GO:0001569

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Name patterning of blood vessels
Categary Process
Go Slim No
Go Link GO:0001569
Unique Molecular Interactions 1230
Total Molecular Interactions 1900
Total Single Events 12828
Pain Genes Associated 47

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for patterning of blood vessels. They are ordered first by their pain relevance and then by number of times they were reported for patterning of blood vessels. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17
3 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
4 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
5 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
6 INT334532 Sema3a Negative_regulation of Gene_expression of Nrp1 1 0.19 7.58 2
7 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
8 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
9 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
10 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
11 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69
12 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
13 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
14 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
15 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
16 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
17 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
18 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
19 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
20 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
21 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
22 INT149844 Negative_regulation of Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.26
23 INT149845 Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.24
24 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
25 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
26 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
27 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
28 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
29 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
30 INT172500 Ednra Positive_regulation of Coc 1 0.01 1 1.2
31 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
32 INT31444 ENG Positive_regulation of Prl 1 0.01 0 1.14
33 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
34 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
35 INT107938 POMC Positive_regulation of Gene_expression of TGFBR2 1 0.42 1.09 1.07
36 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
37 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
38 INT134213 CRH Positive_regulation of Gene_expression of ENG 1 0.13 0.61 1.03
39 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
40 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97
41 INT275409 Binding of ITIH4 and Cxcr4 1 0.09 2.87 0.97
42 INT275386 Binding of Cxcr4 and Htatsf1 1 0.01 3.25 0.97
43 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
44 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
45 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
46 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
47 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
48 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
49 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
50 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
51 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
52 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
53 INT123023 Ednra Regulation of Adarb1 1 0.00 0 0.93
54 INT123024 Csf2 Regulation of Ednra 1 0.06 0 0.92
55 INT32187 Binding of ENG and Negative_regulation of Localization of LH 1 0.01 0 0.91
56 INT166135 Regulation of Binding of Cxcl12 and Cxcr4 1 0.30 0.9 0.91
57 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91
58 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
59 INT254004 Cxcl12 Positive_regulation of Cxcr4 1 0.47 1.29 0.86
60 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
61 INT253995 Binding of Cxcl12 and Cyp3a23/3a1 1 0.06 1.28 0.85
62 INT128701 Ednra Regulation of EDNRB 1 0.17 0.58 0.84
63 INT128702 Ednra Regulation of EDNRA 1 0.00 0.58 0.84
64 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
65 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
66 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
67 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
68 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
69 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
70 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82
71 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
72 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
73 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81
74 INT157918 TRPV1 Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
75 INT107937 POMC Regulation of Gene_expression of TGFBR2 1 0.28 0.82 0.81
76 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
77 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
78 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
79 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
80 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
81 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
82 INT148909 Binding of GNA13 and TP53INP2 1 0.06 0.31 0.73
83 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
84 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
85 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
86 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
87 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
88 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
89 INT260832 Binding of NRP2 and Nrp1 1 0.00 2.32 0.7
90 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
91 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
92 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
93 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
94 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
95 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
96 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
97 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
98 INT134286 PLD2 Regulation of Regulation of EDNRA 1 0.10 0 0.67
99 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
100 INT313698 Binding of Calca and Edn1 1 0.30 0 0.65
101 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
102 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65
103 INT32719 ENG Regulation of LH 2 0.00 0 0.64
104 INT31443 ENG Positive_regulation of Localization of Pomc 1 0.00 0 0.63
105 INT219921 EDNRA Negative_regulation of Trpv1 1 0.13 0.36 0.63
106 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
107 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
108 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
109 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
110 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
111 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
112 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61
113 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61
114 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
115 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
116 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61
117 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6
118 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6
119 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6
120 INT131642 Edn1 Positive_regulation of Positive_regulation of Insrr 1 0.01 0.44 0.6
121 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
122 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59
123 INT130162 Pomc Positive_regulation of Gene_expression of Edn1 1 0.25 0 0.58
124 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
125 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58
126 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57
127 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
128 INT260845 Binding of Flt1 and Positive_regulation of Gene_expression of TNF 1 0.36 1.5 0.56
129 INT253998 Cyp3a23/3a1 Positive_regulation of Binding of Cxcl12 1 0.10 0.65 0.55
130 INT253990 Cyp3a23/3a1 Positive_regulation of Cxcl12 1 0.09 0.65 0.55
131 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
132 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
133 INT62597 Binding of Edn1 and Vip 1 0.23 0.79 0.54
134 INT105110 Cxcl12 Positive_regulation of NFKB1 1 0.06 0.54 0.53
135 INT55445 Positive_regulation of Ahr Regulation of Mme 1 0.23 0 0.53
136 INT143853 Ngf Positive_regulation of Nfatc4 1 0.02 0.62 0.53
137 INT134214 CRH Regulation of Localization of ENG 1 0.14 0.39 0.53
138 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53
139 INT105108 Negative_regulation of Cxcl12 Positive_regulation of NFKB1 1 0.05 0.54 0.53
140 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 0.56 0.15 0.53
141 INT130160 Pomc Regulation of Edn1 1 0.25 0 0.53
142 INT143855 Ngf Regulation of Positive_regulation of Nfatc4 1 0.02 0.62 0.53
143 INT32151 ENG Positive_regulation of Gene_expression of IFNA1 1 0.37 0 0.53
144 INT32291 ENG Negative_regulation of LH 2 0.00 0 0.52
145 INT147576 Positive_regulation of Ahr Positive_regulation of Gene_expression of Scrg1 1 0.00 0.17 0.52
146 INT275388 Binding of Lamp1 and Cxcr4 1 0.01 1.45 0.52
147 INT275403 Binding of Cxcr4 and GOLPH3 1 0.00 1.45 0.52
148 INT194918 Csf2 Positive_regulation of Gene_expression of VEGFA 1 0.02 0.85 0.52
149 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
150 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
151 INT162503 AHR Regulation of CYP1A2 3 0.61 0.18 0.5
152 INT30618 Slc3a1 Regulation of ENG 1 0.00 0 0.5
153 INT30619 Pomc Regulation of ENG 1 0.00 0 0.5
154 INT127430 VEGFA Negative_regulation of Gene_expression of TIMP1 1 0.43 0.6 0.5
155 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
156 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49
157 INT94015 Binding of EDN1 and INSRR 1 0.04 0 0.49
158 INT102214 ENG Negative_regulation of HP 1 0.01 0 0.49
159 INT60872 Binding of ENG and Abat 1 0.00 0 0.49
160 INT94024 Binding of EDN1 and EDN3 1 0.27 0 0.49
161 INT60871 ENG Regulation of Localization of LH 1 0.00 0 0.49
162 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49
163 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49
164 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
165 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
166 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48
167 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48
168 INT112843 Binding of OPRK1 and Nfatc4 1 0.00 0 0.48
169 INT99571 Edn1 Positive_regulation of Localization of Ednra 1 0.01 0.32 0.47
170 INT331928 Negative_regulation of Cpox Negative_regulation of VEGFA 1 0.01 0.97 0.47
171 INT43695 ENG Regulation of Regulation of Prl 1 0.00 0 0.47
172 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
173 INT60870 ENG Negative_regulation of Localization of LH 1 0.00 0 0.47
174 INT260843 Il6 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
175 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
176 INT102213 Binding of ENG and HP 1 0.01 0 0.47
177 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
178 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
179 INT224698 Il17a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
180 INT275399 Binding of ERVW-1 and Cxcr4 1 0.00 1.73 0.46
181 INT224699 Il18 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
182 INT50497 Edn1 Positive_regulation of Pla2g1b 1 0.01 0.23 0.45
183 INT224451 Il1 Positive_regulation of Gene_expression of VEGFA 1 0.10 1.08 0.45
184 INT110475 EDN1 Regulation of PRKCA 1 0.05 0.07 0.45
185 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
186 INT94093 Pnoc Positive_regulation of EDNRA 1 0.03 0.1 0.44
187 INT281126 Binding of Ccr2 and Cxcr4 1 0.30 0.32 0.44
188 INT115914 AHR Regulation of Gene_expression of PPIG 1 0.25 0.36 0.44
189 INT253996 Binding of Cxcr2 and Cxcr4 1 0.18 0.81 0.44
190 INT224434 TNF Positive_regulation of VEGFA 1 0.10 2.04 0.44
191 INT115916 AHR Regulation of Gene_expression of SLC45A2 1 0.64 0.36 0.44
192 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43
193 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43
194 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
195 INT115915 AHR Regulation of Gene_expression of CYP2B6 1 0.06 0.36 0.43
196 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42
197 INT313704 Smn1 Negative_regulation of Gene_expression of Edn1 1 0.32 0 0.42
198 INT202516 Positive_regulation of Binding of ENG and Penk 1 0.03 0.58 0.42
199 INT202515 Binding of ENG and Penk 1 0.02 0.57 0.41
200 INT153720 Binding of VEGFA and Pscs 1 0.32 3.12 0.41

Single Events

The table below shows the top 100 pain related interactions that have been reported for patterning of blood vessels. They are ordered first by their pain relevance and then by number of times they were reported in patterning of blood vessels. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
3 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
4 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
5 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
6 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
7 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6
8 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
9 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69
10 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
11 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
12 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
13 INT10799 Localization of ENG 63 0.78 18.67 27.28
14 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67
15 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
16 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
17 INT96741 Gene_expression of Cxcr4 62 0.78 32.3 22.14
18 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
19 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
20 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
21 INT5048 Binding of Edn1 55 0.47 18.86 19.16
22 INT6728 Gene_expression of Ednra 43 0.65 13.41 17.38
23 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
24 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
25 INT9191 Localization of EDN1 94 0.81 57.01 14.78
26 INT7674 Regulation of ENG 42 0.30 11.41 14.44
27 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
28 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
29 INT6365 Localization of Edn1 56 0.81 18.84 13.83
30 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
31 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79
32 INT222233 Gene_expression of Cxcl12 42 0.69 32.64 10.13
33 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
34 INT6361 Localization of Edn1 30 0.81 19.09 9.7
35 INT149069 Positive_regulation of Cxcr4 24 0.68 12.21 9.54
36 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86
37 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79
38 INT6727 Positive_regulation of Ednra 27 0.64 18.75 8.71
39 INT7673 Negative_regulation of ENG 31 0.42 7.9 8.61
40 INT10237 Binding of EDN1 40 0.48 16 8.48
41 INT30382 Negative_regulation of Ednra 21 0.42 12.06 8.19
42 INT126478 Gene_expression of Cxcl12 78 0.77 58.69 8.01
43 INT77804 Regulation of Ednra 9 0.39 2.71 7.94
44 INT54978 Binding of EDNRA 36 0.41 14.97 7.86
45 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
46 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
47 INT67170 Gene_expression of Ednra 22 0.65 9.35 7.57
48 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
49 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27
50 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
51 INT167049 Binding of Ednra 3 0.07 3.47 6.84
52 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
53 INT23375 Binding of ENG 17 0.47 6.02 6.46
54 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
55 INT126481 Gene_expression of Cxcr4 69 0.77 34.99 6
56 INT253974 Binding of Cxcr4 22 0.47 12.26 5.95
57 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
58 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
59 INT96744 Positive_regulation of Gene_expression of Cxcr4 14 0.68 7.92 5.75
60 INT136309 Positive_regulation of Cxcl12 24 0.62 12.45 5.58
61 INT70907 Negative_regulation of EDNRA 30 0.36 19.68 5.49
62 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36
63 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
64 INT92858 Negative_regulation of Ednra 6 0.57 1.25 4.81
65 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
66 INT17803 Regulation of Edn1 14 0.54 4.75 4.71
67 INT246315 Localization of Ednra 22 0.15 2.73 4.64
68 INT21953 Binding of Ednra 12 0.33 4.72 4.56
69 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
70 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
71 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
72 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
73 INT100372 Gene_expression of Flt1 47 0.71 24.33 4.09
74 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
75 INT75485 Gene_expression of Tgfbr2 10 0.57 10.98 3.76
76 INT253983 Binding of Cxcl12 8 0.43 5.33 3.71
77 INT115921 Positive_regulation of AHR 22 0.49 12.03 3.53
78 INT15844 Positive_regulation of Localization of ENG 7 0.67 4.2 3.47
79 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42
80 INT115203 Negative_regulation of Positive_regulation of Ednra 5 0.33 1.27 3.32
81 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
82 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
83 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
84 INT96740 Transcription of Cxcr4 6 0.68 2.96 3.12
85 INT49971 Regulation of Ednra 10 0.35 2.4 3.06
86 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
87 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
88 INT53374 Binding of Edn1 17 0.43 11.66 2.98
89 INT32222 Negative_regulation of Gene_expression of ENG 9 0.37 2.23 2.89
90 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
91 INT93058 Positive_regulation of Gene_expression of Ednra 8 0.28 4.11 2.88
92 INT113041 Gene_expression of IHH 9 0.78 5.83 2.87
93 INT181386 Positive_regulation of Cxcl12 12 0.69 15.35 2.84
94 INT248177 Localization of Cxcr4 17 0.79 4.87 2.82
95 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
96 INT95105 Gene_expression of TGFBR2 15 0.64 16.36 2.74
97 INT76836 Positive_regulation of Ednra 6 0.55 2.65 2.72
98 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71
99 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
100 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
101 INT22071 Positive_regulation of Gene_expression of ENG 13 0.50 5.44 2.62
102 INT253982 Positive_regulation of Binding of Cxcl12 1 0.45 3.85 2.6
103 INT149068 Regulation of Cxcr4 3 0.44 3.77 2.46
104 INT110231 Regulation of Gene_expression of Cxcr4 7 0.44 3.18 2.44
105 INT130638 Regulation of Cxcl12 6 0.34 2.91 2.44
106 INT113164 Regulation of Regulation of VEGFA 6 0.36 5.96 2.43
107 INT96876 Gene_expression of AHR 20 0.77 10.43 2.39
108 INT13997 Regulation of Gene_expression of ENG 11 0.36 3.31 2.31
109 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31
110 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28
111 INT240113 Gene_expression of Nrp1 11 0.30 10.88 2.24
112 INT12133 Regulation of Localization of ENG 3 0.03 0.57 2.24
113 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21
114 INT176088 Gene_expression of Tek 39 0.65 14.25 2.19
115 INT222230 Positive_regulation of Gene_expression of Cxcl12 11 0.59 5.26 2.13
116 INT49253 Regulation of Gene_expression of EDN1 11 0.61 3.92 2.07
117 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05
118 INT156677 Regulation of Gene_expression of Ednra 4 0.15 0.25 2.05
119 INT100371 Positive_regulation of Flt1 11 0.63 6.42 2.02
120 INT297679 Positive_regulation of Gene_expression of Cxcl12 6 0.69 8.02 2.02
121 INT136818 Positive_regulation of Phosphorylation of VEGFA 4 0.46 0.81 2.02
122 INT126060 Negative_regulation of Gene_expression of Cxcr4 9 0.42 3.14 1.99
123 INT32135 Positive_regulation of Positive_regulation of ENG 2 0.02 0.98 1.99
124 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
125 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
126 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
127 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92
128 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92
129 INT226637 Negative_regulation of Cxcr4 41 0.48 24.42 1.91
130 INT76834 Negative_regulation of Gene_expression of Edn1 4 0.43 1.76 1.88
131 INT79815 Positive_regulation of Localization of Edn1 7 0.68 2.07 1.79
132 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
133 INT96877 Transcription of AHR 7 0.62 3.25 1.77
134 INT134197 Regulation of AHR 11 0.44 4.82 1.76
135 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76
136 INT173700 Negative_regulation of Binding of Edn1 2 0.58 0.41 1.76
137 INT126476 Positive_regulation of Cxcr4 25 0.69 19.01 1.72
138 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
139 INT113676 Gene_expression of NRP1 22 0.72 10.81 1.71
140 INT14167 Negative_regulation of Positive_regulation of Ahr 5 0.51 1.54 1.71
141 INT15845 Negative_regulation of Localization of ENG 3 0.05 0.76 1.71
142 INT253972 Positive_regulation of Positive_regulation of Cxcl12 1 0.45 3.22 1.71
143 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7
144 INT12442 Localization of Vegfa 11 0.73 4.85 1.68
145 INT14842 Negative_regulation of Binding of EDN1 4 0.57 0.67 1.66
146 INT255663 Binding of Flt1 11 0.32 6.92 1.64
147 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
148 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61
149 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
150 INT222227 Localization of Cxcl12 5 0.64 1.61 1.59
151 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
152 INT72021 Localization of Ednra 7 0.58 3.13 1.53
153 INT181579 Phosphorylation of Edn1 1 0.71 8.59 1.51
154 INT89116 Regulation of Positive_regulation of VEGFA 8 0.43 6.62 1.5
155 INT254252 Localization of Cxcl12 9 0.76 7.17 1.49
156 INT15407 Positive_regulation of Positive_regulation of Edn1 5 0.62 3.69 1.49
157 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48
158 INT65640 Positive_regulation of Localization of Edn1 2 0.42 2.16 1.48
159 INT182629 Binding of Cxcr4 12 0.36 5.24 1.47
160 INT23938 Positive_regulation of Gene_expression of EDNRA 8 0.45 9.82 1.47
161 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
162 INT36389 Binding of AHR 18 0.45 7.22 1.46
163 INT90604 Positive_regulation of Positive_regulation of Ahr 8 0.45 3.52 1.45
164 INT129488 Regulation of Gene_expression of EDNRA 5 0.51 3.39 1.44
165 INT54805 Regulation of Ahr 7 0.22 4.14 1.41
166 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39
167 INT199550 Negative_regulation of Flt1 18 0.37 12.57 1.37
168 INT100373 Negative_regulation of Gene_expression of Flt1 11 0.53 10 1.37
169 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
170 INT3816 Gene_expression of Ahr 13 0.65 7.51 1.31
171 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
172 INT178494 Gene_expression of Angpt1 10 0.37 9.77 1.28
173 INT32717 Negative_regulation of Regulation of ENG 3 0.00 0.43 1.25
174 INT90938 Gene_expression of Eng 48 0.72 15.76 1.24
175 INT29693 Binding of Ahr 11 0.31 13.27 1.23
176 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
177 INT137607 Positive_regulation of Localization of Vegfa 7 0.49 3.72 1.18
178 INT17802 Transcription of Edn1 6 0.24 6.31 1.18
179 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18
180 INT140983 Gene_expression of Ihh 7 0.78 2.06 1.15
181 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
182 INT51863 Negative_regulation of Negative_regulation of ENG 2 0.04 0.51 1.13
183 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12
184 INT134627 Positive_regulation of Gene_expression of Flt1 9 0.49 7.16 1.12
185 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
186 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
187 INT149553 Negative_regulation of Transcription of Cxcr4 2 0.36 0.29 1.06
188 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
189 INT211294 Binding of Cxcl12 4 0.45 2.89 1.05
190 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
191 INT10448 Positive_regulation of Srf 3 0.47 0.89 1.03
192 INT135032 Negative_regulation of SRF 1 0.49 0 1.03
193 INT45079 Binding of Ahr 21 0.44 10.07 1
194 INT134274 Positive_regulation of Nfatc4 2 0.47 0.7 1
195 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99
196 INT69803 Regulation of Localization of Edn1 3 0.62 0.79 0.98
197 INT72024 Localization of EDNRA 11 0.57 8.22 0.96
198 INT76835 Negative_regulation of Gene_expression of Ednra 2 0.10 0.89 0.96
199 INT253976 Positive_regulation of Positive_regulation of Cxcr4 1 0.46 1.19 0.96
200 INT49255 Protein_catabolism of EDN1 5 0.99 2.66 0.95
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