GO:0001191

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Name RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
Categary Function
Go Slim No
Go Link GO:0001191
Unique Molecular Interactions 31
Total Molecular Interactions 49
Total Single Events 133
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription. They are ordered first by their pain relevance and then by number of times they were reported for RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
2 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
3 INT266102 Binding of PITX2 and RS1 1 0.00 0.64 0.8
4 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48
5 INT319729 Binding of Rela and Crebbp 1 0.02 0.88 0.37
6 INT182837 Binding of Creb1 and Crebbp 1 0.12 0.57 0.32
7 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19
8 INT119265 Binding of CREBBP and PPM1E 1 0.01 0.46 0.17
9 INT194811 Binding of Crebbp and Nfatc1 1 0.00 0.07 0.16
10 INT341818 Binding of PITX2 and Aia1 1 0.00 0.53 0.16
11 INT194826 Binding of CREB1 and Crebbp 1 0.02 0.07 0.16
12 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15
13 INT149092 PITX2 Positive_regulation of RFFL 1 0.00 1.51 0.15
14 INT287878 Binding of CREB1 and CREBBP 2 0.01 0.16 0.12
15 INT319726 Crebbp Positive_regulation of Binding of Rela 1 0.02 0.37 0.12
16 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11
17 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11
18 INT119268 CDKN1A Regulation of CREBBP 1 0.21 0.44 0.07
19 INT339047 Binding of PITX2 and SNRNP70 1 0.00 0.52 0
20 INT243106 Binding of Crebbp and Src 1 0.05 0.52 0
21 INT180028 Gopc Regulation of Bhlhe41 1 0.12 1.17 0
22 INT339043 SNRNP70 Regulation of PITX2 1 0.00 1.42 0
23 INT287882 Binding of CREBBP and HNF4A 1 0.01 0.85 0
24 INT250557 Binding of PITX2 and CHDH 1 0.00 2.83 0
25 INT172606 EP300 Positive_regulation of CREBBP 1 0.00 0.07 0
26 INT235165 Atxn3 Regulation of Transcription of Crebbp 1 0.02 0.3 0
27 INT339044 Binding of PITX2 and SUGT1 1 0.00 2.25 0
28 INT354309 Binding of MYC and PITX2 1 0.01 0.51 0
29 INT339049 Binding of PITX2 and RENBP 1 0.00 0.27 0
30 INT332963 Atp6v1e1 Negative_regulation of Binding of Crebbp 1 0.08 0 0
31 INT243111 Binding of Crebbp and Ep300 1 0.16 0.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription. They are ordered first by their pain relevance and then by number of times they were reported in RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108793 Gene_expression of PITX2 12 0.75 3.91 2.89
2 INT319724 Binding of Crebbp 1 0.16 4.19 1.34
3 INT100154 Regulation of PITX2 5 0.60 0.48 1.15
4 INT108795 Transcription of PITX2 1 0.69 0.46 0.96
5 INT117880 Negative_regulation of Crebbp 3 0.38 0.69 0.94
6 INT114922 Phosphorylation of Crebbp 2 0.21 0.92 0.94
7 INT138980 Binding of PITX2 15 0.47 10.34 0.88
8 INT149817 Gene_expression of Bhlhe41 2 0.43 2.47 0.81
9 INT114956 Gene_expression of CREBBP 5 0.31 1.56 0.75
10 INT149819 Regulation of Gene_expression of Bhlhe41 1 0.29 0 0.7
11 INT149804 Regulation of Bhlhe41 1 0.29 0 0.69
12 INT114955 Positive_regulation of Gene_expression of CREBBP 2 0.23 0.24 0.61
13 INT182835 Phosphorylation of Crebbp 2 0.26 0.78 0.54
14 INT117879 Regulation of Crebbp 1 0.24 0 0.54
15 INT182836 Positive_regulation of Crebbp 2 0.21 0.76 0.53
16 INT203478 Gene_expression of Crebbp 3 0.46 2.15 0.44
17 INT319725 Positive_regulation of Binding of Crebbp 1 0.17 1.12 0.4
18 INT166727 Regulation of Gene_expression of PITX2 1 0.60 0.09 0.26
19 INT319719 Negative_regulation of Binding of Crebbp 1 0.14 0.51 0.26
20 INT221770 Positive_regulation of Phosphorylation of Crebbp 1 0.14 0.21 0.23
21 INT149094 Positive_regulation of Gene_expression of PITX2 1 0.05 1.23 0.19
22 INT152666 Negative_regulation of CREBBP 2 0.06 0.52 0.14
23 INT319722 Positive_regulation of Crebbp 1 0.17 0.62 0.12
24 INT319723 Protein_catabolism of Crebbp 1 0.30 0.56 0.12
25 INT319721 Gene_expression of Crebbp 2 0.23 0.76 0.11
26 INT171528 Binding of CREBBP 3 0.07 0.47 0.08
27 INT262962 Localization of PITX2 1 0.42 0.64 0.06
28 INT180026 Positive_regulation of Bhlhe41 1 0.35 0.79 0.05
29 INT319060 Localization of Crebbp 2 0.73 0 0.04
30 INT356474 Negative_regulation of PITX2 1 0.03 0.07 0.04
31 INT203460 Negative_regulation of Gene_expression of Crebbp 2 0.25 0.73 0.03
32 INT243077 Regulation of Crebbp 1 0.27 0.13 0.03
33 INT203462 Negative_regulation of Crebbp 1 0.02 0.62 0.03
34 INT243085 Positive_regulation of Gene_expression of Crebbp 1 0.30 0.14 0.03
35 INT187585 Binding of Crebbp 6 0.36 0.11 0
36 INT250574 Positive_regulation of PITX2 2 0.02 1.79 0
37 INT172620 Localization of CREBBP 2 0.09 0.06 0
38 INT337420 Negative_regulation of Localization of Crebbp 1 0.41 0 0
39 INT340511 Localization of Crebbp 1 0.26 0 0
40 INT337421 Negative_regulation of Binding of Crebbp 1 0.41 0 0
41 INT276802 Negative_regulation of Gene_expression of CREBBP 1 0.03 0 0
42 INT340512 Positive_regulation of Gene_expression of Crebbp 1 0.17 0 0
43 INT235158 Transcription of Crebbp 1 0.05 0.29 0
44 INT332952 Positive_regulation of Binding of Crebbp 1 0.35 0 0
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