GO:0001159

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Name core promoter proximal region DNA binding
Categary Function
Go Slim No
Go Link GO:0001159
Unique Molecular Interactions 22
Total Molecular Interactions 29
Total Single Events 93
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for core promoter proximal region DNA binding. They are ordered first by their pain relevance and then by number of times they were reported for core promoter proximal region DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
2 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
3 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
4 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
5 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
6 INT70661 Binding of Hrasls and Nkx2-2 1 0.02 0 0.24
7 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19
8 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19
9 INT319731 Ep300 Positive_regulation of Binding of Rela 1 0.01 0.37 0.12
10 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11
11 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11
12 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11
13 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06
14 INT225569 Binding of Ncoa6 and Ep300 1 0.18 0.63 0.04
15 INT225562 Binding of Srcs4 and Ep300 1 0.02 0 0
16 INT243107 Binding of Src and Ep300 1 0.06 0.17 0
17 INT225619 Binding of TARBP2 and Ep300 1 0.02 0 0
18 INT240011 Ass1 Positive_regulation of Gene_expression of Nkx2-2 1 0.00 0 0
19 INT243111 Binding of Crebbp and Ep300 1 0.16 0.17 0
20 INT225543 Binding of D0Nrs1 and Ep300 1 0.01 0 0
21 INT225563 Binding of Tpr and Ep300 1 0.00 0 0
22 INT225622 Binding of STL and Ep300 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for core promoter proximal region DNA binding. They are ordered first by their pain relevance and then by number of times they were reported in core promoter proximal region DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48840 Gene_expression of Nkx2-2 8 0.23 1.55 5.44
2 INT15257 Positive_regulation of Nkx2-2 10 0.21 1.75 4.2
3 INT51180 Regulation of Nkx2-2 5 0.26 2.16 4.14
4 INT8600 Binding of Nkx2-2 6 0.10 0.87 3.82
5 INT26123 Regulation of Ep300 6 0.23 1.22 2.03
6 INT26124 Negative_regulation of Ep300 5 0.37 1.25 1.94
7 INT112845 Negative_regulation of Binding of Nkx2-2 2 0.12 0.14 1.47
8 INT132081 Regulation of Gene_expression of Nkx2-2 2 0.10 0.24 1.43
9 INT70821 Positive_regulation of Ep300 4 0.25 1.47 1.2
10 INT167650 Binding of Ep300 1 0.09 0.14 1
11 INT138396 Transcription of Nkx2-2 1 0.26 0.05 0.75
12 INT138395 Positive_regulation of Transcription of Nkx2-2 1 0.19 0.05 0.75
13 INT74097 Gene_expression of Ep300 6 0.52 1.89 0.73
14 INT48503 Positive_regulation of Positive_regulation of Nkx2-2 1 0.15 0 0.42
15 INT187587 Binding of Ep300 11 0.35 2.37 0.34
16 INT122619 Gene_expression of Nkx2-2 6 0.36 0.15 0.31
17 INT208497 Localization of Nkx2-2 1 0.01 0 0.26
18 INT325492 Regulation of Ep300 1 0.04 0.29 0.24
19 INT325490 Positive_regulation of Ep300 1 0.03 0.22 0.19
20 INT122620 Negative_regulation of Gene_expression of Nkx2-2 1 0.20 0 0.04
21 INT235154 Transcription of Ep300 2 0.24 1.38 0
22 INT143655 Transcription of Nkx2-2 1 0.58 0 0
23 INT143654 Positive_regulation of Transcription of Nkx2-2 1 0.56 0 0
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