GO:0001504

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Name neurotransmitter uptake
Categary Process
Go Slim No
Go Link GO:0001504
Unique Molecular Interactions 40
Total Molecular Interactions 49
Total Single Events 467
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for neurotransmitter uptake. They are ordered first by their pain relevance and then by number of times they were reported for neurotransmitter uptake. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
2 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
3 INT250248 Binding of AQP4 and SLC1A3 1 0.11 1.55 0.77
4 INT128275 Slc17a7 Positive_regulation of Transcription of Slc17a6 1 0.39 0.27 0.63
5 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55
6 INT56733 Ddc Positive_regulation of Localization of GLUL 1 0.00 0 0.54
7 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52
8 INT250251 Binding of SLC1A2 and SLC1A3 1 0.09 1.12 0.43
9 INT250254 Binding of SLC1A3 and GOPC 1 0.02 0.44 0.35
10 INT268110 PRKCA Positive_regulation of Phosphorylation of SNAP25 1 0.32 0.11 0.35
11 INT333927 GLUL Positive_regulation of HSPA5 1 0.17 0.78 0.24
12 INT305504 Slc17a6 Positive_regulation of Ex 1 0.05 0.67 0.22
13 INT305505 Negative_regulation of Binding of Igfals and Slc17a6 1 0.16 1.12 0.21
14 INT305510 Binding of Igfals and Slc17a6 1 0.14 1.11 0.21
15 INT94890 MBTPS1 Positive_regulation of SNAP25 1 0.16 0.39 0.2
16 INT305508 Binding of Sod1 and Slc17a6 1 0.03 1.1 0.2
17 INT305511 Negative_regulation of Binding of Sod1 and Slc17a6 1 0.03 1.1 0.2
18 INT6697 Binding of GLUL and Positive_regulation of Positive_regulation of ADRA1D 1 0.23 0.16 0.19
19 INT250241 SLC1A3 Positive_regulation of AQP4 1 0.13 0.21 0.16
20 INT261521 Binding of ADCY1 and GLUL 1 0.01 0.09 0.15
21 INT333930 GLUL Positive_regulation of HRASLS 1 0.01 0.43 0.14
22 INT305506 Binding of Pgk1 and Slc17a6 1 0.04 0.31 0.11
23 INT251231 Binding of Syp and Slc17a6 1 0.04 0 0.08
24 INT305503 Binding of Nr5a1 and Slc17a6 1 0.08 0.37 0.08
25 INT251232 Slc17a6 Positive_regulation of Tgfb1 1 0.03 0 0.08
26 INT250249 Binding of SLC1A2 and Positive_regulation of SLC1A3 1 0.12 0.69 0.08
27 INT250244 Binding of AQP4 and Positive_regulation of SLC1A3 1 0.14 0.69 0.08
28 INT227593 Gnaq Negative_regulation of GLUL 1 0.01 0 0.06
29 INT227562 GNAI1 Negative_regulation of GLUL 1 0.01 0 0.06
30 INT250245 Binding of FCGR3A and SLC1A3 1 0.00 0.18 0.05
31 INT268111 Binding of MARCKS and SNAP25 1 0.09 0 0.05
32 INT227567 FOXI2 Positive_regulation of GLUL 1 0.00 0 0.03
33 INT227563 BRI3 Positive_regulation of GLUL 1 0.04 0 0.03
34 INT314395 Binding of Gpsm2 and Slc17a6 1 0.20 0 0
35 INT314399 Binding of Slc17a7 and Slc17a6 1 0.14 0 0
36 INT130533 BACE1 Regulation of SNAP25 1 0.27 0.18 0
37 INT130532 BACE2 Regulation of SNAP25 1 0.12 0.18 0
38 INT314396 Binding of Ptpn6 and Slc17a6 1 0.05 0 0
39 INT196209 Binding of REST and SNAP25 1 0.25 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for neurotransmitter uptake. They are ordered first by their pain relevance and then by number of times they were reported in neurotransmitter uptake. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT107928 Gene_expression of Slc17a6 34 0.76 3.76 16.64
2 INT139935 Gene_expression of Slc17a6 36 0.78 8.43 10.61
3 INT120335 Gene_expression of SNAP25 24 0.65 9.44 5.83
4 INT165460 Gene_expression of SLC1A3 15 0.75 7.19 5.43
5 INT139933 Negative_regulation of Slc17a6 3 0.59 10.25 5.43
6 INT120339 Phosphorylation of SNAP25 5 0.51 2.97 5.3
7 INT107586 Transcription of Slc17a6 6 0.61 0.79 3.68
8 INT180250 Positive_regulation of GLUL 23 0.29 7.57 3.23
9 INT120334 Negative_regulation of Phosphorylation of SNAP25 4 0.37 1.71 3.21
10 INT108728 Regulation of ATP1A2 4 0.45 3.65 3.04
11 INT186507 Localization of ATP1A2 2 0.74 3.35 3.04
12 INT106919 Regulation of Slc17a6 8 0.42 0.88 3.02
13 INT85885 Positive_regulation of SNAP25 8 0.69 2.74 2.84
14 INT173336 Gene_expression of GLUL 16 0.27 6.74 2.78
15 INT153997 Negative_regulation of Gene_expression of Slc17a6 2 0.59 3.01 2.42
16 INT114011 Negative_regulation of ATP1A2 5 0.45 6.12 2.41
17 INT126033 Localization of Slc17a6 4 0.77 0.75 2.35
18 INT139932 Regulation of Slc17a6 4 0.45 2.21 2.17
19 INT101582 Negative_regulation of SNAP25 9 0.57 4.34 2.12
20 INT49723 Localization of GLUL 5 0.27 0.67 2.1
21 INT128272 Positive_regulation of Gene_expression of Slc17a6 3 0.47 0.66 2.03
22 INT115303 Localization of SNAP25 8 0.73 1.43 1.82
23 INT151790 Binding of SNAP25 11 0.24 1.09 1.73
24 INT165459 Positive_regulation of SLC1A3 3 0.49 1.08 1.73
25 INT103959 Gene_expression of ATP1A2 3 0.67 2.47 1.68
26 INT165457 Negative_regulation of SLC1A3 3 0.42 1.46 1.56
27 INT179752 Positive_regulation of Gene_expression of SLC1A3 3 0.17 2.35 1.56
28 INT180249 Negative_regulation of GLUL 5 0.15 0.69 1.46
29 INT114013 Binding of ATP1A2 3 0.47 3.51 1.46
30 INT305492 Negative_regulation of Localization of Slc17a6 3 0.43 1.49 1.45
31 INT305490 Transcription of Slc17a6 5 0.72 0.43 1.44
32 INT305497 Localization of Slc17a6 4 0.75 1.48 1.42
33 INT118581 Positive_regulation of ATP1A2 3 0.21 1.81 1.4
34 INT305494 Positive_regulation of Slc17a6 1 0.50 2.3 1.34
35 INT120337 Positive_regulation of Phosphorylation of SNAP25 2 0.29 0.11 1.19
36 INT51591 Regulation of GLUL 3 0.11 2.62 1.15
37 INT251225 Binding of Slc17a6 2 0.37 1.9 1.1
38 INT165458 Regulation of Gene_expression of SLC1A3 1 0.23 0.26 1.08
39 INT179751 Negative_regulation of Gene_expression of SLC1A3 1 0.19 0.75 1.05
40 INT120336 Positive_regulation of Gene_expression of SNAP25 2 0.37 0 1.03
41 INT115304 Regulation of SNAP25 7 0.60 1.24 0.95
42 INT305495 Positive_regulation of Regulation of Slc17a6 1 0.47 1.72 0.83
43 INT139931 Regulation of Gene_expression of Slc17a6 1 0.62 0.39 0.83
44 INT106920 Positive_regulation of Slc17a6 2 0.47 0.15 0.82
45 INT352660 Transcription of SLC1A3 1 0.05 0.76 0.8
46 INT333952 Negative_regulation of Gene_expression of GLUL 1 0.15 1 0.71
47 INT179748 Regulation of SLC1A3 1 0.15 0.09 0.66
48 INT305498 Positive_regulation of Gene_expression of Slc17a6 1 0.50 1.13 0.54
49 INT120338 Regulation of Gene_expression of SNAP25 1 0.36 0 0.52
50 INT305486 Negative_regulation of Transcription of Slc17a6 1 0.43 0 0.46
51 INT352659 Positive_regulation of Transcription of SLC1A3 1 0.04 0.39 0.43
52 INT116167 Negative_regulation of Gene_expression of Slc17a6 1 0.42 0.06 0.38
53 INT196247 Negative_regulation of Localization of SNAP25 2 0.29 0.76 0.37
54 INT268130 Regulation of Phosphorylation of SNAP25 1 0.28 0.07 0.32
55 INT6705 Negative_regulation of Phosphorylation of GLUL 1 0.19 0.18 0.31
56 INT6707 Phosphorylation of GLUL 1 0.36 0.18 0.31
57 INT6702 Binding of GLUL 3 0.21 2.04 0.28
58 INT148625 Regulation of Transcription of Slc17a6 1 0.18 0.07 0.27
59 INT106918 Negative_regulation of Slc17a6 1 0.24 0 0.27
60 INT148624 Regulation of Gene_expression of Slc17a6 1 0.31 0.07 0.27
61 INT305487 Positive_regulation of Negative_regulation of Slc17a6 1 0.61 0.87 0.21
62 INT185337 Regulation of Gene_expression of GLUL 2 0.22 0.39 0.19
63 INT206487 Binding of SLC1A3 2 0.36 0.21 0.17
64 INT114012 Negative_regulation of Binding of ATP1A2 1 0.45 1.01 0.14
65 INT196239 Positive_regulation of Localization of SNAP25 1 0.47 0 0.13
66 INT333946 Transcription of GLUL 1 0.19 0.43 0.13
67 INT94891 Protein_catabolism of SNAP25 2 0.55 0.19 0.1
68 INT293259 Negative_regulation of Gene_expression of SNAP25 4 0.49 5.08 0.09
69 INT173323 Positive_regulation of Gene_expression of GLUL 2 0.12 0.23 0.08
70 INT309563 Transcription of SNAP25 1 0.42 0 0.08
71 INT250271 Localization of SLC1A3 1 0.20 0.77 0.04
72 INT227587 Regulation of Positive_regulation of GLUL 1 0.06 0.07 0.04
73 INT250268 Regulation of Localization of SLC1A3 1 0.12 0.77 0.04
74 INT227579 Positive_regulation of Regulation of GLUL 1 0.11 0.07 0.04
75 INT253781 Binding of Slc17a6 1 0.03 0 0
76 INT115305 Regulation of Localization of SNAP25 1 0.44 0 0
77 INT293260 Negative_regulation of Protein_catabolism of SNAP25 1 0.07 0 0
78 INT302015 Negative_regulation of Binding of SNAP25 1 0.27 0 0
79 INT333951 Regulation of Binding of GLUL 1 0.16 0.31 0
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