GO:0001076

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Name RNA polymerase II transcription factor binding transcription factor activity
Categary Function
Go Slim No
Go Link GO:0001076
Unique Molecular Interactions 28
Total Molecular Interactions 34
Total Single Events 151
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II transcription factor binding transcription factor activity. They are ordered first by their pain relevance and then by number of times they were reported for RNA polymerase II transcription factor binding transcription factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
2 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
3 INT109065 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.00 0 0.58
4 INT93833 Binding of Fos and Srf 1 0.00 0 0.3
5 INT93832 Binding of Elk1 and Srf 1 0.00 0 0.29
6 INT255942 Elk1 Regulation of Binding of ATF2 1 0.07 0.12 0.22
7 INT255842 CREB1 Regulation of Binding of ATF2 1 0.03 0.12 0.22
8 INT255837 ATF2 Regulation of Binding of CREB1 1 0.03 0.12 0.22
9 INT255941 ATF2 Regulation of Transcription of Elk1 1 0.07 0.12 0.22
10 INT255835 ATF2 Regulation of Transcription of CREB1 1 0.03 0.12 0.22
11 INT255839 CREB1 Regulation of Transcription of ATF2 1 0.03 0.12 0.22
12 INT255937 ATF2 Regulation of Binding of Elk1 1 0.07 0.12 0.22
13 INT255939 Elk1 Regulation of Transcription of ATF2 1 0.07 0.12 0.22
14 INT216130 SRF Positive_regulation of Gene_expression of EGR1 1 0.49 0.32 0.07
15 INT216129 SRF Positive_regulation of Gene_expression of FOS 1 0.28 0.32 0.07
16 INT181814 Gsk3b Regulation of Gata4 1 0.06 0.37 0.05
17 INT319558 Positive_regulation of Creb1 Regulation of Srf 1 0.31 0.06 0.04
18 INT303393 Binding of Jag1 and Tceb2 1 0.03 0.29 0.04
19 INT319559 Creb1 Regulation of Srf 1 0.28 0.06 0.04
20 INT132849 Homer1 Regulation of Srf 1 0.01 0.15 0
21 INT225887 HGF Positive_regulation of ATF2 1 0.01 0 0
22 INT190632 Binding of Srf and Yy1 1 0.20 0.14 0
23 INT225590 Ncoa6 Regulation of Srf 1 0.08 0.21 0
24 INT274434 Binding of Gata4 and Zfpm2 1 0.12 0.56 0
25 INT326728 Sox10 Regulation of Twist2 1 0.45 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II transcription factor binding transcription factor activity. They are ordered first by their pain relevance and then by number of times they were reported in RNA polymerase II transcription factor binding transcription factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
2 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
3 INT89871 Gene_expression of Gata4 11 0.69 1.05 1.53
4 INT130207 Phosphorylation of ATF2 5 0.60 1.34 1.25
5 INT130209 Positive_regulation of Phosphorylation of ATF2 3 0.36 1.15 1.03
6 INT10448 Positive_regulation of Srf 3 0.47 0.89 1.03
7 INT135032 Negative_regulation of SRF 1 0.49 0 1.03
8 INT109069 Transcription of Gata4 4 0.64 0.52 1.01
9 INT109070 Positive_regulation of Transcription of Gata4 1 0.03 0 1.01
10 INT26531 Regulation of Srf 3 0.18 0.62 0.9
11 INT243611 Gene_expression of Twist2 5 0.67 2.85 0.86
12 INT69913 Binding of ATF2 6 0.13 0.83 0.84
13 INT45293 Transcription of Srf 2 0.47 0.79 0.76
14 INT69922 Positive_regulation of ATF2 3 0.05 1.28 0.74
15 INT45489 Gene_expression of SRF 5 0.77 3.29 0.71
16 INT89867 Negative_regulation of Gene_expression of Gata4 3 0.38 0.17 0.61
17 INT45292 Negative_regulation of Transcription of Srf 1 0.06 0.65 0.59
18 INT89868 Negative_regulation of Gata4 1 0.38 0 0.57
19 INT69915 Regulation of ATF2 2 0.34 0.81 0.42
20 INT255920 Gene_expression of ATF2 3 0.75 1.52 0.33
21 INT109058 Positive_regulation of Gene_expression of Gata4 2 0.29 0 0.33
22 INT18821 Positive_regulation of Gene_expression of Srf 2 0.35 0.63 0.31
23 INT7610 Localization of Srf 3 0.67 0.98 0.27
24 INT255901 Transcription of ATF2 1 0.25 0.12 0.22
25 INT243604 Localization of Twist2 1 0.65 0.54 0.2
26 INT243599 Positive_regulation of Localization of Twist2 1 0.43 0.54 0.2
27 INT89766 Binding of SRF 1 0.17 0.89 0.15
28 INT89767 Positive_regulation of Binding of SRF 1 0.23 0.89 0.15
29 INT69920 Negative_regulation of Binding of ATF2 1 0.06 0 0.1
30 INT69918 Negative_regulation of ATF2 1 0.06 0 0.1
31 INT22789 Binding of Srf 1 0.37 0.07 0.07
32 INT22790 Positive_regulation of Binding of Srf 1 0.50 0.07 0.07
33 INT190544 Transcription of Srf 1 0.19 0.43 0.06
34 INT190570 Localization of Srf 1 0.20 0.49 0.06
35 INT248540 Positive_regulation of Gata4 2 0.23 0.95 0.03
36 INT225411 Positive_regulation of Srf 1 0.05 0.27 0.03
37 INT268102 Transcription of SRF 1 0.53 0.85 0.03
38 INT225413 Binding of Srf 1 0.10 0.27 0.03
39 INT157800 Gene_expression of Srf 2 0.45 0.88 0
40 INT274404 Binding of Gata4 2 0.16 0.89 0
41 INT105753 Positive_regulation of Gene_expression of SRF 1 0.01 0.13 0
42 INT308517 Negative_regulation of Gene_expression of ATF2 1 0.07 0.13 0
43 INT326697 Negative_regulation of Twist2 1 0.35 0.23 0
44 INT308516 Positive_regulation of Gene_expression of ATF2 1 0.08 0.13 0
45 INT105752 Positive_regulation of SRF 1 0.01 0.13 0
46 INT268104 Negative_regulation of Gene_expression of SRF 1 0.38 0.16 0
47 INT326721 Regulation of Twist2 1 0.22 0.22 0
48 INT213446 Regulation of Gene_expression of SRF 1 0.22 0.71 0
49 INT181811 Localization of Gata4 1 0.54 0.3 0
50 INT225408 Negative_regulation of Srf 1 0.05 0.39 0
51 INT157799 Negative_regulation of Gene_expression of Srf 1 0.18 0.07 0
52 INT157794 Phosphorylation of Srf 1 0.26 0.07 0
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