GO:0001556

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Name oocyte maturation
Categary Process
Go Slim No
Go Link GO:0001556
Unique Molecular Interactions 81
Total Molecular Interactions 98
Total Single Events 558
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for oocyte maturation. They are ordered first by their pain relevance and then by number of times they were reported for oocyte maturation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT19299 ANG Regulation of AVP 1 0.25 0 0.82
2 INT251161 Binding of Trpv1 and Rxfp2 1 0.06 0.18 0.55
3 INT164264 TGM7 Negative_regulation of CCNB1 1 0.07 1.08 0.53
4 INT19297 ANG Positive_regulation of AVP 1 0.28 0 0.46
5 INT19298 ANG Regulation of OXT 1 0.07 0 0.41
6 INT140385 Spp1 Negative_regulation of FOXO3 1 0.04 1.29 0.3
7 INT242215 Binding of ANG and OLR1 1 0.02 1.63 0.25
8 INT30071 Gm8212 Regulation of Pde3a 1 0.00 0 0.2
9 INT322543 Binding of FOXO3 and Cdkn1b 1 0.08 0.84 0.19
10 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19
11 INT319311 Binding of Glud1 and Ptk2b 1 0.36 0 0.19
12 INT351088 Negative_regulation of ERBB2 Positive_regulation of FOXO3 1 0.17 0.66 0.18
13 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18
14 INT323757 Negative_regulation of ACE2 Negative_regulation of ANG 1 0.18 1.73 0.17
15 INT323756 Negative_regulation of ACE2 Positive_regulation of ANG 1 0.19 1.73 0.17
16 INT263179 PDE3A Regulation of COPD 1 0.00 1 0.15
17 INT206070 ANG Positive_regulation of Transcription of IL6 1 0.05 1.5 0.15
18 INT263177 Binding of PDE3A and COPD 1 0.01 1 0.15
19 INT319314 Binding of Ptk2b and Rbm39 1 0.01 0.08 0.14
20 INT319316 Binding of GRIN1 and Ptk2b 1 0.52 0.08 0.14
21 INT102885 Binding of ANG and ACE 2 0.17 0.37 0.13
22 INT281911 Binding of ANG and MAS1 1 0.05 0.39 0.13
23 INT222465 Binding of Calcrl and Rxfp2 1 0.02 0 0.12
24 INT36374 Binding of INSL3 and KLF1 1 0.00 0.51 0.12
25 INT36373 Binding of AHR and INSL3 1 0.00 0.5 0.12
26 INT36375 Binding of FUT4 and INSL3 1 0.05 0.5 0.12
27 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1
28 INT281912 Binding of AGTR2 and ANG 1 0.13 0.37 0.1
29 INT281899 Binding of ANG and NOS3 1 0.12 0.37 0.1
30 INT306274 Binding of CCNB1 and CDK1 1 0.19 0.13 0.09
31 INT321296 Rxfp2 Regulation of G6pc 1 0.07 0.07 0.09
32 INT321298 Rxfp2 Regulation of Pck1 1 0.10 0.07 0.09
33 INT355604 VEGFA Regulation of Positive_regulation of Ptk2b 1 0.22 1.47 0.08
34 INT206072 ANG Positive_regulation of IL6 1 0.05 0.5 0.08
35 INT21649 ANG Regulation of Alb 1 0.04 0.64 0.07
36 INT206080 ANG Regulation of Gene_expression of IL6 1 0.03 0.4 0.07
37 INT319309 Egr2 Regulation of Ptk2b 1 0.29 0.37 0.07
38 INT131149 Rxfp2 Positive_regulation of Localization of Ins1 1 0.23 0 0.07
39 INT206063 ANG Positive_regulation of Gene_expression of KRT20 1 0.00 1.01 0.07
40 INT333256 Gene_expression of Cxcl12 Negative_regulation of Ptk2b 1 0.10 0.99 0.07
41 INT222479 Binding of Ramp1 and Rxfp2 1 0.01 0 0.06
42 INT300310 Akt1 Regulation of Foxo3 1 0.21 1.5 0.06
43 INT222478 Binding of Calca and Rxfp2 1 0.02 0 0.06
44 INT281906 BDKRB2 Positive_regulation of ANG 1 0.11 0.51 0.05
45 INT336132 Binding of AGTR1 and ANG 1 0.00 0.38 0.05
46 INT316489 Stat3 Positive_regulation of Transcription of Ccnb1 1 0.02 1.27 0.04
47 INT263197 Binding of PDE3A and Pde5a 1 0.03 0.18 0.04
48 INT89385 INS Positive_regulation of Phosphorylation of PTK2B 1 0.15 0.59 0.04
49 INT102887 Binding of ANG and SGCG 1 0.37 0 0.03
50 INT237206 LGALS4 Regulation of Gene_expression of Ccnb1 1 0.05 0 0.03
51 INT234178 Binding of BRCA1 and BRCA2 2 0.40 1.52 0
52 INT313597 Binding of BRCA2 and TOX3 1 0.11 0.7 0
53 INT182397 NFYA Regulation of CCNB1 1 0.00 0.09 0
54 INT281609 Foxo3 Positive_regulation of Transcription of Trim63 1 0.29 0 0
55 INT206079 ANG Regulation of KRT20 1 0.00 0.54 0
56 INT314742 Binding of RAD51 and Brca2 1 0.06 1.05 0
57 INT234182 Binding of BRCA2 and PALB2 1 0.41 1.43 0
58 INT206069 ANG Positive_regulation of Gene_expression of IL6 1 0.05 0.51 0
59 INT182402 E2F2 Regulation of CCNB1 1 0.00 0.09 0
60 INT121478 Binding of Pde3a and Positive_regulation of Localization of Ins1 1 0.24 0 0
61 INT318222 GADD45A Regulation of FOXO3 1 0.16 0.52 0
62 INT336129 Binding of ANG and EXTL3 1 0.01 0.38 0
63 INT318218 SIRT1 Positive_regulation of Binding of FOXO3 1 0.44 0.51 0
64 INT322547 FOXO3 Regulation of Transcription of Cdkn1b 1 0.12 0.32 0
65 INT336131 Binding of ANG and ATP6AP2 1 0.00 0.38 0
66 INT318221 SIRT1 Positive_regulation of FOXO3 1 0.41 0.63 0
67 INT322548 FOXO3 Regulation of Cdkn1b 1 0.09 0.23 0
68 INT260074 Binding of BRCA2 and PTCH1 1 0.40 0.15 0
69 INT307307 COMP Positive_regulation of EREG 1 0.01 0.46 0
70 INT300303 Binding of Gk and Foxo3 1 0.09 1.53 0
71 INT281904 ANG Positive_regulation of PTGIS 1 0.04 0 0
72 INT307309 Binding of CALR and EREG 1 0.00 0.83 0
73 INT327099 Binding of EGF and EREG 1 0.05 0.35 0
74 INT336130 Binding of ANG and REN 1 0.06 0.38 0
75 INT318216 SIRT1 Positive_regulation of Gene_expression of FOXO3 1 0.36 0.52 0
76 INT279888 Binding of Rec8 and Nipbl 1 0.01 0.81 0
77 INT260072 Binding of BRCA2 and FANCC 1 0.37 0.63 0
78 INT307308 Binding of COMP and EREG 1 0.01 0.41 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for oocyte maturation. They are ordered first by their pain relevance and then by number of times they were reported in oocyte maturation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT29740 Gene_expression of ANG 55 0.78 24.53 9.86
2 INT121471 Negative_regulation of Pde3a 24 0.34 13.79 4.73
3 INT24279 Gene_expression of INSL3 11 0.75 12.46 2.8
4 INT68857 Positive_regulation of Rxfp2 5 0.34 1.51 1.86
5 INT119905 Negative_regulation of PDE3A 5 0.18 5 1.77
6 INT29739 Positive_regulation of ANG 11 0.69 4.37 1.75
7 INT102893 Positive_regulation of Gene_expression of ANG 10 0.69 5.62 1.71
8 INT152385 Gene_expression of Rxfp2 2 0.30 0.86 1.59
9 INT251834 Negative_regulation of Gene_expression of ANG 5 0.59 3.95 1.38
10 INT78692 Regulation of PTK2B 2 0.47 0.29 1.28
11 INT70138 Positive_regulation of Ccnb1 7 0.41 4.31 1.26
12 INT319293 Phosphorylation of Ptk2b 9 0.80 3.14 1.24
13 INT19303 Regulation of ANG 3 0.62 1.08 1.09
14 INT221743 Binding of Rxfp2 3 0.09 0.64 1.09
15 INT290411 Gene_expression of Ptk2b 10 0.65 3.72 1.01
16 INT281594 Phosphorylation of Foxo3 3 0.67 21.16 0.95
17 INT236927 Positive_regulation of Ptk2b 9 0.67 3.41 0.94
18 INT118538 Binding of ANG 5 0.47 3.02 0.92
19 INT113841 Gene_expression of CCNB1 11 0.75 3.46 0.86
20 INT109079 Negative_regulation of ANG 4 0.57 2.2 0.8
21 INT147433 Gene_expression of BRCA2 7 0.62 7.02 0.79
22 INT89340 Positive_regulation of EREG 5 0.69 4.98 0.77
23 INT177533 Negative_regulation of Binding of Pde3a 1 0.21 2.46 0.76
24 INT98784 Gene_expression of Ccnb1 11 0.59 4.53 0.75
25 INT113623 Regulation of Rxfp2 3 0.13 0.84 0.65
26 INT162911 Gene_expression of PDE3A 2 0.24 2.47 0.65
27 INT113617 Positive_regulation of Regulation of Rxfp2 1 0.23 0.86 0.6
28 INT143278 Regulation of Gene_expression of ANG 2 0.62 1.13 0.59
29 INT319254 Localization of Ptk2b 1 0.78 0.26 0.46
30 INT319284 Binding of Ptk2b 1 0.36 0.9 0.45
31 INT121469 Binding of Pde3a 2 0.23 1.42 0.44
32 INT109920 Positive_regulation of PTK2B 5 0.43 2.21 0.43
33 INT281589 Localization of Foxo3 2 0.61 7.91 0.42
34 INT319286 Transcription of Ptk2b 1 0.52 1.17 0.4
35 INT109922 Negative_regulation of PTK2B 3 0.26 1.63 0.39
36 INT89341 Gene_expression of EREG 3 0.78 2.38 0.38
37 INT109919 Positive_regulation of Positive_regulation of PTK2B 1 0.31 0.09 0.35
38 INT89342 Transcription of EREG 1 0.69 1.22 0.35
39 INT237161 Regulation of Ccnb1 5 0.17 2.71 0.32
40 INT310379 Negative_regulation of FOXO3 2 0.42 1.28 0.32
41 INT219588 Negative_regulation of Gene_expression of Pde3a 1 0.25 0 0.32
42 INT319276 Positive_regulation of Phosphorylation of Ptk2b 1 0.49 0.62 0.32
43 INT219563 Gene_expression of Pde3a 1 0.39 0 0.32
44 INT89339 Regulation of EREG 2 0.27 1.86 0.31
45 INT297904 Positive_regulation of Foxo3 6 0.57 8.19 0.29
46 INT281598 Negative_regulation of Phosphorylation of Foxo3 2 0.48 4.26 0.28
47 INT102890 Localization of ANG 9 0.72 0.41 0.26
48 INT173223 Negative_regulation of BRCA2 7 0.54 6.79 0.25
49 INT36385 Positive_regulation of Gene_expression of INSL3 1 0.08 0.89 0.24
50 INT98783 Negative_regulation of Gene_expression of Ccnb1 1 0.26 0.69 0.21
51 INT30069 Regulation of Pde3a 1 0.06 0 0.2
52 INT19359 Binding of BRCA2 5 0.47 2.63 0.19
53 INT89400 Phosphorylation of PTK2B 4 0.38 1.16 0.19
54 INT219470 Positive_regulation of FOXO3 6 0.61 2.83 0.18
55 INT318235 Positive_regulation of Gene_expression of FOXO3 4 0.54 2.59 0.18
56 INT89690 Binding of Brca2 2 0.37 1.8 0.18
57 INT319247 Regulation of Ptk2b 1 0.60 0 0.18
58 INT263126 Negative_regulation of Binding of PDE3A 1 0.13 0.62 0.18
59 INT219576 Positive_regulation of Gene_expression of Pde3a 1 0.29 0 0.17
60 INT297906 Binding of Foxo3 2 0.29 1.91 0.16
61 INT36381 Binding of INSL3 1 0.06 0.65 0.15
62 INT89691 Regulation of Brca2 1 0.23 0.56 0.13
63 INT89409 Negative_regulation of Phosphorylation of PTK2B 2 0.13 0.89 0.12
64 INT300285 Positive_regulation of Localization of Foxo3 1 0.38 1.86 0.12
65 INT281605 Regulation of Foxo3 2 0.50 2.35 0.1
66 INT135555 Localization of PTK2B 1 0.57 0.32 0.1
67 INT318233 Gene_expression of FOXO3 6 0.60 4.37 0.09
68 INT306284 Binding of CCNB1 1 0.28 0.13 0.09
69 INT300288 Positive_regulation of Positive_regulation of Foxo3 1 0.57 1.91 0.09
70 INT336014 Regulation of INSL3 1 0.26 0.33 0.09
71 INT263134 Binding of PDE3A 1 0.15 0.47 0.09
72 INT226414 Negative_regulation of Ccnb1 2 0.02 2.16 0.08
73 INT234186 Localization of BRCA2 2 0.69 1.48 0.07
74 INT221744 Protein_catabolism of Rxfp2 1 0.13 0 0.07
75 INT113842 Negative_regulation of CCNB1 1 0.40 0.53 0.06
76 INT300290 Positive_regulation of Phosphorylation of Foxo3 1 0.41 4.25 0.06
77 INT242229 Negative_regulation of Positive_regulation of ANG 1 0.08 0.63 0.06
78 INT336137 Negative_regulation of Binding of ANG 1 0.08 0.38 0.05
79 INT316438 Transcription of Ccnb1 1 0.02 1.24 0.04
80 INT263142 Positive_regulation of Negative_regulation of PDE3A 1 0.15 0.15 0.03
81 INT307325 Negative_regulation of Gene_expression of EREG 1 0.01 0.31 0.03
82 INT300293 Positive_regulation of Regulation of Foxo3 1 0.38 0.88 0.03
83 INT332373 Binding of Ccnb1 1 0.34 0 0.03
84 INT329787 Regulation of CCNB1 1 0.08 1.21 0.03
85 INT263131 Localization of PDE3A 1 0.23 0.35 0.03
86 INT300299 Regulation of Phosphorylation of Foxo3 1 0.32 0.89 0.03
87 INT213578 Binding of FOXO3 3 0.33 2.2 0
88 INT277373 Phosphorylation of FOXO3 3 0.72 0.61 0
89 INT200683 Gene_expression of PTK2B 2 0.67 1.02 0
90 INT167536 Positive_regulation of BRCA2 2 0.49 0.29 0
91 INT249788 Positive_regulation of Gene_expression of Ccnb1 2 0.44 0.51 0
92 INT234191 Positive_regulation of Localization of BRCA2 1 0.46 0.68 0
93 INT322522 Regulation of Positive_regulation of FOXO3 1 0.15 0 0
94 INT322531 Regulation of FOXO3 1 0.24 0.09 0
95 INT162919 Regulation of Transcription of PDE3A 1 0.06 0 0
96 INT314708 Gene_expression of Brca2 1 0.41 1.75 0
97 INT323760 Protein_catabolism of ANG 1 0.24 0.44 0
98 INT289873 Negative_regulation of Gene_expression of CCNB1 1 0.15 0 0
99 INT222604 Localization of Rxfp2 1 0.09 0.27 0
100 INT162923 Regulation of PDE3A 1 0.06 0 0
101 INT243389 Transcription of PTK2B 1 0.64 0.52 0
102 INT314707 Regulation of Transcription of Brca2 1 0.27 0.56 0
103 INT289864 Positive_regulation of CCNB1 1 0.25 0 0
104 INT289859 Localization of CCNB1 1 0.24 0.27 0
105 INT200665 Negative_regulation of Gene_expression of PTK2B 1 0.04 0.69 0
106 INT279867 Binding of Rec8 1 0.01 0.81 0
107 INT263132 Phosphorylation of PDE3A 1 0.25 0.19 0
108 INT300296 Negative_regulation of Foxo3 1 0.35 1.77 0
109 INT314705 Transcription of Brca2 1 0.42 0.56 0
110 INT263119 Positive_regulation of Phosphorylation of PDE3A 1 0.21 0.19 0
111 INT322528 Positive_regulation of Localization of FOXO3 1 0.24 0.09 0
112 INT289860 Negative_regulation of Positive_regulation of CCNB1 1 0.15 0 0
113 INT300292 Transcription of Foxo3 1 0.59 0.77 0
114 INT281924 Transcription of ANG 1 0.39 0.1 0
115 INT289871 Positive_regulation of Gene_expression of CCNB1 1 0.25 0.41 0
116 INT263123 Positive_regulation of PDE3A 1 0.21 0.19 0
117 INT256925 Protein_catabolism of Ccnb1 1 0.24 0.74 0
118 INT173224 Regulation of BRCA2 1 0.21 1.3 0
119 INT263136 Positive_regulation of Positive_regulation of PDE3A 1 0.21 0.19 0
120 INT322529 Localization of FOXO3 1 0.38 1.18 0
121 INT256906 Regulation of Gene_expression of Ccnb1 1 0.17 0.39 0
122 INT331145 Phosphorylation of Ccnb1 1 0.17 0.58 0
123 INT281916 Negative_regulation of Transcription of ANG 1 0.23 0.1 0
124 INT162904 Transcription of PDE3A 1 0.07 0 0
125 INT300289 Positive_regulation of Transcription of Foxo3 1 0.38 0.77 0
126 INT156922 Positive_regulation of Phosphorylation of PTK2B 1 0.23 0 0
127 INT290418 Regulation of Gene_expression of Ptk2b 1 0.17 0.1 0
128 INT279838 Protein_catabolism of Rec8 1 0.02 0.81 0
129 INT322532 Negative_regulation of Phosphorylation of FOXO3 1 0.23 0.25 0
130 INT279842 Regulation of Rec8 1 0.01 0.6 0
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