GO:0001085

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Name RNA polymerase II transcription factor binding
Categary Function
Go Slim No
Go Link GO:0001085
Unique Molecular Interactions 375
Total Molecular Interactions 462
Total Single Events 3511
Pain Genes Associated 22

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II transcription factor binding. They are ordered first by their pain relevance and then by number of times they were reported for RNA polymerase II transcription factor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
3 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
4 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
5 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
6 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
7 INT117005 Sfpi1 Positive_regulation of Oprm1 1 0.52 0.56 0.94
8 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
9 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
10 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
11 INT266102 Binding of PITX2 and RS1 1 0.00 0.64 0.8
12 INT151807 Binding of NFATC1 and OPRM1 1 0.19 0 0.79
13 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
14 INT151808 NFATC1 Positive_regulation of Positive_regulation of OPRM1 1 0.20 0 0.76
15 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
16 INT117007 Binding of Oprm1 and Sfpi1 1 0.50 0.07 0.63
17 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
18 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58
19 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
20 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
21 INT335291 SLC15A4 Negative_regulation of NFATC1 1 0.01 0.45 0.51
22 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
23 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
24 INT117006 Sfpi1 Negative_regulation of Oprm1 1 0.39 0.29 0.49
25 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48
26 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
27 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
28 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
29 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
30 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38
31 INT319729 Binding of Rela and Crebbp 1 0.02 0.88 0.37
32 INT152453 Gsk3b Regulation of Nfkb1 1 0.02 1.68 0.36
33 INT66369 Pomc Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
34 INT321366 Gsk3b Regulation of Gene_expression of CYP8B1 1 0.01 0.21 0.33
35 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
36 INT182837 Binding of Creb1 and Crebbp 1 0.12 0.57 0.32
37 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
38 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
39 INT342810 Binding of Adarb1 and Gsk3b 1 0.00 0.36 0.3
40 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
41 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
42 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
43 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
44 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
45 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
46 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28
47 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
48 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
49 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
50 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
51 INT242878 INS Negative_regulation of Gene_expression of SPI1 1 0.04 1.81 0.27
52 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
53 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
54 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
55 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
56 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
57 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
58 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
59 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
60 INT118418 Gata1 Positive_regulation of Transcription of Tac2 1 0.61 0.77 0.25
61 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
62 INT118419 Binding of Gata1 and Tac2 1 0.31 0.7 0.24
63 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
64 INT141046 Binding of NFATC1 and ZNF404 1 0.01 0 0.24
65 INT141045 ZNF404 Negative_regulation of Transcription of NFATC1 1 0.01 0 0.24
66 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
67 INT141048 ZNF404 Negative_regulation of Binding of NFATC1 1 0.01 0 0.24
68 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
69 INT141041 ZNF404 Negative_regulation of NFATC1 1 0.01 0 0.23
70 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
71 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
72 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21
73 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
74 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
75 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
76 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19
77 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19
78 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
79 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
80 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19
81 INT261401 Binding of Gsk3b and ADHD1 1 0.00 1.62 0.18
82 INT119265 Binding of CREBBP and PPM1E 1 0.01 0.46 0.17
83 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
84 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
85 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
86 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
87 INT194811 Binding of Crebbp and Nfatc1 1 0.00 0.07 0.16
88 INT341818 Binding of PITX2 and Aia1 1 0.00 0.53 0.16
89 INT194826 Binding of CREB1 and Crebbp 1 0.02 0.07 0.16
90 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15
91 INT149092 PITX2 Positive_regulation of RFFL 1 0.00 1.51 0.15
92 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
93 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
94 INT326385 Mtdh Regulation of Gdnf 1 0.00 0.41 0.14
95 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
96 INT312893 Gsk3b Positive_regulation of Hdac6 1 0.07 0.65 0.13
97 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
98 INT263320 Gsk3b Regulation of Uts2r 1 0.02 0.68 0.13
99 INT263318 Akt1 Regulation of Gsk3b 1 0.02 0.75 0.13
100 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
101 INT354327 Gsk3b Positive_regulation of Gene_expression of Ide 1 0.17 0.33 0.13
102 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
103 INT287878 Binding of CREB1 and CREBBP 2 0.01 0.16 0.12
104 INT319726 Crebbp Positive_regulation of Binding of Rela 1 0.02 0.37 0.12
105 INT319731 Ep300 Positive_regulation of Binding of Rela 1 0.01 0.37 0.12
106 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
107 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11
108 INT242881 SPI1 Negative_regulation of Regulation of TLR2 1 0.04 1.13 0.11
109 INT268634 Ptpn2 Positive_regulation of Positive_regulation of Gsk3b 1 0.02 1.08 0.11
110 INT289768 Akt1 Regulation of Phosphorylation of Gsk3b 1 0.04 0.45 0.11
111 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11
112 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11
113 INT268626 Mpz Positive_regulation of Positive_regulation of Gsk3b 1 0.29 1.08 0.11
114 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
115 INT32546 Gsk3b Negative_regulation of Localization of Gnrh1 1 0.05 0 0.1
116 INT32547 Gsk3b Negative_regulation of Localization of LH 1 0.04 0 0.1
117 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
118 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
119 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
120 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
121 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
122 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09
123 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09
124 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
125 INT268627 Ptpn2 Positive_regulation of Gsk3b 1 0.02 1.7 0.08
126 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08
127 INT283721 Binding of Lpin1 and Id2 1 0.38 0.18 0.08
128 INT242880 Binding of SPI1 and TLR4 1 0.03 0.24 0.07
129 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
130 INT268630 Mpz Positive_regulation of Regulation of Gsk3b 1 0.18 0.57 0.07
131 INT354328 Gsk3b Regulation of Gs 1 0.16 0.84 0.07
132 INT354329 Gsk3b Regulation of Gene_expression of Gs 1 0.16 0.84 0.07
133 INT119268 CDKN1A Regulation of CREBBP 1 0.21 0.44 0.07
134 INT245296 Trp53 Regulation of Gadd45a 1 0.05 0.43 0.07
135 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07
136 INT118417 Gata1 Regulation of Gene_expression of Serpinb9g 1 0.17 0.12 0.06
137 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
138 INT221235 Akt1 Negative_regulation of Gsk3b 1 0.06 0.14 0.06
139 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
140 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
141 INT140291 ROS1 Positive_regulation of TP53 1 0.52 1.27 0.06
142 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06
143 INT265459 Phosphorylation of TP53 Positive_regulation of Localization of CASP9 1 0.17 1.16 0.05
144 INT352618 Tpt1 Regulation of Trp53 1 0.06 0.54 0.05
145 INT286768 Binding of Trp53 and Tusc2 1 0.07 1.1 0.05
146 INT352621 Gli1 Negative_regulation of Trp53 1 0.32 0.56 0.05
147 INT193966 AKT1 Negative_regulation of Gsk3b 1 0.05 0.75 0.05
148 INT193969 AKT1 Negative_regulation of Phosphorylation of Gsk3b 1 0.05 0.75 0.05
149 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05
150 INT265454 Phosphorylation of TP53 Positive_regulation of CASP9 1 0.17 1.16 0.05
151 INT293494 Sfpi1 Regulation of Negative_regulation of Hsp90aa1 1 0.04 0.23 0.05
152 INT181814 Gsk3b Regulation of Gata4 1 0.06 0.37 0.05
153 INT345181 Gpr87 Regulation of Trp53 1 0.01 0.42 0.05
154 INT193788 ITIH4 Regulation of Phosphorylation of TP53 1 0.07 0.45 0.05
155 INT193964 Mapk1 Negative_regulation of Gsk3b 1 0.00 0.74 0.05
156 INT352612 Trp53 Negative_regulation of Cd44 1 0.24 1.01 0.04
157 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04
158 INT172214 BAX Positive_regulation of TP53 1 0.09 0.37 0.04
159 INT329230 Negative_regulation of ATIC Positive_regulation of Trp53 1 0.00 0.58 0.04
160 INT329228 ATIC Positive_regulation of Trp53 1 0.01 0.58 0.04
161 INT352619 Bcl2l12 Negative_regulation of Trp53 1 0.27 0.94 0.04
162 INT352613 Binding of Trp53 and Bcl2l12 1 0.23 0.94 0.04
163 INT225569 Binding of Ncoa6 and Ep300 1 0.18 0.63 0.04
164 INT170457 RASGRP1 Regulation of TP53 1 0.02 0.58 0.04
165 INT201726 Mapk8 Positive_regulation of Positive_regulation of Trp53 1 0.00 0.41 0.04
166 INT290810 Gsk3b Regulation of Arntl 1 0.15 0 0.04
167 INT260267 Binding of TFAM and TP53 2 0.37 2.1 0.03
168 INT303092 Gsk3b Positive_regulation of NEUROG2 1 0.01 0.16 0.03
169 INT355036 CKAP4 Regulation of Positive_regulation of TP53 1 0.08 0.4 0.03
170 INT266903 Binding of Sod2 and Trp53 1 0.05 0 0.03
171 INT211873 TP53 Positive_regulation of Transcription of CD40 1 0.03 1.44 0.03
172 INT234625 TP53 Positive_regulation of IGFBP3 1 0.29 0.74 0.03
173 INT254282 Sfpi1 Positive_regulation of Binding of Pam16 1 0.02 0.23 0.03
174 INT226530 Binding of NFATC1 and Nfatc1 1 0.06 0.08 0.03
175 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
176 INT265464 CSPG4 Regulation of Gene_expression of TP53 1 0.09 0.23 0.03
177 INT290808 Gsk3b Positive_regulation of Arntl 1 0.25 0.17 0.03
178 INT234981 Binding of Dsg3 and Negative_regulation of Gsk3b 1 0.07 0.3 0.03
179 INT303083 Rorb Regulation of Gsk3b 1 0.00 0.52 0.03
180 INT314686 TP53 Regulation of Gene_expression of MDM2 1 0.21 0.96 0.03
181 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03
182 INT314677 TP53 Regulation of Positive_regulation of CDKN2A 1 0.27 0.97 0.03
183 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03
184 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03
185 INT254285 Sfpi1 Positive_regulation of Gene_expression of THPO 1 0.02 0.17 0.03
186 INT268629 Mpz Regulation of Phosphorylation of Gsk3b 1 0.26 1.05 0.03
187 INT314690 TP53 Regulation of Gene_expression of ZBTB7A 1 0.33 0.97 0.03
188 INT303079 Gsk3b Positive_regulation of Cebpg 1 0.08 0.16 0.03
189 INT242884 INS Regulation of SPI1 1 0.03 0.3 0.03
190 INT265906 IGF1 Regulation of Gsk3b 1 0.25 1.31 0.03
191 INT337811 Gene_expression of Gsk3b Positive_regulation of Phosphorylation of Akt1 1 0.37 0.37 0.03
192 INT211872 TP53 Positive_regulation of CD40 1 0.03 1.44 0.03
193 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0
194 INT339047 Binding of PITX2 and SNRNP70 1 0.00 0.52 0
195 INT340214 BGLAP Regulation of Gene_expression of NFATC1 1 0.02 0.76 0
196 INT352615 Binding of Mdm4 and Trp53 1 0.30 1.36 0
197 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0
198 INT315395 Regulation of Binding of IFNA1 and Tp53 1 0.00 0.46 0
199 INT304020 AR Regulation of TP53 1 0.24 1.11 0
200 INT315221 Tpt1 Regulation of Positive_regulation of Trp53 1 0.33 1.04 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II transcription factor binding. They are ordered first by their pain relevance and then by number of times they were reported in RNA polymerase II transcription factor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
2 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
3 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
4 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
5 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
6 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
7 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
8 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
9 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
10 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
11 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
12 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
13 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4
14 INT117004 Gene_expression of Sfpi1 21 0.75 15.95 5.29
15 INT60585 Regulation of TP53 59 0.59 54.55 5.21
16 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75
17 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
18 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
19 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
20 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27
21 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21
22 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83
23 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
24 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53
25 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07
26 INT8103 Binding of TP53 46 0.44 40.2 2.96
27 INT108793 Gene_expression of PITX2 12 0.75 3.91 2.89
28 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
29 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
30 INT55952 Transcription of TP53 16 0.61 12.14 2.36
31 INT26123 Regulation of Ep300 6 0.23 1.22 2.03
32 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
33 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
34 INT26124 Negative_regulation of Ep300 5 0.37 1.25 1.94
35 INT65855 Localization of TP53 18 0.76 17.08 1.89
36 INT204018 Localization of Gsk3b 27 0.71 13.67 1.87
37 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
38 INT117003 Binding of Sfpi1 5 0.47 5.04 1.74
39 INT118412 Gene_expression of Gata1 5 0.62 0.83 1.6
40 INT118413 Positive_regulation of Gene_expression of Gata1 3 0.40 0.68 1.56
41 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
42 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
43 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
44 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
45 INT172953 Binding of Trp53 33 0.37 20.76 1.41
46 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
47 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
48 INT145221 Binding of Tp53 10 0.37 8.59 1.37
49 INT319724 Binding of Crebbp 1 0.16 4.19 1.34
50 INT141054 Binding of NFATC1 14 0.40 3.65 1.22
51 INT70821 Positive_regulation of Ep300 4 0.25 1.47 1.2
52 INT174156 Localization of Trp53 16 0.72 13.52 1.18
53 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16
54 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
55 INT100154 Regulation of PITX2 5 0.60 0.48 1.15
56 INT134036 Regulation of Gsk3b 4 0.60 1.42 1.15
57 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
58 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11
59 INT208536 Positive_regulation of Positive_regulation of Gsk3b 6 0.30 4.83 1.11
60 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
61 INT117002 Negative_regulation of Sfpi1 16 0.58 9.72 1
62 INT167650 Binding of Ep300 1 0.09 0.14 1
63 INT116646 Regulation of Negative_regulation of Gsk3b 2 0.44 0.39 0.99
64 INT211548 Gene_expression of Lpin1 9 0.76 12.83 0.96
65 INT108795 Transcription of PITX2 1 0.69 0.46 0.96
66 INT117880 Negative_regulation of Crebbp 3 0.38 0.69 0.94
67 INT114922 Phosphorylation of Crebbp 2 0.21 0.92 0.94
68 INT261360 Binding of Gsk3b 5 0.36 2.85 0.9
69 INT141058 Gene_expression of NFATC1 8 0.56 8.21 0.89
70 INT138980 Binding of PITX2 15 0.47 10.34 0.88
71 INT199741 Gene_expression of DHX9 6 0.17 0.28 0.83
72 INT167285 Positive_regulation of Phosphorylation of Gsk3b 17 0.50 5.92 0.82
73 INT156945 Positive_regulation of Negative_regulation of Gsk3b 6 0.38 4.58 0.82
74 INT66365 Positive_regulation of Gene_expression of Gsk3b 2 0.07 0.95 0.81
75 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
76 INT116644 Phosphorylation of Gsk3b 4 0.61 0.68 0.78
77 INT204002 Negative_regulation of Gene_expression of Gsk3b 15 0.55 8.57 0.77
78 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
79 INT114956 Gene_expression of CREBBP 5 0.31 1.56 0.75
80 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
81 INT141057 Positive_regulation of NFATC1 5 0.57 1.95 0.74
82 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
83 INT74097 Gene_expression of Ep300 6 0.52 1.89 0.73
84 INT144995 Positive_regulation of Gata1 1 0.37 0.14 0.71
85 INT242889 Binding of SPI1 15 0.36 7.37 0.69
86 INT242137 Negative_regulation of Positive_regulation of Gsk3b 7 0.39 2.99 0.67
87 INT242903 Gene_expression of SPI1 5 0.13 9.68 0.63
88 INT114955 Positive_regulation of Gene_expression of CREBBP 2 0.23 0.24 0.61
89 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
90 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
91 INT204006 Negative_regulation of Localization of Gsk3b 6 0.40 1.66 0.6
92 INT230679 Positive_regulation of Binding of Gsk3b 3 0.42 1.42 0.58
93 INT182835 Phosphorylation of Crebbp 2 0.26 0.78 0.54
94 INT117879 Regulation of Crebbp 1 0.24 0 0.54
95 INT182836 Positive_regulation of Crebbp 2 0.21 0.76 0.53
96 INT208537 Regulation of Gene_expression of Gsk3b 4 0.36 2.15 0.52
97 INT141052 Transcription of NFATC1 5 0.44 1.34 0.49
98 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
99 INT203478 Gene_expression of Crebbp 3 0.46 2.15 0.44
100 INT288540 Negative_regulation of Binding of Gsk3b 4 0.53 2.12 0.43
101 INT208552 Negative_regulation of Negative_regulation of Gsk3b 3 0.31 1.8 0.43
102 INT235064 Regulation of Positive_regulation of Gsk3b 3 0.41 1.5 0.42
103 INT226449 Negative_regulation of NFATC1 4 0.25 1.28 0.41
104 INT319725 Positive_regulation of Binding of Crebbp 1 0.17 1.12 0.4
105 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
106 INT204012 Regulation of Negative_regulation of Gsk3b 4 0.42 4.51 0.39
107 INT208538 Regulation of Phosphorylation of Gsk3b 3 0.49 4.49 0.38
108 INT181025 Localization of Sfpi1 3 0.80 4.96 0.38
109 INT141051 Phosphorylation of NFATC1 4 0.52 0.25 0.36
110 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
111 INT66364 Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
112 INT187587 Binding of Ep300 11 0.35 2.37 0.34
113 INT80141 Negative_regulation of SPI1 6 0.08 5.44 0.34
114 INT84555 Negative_regulation of Spi1 6 0.42 0.71 0.34
115 INT141056 Negative_regulation of Binding of NFATC1 2 0.35 0 0.31
116 INT181020 Positive_regulation of Gene_expression of Sfpi1 2 0.67 1.11 0.31
117 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
118 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
119 INT181051 Transcription of Sfpi1 1 0.62 1.1 0.29
120 INT268620 Regulation of Localization of Gsk3b 3 0.35 2.12 0.28
121 INT166960 Positive_regulation of Negative_regulation of TP53 2 0.25 1.65 0.26
122 INT166727 Regulation of Gene_expression of PITX2 1 0.60 0.09 0.26
123 INT319719 Negative_regulation of Binding of Crebbp 1 0.14 0.51 0.26
124 INT314729 Regulation of Localization of TP53 1 0.30 2.5 0.25
125 INT345254 Positive_regulation of Localization of Gsk3b 2 0.01 0.91 0.24
126 INT325492 Regulation of Ep300 1 0.04 0.29 0.24
127 INT204021 Transcription of Gsk3b 8 0.57 2.75 0.23
128 INT179088 Positive_regulation of Regulation of Trp53 3 0.38 3.23 0.23
129 INT242900 Regulation of SPI1 3 0.26 1.12 0.23
130 INT101308 Positive_regulation of Spi1 2 0.67 0.38 0.23
131 INT221770 Positive_regulation of Phosphorylation of Crebbp 1 0.14 0.21 0.23
132 INT156886 Positive_regulation of Localization of TP53 1 0.48 0.87 0.23
133 INT268621 Positive_regulation of Localization of Gsk3b 4 0.40 1.54 0.22
134 INT283693 Transcription of Lpin1 1 0.67 1.31 0.22
135 INT116647 Positive_regulation of Phosphorylation of Gsk3b 1 0.37 0.18 0.22
136 INT181036 Positive_regulation of Sfpi1 3 0.49 0.96 0.21
137 INT141055 Regulation of NFATC1 2 0.20 0.65 0.19
138 INT141050 Regulation of Positive_regulation of NFATC1 1 0.51 0 0.19
139 INT149094 Positive_regulation of Gene_expression of PITX2 1 0.05 1.23 0.19
140 INT325490 Positive_regulation of Ep300 1 0.03 0.22 0.19
141 INT101309 Gene_expression of Spi1 2 0.75 0.64 0.18
142 INT101307 Positive_regulation of Gene_expression of Spi1 1 0.67 0.28 0.18
143 INT106451 Regulation of Spi1 1 0.43 0 0.18
144 INT333222 Gene_expression of Mtdh 1 0.01 1.44 0.17
145 INT300284 Regulation of Phosphorylation of Tp53 1 0.16 1.51 0.17
146 INT333226 Negative_regulation of Gene_expression of Mtdh 1 0.00 1.44 0.17
147 INT337078 Negative_regulation of Localization of Trp53 1 0.20 1.3 0.17
148 INT251938 Positive_regulation of Gene_expression of MEF2A 1 0.12 0.14 0.17
149 INT251939 Gene_expression of MEF2A 1 0.18 0.14 0.16
150 INT179086 Positive_regulation of Negative_regulation of Trp53 5 0.50 4.78 0.15
151 INT125081 Positive_regulation of Binding of TP53 2 0.46 1.2 0.15
152 INT207805 Negative_regulation of Phosphorylation of Trp53 2 0.18 0.98 0.15
153 INT286749 Regulation of Localization of Trp53 1 0.06 1.39 0.15
154 INT152666 Negative_regulation of CREBBP 2 0.06 0.52 0.14
155 INT220570 Transcription of Gata1 2 0.05 0.91 0.14
156 INT249108 Regulation of MEF2A 1 0.17 0.28 0.14
157 INT292224 Localization of NFATC1 3 0.15 0.45 0.13
158 INT181033 Regulation of Sfpi1 2 0.40 1.58 0.13
159 INT168244 Regulation of Transcription of Tp53 1 0.33 0.57 0.13
160 INT211536 Binding of Lpin1 2 0.46 1.06 0.12
161 INT319722 Positive_regulation of Crebbp 1 0.17 0.62 0.12
162 INT319723 Protein_catabolism of Crebbp 1 0.30 0.56 0.12
163 INT268617 Negative_regulation of Regulation of Gsk3b 3 0.28 1.84 0.11
164 INT319721 Gene_expression of Crebbp 2 0.23 0.76 0.11
165 INT294379 Phosphorylation of Mef2a 1 0.56 0 0.1
166 INT294371 Positive_regulation of Phosphorylation of Mef2a 1 0.42 0 0.1
167 INT309869 Regulation of Binding of Gsk3b 1 0.12 0.66 0.1
168 INT297456 Protein_catabolism of Tp53 1 0.11 0.72 0.1
169 INT282593 Gene_expression of KLF4 8 0.61 1.09 0.09
170 INT111139 Localization of Tp53 4 0.45 2.4 0.09
171 INT304667 Positive_regulation of SPI1 2 0.13 4.7 0.09
172 INT312871 Positive_regulation of Transcription of Gsk3b 2 0.29 0.15 0.09
173 INT351182 Positive_regulation of Binding of SPI1 1 0.08 1.25 0.09
174 INT171528 Binding of CREBBP 3 0.07 0.47 0.08
175 INT234926 Protein_catabolism of Gsk3b 2 0.58 1.33 0.08
176 INT234906 Positive_regulation of Protein_catabolism of Gsk3b 2 0.33 1.33 0.08
177 INT294324 Positive_regulation of Transcription of NFATC1 1 0.09 0 0.08
178 INT294351 Regulation of Transcription of NFATC1 1 0.08 0 0.08
179 INT294337 Positive_regulation of Localization of NFATC1 1 0.13 0 0.08
180 INT352605 Regulation of Negative_regulation of Trp53 1 0.45 0.72 0.07
181 INT290401 Gene_expression of Mef2a 1 0.64 1.81 0.07
182 INT283679 Positive_regulation of Lpin1 1 0.48 0.57 0.07
183 INT242888 Negative_regulation of Binding of SPI1 1 0.10 0.41 0.06
184 INT262962 Localization of PITX2 1 0.42 0.64 0.06
185 INT242892 Regulation of Binding of SPI1 1 0.08 0.37 0.06
186 INT171421 Regulation of Positive_regulation of TP53 1 0.48 0.45 0.05
187 INT283677 Localization of Lpin1 1 0.32 0.37 0.05
188 INT315213 Negative_regulation of Binding of Trp53 1 0.32 0.11 0.05
189 INT282606 Positive_regulation of Gene_expression of KLF4 2 0.54 0.8 0.04
190 INT311668 Regulation of Regulation of TP53 2 0.36 3.58 0.04
191 INT319060 Localization of Crebbp 2 0.73 0 0.04
192 INT211538 Negative_regulation of Lpin1 1 0.57 1.28 0.04
193 INT336062 Regulation of Localization of Gsk3b 1 0.03 0.48 0.04
194 INT305536 Positive_regulation of Binding of Trp53 1 0.35 0.32 0.04
195 INT356474 Negative_regulation of PITX2 1 0.03 0.07 0.04
196 INT226451 Positive_regulation of Gene_expression of NFATC1 1 0.37 2.45 0.04
197 INT294339 Negative_regulation of Gene_expression of NFATC1 3 0.25 1.49 0.03
198 INT217802 Regulation of Transcription of TP53 2 0.37 0.81 0.03
199 INT259061 Negative_regulation of Regulation of TP53 2 0.10 2.23 0.03
200 INT203460 Negative_regulation of Gene_expression of Crebbp 2 0.25 0.73 0.03
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