1 0.06
104 INT257867 Negative_regulation of Eif4e Positive_regulation of Rb1 1 0.05 0.54 0.06
105 INT197617 Binding of S100a6 and Rb1 1 0.03 0 0.06
106 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06
107 INT298806 Binding of Hdac3 and Rb1 1 0.02 0.77 0.05
108 INT293494 Sfpi1 Regulation of Negative_regulation of Hsp90aa1 1 0.04 0.23 0.05
109 INT268676 Binding of HDAC1 and BCOR 1 0.01 1.31 0.04
110 INT333844 Binding of Ccna1 and E2f2 1 0.00 0.48 0.04
111 INT169962 Binding of Rb1 and E2f4 1 0.25 0.56 0.04
112 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
113 INT170328 Gene_expression of Ido1 Positive_regulation of Hmga2 1 0.01 0.13 0.04
114 INT349314 Binding of Notch1 and Notch3 1 0.11 0.67 0.04
115 INT225569 Binding of Ncoa6 and Ep300 1 0.18 0.63 0.04
116 INT333848 Binding of Ccna1 and Rb1 1 0.04 0.48 0.04
117 INT254282 Sfpi1 Positive_regulation of Binding of Pam16 1 0.02 0.23 0.03
118 INT197587 Ppt1 Positive_regulation of Rb1 1 0.18 0 0.03
119 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03
120 INT197593 Dlat Positive_regulation of Rb1 1 0.04 0 0.03
121 INT94157 CDCP1 Negative_regulation of RB1 1 0.02 0.92 0.03
122 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03
123 INT348592 Binding of HDAC1 and PPARG 1 0.23 0 0.03
124 INT254285 Sfpi1 Positive_regulation of Gene_expression of THPO 1 0.02 0.17 0.03
125 INT94159 Positive_regulation of CDK1 Negative_regulation of RB1 1 0.45 0.93 0.03
126 INT200311 Htt Positive_regulation of Rest 1 0.05 0.75 0.03
127 INT94158 CDK1 Negative_regulation of RB1 1 0.41 0.92 0.03
128 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03
129 INT242884 INS Regulation of SPI1 1 0.03 0.3 0.03
130 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0
131 INT238393 Binding of E2F2 and RB1 3 0.04 0.24 0
132 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0
133 INT319171 Binding of Cgn and Hdac1 1 0.00 0 0
134 INT280849 REST Negative_regulation of Gene_expression of Avp 1 0.09 0.09 0
135 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
136 INT225610 Ncoa6 Regulation of Rb1 1 0.03 0.21 0
137 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0
138 INT196948 Hmga2 Positive_regulation of Hdac1 1 0.36 0.23 0
139 INT294515 Safb Regulation of Phosphorylation of Hand1 1 0.08 0.07 0
140 INT294511 Safb Regulation of Sell 1 0.14 0 0
141 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
142 INT196208 REST Regulation of CACNA1A 1 0.46 0.06 0
143 INT225562 Binding of Srcs4 and Ep300 1 0.02 0 0
144 INT316648 Safb Positive_regulation of Car2 1 0.02 0 0
145 INT196954 Binding of Atp8a1 and E2f1 1 0.40 0.49 0
146 INT242876 Negative_regulation of Binding of SPI1 and TLR4 1 0.04 0.05 0
147 INT301244 Rb1 Regulation of Hbp1 1 0.03 0.75 0
148 INT337402 LEF1 Positive_regulation of E2F1 1 0.11 0 0
149 INT219409 CCNF Regulation of E2F2 1 0.22 0.11 0
150 INT196216 Binding of CACNA1A and REST 1 0.28 0 0
151 INT284296 Mir155 Regulation of Spi1 1 0.25 0.36 0
152 INT306827 Binding of E2F2 and NOLC1 1 0.07 0.05 0
153 INT333685 Binding of Trp53 and Hdac1 1 0.26 0.55 0
154 INT337270 E2F1 Positive_regulation of Transcription of THBS1 1 0.67 0.19 0
155 INT345505 E2f1 Positive_regulation of PMAIP1 1 0.18 0.62 0
156 INT334322 Binding of RB1 and TP53 1 0.34 2 0
157 INT337268 E2F1 Regulation of Transcription of THBS1 1 0.44 0 0
158 INT121179 Binding of Htt and Rest 1 0.07 0.45 0
159 INT182402 E2F2 Regulation of CCNB1 1 0.00 0.09 0
160 INT337274 E2F1 Regulation of THBS1 1 0.44 0 0
161 INT339096 Ezh2 Regulation of Rcc1 1 0.02 1.1 0
162 INT337269 Binding of E2F1 and Positive_regulation of Gene_expression of THBS1 1 0.45 0.21 0
163 INT273774 Binding of GPER and RB1 1 0.01 0.45 0
164 INT177262 Binding of MED1 and SV2A 1 0.23 0 0
165 INT284920 Binding of HDAC1 and NCOR1 1 0.03 0.13 0
166 INT287875 EP300 Negative_regulation of HDAC9 1 0.04 0.51 0
167 INT293492 Hsp90aa1 Regulation of Gene_expression of Sfpi1 1 0.04 0.1 0
168 INT291329 Binding of NOTCH1 and CERS1 1 0.06 1.42 0
169 INT356083 Binding of App and Notch1 1 0.02 0.2 0
170 INT305542 Binding of Rb1 and Trp53 1 0.00 0.9 0
171 INT232715 Binding of LAMB2 and SAFB 1 0.00 0.29 0
172 INT316649 Safb Positive_regulation of Localization of Car2 1 0.02 0 0
173 INT193949 Alph1 Positive_regulation of Notch1 1 0.01 0.08 0
174 INT294518 Safb Regulation of Gene_expression of Cd79a 1 0.22 0 0
175 INT169963 Positive_regulation of Binding of Rb1 and Rbl2 1 0.33 0.1 0
176 INT306825 Positive_regulation of Binding of E2F2 and RB1 1 0.04 0.05 0
177 INT196959 Hmga2 Positive_regulation of Localization of E2f1 1 0.54 0.24 0
178 INT177790 MTF1 Positive_regulation of NR2F1 1 0.10 0 0
179 INT172604 Binding of EP300 and TP53 1 0.00 0 0
180 INT350715 Sfpi1 Positive_regulation of Transcription of MIR424 1 0.09 0.25 0
181 INT284914 Binding of HDAC1 and NCK1 1 0.00 0.13 0
182 INT196958 Phosphorylation of Rb1 Positive_regulation of Localization of E2f1 1 0.45 0.44 0
183 INT169959 Binding of Rb1 and Rbl2 1 0.26 0.1 0
184 INT193950 Alph1 Positive_regulation of Positive_regulation of Notch1 1 0.01 0.07 0
185 INT336469 Binding of CTS and SAFB 1 0.09 0 0
186 INT311398 Positive_regulation of Celf1 Positive_regulation of Hdac1 1 0.12 0.19 0
187 INT182399 E2F2 Regulation of CDK1 1 0.00 0.09 0
188 INT337264 Binding of E2F1 and THBS1 1 0.47 0.78 0
189 INT333448 RB1 Positive_regulation of TFDP1 1 0.05 0 0
190 INT243107 Binding of Src and Ep300 1 0.06 0.17 0
191 INT330696 Phosphorylation of RB1 Positive_regulation of Gene_expression of E2F2 1 0.01 1 0
192 INT337273 E2F1 Regulation of Gene_expression of THBS1 1 0.60 0 0
193 INT177788 NR4A1 Positive_regulation of MTF1 1 0.08 0 0
194 INT172606 EP300 Positive_regulation of CREBBP 1 0.00 0.07 0
195 INT294517 Safb Regulation of Cd79a 1 0.13 0.54 0
196 INT196940 Positive_regulation of Hmga2 Positive_regulation of E2f1 1 0.50 0.47 0
197 INT196955 Binding of E2f1 and Rb1 1 0.36 1 0
198 INT217149 MIR20A Regulation of Gene_expression of E2F1 1 0.19 0.86 0
199 INT177785 Negative_regulation of MTF1 Negative_regulation of MT1F 1 0.03 0.16 0
200 INT330698 PCNA Regulation of RB1 1 0.00 0.3 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for core promoter binding. They are ordered first by their pain relevance and then by number of times they were reported in core promoter binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
2 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37
3 INT333909 Positive_regulation of Gene_expression of HDAC1 1 0.44 14.15 5.9
4 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
5 INT117004 Gene_expression of Sfpi1 21 0.75 15.95 5.29
6 INT97693 Gene_expression of REST 29 0.75 5.51 5.26
7 INT174189 Gene_expression of E2F2 19 0.49 12.58 4.71
8 INT2213 Regulation of EP300 10 0.54 4.72 4.5
9 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
10 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
11 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
12 INT200248 Gene_expression of Rest 1 0.66 1.25 3.7
13 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21
14 INT29929 Gene_expression of Rb1 20 0.69 5.81 3.1
15 INT34977 Gene_expression of Hmga2 11 0.76 12.39 3.07
16 INT199255 Binding of Rest 14 0.41 1.43 2.94
17 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
18 INT54938 Regulation of Rb1 6 0.44 4.41 2.69
19 INT58720 Negative_regulation of SAFB 4 0.50 0.19 2.69
20 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
21 INT306835 Regulation of E2F2 1 0.39 2.52 2.62
22 INT1540 Positive_regulation of SAFB 9 0.43 1.97 2.56
23 INT175703 Negative_regulation of E2F2 6 0.38 3.47 2.44
24 INT57970 Positive_regulation of Rb1 17 0.67 7.03 2.36
25 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31
26 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29
27 INT163283 Gene_expression of E2F1 21 0.71 3.77 2.26
28 INT26123 Regulation of Ep300 6 0.23 1.22 2.03
29 INT171514 Binding of EP300 13 0.32 4.32 2.01
30 INT26124 Negative_regulation of Ep300 5 0.37 1.25 1.94
31 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
32 INT117003 Binding of Sfpi1 5 0.47 5.04 1.74
33 INT294504 Gene_expression of Safb 9 0.41 0.97 1.72
34 INT172622 Localization of EP300 8 0.65 2.56 1.72
35 INT57971 Regulation of Rb1 5 0.41 2.36 1.66
36 INT153635 Positive_regulation of Gene_expression of REST 10 0.54 1.38 1.6
37 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57
38 INT28367 Positive_regulation of REST 10 0.54 2.07 1.52
39 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
40 INT182427 Binding of E2F2 7 0.23 2.78 1.49
41 INT165005 Binding of REST 26 0.43 2.81 1.39
42 INT333914 Transcription of HDAC1 1 0.34 3.04 1.37
43 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
44 INT169907 Gene_expression of Rb1 25 0.60 21.95 1.32
45 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
46 INT63905 Regulation of RB1 13 0.62 12.67 1.28
47 INT306868 Positive_regulation of Gene_expression of E2F1 6 0.46 1.01 1.28
48 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26
49 INT306857 Binding of E2F3 1 0.21 1.22 1.24
50 INT243771 Negative_regulation of Safb 7 0.26 0.77 1.23
51 INT41124 Negative_regulation of Rb1 11 0.44 3.17 1.22
52 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
53 INT70821 Positive_regulation of Ep300 4 0.25 1.47 1.2
54 INT110780 Localization of Notch1 2 0.06 0.47 1.19
55 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
56 INT118368 Positive_regulation of E2F1 10 0.69 0.8 1.13
57 INT260285 Gene_expression of E2F3 6 0.54 2.51 1.13
58 INT260447 Binding of HDAC1 8 0.23 4.47 1.12
59 INT126993 Binding of E2F1 5 0.44 1.39 1.12
60 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
61 INT238440 Negative_regulation of Binding of E2F2 3 0.27 1.09 1.07
62 INT238433 Negative_regulation of Gene_expression of E2F2 2 0.27 1.01 1.07
63 INT333907 Positive_regulation of HDAC1 4 0.32 3.07 1.03
64 INT117002 Negative_regulation of Sfpi1 16 0.58 9.72 1
65 INT167650 Binding of Ep300 1 0.09 0.14 1
66 INT34978 Negative_regulation of Gene_expression of Hmga2 2 0.42 1.53 0.95
67 INT174188 Positive_regulation of Gene_expression of RB1 9 0.45 6.22 0.94
68 INT306846 Negative_regulation of Binding of E2F3 1 0.24 0.65 0.94
69 INT306891 Negative_regulation of E2F3 1 0.25 0.65 0.94
70 INT190591 Positive_regulation of Rest 3 0.37 2.52 0.92
71 INT200255 Localization of Rest 1 0.68 0.14 0.86
72 INT306862 Regulation of Gene_expression of E2F2 1 0.17 0.19 0.85
73 INT306834 Positive_regulation of Gene_expression of E2F3 2 0.29 1 0.82
74 INT306867 Positive_regulation of Gene_expression of E2F2 1 0.31 0.59 0.82
75 INT169911 Phosphorylation of Rb1 35 0.73 18.58 0.79
76 INT27135 Gene_expression of SAFB 9 0.68 0.96 0.79
77 INT126990 Positive_regulation of Binding of E2F1 4 0.58 0 0.79
78 INT84726 Gene_expression of NKX3-1 4 0.75 2.1 0.75
79 INT284955 Localization of HDAC1 2 0.47 1.71 0.74
80 INT41123 Positive_regulation of Rb1 12 0.44 3.03 0.73
81 INT74097 Gene_expression of Ep300 6 0.52 1.89 0.73
82 INT242889 Binding of SPI1 15 0.36 7.37 0.69
83 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
84 INT86127 Positive_regulation of Safb 5 0.50 0.35 0.68
85 INT169931 Localization of Rb1 6 0.70 4.79 0.65
86 INT88987 Gene_expression of HMGA2 8 0.77 10.46 0.64
87 INT242903 Gene_expression of SPI1 5 0.13 9.68 0.63
88 INT283070 Localization of Safb 2 0.43 1.21 0.61
89 INT306839 Negative_regulation of Gene_expression of E2F1 2 0.39 0.24 0.61
90 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
91 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
92 INT200273 Negative_regulation of Rest 1 0.43 0.69 0.55
93 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
94 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
95 INT153634 Regulation of REST 4 0.48 1.42 0.54
96 INT62266 Phosphorylation of Rb1 4 0.71 2.68 0.54
97 INT118369 Regulation of E2F1 5 0.56 3.51 0.52
98 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51
99 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
100 INT163038 Binding of E2f1 2 0.44 0.08 0.5
101 INT181281 Localization of NKX3-1 1 0.12 0.3 0.5
102 INT177842 Negative_regulation of HDAC1 6 0.31 4.65 0.49
103 INT88170 Positive_regulation of HMGA2 2 0.69 2 0.48
104 INT93397 Negative_regulation of Phosphorylation of Rb1 1 0.51 0.32 0.48
105 INT163035 Gene_expression of E2f1 8 0.71 2.68 0.47
106 INT175702 Positive_regulation of E2F2 2 0.43 0.46 0.46
107 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
108 INT163037 Positive_regulation of Gene_expression of E2f1 1 0.11 0 0.44
109 INT163036 Positive_regulation of E2f1 1 0.11 0 0.44
110 INT84724 Negative_regulation of Gene_expression of NKX3-1 1 0.41 0.43 0.44
111 INT169952 Gene_expression of E2f1 12 0.64 4.35 0.43
112 INT194993 Binding of RB1 15 0.37 10.96 0.4
113 INT196916 Negative_regulation of Rb1 13 0.42 14.29 0.4
114 INT172626 Localization of E2F1 3 0.78 1.97 0.4
115 INT165006 Positive_regulation of Binding of REST 1 0.23 0.94 0.4
116 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39
117 INT41125 Positive_regulation of Localization of Rb1 2 0.38 0.78 0.39
118 INT41126 Localization of Rb1 2 0.61 0.78 0.39
119 INT147152 Negative_regulation of E2F1 6 0.56 0.89 0.38
120 INT181025 Localization of Sfpi1 3 0.80 4.96 0.38
121 INT233917 Gene_expression of MED1 2 0.20 0.17 0.38
122 INT196927 Binding of Hdac1 9 0.36 2.31 0.36
123 INT88167 Negative_regulation of Positive_regulation of HMGA2 1 0.41 0.16 0.35
124 INT200269 Negative_regulation of Transcription of Rest 1 0.31 0.08 0.35
125 INT200245 Transcription of Rest 1 0.51 0.08 0.35
126 INT187587 Binding of Ep300 11 0.35 2.37 0.34
127 INT80141 Negative_regulation of SPI1 6 0.08 5.44 0.34
128 INT84555 Negative_regulation of Spi1 6 0.42 0.71 0.34
129 INT196925 Positive_regulation of Gene_expression of Rb1 4 0.45 3.16 0.33
130 INT169918 Negative_regulation of Phosphorylation of Rb1 8 0.37 6.64 0.32
131 INT200270 Regulation of Rest 1 0.20 0.07 0.32
132 INT200256 Negative_regulation of Regulation of Rest 1 0.32 0.07 0.32
133 INT238429 Transcription of E2F2 3 0.45 0.55 0.31
134 INT181020 Positive_regulation of Gene_expression of Sfpi1 2 0.67 1.11 0.31
135 INT197599 Transcription of Rb1 4 0.63 0.87 0.3
136 INT258685 Regulation of Gene_expression of Notch1 2 0.40 1.45 0.3
137 INT88988 Positive_regulation of Gene_expression of HMGA2 1 0.69 4.05 0.29
138 INT181051 Transcription of Sfpi1 1 0.62 1.1 0.29
139 INT196917 Gene_expression of Hdac1 15 0.71 3.66 0.28
140 INT106734 Phosphorylation of MED1 4 0.74 1.65 0.28
141 INT196937 Positive_regulation of Hmga2 3 0.68 2.47 0.28
142 INT126991 Regulation of Binding of E2F1 1 0.23 0 0.28
143 INT294497 Positive_regulation of Localization of Safb 1 0.27 0.32 0.28
144 INT126992 Positive_regulation of Regulation of E2F1 1 0.58 0 0.28
145 INT185282 Localization of E2F2 3 0.47 1.92 0.25
146 INT306879 Negative_regulation of Transcription of E2F2 1 0.37 0.07 0.24
147 INT325492 Regulation of Ep300 1 0.04 0.29 0.24
148 INT356310 Regulation of Safb 1 0.06 0 0.24
149 INT242900 Regulation of SPI1 3 0.26 1.12 0.23
150 INT104789 Negative_regulation of REST 3 0.33 0.44 0.23
151 INT101308 Positive_regulation of Spi1 2 0.67 0.38 0.23
152 INT316049 Regulation of Regulation of Notch1 1 0.03 0.92 0.23
153 INT207163 Regulation of Gene_expression of Rb1 3 0.39 1.08 0.22
154 INT196920 Transcription of E2f1 4 0.68 2.65 0.21
155 INT130099 Negative_regulation of Positive_regulation of NOTCH1 4 0.43 2.56 0.21
156 INT181036 Positive_regulation of Sfpi1 3 0.49 0.96 0.21
157 INT196915 Positive_regulation of E2f2 3 0.01 2.82 0.2
158 INT212787 Negative_regulation of Binding of EP300 1 0.13 0.53 0.2
159 INT256666 Regulation of Gene_expression of EP300 1 0.14 0.07 0.2
160 INT256661 Regulation of Positive_regulation of EP300 1 0.23 0.07 0.2
161 INT196929 Positive_regulation of E2f1 10 0.66 4.29 0.19
162 INT193945 Binding of Notch1 7 0.15 1.28 0.19
163 INT325490 Positive_regulation of Ep300 1 0.03 0.22 0.19
164 INT130096 Positive_regulation of Positive_regulation of NOTCH1 2 0.50 1.15 0.18
165 INT101309 Gene_expression of Spi1 2 0.75 0.64 0.18
166 INT101307 Positive_regulation of Gene_expression of Spi1 1 0.67 0.28 0.18
167 INT293677 Transcription of RB1 1 0.62 0.8 0.18
168 INT339342 Binding of NKX3-1 1 0.04 0.08 0.18
169 INT106451 Regulation of Spi1 1 0.43 0 0.18
170 INT200275 Positive_regulation of Gene_expression of Rest 1 0.59 0.92 0.17
171 INT169930 Binding of Rb1 15 0.43 5.91 0.16
172 INT106730 Regulation of Phosphorylation of MED1 2 0.24 0.7 0.16
173 INT94168 Positive_regulation of Phosphorylation of RB1 12 0.60 6.6 0.15
174 INT216152 Binding of MTF1 2 0.23 0.41 0.15
175 INT298653 Positive_regulation of Binding of EP300 1 0.11 0.8 0.15
176 INT325053 Regulation of E2f1 1 0.19 2.02 0.15
177 INT197627 Localization of RB1 3 0.69 4.16 0.13
178 INT169928 Positive_regulation of Gene_expression of E2f1 3 0.48 1.29 0.13
179 INT177847 Positive_regulation of MTF1 2 0.29 0.48 0.13
180 INT181033 Regulation of Sfpi1 2 0.40 1.58 0.13
181 INT314724 Regulation of Localization of RB1 1 0.15 1.25 0.13
182 INT190563 Regulation of Binding of Rb1 1 0.08 0.7 0.13
183 INT338718 Positive_regulation of Localization of NOTCH1 1 0.04 0.6 0.13
184 INT106731 Negative_regulation of Phosphorylation of MED1 1 0.02 0.96 0.12
185 INT316643 Negative_regulation of Gene_expression of Safb 1 0.13 0.08 0.12
186 INT196934 Negative_regulation of Hdac1 4 0.39 1.41 0.11
187 INT169940 Positive_regulation of Localization of Rb1 2 0.61 1.74 0.11
188 INT317884 Transcription of Mtf1 1 0.63 1.02 0.11
189 INT331783 Regulation of Negative_regulation of Hdac1 1 0.04 0.98 0.11
190 INT200281 Negative_regulation of Negative_regulation of Rest 1 0.31 0.44 0.11
191 INT304667 Positive_regulation of SPI1 2 0.13 4.7 0.09
192 INT257732 Regulation of Positive_regulation of RB1 2 0.39 2.35 0.09
193 INT176587 Positive_regulation of Positive_regulation of SAFB 1 0.01 0.25 0.09
194 INT351182 Positive_regulation of Binding of SPI1 1 0.08 1.25 0.09
195 INT141999 Regulation of Gene_expression of NOTCH1 2 0.04 0.97 0.08
196 INT170298 Regulation of Gene_expression of Hmga2 1 0.01 0.48 0.08
197 INT196248 Localization of REST 1 0.66 0.15 0.08
198 INT156864 Positive_regulation of Phosphorylation of MED1 1 0.45 0 0.07
199 INT62267 Negative_regulation of Gene_expression of Rb1 1 0.12 0.82 0.07
200 INT163282 Negative_regulation of Phosphorylation of E2F1 1 0.35 0.33 0.07
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