GO:0001568

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Name blood vessel development
Categary Process
Go Slim No
Go Link GO:0001568
Unique Molecular Interactions 830
Total Molecular Interactions 1124
Total Single Events 9059
Pain Genes Associated 72

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for blood vessel development. They are ordered first by their pain relevance and then by number of times they were reported for blood vessel development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
2 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
3 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
4 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
5 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
6 INT162482 Binding of Agt and Vta1 1 0.23 0 1.27
7 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
8 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09
9 INT107938 POMC Positive_regulation of Gene_expression of TGFBR2 1 0.42 1.09 1.07
10 INT221 Chd7 Negative_regulation of Th 1 0.02 0 1.04
11 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02
12 INT148327 Binding of Pkd1 and Trpv1 1 0.52 2.23 1.01
13 INT154236 Binding of TBX3 and Ugt2b7 1 0.41 0.74 1
14 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
15 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
16 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
17 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
18 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
19 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
20 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
21 INT61587 Agt Negative_regulation of REN 1 0.00 0.42 0.91
22 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
23 INT74872 Igh-Dex Positive_regulation of Chd7 1 0.01 0.5 0.89
24 INT69424 Binding of Agt and Oprd1 1 0.14 0 0.84
25 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
26 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
27 INT107937 POMC Regulation of Gene_expression of TGFBR2 1 0.28 0.82 0.81
28 INT34458 AGT Negative_regulation of PENK 1 0.00 0 0.81
29 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8
30 INT47143 Negative_regulation of Agt Positive_regulation of Avp 1 0.22 0 0.79
31 INT39095 Negative_regulation of Agt Positive_regulation of Localization of Ren 1 0.38 0 0.73
32 INT317585 Binding of Lbp and Ppap2b 1 0.03 0.78 0.72
33 INT317586 Binding of SCLY and Ppap2b 1 0.00 0.78 0.72
34 INT243169 EGFL7 Positive_regulation of Gene_expression of PPBP 1 0.02 0.67 0.72
35 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
36 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
37 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68
38 INT141063 Agt Regulation of Agtr1a 1 0.28 1.18 0.68
39 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
40 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66
41 INT47145 Penk Negative_regulation of Agt 1 0.06 0 0.66
42 INT162878 Agt Regulation of Ang 1 0.21 1.15 0.66
43 INT259776 Fbn2 Regulation of Negative_regulation of Agtr1a 1 0.00 1.42 0.66
44 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
45 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
46 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64
47 INT259768 Positive_regulation of Agtr1a Regulation of Etf1 1 0.00 1.32 0.62
48 INT57421 Oprd1 Regulation of Agt 1 0.29 0 0.62
49 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59
50 INT56116 Agt Positive_regulation of Lhb 1 0.15 0 0.58
51 INT56117 Agt Positive_regulation of Positive_regulation of CGA 1 0.00 0 0.56
52 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
53 INT73367 Agt Negative_regulation of Localization of Calca 1 0.43 0.26 0.54
54 INT34459 AGT Negative_regulation of MBTPS1 1 0.01 0 0.54
55 INT55445 Positive_regulation of Ahr Regulation of Mme 1 0.23 0 0.53
56 INT79809 Binding of Agtr1a and Adra1a 1 0.02 0.23 0.53
57 INT132438 Binding of AGT and OXTR 1 0.08 1.03 0.53
58 INT256019 Agt Negative_regulation of Lnpep 1 0.23 1.76 0.53
59 INT147576 Positive_regulation of Ahr Positive_regulation of Gene_expression of Scrg1 1 0.00 0.17 0.52
60 INT192159 Mmp14 Regulation of Protein_catabolism of Col1a1 1 0.02 1.01 0.52
61 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
62 INT106744 Binding of CRP and EGFL7 2 0.07 2.35 0.51
63 INT162503 AHR Regulation of CYP1A2 3 0.61 0.18 0.5
64 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
65 INT302838 TNF Positive_regulation of Sox18 1 0.00 0.71 0.5
66 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5
67 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
68 INT39078 Binding of Agt and Penk 1 0.24 0.42 0.48
69 INT47144 Negative_regulation of Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
70 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
71 INT47146 Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
72 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
73 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
74 INT155881 Binding of CDX2 and KRAS 1 0.40 1.51 0.47
75 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
76 INT39077 Agt Negative_regulation of Prss12 1 0.05 0.44 0.46
77 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
78 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
79 INT117776 Binding of Ptk2 and Regulation of Phosphorylation of Ddr1 1 0.10 0.17 0.46
80 INT151958 Negative_regulation of Agt Positive_regulation of Agtrap 1 0.39 0 0.44
81 INT115914 AHR Regulation of Gene_expression of PPIG 1 0.25 0.36 0.44
82 INT151959 Agt Positive_regulation of Agtrap 1 0.63 0 0.44
83 INT115916 AHR Regulation of Gene_expression of SLC45A2 1 0.64 0.36 0.44
84 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
85 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43
86 INT184543 Agt Positive_regulation of Ccl2 1 0.16 3.18 0.43
87 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
88 INT36459 Binding of Agt and Positive_regulation of Localization of Avp 1 0.38 0.19 0.43
89 INT115915 AHR Regulation of Gene_expression of CYP2B6 1 0.06 0.36 0.43
90 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
91 INT242992 Binding of Agt and Ppara 1 0.20 1.44 0.42
92 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
93 INT320810 Protein_catabolism of COL1A2 Positive_regulation of Localization of CYP27A1 1 0.04 1.05 0.4
94 INT36460 Binding of Agt and Avp 1 0.28 0.16 0.4
95 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
96 INT278932 Binding of Agtr1a and H3 1 0.00 0 0.39
97 INT64384 Agt Negative_regulation of Son 1 0.26 0 0.39
98 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39
99 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
100 INT39092 Agt Negative_regulation of Ren 1 0.39 0 0.37
101 INT329449 IL17A Regulation of Gene_expression of Vegfa 1 0.28 0.63 0.36
102 INT53257 CALCRL Negative_regulation of Binding of Agt 1 0.00 0 0.36
103 INT44112 Agt Regulation of Penk 1 0.08 0 0.35
104 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
105 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
106 INT4638 Binding of Agt and Adarb1 3 0.01 0 0.34
107 INT330122 Agt Positive_regulation of Gene_expression of Agtr1a 1 0.03 0.69 0.34
108 INT352232 VEGFA Negative_regulation of Vegfa 1 0.02 0.21 0.34
109 INT330121 Agtr1a Positive_regulation of Gene_expression of Bdkrb1 1 0.05 0.68 0.34
110 INT330119 Agt Positive_regulation of Gene_expression of Bdkrb1 1 0.37 0.63 0.34
111 INT162157 Binding of SGCG and Agt 1 0.33 0.35 0.33
112 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
113 INT147436 Agt Positive_regulation of Gene_expression of Ros1 1 0.02 0.5 0.33
114 INT242995 Agt Positive_regulation of Spp1 1 0.36 1.82 0.33
115 INT229363 Negative_regulation of Binding of Agt and Agtr1a 2 0.22 0.9 0.32
116 INT44127 Agt Negative_regulation of DSPP 1 0.02 0 0.32
117 INT329448 IL17A Positive_regulation of Gene_expression of Vegfa 1 0.45 0.59 0.32
118 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
119 INT56115 Agt Regulation of Lhb 1 0.16 0 0.32
120 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31
121 INT104932 AHR Positive_regulation of CYP1A1 1 0.43 0.83 0.31
122 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
123 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
124 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
125 INT179838 Col3a1 Regulation of Negative_regulation of Il11 1 0.21 0 0.29
126 INT295360 Ntn1 Positive_regulation of Ptk2 1 0.09 0.51 0.29
127 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28
128 INT116853 Chdh Regulation of Positive_regulation of Agt 1 0.11 0.19 0.28
129 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
130 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
131 INT214615 FOXC1 Positive_regulation of Gene_expression of Ang 1 0.01 0.29 0.28
132 INT137014 Positive_regulation of Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
133 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
134 INT137012 Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
135 INT214594 Binding of FOXC1 and IBD9 1 0.00 1.81 0.28
136 INT45541 Agt Positive_regulation of Lnpep 1 0.03 0 0.27
137 INT45545 Agt Positive_regulation of Oxt 1 0.23 0 0.27
138 INT109538 Lox Negative_regulation of Transcription of VEGFA 1 0.30 0.69 0.26
139 INT126550 Agt Positive_regulation of Gene_expression of Nsfl1c 1 0.39 1.07 0.26
140 INT242991 Agt Positive_regulation of Gene_expression of Spp1 1 0.21 0.66 0.26
141 INT9528 Agt Positive_regulation of Localization of Pomc 2 0.50 0.14 0.25
142 INT109539 Lox Negative_regulation of VEGFA 1 0.40 0.68 0.25
143 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
144 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25
145 INT271446 Thy1 Regulation of Col1a1 1 0.05 0.61 0.25
146 INT126547 Agt Positive_regulation of Nfkb1 1 0.46 0.99 0.25
147 INT126548 Negative_regulation of Agt Positive_regulation of Nfkb1 1 0.29 0.99 0.25
148 INT297258 Binding of Agt and Agtr2 1 0.23 0.7 0.25
149 INT158621 Binding of SIGMAR1 and Sphk1 1 0.01 0 0.25
150 INT126553 Agt Positive_regulation of Nfkb1 1 0.06 0.99 0.25
151 INT190052 Binding of Cdx2 and Ebp 1 0.08 0.82 0.24
152 INT256028 Binding of Agt and Lnpep 1 0.19 1.16 0.24
153 INT279959 Tnfrsf1b Negative_regulation of Ahr 1 0.10 0.98 0.24
154 INT41588 Binding of AGT and Lhb 1 0.00 0 0.24
155 INT41589 Binding of AGT and Prl 1 0.00 0 0.24
156 INT126551 Agt Positive_regulation of Gene_expression of Ptgs1 1 0.25 0.92 0.24
157 INT126552 Agt Positive_regulation of Gene_expression of Ptgs2 1 0.32 0.92 0.24
158 INT252784 ROS1 Positive_regulation of Gene_expression of COL1A1 1 0.05 1.86 0.24
159 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23
160 INT115875 Col5a1 Positive_regulation of Localization of Gcg 1 0.08 0 0.23
161 INT126549 Agt Positive_regulation of Ptgs2 1 0.32 0.9 0.23
162 INT179186 Fcer2a Regulation of Positive_regulation of Ahr 1 0.05 1.23 0.23
163 INT312517 Rapgef1 Negative_regulation of Rbp4 1 0.01 0.9 0.22
164 INT172826 Binding of Tnfsf4 and T2dm2 1 0.00 5.97 0.22
165 INT285639 Col3a1 Regulation of Tnfrsf12a 1 0.19 0.16 0.22
166 INT118838 Gene_expression of Vegfa Positive_regulation of Gene_expression of Mb 1 0.44 0.4 0.22
167 INT297257 Agtr1a Positive_regulation of Agtr2 1 0.27 0.59 0.22
168 INT137611 Crh Positive_regulation of Vegfa 1 0.43 0.49 0.21
169 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
170 INT137612 Crh Positive_regulation of Positive_regulation of Vegfa 1 0.43 0.43 0.21
171 INT163863 Binding of MIB1 and Vim 1 0.02 1.06 0.21
172 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
173 INT316810 Sparc Regulation of Col1a1 1 0.13 0.48 0.21
174 INT114837 Il1b Negative_regulation of Vegfa 1 0.26 3.04 0.21
175 INT353285 Prdx2 Regulation of Gene_expression of Col1a2 1 0.02 0.73 0.21
176 INT163864 Binding of MIB1 and Ema 1 0.04 1.07 0.21
177 INT116466 Vegfa Positive_regulation of Amfr 1 0.07 1.41 0.21
178 INT222566 Agt Positive_regulation of Localization of Prl 1 0.08 0.23 0.21
179 INT137610 Crh Positive_regulation of Localization of Vegfa 1 0.43 0.49 0.21
180 INT229360 Agt Positive_regulation of Agtr1a 2 0.48 1.26 0.2
181 INT225099 ZNF630 Positive_regulation of Gene_expression of COL1A1 1 0.00 0.17 0.2
182 INT275159 Agt Positive_regulation of Phosphorylation of Stat3 1 0.04 1.44 0.2
183 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
184 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
185 INT115142 TGM7 Positive_regulation of Gene_expression of CITED2 1 0.02 0.45 0.2
186 INT249993 Binding of Agt and Igkv4-55 1 0.02 0.49 0.2
187 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19
188 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19
189 INT304104 Il13 Positive_regulation of Positive_regulation of AHR 1 0.14 2.6 0.19
190 INT230749 Crp Regulation of Agtr1a 1 0.07 1.33 0.19
191 INT224086 Binding of Agtr1a and Hspa8 1 0.00 0.1 0.19
192 INT92694 Tgfb1 Positive_regulation of Positive_regulation of Col3a1 1 0.31 0.89 0.19
193 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
194 INT214591 FOXC1 Regulation of ICAM1 1 0.05 0.29 0.19
195 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19
196 INT188921 Binding of Pc and Ahr 1 0.12 0 0.19
197 INT188920 Pc Positive_regulation of Ahr 1 0.14 0 0.18
198 INT184540 Agt Regulation of Gene_expression of Ccl2 1 0.08 1.66 0.18
199 INT41978 Binding of Agt and Htr1a 1 0.41 0.54 0.18
200 INT245183 Binding of CTSB and TCF7L2 1 0.39 6.39 0.18

Single Events

The table below shows the top 100 pain related interactions that have been reported for blood vessel development. They are ordered first by their pain relevance and then by number of times they were reported in blood vessel development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
2 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
3 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
4 INT1158 Regulation of Agt 106 0.61 29.4 30.29
5 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
6 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
7 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
8 INT2066 Localization of Agt 56 0.80 9.95 16.25
9 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
10 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15
11 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
12 INT79703 Gene_expression of Agtr1a 46 0.76 14.18 13.77
13 INT3962 Regulation of AGT 50 0.62 20.96 13.01
14 INT4199 Binding of Agt 76 0.48 21.06 12.66
15 INT90673 Gene_expression of LOX 66 0.65 69.71 12.18
16 INT53038 Positive_regulation of Agtr1a 35 0.67 23.76 11.68
17 INT398 Localization of AGT 45 0.78 16.97 11.54
18 INT8065 Binding of AGT 54 0.48 20.54 10.85
19 INT94004 Negative_regulation of Lox 31 0.59 13.76 10.45
20 INT10982 Negative_regulation of Agtr1a 42 0.58 22.42 10.29
21 INT386 Positive_regulation of Gene_expression of Agt 37 0.70 15.92 8.73
22 INT90674 Negative_regulation of LOX 56 0.57 38.01 8.58
23 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
24 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29
25 INT39301 Gene_expression of Chd7 50 0.26 27.06 8.13
26 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
27 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
28 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
29 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
30 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
31 INT19086 Negative_regulation of COL1A1 32 0.38 16.77 5.98
32 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
33 INT5762 Negative_regulation of Gene_expression of Agt 18 0.57 6.09 5.84
34 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
35 INT65262 Gene_expression of Lox 47 0.74 36.59 5.65
36 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
37 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
38 INT89142 Gene_expression of Lox 28 0.67 15.36 5.2
39 INT84561 Binding of COL1A2 18 0.47 11.76 5.09
40 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77
41 INT37912 Negative_regulation of Chd7 10 0.26 5.84 4.46
42 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
43 INT19965 Positive_regulation of COL1A1 23 0.45 14.49 4.38
44 INT22973 Gene_expression of Col3a1 22 0.42 15.85 4.32
45 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
46 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
47 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
48 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
49 INT53040 Binding of Agtr1a 22 0.47 7.36 4.15
50 INT156137 Gene_expression of Col1a2 28 0.73 13.3 3.99
51 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
52 INT117773 Positive_regulation of Phosphorylation of Ptk2 9 0.69 0.89 3.71
53 INT115921 Positive_regulation of AHR 22 0.49 12.03 3.53
54 INT49238 Protein_catabolism of COL1A2 30 0.97 15.64 3.45
55 INT81229 Binding of COL1A1 24 0.35 12.07 3.3
56 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
57 INT36032 Gene_expression of Col3a1 23 0.72 10.55 3.18
58 INT154233 Negative_regulation of Lox 32 0.56 38.89 3.17
59 INT111195 Negative_regulation of Gene_expression of Agtr1a 7 0.58 3.2 3.16
60 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
61 INT67719 Positive_regulation of Col1a1 21 0.44 8.87 3.12
62 INT164633 Gene_expression of EGFL7 23 0.53 10.46 3.1
63 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
64 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
65 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
66 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
67 INT95105 Gene_expression of TGFBR2 15 0.64 16.36 2.74
68 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
69 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
70 INT138437 Gene_expression of Sphk1 23 0.65 10.01 2.61
71 INT68091 Localization of COL1A1 19 0.66 9.13 2.56
72 INT77852 Binding of Chd7 8 0.31 4.1 2.51
73 INT8890 Transcription of Col1a1 10 0.63 4.02 2.48
74 INT17857 Negative_regulation of Gene_expression of AGT 25 0.46 21.16 2.45
75 INT79261 Positive_regulation of Gene_expression of COL1A1 24 0.36 7.49 2.45
76 INT148071 Gene_expression of Agt 42 0.74 44.9 2.43
77 INT4270 Negative_regulation of Negative_regulation of Agt 10 0.43 1.08 2.43
78 INT63418 Regulation of Agtr1a 8 0.44 3.67 2.43
79 INT163544 Binding of Psen1 40 0.36 15.28 2.42
80 INT96876 Gene_expression of AHR 20 0.77 10.43 2.39
81 INT124862 Gene_expression of Col5a1 4 0.17 2.05 2.32
82 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31
83 INT97152 Protein_catabolism of COL1A1 11 0.74 8.03 2.3
84 INT94002 Regulation of Lox 13 0.38 8.41 2.29
85 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28
86 INT27988 Negative_regulation of Positive_regulation of AGT 11 0.42 5.71 2.27
87 INT61684 Localization of COL1A2 20 0.73 9.31 2.26
88 INT10201 Positive_regulation of Localization of Agt 8 0.50 0.97 2.21
89 INT126513 Gene_expression of Col1a1 23 0.75 10.92 2.18
90 INT89519 Negative_regulation of COL1A2 10 0.36 6.26 2.17
91 INT317583 Positive_regulation of Ppap2b 1 0.09 2.14 2.09
92 INT117457 Positive_regulation of Gene_expression of Lox 9 0.39 6.97 2.08
93 INT12005 Negative_regulation of Localization of Agt 6 0.57 1.49 2.06
94 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05
95 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
96 INT113717 Negative_regulation of Gene_expression of COL1A1 21 0.41 6.14 2.01
97 INT191534 Negative_regulation of EGFL7 10 0.06 7.52 1.98
98 INT79915 Positive_regulation of Agt 27 0.56 12.97 1.96
99 INT12801 Negative_regulation of Regulation of Agt 4 0.43 1.2 1.96
100 INT80798 Positive_regulation of Chd7 16 0.14 7.95 1.95
101 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
102 INT120857 Localization of Col1a1 10 0.71 2.33 1.93
103 INT43944 Negative_regulation of Positive_regulation of Agt 4 0.42 1.44 1.93
104 INT94001 Positive_regulation of Lox 15 0.60 7.46 1.92
105 INT69181 Positive_regulation of Col3a1 10 0.33 5.54 1.91
106 INT152155 Positive_regulation of Col1a2 7 0.56 10.18 1.89
107 INT138439 Positive_regulation of Gene_expression of Sphk1 14 0.48 5.93 1.86
108 INT148326 Gene_expression of Pkd1 7 0.76 5.38 1.85
109 INT154816 Negative_regulation of Sphk1 19 0.41 11.38 1.84
110 INT83596 Gene_expression of Ptk2 6 0.76 2.22 1.84
111 INT96116 Transcription of COL1A1 10 0.44 4.57 1.81
112 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
113 INT96877 Transcription of AHR 7 0.62 3.25 1.77
114 INT134197 Regulation of AHR 11 0.44 4.82 1.76
115 INT15980 Positive_regulation of Positive_regulation of Agt 6 0.50 2.99 1.76
116 INT135568 Localization of CHM 5 0.65 6.51 1.76
117 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
118 INT84375 Regulation of COL1A2 6 0.44 8.75 1.72
119 INT14167 Negative_regulation of Positive_regulation of Ahr 5 0.51 1.54 1.71
120 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7
121 INT12442 Localization of Vegfa 11 0.73 4.85 1.68
122 INT3152 Transcription of Agt 7 0.72 5.09 1.68
123 INT116110 Positive_regulation of PTK2 20 0.66 10.53 1.64
124 INT122597 Transcription of Hif1a 5 0.69 5.56 1.63
125 INT206471 Positive_regulation of Ptk2 34 0.51 25.75 1.61
126 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61
127 INT195230 Negative_regulation of Gene_expression of EGFL7 4 0.08 2.83 1.59
128 INT153723 Negative_regulation of Gene_expression of Hif1a 2 0.41 1.25 1.58
129 INT139317 Negative_regulation of Col1a2 8 0.41 7.17 1.54
130 INT111946 Positive_regulation of Phosphorylation of PTK2 8 0.66 11.5 1.53
131 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
132 INT153201 Negative_regulation of Gene_expression of Col1a1 7 0.38 6.37 1.52
133 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51
134 INT142719 Binding of Col1a1 7 0.34 5.83 1.47
135 INT36389 Binding of AHR 18 0.45 7.22 1.46
136 INT90604 Positive_regulation of Positive_regulation of Ahr 8 0.45 3.52 1.45
137 INT34768 Negative_regulation of Negative_regulation of AGT 10 0.25 2.79 1.42
138 INT54805 Regulation of Ahr 7 0.22 4.14 1.41
139 INT62669 Positive_regulation of COL1A2 13 0.49 6.89 1.4
140 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39
141 INT8067 Negative_regulation of Binding of AGT 12 0.25 10.33 1.39
142 INT71847 Positive_regulation of Positive_regulation of Col3a1 2 0.33 0.61 1.39
143 INT83553 Positive_regulation of Positive_regulation of Agtr1a 3 0.59 4.12 1.37
144 INT22558 Gene_expression of COL3A1 10 0.78 7.22 1.36
145 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
146 INT239215 Binding of Agt 9 0.38 6.75 1.35
147 INT120860 Positive_regulation of Gene_expression of Col1a1 12 0.44 4.84 1.34
148 INT131115 Regulation of Phosphorylation of Ptk2 2 0.61 0.3 1.34
149 INT232785 Localization of Hif1a 8 0.46 10.37 1.33
150 INT3816 Gene_expression of Ahr 13 0.65 7.51 1.31
151 INT11306 Regulation of Gene_expression of Agt 7 0.45 3.29 1.31
152 INT112650 Positive_regulation of Col1a1 3 0.30 5.96 1.3
153 INT172872 Positive_regulation of Lox 12 0.49 12.99 1.29
154 INT221801 Localization of Lox 2 0.24 0.99 1.28
155 INT11241 Transcription of AGT 4 0.52 1.83 1.27
156 INT124861 Positive_regulation of Col5a1 2 0.09 0.75 1.27
157 INT19319 Negative_regulation of Binding of Agt 9 0.42 3.42 1.24
158 INT59473 Negative_regulation of Col1a1 4 0.25 1.33 1.24
159 INT29693 Binding of Ahr 11 0.31 13.27 1.23
160 INT71845 Positive_regulation of Positive_regulation of Col1a1 1 0.34 0.15 1.23
161 INT216380 Gene_expression of PAX6 49 0.78 15.63 1.22
162 INT79916 Negative_regulation of Agt 14 0.47 6 1.22
163 INT84130 Gene_expression of Foxo1 1 0.26 0.97 1.22
164 INT148321 Positive_regulation of Gene_expression of Pkd1 5 0.68 2.93 1.21
165 INT140033 Positive_regulation of Gene_expression of Col1a1 6 0.14 3.68 1.2
166 INT39711 Negative_regulation of FOXC1 4 0.41 4.29 1.2
167 INT47644 Positive_regulation of Localization of AGT 4 0.45 1.24 1.2
168 INT87343 Negative_regulation of Phosphorylation of PTK2 34 0.59 18.38 1.19
169 INT138434 Positive_regulation of Sphk1 10 0.48 2.18 1.18
170 INT81311 Gene_expression of FOXC1 9 0.44 3.46 1.18
171 INT137607 Positive_regulation of Localization of Vegfa 7 0.49 3.72 1.18
172 INT87346 Binding of PTK2 6 0.37 4.03 1.18
173 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18
174 INT164634 Regulation of EGFL7 4 0.09 3.06 1.15
175 INT28594 Positive_regulation of Transcription of Agt 2 0.47 1.3 1.15
176 INT115621 Positive_regulation of Binding of AGT 1 0.02 0 1.15
177 INT148072 Gene_expression of Agtr1a 5 0.75 9.41 1.13
178 INT101104 Positive_regulation of Gene_expression of COL1A2 12 0.69 5.87 1.09
179 INT156427 Localization of FOXC1 2 0.73 1.36 1.07
180 INT263822 Positive_regulation of Gene_expression of LOX 8 0.50 11 1.06
181 INT87342 Regulation of Phosphorylation of PTK2 3 0.59 5.7 1.05
182 INT67097 Gene_expression of MIB1 20 0.75 21.06 1.03
183 INT86889 Gene_expression of Cdx2 8 0.60 4.23 1.02
184 INT133102 Negative_regulation of Gene_expression of COL1A2 8 0.08 2.56 1.02
185 INT45079 Binding of Ahr 21 0.44 10.07 1
186 INT280495 Regulation of PPAP2B 1 0.06 1.64 1
187 INT214609 Positive_regulation of Gene_expression of FOXC1 1 0.08 1.78 1
188 INT37914 Regulation of Negative_regulation of Chd7 1 0.12 0 1
189 INT156614 Regulation of Gene_expression of COL1A1 6 0.33 2.51 0.99
190 INT46334 Binding of FOXC1 2 0.36 2.66 0.99
191 INT43131 Regulation of FOXC1 3 0.36 1.09 0.98
192 INT129997 Protein_catabolism of Col1a1 5 0.96 3.43 0.96
193 INT13696 Regulation of COL3A1 2 0.45 2.97 0.95
194 INT155867 Transcription of COL1A2 8 0.69 2.9 0.94
195 INT21660 Regulation of CHM 14 0.61 8.51 0.93
196 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
197 INT204547 Positive_regulation of Gene_expression of Col1a2 2 0.04 2.08 0.91
198 INT172868 Regulation of Lox 5 0.43 5.76 0.9
199 INT87344 Gene_expression of PTK2 90 0.78 59.03 0.87
200 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
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