GO:0001103

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Name RNA polymerase II repressing transcription factor binding
Categary Function
Go Slim No
Go Link GO:0001103
Unique Molecular Interactions 54
Total Molecular Interactions 67
Total Single Events 290
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II repressing transcription factor binding. They are ordered first by their pain relevance and then by number of times they were reported for RNA polymerase II repressing transcription factor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
2 INT134970 Positive_regulation of Binding of OPRK1 and SP1 1 0.00 0 1.05
3 INT134969 Binding of OPRK1 and SP1 1 0.00 0 1.04
4 INT77254 Binding of gr and Sp1 1 0.04 0.4 0.9
5 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89
6 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88
7 INT101258 Gene_expression of Gata6 Negative_regulation of Positive_regulation of ALOX15 1 0.42 0.65 0.87
8 INT157539 Binding of SP1 and Regulation of Gene_expression of OPRM1 1 0.36 1.2 0.72
9 INT98956 Positive_regulation of Binding of NR5A2 and SP1 1 0.00 0 0.7
10 INT207542 Sp1 Regulation of Oprm1 1 0.15 0.06 0.7
11 INT98958 Binding of NR5A2 and SP1 1 0.00 0 0.7
12 INT207547 Sp1 Regulation of Qsox1 1 0.05 0.06 0.67
13 INT123416 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.60 0 0.63
14 INT98953 Positive_regulation of Binding of SP1 and CFHR4 1 0.00 0 0.62
15 INT98954 Binding of SP1 and CFHR4 1 0.00 0 0.61
16 INT89332 Binding of SP1 and SP3 1 0.30 0.76 0.39
17 INT167558 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.03 0.07 0.36
18 INT200333 Binding of Rest and Sp1 1 0.24 0.07 0.35
19 INT200316 Sp1 Regulation of Gene_expression of Rest 1 0.31 0 0.35
20 INT200351 Sp1 Positive_regulation of Gene_expression of Rest 1 0.34 0.07 0.3
21 INT96789 Binding of SP1 and NR2F2 1 0.24 0.27 0.27
22 INT96787 SP1 Positive_regulation of GDF15 1 0.08 0.27 0.27
23 INT125515 SP1 Regulation of GDF15 1 0.14 0.47 0.26
24 INT169837 Sp1 Positive_regulation of Gene_expression of Kcnq3 1 0.04 0.08 0.26
25 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26
26 INT169836 Sp1 Positive_regulation of Gene_expression of Kcnq2 1 0.05 0.08 0.26
27 INT260739 Mapk14 Regulation of Positive_regulation of Sp1 1 0.01 1.06 0.25
28 INT189196 RASGRP1 Positive_regulation of SP1 1 0.05 0.63 0.21
29 INT316064 Binding of RBPJ and Csl 1 0.16 0.33 0.2
30 INT136462 Negative_regulation of Ptgs1 Negative_regulation of Gene_expression of Sp1 1 0.01 0.65 0.19
31 INT253564 Binding of Lpl and Sp1 1 0.13 0.9 0.14
32 INT200315 Binding of Sp1 and Sp3 1 0.29 0 0.12
33 INT68802 Sp1 Regulation of Gene_expression of Pebp1 1 0.24 0 0.12
34 INT253572 Binding of Csnk2a2 and Sp1 1 0.17 0 0.11
35 INT171163 Creb1 Regulation of Sp1 1 0.03 0.62 0.1
36 INT194822 Negative_regulation of MAPK1 Negative_regulation of Binding of Sp1 1 0.04 0.05 0.1
37 INT253571 Positive_regulation of Binding of Lpl and Sp1 1 0.17 0.42 0.09
38 INT253579 Negative_regulation of Binding of Lpl and Sp1 1 0.15 0.42 0.09
39 INT313509 Binding of ALOX5 and SP1 1 0.07 1.51 0.08
40 INT253577 Csnk2a2 Positive_regulation of Phosphorylation of Sp1 1 0.17 0.37 0.06
41 INT339110 ERBB2 Positive_regulation of GATA6 1 0.31 0.67 0.06
42 INT295718 Binding of PTGER2 and Positive_regulation of Positive_regulation of SP1 1 0.02 0.58 0.04
43 INT314052 Binding of VEGFA and Sp1 1 0.02 1.25 0.03
44 INT253566 Sp1 Positive_regulation of Lpl 1 0.18 0 0.03
45 INT269944 Gata6 Regulation of Gene_expression of Foxj1 1 0.19 0 0
46 INT245820 Binding of Sp1 and Tfap2a 1 0.03 0.64 0
47 INT259095 Binding of RBBP8 and LMO4 1 0.15 0.73 0
48 INT217780 MIR181A1 Regulation of GATA6 1 0.17 0.7 0
49 INT215344 Binding of Sp1 and Vdac1 1 0.02 0.1 0
50 INT292143 Binding of HIVEP1 and SP1 1 0.01 0.33 0
51 INT245829 Binding of VEGFA and Sp1 1 0.04 0.65 0
52 INT292149 Binding of GTF2B and SP1 1 0.03 0.4 0
53 INT269956 Gata6 Regulation of Gene_expression of Scgb1a1 1 0.17 0 0
54 INT215341 Binding of Htt and Sp1 1 0.03 0.25 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II repressing transcription factor binding. They are ordered first by their pain relevance and then by number of times they were reported in RNA polymerase II repressing transcription factor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT41558 Localization of Sp1 9 0.48 0.56 14.9
2 INT24082 Negative_regulation of Sp1 13 0.40 1.19 13.11
3 INT48555 Binding of SP1 30 0.46 11.38 6.53
4 INT41604 Negative_regulation of Localization of Sp1 2 0.30 0.32 5.86
5 INT123411 Gene_expression of Sp1 15 0.69 4.2 3.79
6 INT41559 Positive_regulation of Sp1 7 0.45 2.65 3.24
7 INT123409 Binding of Sp1 20 0.39 3.18 3.15
8 INT103607 Binding of Sp1 7 0.42 1.26 2.92
9 INT93213 Phosphorylation of Sp1 5 0.67 0.93 2.84
10 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68
11 INT24902 Gene_expression of SP1 17 0.71 8.11 2.58
12 INT23998 Positive_regulation of Sp1 4 0.40 0.51 2.56
13 INT103609 Transcription of Sp1 1 0.11 0.97 2.42
14 INT103608 Negative_regulation of Binding of Sp1 4 0.35 0.69 2.1
15 INT41495 Regulation of Sp1 7 0.42 2.96 2.05
16 INT41557 Gene_expression of Sp1 5 0.68 1.17 2.04
17 INT24906 Negative_regulation of SP1 8 0.40 4.48 1.77
18 INT101252 Negative_regulation of Gene_expression of Gata6 1 0.51 1.3 1.74
19 INT101244 Regulation of Gata6 3 0.40 1.52 1.7
20 INT41605 Positive_regulation of Localization of Sp1 1 0.05 0 1.58
21 INT123414 Transcription of Sp1 5 0.48 2.2 1.38
22 INT94692 Positive_regulation of Gene_expression of Sp1 3 0.17 0.39 1.28
23 INT24000 Regulation of Sp1 2 0.22 1.25 1.27
24 INT48554 Positive_regulation of SP1 12 0.49 3.64 1.2
25 INT93216 Negative_regulation of Phosphorylation of Sp1 2 0.14 0.4 1.13
26 INT123408 Positive_regulation of Gene_expression of Sp1 2 0.62 0.9 0.96
27 INT123407 Negative_regulation of Binding of Sp1 6 0.47 0.72 0.93
28 INT200272 Localization of Sp1 3 0.57 0.06 0.93
29 INT101248 Negative_regulation of Gata6 1 0.37 0.83 0.85
30 INT101251 Negative_regulation of Positive_regulation of Gata6 1 0.38 0.83 0.85
31 INT101250 Positive_regulation of Gata6 1 0.41 0.83 0.84
32 INT123410 Negative_regulation of Gene_expression of Sp1 3 0.38 1.01 0.82
33 INT101245 Transcription of Gata6 2 0.47 0.85 0.82
34 INT98967 Localization of SP1 2 0.60 0.15 0.66
35 INT24905 Negative_regulation of Gene_expression of SP1 4 0.39 2.05 0.65
36 INT126899 Regulation of SP1 5 0.43 2.53 0.57
37 INT89334 Negative_regulation of Binding of SP1 2 0.47 1.05 0.5
38 INT126896 Positive_regulation of Protein_catabolism of SP1 1 0.13 0.99 0.44
39 INT126895 Protein_catabolism of SP1 3 0.96 3.59 0.38
40 INT98963 Positive_regulation of Binding of SP1 1 0.43 0 0.37
41 INT166959 Positive_regulation of Positive_regulation of SP1 3 0.46 2.23 0.35
42 INT136460 Negative_regulation of Sp1 2 0.30 0.99 0.3
43 INT93215 Positive_regulation of Phosphorylation of Sp1 1 0.11 0.09 0.27
44 INT253556 Phosphorylation of Sp1 6 0.44 2.93 0.24
45 INT136457 Negative_regulation of Negative_regulation of Sp1 1 0.30 0.65 0.2
46 INT253542 Positive_regulation of Phosphorylation of Sp1 1 0.27 1.16 0.2
47 INT178673 Positive_regulation of Gene_expression of SP1 1 0.08 0.14 0.16
48 INT173632 Transcription of SP1 7 0.41 1.42 0.09
49 INT322523 Regulation of Transcription of SP1 1 0.11 0.15 0.09
50 INT339183 Positive_regulation of GATA6 1 0.16 0.66 0.06
51 INT194474 Positive_regulation of Binding of Sp1 1 0.03 0.6 0.04
52 INT194476 Regulation of Binding of Sp1 1 0.02 0.6 0.04
53 INT173623 Positive_regulation of Transcription of SP1 3 0.30 0.95 0
54 INT173637 Negative_regulation of Positive_regulation of SP1 1 0.05 0.27 0
55 INT217818 Gene_expression of GATA6 1 0.17 1.07 0
56 INT136453 Protein_catabolism of Sp1 1 0.70 0.15 0
57 INT292205 Phosphorylation of SP1 1 0.21 0.07 0
58 INT258553 Binding of RBPJ 1 0.11 1.06 0
59 INT328768 Positive_regulation of Gene_expression of Gata6 1 0.19 0.61 0
60 INT136455 Positive_regulation of Protein_catabolism of Sp1 1 0.49 0.15 0
61 INT78107 Regulation of Positive_regulation of SP1 1 0.32 0.1 0
62 INT339154 Negative_regulation of GATA6 1 0.14 0.86 0
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