GO:0001547

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Name antral ovarian follicle growth
Categary Process
Go Slim No
Go Link GO:0001547
Unique Molecular Interactions 295
Total Molecular Interactions 378
Total Single Events 4061
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for antral ovarian follicle growth. They are ordered first by their pain relevance and then by number of times they were reported for antral ovarian follicle growth. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
2 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
3 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
4 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
5 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
6 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26
7 INT12138 Ins1 Negative_regulation of Chat 1 0.27 0.71 1.01
8 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
9 INT56742 LIF Positive_regulation of Chat 1 0.02 0.2 0.98
10 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
11 INT251706 Chat Regulation of Gene_expression of Acot1 1 0.06 1.64 0.85
12 INT251708 Chat Regulation of Acot1 1 0.03 1.64 0.84
13 INT12142 Ins1 Regulation of Chat 1 0.24 0.69 0.84
14 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
15 INT18447 Binding of Ache and Chat 2 0.33 0.33 0.73
16 INT68211 Binding of Calca and Chat 1 0.37 0 0.71
17 INT38057 Binding of Crp and Esr1 2 0.04 1.21 0.65
18 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61
19 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
20 INT106347 Igf1 Regulation of Chat 1 0.44 0 0.55
21 INT106346 Mtpn Regulation of Chat 1 0.06 0 0.52
22 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
23 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5
24 INT154014 Binding of Esr1 and Gabrg1 1 0.07 0.07 0.5
25 INT12143 Ngf Positive_regulation of Chat 1 0.45 0.29 0.49
26 INT56736 Cntf Positive_regulation of Chat 1 0.00 0.1 0.49
27 INT56745 CNTF Positive_regulation of Chat 1 0.02 0.1 0.49
28 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46
29 INT323840 Binding of Esr1 and Il1 1 0.04 0.9 0.42
30 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41
31 INT205567 Regulation of Binding of Fgf1 and Chat 1 0.29 0.28 0.41
32 INT205566 Binding of Fgf1 and Chat 1 0.24 0.28 0.41
33 INT61660 Binding of CHAT and CYP21A2 1 0.00 0 0.4
34 INT117361 Binding of Esr1 and sea 1 0.02 1.38 0.38
35 INT79504 Binding of Gad1 and Chat 1 0.35 0 0.38
36 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38
37 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
38 INT79507 Binding of Pvalb and Chat 1 0.06 0 0.38
39 INT117359 Binding of Esr1 and Wbc1 1 0.00 1.38 0.37
40 INT291555 Binding of ESR1 and Dlat 1 0.01 0.6 0.35
41 INT291554 Binding of ESR1 and St8sia2 1 0.01 0.49 0.33
42 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
43 INT304277 CCNE1 Positive_regulation of IL1RN 1 0.00 1.93 0.31
44 INT304278 CCNE1 Positive_regulation of IL8 1 0.02 1.93 0.31
45 INT304280 CCNE1 Positive_regulation of IL6 1 0.00 1.93 0.31
46 INT309156 Esr1 Regulation of Gene_expression of Dlat 1 0.05 1.06 0.3
47 INT140385 Spp1 Negative_regulation of FOXO3 1 0.04 1.29 0.3
48 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
49 INT158734 Esr1 Regulation of Esrrb 1 0.00 0.28 0.29
50 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
51 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28
52 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28
53 INT22722 Binding of Chat and Hc3 1 0.39 0 0.28
54 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27
55 INT323152 Binding of DBT and ESR1 2 0.02 1.29 0.27
56 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26
57 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26
58 INT186783 Binding of ESR1 and NRIP1 1 0.31 0.79 0.25
59 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
60 INT182346 Binding of Cd3e and Esr1 1 0.06 1.26 0.25
61 INT182349 Binding of Ms4a1 and Esr1 1 0.04 1.26 0.25
62 INT199971 IL6 Positive_regulation of ESR1 1 0.08 0.84 0.24
63 INT309160 Binding of Esr1 and Edc4 1 0.03 0.34 0.24
64 INT63203 INS Positive_regulation of ESR1 1 0.09 0.3 0.23
65 INT63198 POMC Positive_regulation of ESR1 1 0.14 0.3 0.23
66 INT270135 Binding of ESR1 and RALA 1 0.11 0.37 0.22
67 INT63192 PTH Positive_regulation of ESR1 1 0.20 0.29 0.22
68 INT308645 Binding of Esr1 and Itpr3 1 0.00 0 0.2
69 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19
70 INT322543 Binding of FOXO3 and Cdkn1b 1 0.08 0.84 0.19
71 INT222543 Il1a Regulation of Chat 1 0.01 0.64 0.19
72 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19
73 INT192219 CASP3 Regulation of ESR1 1 0.03 1.19 0.19
74 INT197618 Binding of Esr1 and Ppt1 1 0.01 0 0.18
75 INT173932 Binding of Esr1 and Il6 1 0.03 0.11 0.18
76 INT351088 Negative_regulation of ERBB2 Positive_regulation of FOXO3 1 0.17 0.66 0.18
77 INT19042 ESR1 Positive_regulation of GGT5 1 0.03 0.6 0.17
78 INT19045 ESR1 Positive_regulation of Salpa1 1 0.02 0.6 0.17
79 INT160929 Chat Positive_regulation of Penk 1 0.35 1.18 0.15
80 INT309154 Esr1 Positive_regulation of Gsdmc 1 0.01 0.44 0.15
81 INT309155 Negative_regulation of Esr1 Positive_regulation of Gsdmc 1 0.01 0.45 0.15
82 INT181752 Binding of CPOX and ESR1 1 0.02 0.89 0.14
83 INT291644 Binding of DST and ESR1 1 0.05 0.84 0.14
84 INT147863 Binding of CHAT and SLC18A3 1 0.34 0.8 0.14
85 INT347868 Ntf3 Negative_regulation of Negative_regulation of Chat 1 0.03 0.22 0.13
86 INT297312 Esr1 Positive_regulation of Scap 1 0.00 1.58 0.13
87 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13
88 INT86429 Binding of Hspb1 and Esr1 1 0.19 0.26 0.13
89 INT236588 Binding of Esr1 and Ins1 1 0.05 0.73 0.12
90 INT341827 Binding of ESR1 and TNC 1 0.14 0.63 0.11
91 INT341775 DBT Regulation of Binding of ESR1 1 0.02 0.1 0.11
92 INT252779 Binding of ESR1 and RAF1 1 0.01 2.03 0.11
93 INT220114 Tnfrsf1a Positive_regulation of Esr1 1 0.14 1.14 0.1
94 INT237819 Binding of Esr1 and soc 1 0.04 0 0.1
95 INT279407 Binding of ESR1 and IGKV2-19 1 0.02 0.4 0.1
96 INT125000 Binding of Esr1 and Tas2r108 1 0.04 0.33 0.1
97 INT201721 Ngf Regulation of Chat 1 0.02 0.4 0.1
98 INT237812 Esr1 Positive_regulation of Positive_regulation of soc 1 0.05 0.6 0.1
99 INT201747 Itpr3 Positive_regulation of Localization of Esr1 2 0.03 1.19 0.09
100 INT308662 Binding of Esr1 and Fdft1 1 0.00 0.05 0.09
101 INT232559 Map3k1 Positive_regulation of Esr1 1 0.19 0.26 0.09
102 INT261396 Nsdhl Positive_regulation of Transcription of Esr1 1 0.02 2.1 0.09
103 INT341776 ESR1 Positive_regulation of Gene_expression of SLC6A3 1 0.06 0.08 0.09
104 INT232557 Erbb2 Positive_regulation of Esr1 1 0.23 0.26 0.09
105 INT52836 ESR1 Positive_regulation of HSD17B7 1 0.43 0.41 0.09
106 INT192863 Binding of Ddit3 and Esr1 1 0.09 0.67 0.08
107 INT192860 Binding of Calr and Esr1 1 0.06 0.67 0.08
108 INT192865 Binding of Esr1 and Pdia3 1 0.07 0.67 0.08
109 INT192862 Binding of Esr1 and Hspa5 1 0.08 0.68 0.08
110 INT309159 Binding of Cav1 and Positive_regulation of Localization of Esr1 1 0.04 0 0.08
111 INT251710 Fig4 Regulation of Chat 1 0.03 0.23 0.08
112 INT199973 ESR1 Negative_regulation of EEF1B2P2 1 0.01 0.46 0.08
113 INT251705 Fig4 Regulation of Localization of Chat 1 0.05 0.23 0.08
114 INT38188 PGR Positive_regulation of Gene_expression of ESR1 1 0.42 0.22 0.07
115 INT237811 Binding of Esr1 and Stim1 1 0.09 0 0.07
116 INT339108 Binding of ESR1 and JUP 1 0.38 0.62 0.07
117 INT224293 AR Positive_regulation of Protein_catabolism of ESR1 1 0.24 0.4 0.07
118 INT237809 Esr1 Positive_regulation of Localization of Car2 1 0.09 0.66 0.07
119 INT206855 Binding of ESR1 and PPARA 1 0.03 1.21 0.07
120 INT272388 Esr1 Regulation of Transcription of Trpv6 1 0.03 0.13 0.06
121 INT197594 Esr1 Regulation of Esr2 1 0.04 0 0.06
122 INT187845 Binding of ESR1 and Esr2 1 0.01 0.17 0.06
123 INT300310 Akt1 Regulation of Foxo3 1 0.21 1.5 0.06
124 INT197592 Esr2 Regulation of Esr1 1 0.04 0 0.06
125 INT142744 Esr1 Regulation of Transcription of Trpv6 1 0.42 0 0.06
126 INT206846 ESR1 Regulation of Gene_expression of PLP1 1 0.06 1.02 0.05
127 INT242974 Mapk8 Negative_regulation of Positive_regulation of Esr1 1 0.01 1.39 0.05
128 INT236591 Binding of Esr1 and Positive_regulation of Tmed4 1 0.04 0.52 0.05
129 INT240726 Binding of Esr1 and Ca2 1 0.02 0.57 0.05
130 INT316248 ESR1 Regulation of Gene_expression of TRPM8 1 0.34 0.17 0.05
131 INT244461 CS Positive_regulation of ESR1 1 0.06 1.15 0.05
132 INT225493 Binding of Esr1 and Pprc1 2 0.01 0.17 0.04
133 INT335702 Esr1 Regulation of Calr 1 0.03 0 0.04
134 INT206848 PLP1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04
135 INT206853 ESR1 Positive_regulation of Gene_expression of PCP4 1 0.08 1.39 0.04
136 INT206845 ANXA1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04
137 INT201445 ESR1 Regulation of Slc6a3 1 0.02 0.05 0.04
138 INT206851 NR4A1 Regulation of Gene_expression of ESR1 1 0.08 0.9 0.04
139 INT236595 Binding of Esr1 and PELP1 1 0.27 0.17 0.04
140 INT206896 ESR1 Positive_regulation of Gene_expression of Nr1i3 1 0.00 0.36 0.04
141 INT206847 ESR1 Negative_regulation of Gene_expression of PTGER3 1 0.08 1.52 0.04
142 INT197917 Binding of ESR1 and Sh2b2 1 0.01 0 0.04
143 INT335703 Esr1 Regulation of Localization of Calr 1 0.03 0 0.04
144 INT206849 ESR1 Regulation of Gene_expression of ALDH1A1 1 0.11 2.26 0.04
145 INT206852 ESR1 Regulation of Gene_expression of CRABP2 1 0.08 1.52 0.04
146 INT183614 Binding of ESR1 and TMED4 2 0.02 0.13 0.03
147 INT278579 Esr1 Positive_regulation of Negative_regulation of Tac2 1 0.47 0.25 0.03
148 INT278289 Binding of DBP and ESR1 1 0.03 0.82 0.03
149 INT101159 Gene_expression of Bcl2 Positive_regulation of Gene_expression of CHAT 1 0.31 0.96 0.03
150 INT213902 ESR1 Positive_regulation of EGFR 1 0.48 0.31 0.03
151 INT331960 Positive_regulation of Binding of Esr1 and Tymp 1 0.00 0.15 0.03
152 INT331958 Binding of Esr1 and Tymp 1 0.00 0.15 0.03
153 INT245075 Binding of ESR1 and NR4A1 1 0.01 1.08 0.03
154 INT316773 Esr1 Positive_regulation of Ddit3 1 0.02 0.41 0.03
155 INT278294 Binding of ESR1 and SHBG 1 0.01 0.82 0.03
156 INT221682 Binding of Esr1 and FRTS 1 0.01 0.15 0.03
157 INT213905 ESR1 Positive_regulation of SRC 1 0.14 0.31 0.03
158 INT215872 Atf4 Regulation of Esr1 1 0.30 0.42 0.03
159 INT192914 Binding of ESR1 and GOPC 2 0.02 0.61 0
160 INT260342 Binding of Esr1 and Rcc1 1 0.05 0.99 0
161 INT198111 Binding of Esr1 and Esr2 1 0.05 0 0
162 INT335214 Binding of ESR1 and RARS 1 0.08 0.92 0
163 INT178638 Gh1 Regulation of Gene_expression of ESR1 1 0.01 0.47 0
164 INT206895 Binding of ESR1 and Aldh1a1 1 0.03 0 0
165 INT264663 Binding of ESR1 and PRL 1 0.22 0.18 0
166 INT98354 TXNRD1 Positive_regulation of Positive_regulation of ESR1 1 0.00 0.05 0
167 INT306500 Clu Regulation of Esr1 1 0.22 0.13 0
168 INT332958 Binding of Esr1 and Ppara 1 0.36 0.21 0
169 INT225559 Binding of Esr1 and Ncoa6 1 0.18 0 0
170 INT281609 Foxo3 Positive_regulation of Transcription of Trim63 1 0.29 0 0
171 INT342281 Binding of INS and Esr1 1 0.08 0.57 0
172 INT206854 ESR1 Regulation of IGF1 1 0.01 0.33 0
173 INT173771 Gh1 Regulation of Transcription of Esr1 1 0.00 0.13 0
174 INT189115 Binding of Esr1 and Tap1 1 0.07 0.05 0
175 INT120549 Binding of ESR1 and Mpo 1 0.26 0.05 0
176 INT199975 ESR1 Positive_regulation of PGR 1 0.05 0.11 0
177 INT197677 Binding of ESR1 and Arg1 1 0.04 0 0
178 INT264662 ESR1 Regulation of Gene_expression of PRL 1 0.43 0.21 0
179 INT197615 Esr1 Regulation of Gene_expression of Pgr 1 0.01 0.21 0
180 INT176289 Pcna Positive_regulation of Phosphorylation of Esr1 1 0.01 0.67 0
181 INT336994 CALR Negative_regulation of ESR1 1 0.04 0 0
182 INT206850 Binding of CRABP2 and ESR1 1 0.06 0 0
183 INT318222 GADD45A Regulation of FOXO3 1 0.16 0.52 0
184 INT245077 Binding of ESR1 and CXCL12 1 0.06 1.42 0
185 INT191062 Esr1 Regulation of Gene_expression of Bcl2 1 0.12 0.73 0
186 INT313596 ESR1 Positive_regulation of Gene_expression of PGR 1 0.05 1 0
187 INT219421 Binding of ESR1 and MALAT1 1 0.34 0.63 0
188 INT314740 Binding of ESR1 and Brca1 1 0.16 0.69 0
189 INT98353 THRB Negative_regulation of Positive_regulation of ESR1 1 0.00 0.09 0
190 INT191096 Negative_regulation of Binding of Apc and Esr1 1 0.05 1.07 0
191 INT208018 Col4a4 Regulation of Gene_expression of Esr1 1 0.06 0.69 0
192 INT224291 Negative_regulation of ESR1 Positive_regulation of CCND1 1 0.16 0.07 0
193 INT244457 CS Positive_regulation of Gene_expression of ESR1 1 0.07 0.67 0
194 INT192913 Binding of ESR1 and HAMP 1 0.02 0.72 0
195 INT314687 ESR1 Regulation of PGR 1 0.27 0.88 0
196 INT197911 Dlst Positive_regulation of Gene_expression of Esr1 1 0.03 0.34 0
197 INT254435 Binding of Esr1 and Best1 1 0.21 0.06 0
198 INT333928 Binding of CALR and ESR1 1 0.09 0.09 0
199 INT225533 Binding of Emr1 and Esr1 1 0.01 0 0
200 INT333929 Binding of ESR1 and ERLEC1 1 0.01 0.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for antral ovarian follicle growth. They are ordered first by their pain relevance and then by number of times they were reported in antral ovarian follicle growth. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
2 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
3 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
4 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
5 INT37296 Binding of Esr1 117 0.43 62.51 27.33
6 INT20462 Binding of ESR1 210 0.44 102.7 26.34
7 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
8 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
9 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
10 INT6381 Negative_regulation of Chat 51 0.59 19.68 15.86
11 INT92354 Localization of ESR1 77 0.75 33.04 15.51
12 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
13 INT4851 Positive_regulation of Chat 53 0.70 9.21 15.11
14 INT11945 Regulation of Chat 38 0.62 7.75 14.97
15 INT4736 Gene_expression of Chat 67 0.77 17.15 14.24
16 INT2038 Localization of Esr1 104 0.79 40.12 13.27
17 INT41728 Gene_expression of CHAT 65 0.75 42.19 12.73
18 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
19 INT15308 Localization of Chat 29 0.81 2.35 8.47
20 INT15687 Regulation of ESR1 91 0.60 40.42 7.95
21 INT110987 Transcription of ESR1 45 0.71 24.16 6.72
22 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29
23 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69
24 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51
25 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84
26 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57
27 INT117205 Transcription of Esr1 23 0.65 9.4 4.14
28 INT218955 Protein_catabolism of ESR1 9 0.92 3.95 3.74
29 INT20461 Binding of Esr1 34 0.48 9.58 3.66
30 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36
31 INT73918 Transcription of Esr1 21 0.66 8.74 3.12
32 INT31541 Regulation of Esr1 15 0.54 4.12 2.82
33 INT174727 Positive_regulation of Positive_regulation of ESR1 14 0.44 6.3 2.7
34 INT47386 Negative_regulation of CHAT 5 0.29 1.63 2.61
35 INT11943 Transcription of Chat 10 0.70 1.55 2.36
36 INT87374 Positive_regulation of CHAT 7 0.67 3.91 1.96
37 INT73913 Regulation of Gene_expression of Esr1 2 0.41 2.24 1.92
38 INT218959 Negative_regulation of Protein_catabolism of ESR1 3 0.37 0.97 1.9
39 INT96971 Positive_regulation of Gene_expression of Esr1 6 0.46 2.27 1.67
40 INT222089 Positive_regulation of Localization of Esr1 19 0.49 8.73 1.58
41 INT32900 Negative_regulation of Positive_regulation of Chat 3 0.43 1.91 1.45
42 INT58452 Positive_regulation of Negative_regulation of Chat 4 0.50 1.99 1.35
43 INT8511 Localization of Esr1 6 0.80 3.27 1.26
44 INT128752 Negative_regulation of Localization of Esr1 11 0.43 4.8 1.23
45 INT824 Negative_regulation of Negative_regulation of ESR1 3 0.42 1.53 1.18
46 INT44621 Binding of Chat 5 0.45 0.87 1.15
47 INT57188 Regulation of Gene_expression of Chat 4 0.45 1.89 1.12
48 INT57189 Negative_regulation of Gene_expression of Chat 5 0.56 1.35 1.07
49 INT81945 Negative_regulation of Binding of Esr1 3 0.32 0.55 1.06
50 INT71906 Regulation of Gene_expression of ESR1 22 0.41 11.01 0.98
51 INT30316 Regulation of CHAT 6 0.43 1.95 0.96
52 INT154468 Negative_regulation of Transcription of ESR1 3 0.29 1.14 0.96
53 INT173747 Regulation of Positive_regulation of Esr1 4 0.37 4.85 0.95
54 INT281594 Phosphorylation of Foxo3 3 0.67 21.16 0.95
55 INT236576 Positive_regulation of Binding of Esr1 3 0.41 2.39 0.92
56 INT154465 Negative_regulation of Transcription of Esr1 1 0.05 0 0.92
57 INT128755 Protein_catabolism of Esr1 10 0.57 4.61 0.9
58 INT56200 Negative_regulation of Negative_regulation of Chat 3 0.25 1.38 0.88
59 INT193070 Localization of CHAT 3 0.17 1.03 0.86
60 INT73914 Negative_regulation of Transcription of Esr1 3 0.39 0.75 0.84
61 INT174728 Positive_regulation of Transcription of ESR1 10 0.47 3.3 0.83
62 INT125092 Negative_regulation of Binding of ESR1 8 0.42 4.15 0.82
63 INT33818 Positive_regulation of Negative_regulation of Esr1 3 0.40 0.98 0.82
64 INT161778 Regulation of Gene_expression of Esr1 13 0.51 9.46 0.73
65 INT92082 Regulation of Binding of ESR1 5 0.45 2.41 0.73
66 INT239494 Regulation of Localization of Esr1 4 0.19 1.15 0.72
67 INT73917 Regulation of Transcription of Esr1 4 0.25 1.5 0.7
68 INT100626 Transcription of CHAT 4 0.51 1.94 0.69
69 INT44622 Positive_regulation of Binding of Chat 3 0.39 0.71 0.68
70 INT88188 Negative_regulation of Transcription of Chat 1 0.51 0 0.68
71 INT191177 Regulation of Localization of ESR1 7 0.42 2.04 0.64
72 INT9836 Negative_regulation of Negative_regulation of Esr1 3 0.29 0.95 0.63
73 INT58987 Positive_regulation of Ccne1 1 0.49 0 0.59
74 INT58988 Positive_regulation of Gene_expression of Ccne1 1 0.67 0 0.59
75 INT58989 Gene_expression of Ccne1 2 0.75 0.79 0.58
76 INT173748 Phosphorylation of Esr1 11 0.77 5.7 0.55
77 INT11942 Positive_regulation of Transcription of Chat 2 0.47 0.23 0.54
78 INT173744 Positive_regulation of Positive_regulation of Esr1 10 0.43 7.05 0.52
79 INT106973 Positive_regulation of Gene_expression of CHAT 3 0.44 0.8 0.5
80 INT190899 Negative_regulation of Phosphorylation of ESR1 3 0.33 1.01 0.49
81 INT240710 Positive_regulation of Regulation of Esr1 1 0.09 1.34 0.47
82 INT281589 Localization of Foxo3 2 0.61 7.91 0.42
83 INT174725 Positive_regulation of Localization of ESR1 8 0.47 2.45 0.41
84 INT85761 Positive_regulation of Gene_expression of Chat 5 0.30 1.43 0.39
85 INT268930 Regulation of Regulation of Esr1 2 0.41 0.48 0.38
86 INT178630 Positive_regulation of Negative_regulation of ESR1 2 0.04 0.64 0.35
87 INT236580 Regulation of Binding of Esr1 4 0.39 1.1 0.34
88 INT87388 Negative_regulation of Positive_regulation of CHAT 1 0.42 0.41 0.34
89 INT176586 Positive_regulation of Binding of ESR1 11 0.41 4.64 0.33
90 INT310379 Negative_regulation of FOXO3 2 0.42 1.28 0.32
91 INT183916 Negative_regulation of Binding of Esr1 1 0.06 0.91 0.32
92 INT95831 Regulation of Negative_regulation of Chat 1 0.09 0 0.32
93 INT192845 Negative_regulation of Positive_regulation of Esr1 2 0.35 1.15 0.31
94 INT304298 Positive_regulation of CCNE1 2 0.46 2.95 0.31
95 INT73915 Negative_regulation of Negative_regulation of Esr1 1 0.40 0.06 0.31
96 INT297904 Positive_regulation of Foxo3 6 0.57 8.19 0.29
97 INT281598 Negative_regulation of Phosphorylation of Foxo3 2 0.48 4.26 0.28
98 INT153772 Negative_regulation of Localization of ESR1 7 0.54 4.42 0.27
99 INT109433 Phosphorylation of Chat 1 0.15 0.65 0.24
100 INT218031 Regulation of Transcription of CHAT 1 0.27 0 0.24
101 INT96972 Positive_regulation of Binding of Esr1 4 0.22 1.35 0.21
102 INT297457 Regulation of Regulation of Chat 1 0.27 0.32 0.21
103 INT186021 Positive_regulation of Positive_regulation of Esr1 1 0.08 0 0.19
104 INT42569 Binding of Ccne1 1 0.21 0.38 0.19
105 INT219470 Positive_regulation of FOXO3 6 0.61 2.83 0.18
106 INT318235 Positive_regulation of Gene_expression of FOXO3 4 0.54 2.59 0.18
107 INT176571 Negative_regulation of Positive_regulation of ESR1 5 0.47 3.15 0.17
108 INT291955 Positive_regulation of Protein_catabolism of Esr1 1 0.06 0.14 0.17
109 INT269777 Regulation of Regulation of Esr1 2 0.02 1.17 0.16
110 INT297906 Binding of Foxo3 2 0.29 1.91 0.16
111 INT176461 Protein_catabolism of Esr1 1 0.12 0.37 0.16
112 INT183400 Positive_regulation of Transcription of Esr1 4 0.30 1.06 0.14
113 INT162109 Negative_regulation of Gene_expression of Esr1 4 0.16 2.41 0.12
114 INT300285 Positive_regulation of Localization of Foxo3 1 0.38 1.86 0.12
115 INT232556 Positive_regulation of Phosphorylation of Esr1 1 0.20 0.41 0.12
116 INT281605 Regulation of Foxo3 2 0.50 2.35 0.1
117 INT297461 Protein_catabolism of Chat 1 0.39 0.5 0.1
118 INT302244 Negative_regulation of CCNE1 1 0.01 1.03 0.1
119 INT318233 Gene_expression of FOXO3 6 0.60 4.37 0.09
120 INT300288 Positive_regulation of Positive_regulation of Foxo3 1 0.57 1.91 0.09
121 INT224299 Positive_regulation of Protein_catabolism of ESR1 3 0.64 1.43 0.07
122 INT178868 Regulation of Positive_regulation of ESR1 1 0.42 0.52 0.07
123 INT173183 Regulation of CCNE1 1 0.05 0.4 0.06
124 INT300290 Positive_regulation of Phosphorylation of Foxo3 1 0.41 4.25 0.06
125 INT253882 Positive_regulation of Localization of Esr1 1 0.30 1.21 0.06
126 INT159025 Negative_regulation of Localization of Chat 1 0.39 0 0.04
127 INT272379 Positive_regulation of Transcription of Esr1 1 0.04 0.13 0.04
128 INT226593 Positive_regulation of Positive_regulation of Chat 1 0.20 0.65 0.04
129 INT221677 Negative_regulation of Protein_catabolism of Esr1 1 0.08 0.15 0.03
130 INT300293 Positive_regulation of Regulation of Foxo3 1 0.38 0.88 0.03
131 INT302266 Negative_regulation of Phosphorylation of CCNE1 1 0.02 0.29 0.03
132 INT174726 Regulation of Regulation of ESR1 1 0.41 0.73 0.03
133 INT300299 Regulation of Phosphorylation of Foxo3 1 0.32 0.89 0.03
134 INT314725 Gene_expression of CCNE1 3 0.52 2.45 0
135 INT213578 Binding of FOXO3 3 0.33 2.2 0
136 INT277373 Phosphorylation of FOXO3 3 0.72 0.61 0
137 INT174724 Regulation of Transcription of ESR1 2 0.18 0.49 0
138 INT178629 Positive_regulation of Phosphorylation of ESR1 2 0.36 0.93 0
139 INT322522 Regulation of Positive_regulation of FOXO3 1 0.15 0 0
140 INT322531 Regulation of FOXO3 1 0.24 0.09 0
141 INT335681 Regulation of Negative_regulation of Esr1 1 0.03 0 0
142 INT173746 Regulation of Transcription of Esr1 1 0.04 0 0
143 INT300296 Negative_regulation of Foxo3 1 0.35 1.77 0
144 INT322528 Positive_regulation of Localization of FOXO3 1 0.24 0.09 0
145 INT300292 Transcription of Foxo3 1 0.59 0.77 0
146 INT223607 Regulation of Phosphorylation of ESR1 1 0.35 0.65 0
147 INT204068 Negative_regulation of Gene_expression of Ccne1 1 0.03 0.47 0
148 INT169264 Regulation of Localization of Chat 1 0.21 0.08 0
149 INT314716 Positive_regulation of Gene_expression of CCNE1 1 0.16 1.48 0
150 INT322529 Localization of FOXO3 1 0.38 1.18 0
151 INT300289 Positive_regulation of Transcription of Foxo3 1 0.38 0.77 0
152 INT322532 Negative_regulation of Phosphorylation of FOXO3 1 0.23 0.25 0
153 INT302253 Phosphorylation of CCNE1 1 0.03 0.29 0
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