GO:0001104

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Name RNA polymerase II transcription cofactor activity
Categary Function
Go Slim No
Go Link GO:0001104
Unique Molecular Interactions 19
Total Molecular Interactions 28
Total Single Events 167
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II transcription cofactor activity. They are ordered first by their pain relevance and then by number of times they were reported for RNA polymerase II transcription cofactor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86073 Med15 Regulation of Calca 1 0.49 0.2 1.03
2 INT156833 Binding of MED1 and TRPV6 1 0.32 0 0.15
3 INT156837 Binding of CYP24A1 and MED1 1 0.47 0 0.15
4 INT188007 NLRP3 Regulation of Binding of TP53BP1 1 0.28 0.62 0.08
5 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
6 INT188006 NLRP3 Regulation of Gene_expression of TP53BP1 1 0.28 0.36 0.04
7 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
8 INT188005 NLRP3 Regulation of TP53BP1 1 0.34 0.3 0.04
9 INT225027 Binding of TAPBP and TRERF1 1 0.33 0 0.04
10 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
11 INT204325 Binding of PPARGC1A and SIRT1 1 0.39 0.19 0
12 INT177262 Binding of MED1 and SV2A 1 0.23 0 0
13 INT204322 Binding of ADIPOQ and Positive_regulation of Gene_expression of PPARGC1A 1 0.30 0.07 0
14 INT204326 SIRT1 Positive_regulation of PPARGC1A 1 0.51 0.19 0
15 INT225481 Binding of Med1 and Acp5 1 0.16 0 0
16 INT177286 Binding of CXADR and MED1 1 0.27 0 0
17 INT225541 Binding of Med1 and Tpr 1 0.00 0.07 0
18 INT177280 Binding of MED1 and FAUP1 1 0.01 0 0
19 INT204319 SIRT1 Regulation of Gene_expression of PPARGC1A 1 0.50 0.12 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II transcription cofactor activity. They are ordered first by their pain relevance and then by number of times they were reported in RNA polymerase II transcription cofactor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86071 Negative_regulation of Med15 3 0.43 1.19 3.38
2 INT86072 Binding of Med15 1 0.47 0.23 0.9
3 INT93879 Positive_regulation of TRERF1 2 0.61 2.09 0.64
4 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39
5 INT233917 Gene_expression of MED1 2 0.20 0.17 0.38
6 INT188016 Gene_expression of TP53BP1 6 0.64 5.54 0.35
7 INT71036 Negative_regulation of TRERF1 1 0.00 0.47 0.3
8 INT106734 Phosphorylation of MED1 4 0.74 1.65 0.28
9 INT244618 Regulation of TRERF1 2 0.07 1.43 0.28
10 INT188021 Positive_regulation of TP53BP1 3 0.48 1.33 0.25
11 INT204348 Gene_expression of PPARGC1A 10 0.75 2.73 0.19
12 INT188019 Negative_regulation of TP53BP1 1 0.48 1.42 0.18
13 INT106730 Regulation of Phosphorylation of MED1 2 0.24 0.7 0.16
14 INT106731 Negative_regulation of Phosphorylation of MED1 1 0.02 0.96 0.12
15 INT188013 Phosphorylation of TP53BP1 1 0.78 1.81 0.09
16 INT225029 Gene_expression of TRERF1 3 0.53 1.62 0.08
17 INT188017 Binding of TP53BP1 1 0.46 1.28 0.08
18 INT204332 Positive_regulation of PPARGC1A 7 0.67 1.42 0.07
19 INT156864 Positive_regulation of Phosphorylation of MED1 1 0.45 0 0.07
20 INT188010 Positive_regulation of Gene_expression of TP53BP1 1 0.48 0.43 0.07
21 INT188020 Localization of TP53BP1 1 0.71 0.36 0.06
22 INT188008 Regulation of TP53BP1 4 0.37 1.1 0.04
23 INT204372 Transcription of PPARGC1A 3 0.67 0.28 0
24 INT307189 Localization of Med1 3 0.53 0.32 0
25 INT225400 Positive_regulation of Gene_expression of Med1 2 0.35 0.82 0
26 INT204346 Positive_regulation of Transcription of PPARGC1A 2 0.49 0.28 0
27 INT225358 Negative_regulation of Gene_expression of Med1 2 0.30 1.16 0
28 INT188014 Negative_regulation of Phosphorylation of TP53BP1 1 0.40 0.68 0
29 INT177336 Positive_regulation of Binding of MED1 1 0.24 0 0
30 INT307197 Negative_regulation of Med1 1 0.30 0.7 0
31 INT188009 Regulation of Regulation of TP53BP1 1 0.37 0.07 0
32 INT307188 Transcription of Med1 1 0.48 0.7 0
33 INT204350 Negative_regulation of Transcription of PPARGC1A 1 0.41 0.1 0
34 INT204333 Regulation of PPARGC1A 1 0.26 0.34 0
35 INT188012 Regulation of Binding of TP53BP1 1 0.58 0.14 0
36 INT225389 Regulation of Binding of Med1 1 0.17 0.07 0
37 INT177320 Binding of MED1 1 0.25 0 0
38 INT225457 Binding of Med1 1 0.35 0.28 0
39 INT204357 Positive_regulation of Positive_regulation of PPARGC1A 1 0.49 0.07 0
40 INT204347 Positive_regulation of Negative_regulation of PPARGC1A 1 0.49 0 0
41 INT204369 Negative_regulation of Positive_regulation of PPARGC1A 1 0.41 0.07 0
42 INT341851 Positive_regulation of MED1 1 0.01 0.5 0
43 INT225028 Binding of TRERF1 1 0.29 0 0
44 INT204366 Positive_regulation of Gene_expression of PPARGC1A 1 0.67 1.44 0
45 INT334482 Regulation of Gene_expression of Med1 1 0.17 0.1 0
46 INT204337 Regulation of Gene_expression of PPARGC1A 1 0.44 0.48 0
47 INT204339 Binding of PPARGC1A 1 0.35 0.19 0
48 INT204329 Positive_regulation of Regulation of PPARGC1A 1 0.45 0.07 0
49 INT204341 Negative_regulation of Gene_expression of PPARGC1A 1 0.41 0 0
50 INT188015 Negative_regulation of Localization of TP53BP1 1 0.35 0.16 0
51 INT204351 Negative_regulation of PPARGC1A 1 0.42 0.25 0
52 INT334481 Negative_regulation of Localization of Med1 1 0.16 0.09 0
53 INT188011 Negative_regulation of Gene_expression of TP53BP1 1 0.40 0.78 0
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