GO:0001578

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Name microtubule bundle formation
Categary Process
Go Slim No
Go Link GO:0001578
Unique Molecular Interactions 99
Total Molecular Interactions 143
Total Single Events 2042
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for microtubule bundle formation. They are ordered first by their pain relevance and then by number of times they were reported for microtubule bundle formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT284860 Binding of Pdzd2 and Nav1 9 0.29 2.33 2.34
2 INT128778 Binding of Mcam and Nav1 1 0.03 0.51 2.28
3 INT128777 Binding of Cntn1 and Nav1 1 0.48 0.51 2.28
4 INT185097 NGF Regulation of Gene_expression of NAV1 1 0.61 0.81 1.85
5 INT317184 BMS1 Regulation of Gene_expression of NAV1 1 0.03 1.94 1.62
6 INT334633 Binding of Cntnap1 and Nav1 1 0.10 1.36 1.48
7 INT131949 ANTXR1 Positive_regulation of NAV1 1 0.03 0.23 1.38
8 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3
9 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
10 INT220752 Negative_regulation of EGF Regulation of NAV1 1 0.26 0 1.18
11 INT220748 EGF Regulation of NAV1 1 0.28 0 1.17
12 INT134870 Regulation of Binding of Calm3 and Nav1 1 0.17 0.42 1.1
13 INT134869 Binding of Calm3 and Nav1 1 0.31 0.42 1.1
14 INT119744 Binding of BHLHE22 and NAV1 1 0.29 0.49 1.09
15 INT83936 Binding of Mtap2 and Penk 1 0.22 0.19 1.07
16 INT346204 Binding of S100A10 and TPPP 1 0.02 1.62 0.97
17 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
18 INT284855 Binding of S100a10 and Nav1 4 0.21 0.99 0.88
19 INT220739 EGF Positive_regulation of Transcription of NAV1 1 0.31 0.16 0.83
20 INT154193 Binding of KCNK2 and Mtap2 1 0.22 0.48 0.74
21 INT355815 BACE1 Regulation of Positive_regulation of NAV1 1 0.32 0.26 0.72
22 INT355814 BACE1 Regulation of Gene_expression of NAV1 1 0.37 0.24 0.72
23 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
24 INT352284 Dmbx1 Regulation of Nav1 1 0.26 0 0.59
25 INT119747 NAV1 Regulation of Gene_expression of BHLHE22 1 0.31 0.26 0.53
26 INT346205 Binding of CD74 and TPPP 1 0.02 0.87 0.51
27 INT102599 Binding of EXOSC3 and TPPP3 3 0.39 2.61 0.48
28 INT116227 Pnoc Negative_regulation of NAV1 1 0.02 0.1 0.48
29 INT355817 BACE1 Regulation of NAV1 1 0.37 0.7 0.45
30 INT306693 Prkca Regulation of Positive_regulation of Nav1 1 0.10 0.06 0.39
31 INT168200 Binding of CA1 and Nav1 1 0.11 0 0.39
32 INT235880 Binding of Mtap2 and Prkaca 1 0.07 0.41 0.38
33 INT355816 GNPTAB Regulation of NAV1 1 0.01 0.37 0.38
34 INT306694 Nav1 Positive_regulation of Gene_expression of Scn7a 1 0.01 0.07 0.38
35 INT306692 Prkaca Regulation of Positive_regulation of Nav1 1 0.13 0.06 0.35
36 INT342687 Pdzd2 Regulation of Gene_expression of Nav1 1 0.19 0.3 0.35
37 INT342691 Pdzd2 Regulation of Nav1 1 0.19 0.48 0.34
38 INT346226 Binding of TPPP and Braf 1 0.06 0.6 0.33
39 INT220740 EGF Positive_regulation of Regulation of NAV1 1 0.31 0.61 0.32
40 INT149948 Ephb1 Negative_regulation of Phosphorylation of Map2 1 0.37 0.07 0.25
41 INT236005 Positive_regulation of MAPK1 Positive_regulation of Binding of Map2 1 0.04 0 0.25
42 INT236004 Positive_regulation of MAPK1 Positive_regulation of Phosphorylation of Map2 1 0.04 0 0.24
43 INT230269 Negative_regulation of Binding of NA and Nav1 1 0.00 0 0.19
44 INT230270 Binding of NA and Nav1 1 0.00 0 0.19
45 INT284857 S100a10 Positive_regulation of Gene_expression of Nav1 1 0.16 0.3 0.17
46 INT352283 Binding of Dmbx1 and Nav1 1 0.24 0 0.16
47 INT284861 S100a10 Positive_regulation of Localization of Nav1 1 0.17 0.07 0.14
48 INT342688 Binding of Cap1 and Nav1 1 0.00 0.19 0.14
49 INT278423 Binding of Emp1 and Map2 1 0.06 0.46 0.12
50 INT284854 Pdzd2 Positive_regulation of Gene_expression of Nav1 1 0.42 0 0.11
51 INT231223 Binding of KCNQ1 and Nav1 1 0.03 0.59 0.11
52 INT214014 Binding of Dysf and Nav1 1 0.00 0.5 0.1
53 INT342692 Binding of Gopc and Nav1 1 0.02 0.15 0.1
54 INT214012 Binding of Ank1 and Nav1 1 0.01 0.51 0.1
55 INT214011 Negative_regulation of Binding of Ank1 and Nav1 1 0.01 0.51 0.1
56 INT239980 Ts3 Regulation of Nav1 1 0.12 0 0.09
57 INT293471 Binding of Map2 and Fig4 1 0.03 0 0.08
58 INT261386 Nsdhl Positive_regulation of Map2 1 0.08 0.59 0.07
59 INT207629 Binding of Mtap1b and Cabp1 1 0.30 0 0.06
60 INT310496 Binding of Neurog2 and Mtap2 1 0.17 0.44 0.05
61 INT343498 Binding of ITIH4 and TPPP 1 0.06 0.64 0.05
62 INT300972 Mtap2 Regulation of Coq10a 1 0.24 0.37 0.04
63 INT313273 Binding of GRIN1 and MAP2 1 0.16 0.79 0.04
64 INT207644 Binding of Car2 and Mtap1b 1 0.04 0 0.03
65 INT308748 TPPP Regulation of MIR1-1 1 0.04 0.13 0.03
66 INT204479 Fmr1 Negative_regulation of Mtap1b 1 0.23 0.68 0
67 INT204495 Fmr1 Negative_regulation of Transcription of Mtap1b 1 0.22 0.68 0
68 INT204178 Binding of IFI27 and TPPP 1 0.02 0.35 0
69 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0
70 INT204474 Fmr1 Negative_regulation of Transcription of Map1b 1 0.41 0.68 0
71 INT261840 Binding of Mtap7 and Trpv4 1 0.05 0.12 0
72 INT66342 LIF Positive_regulation of Phosphorylation of CLIP1 1 0.60 1.57 0
73 INT265265 SCN5A Regulation of Gene_expression of NAV1 1 0.01 0.16 0
74 INT271997 Binding of Cdk1 and Plk1 1 0.03 0.3 0
75 INT115240 Binding of Casp1 and TPPP3 1 0.52 0.11 0
76 INT274622 Binding of CLIP1 and Amph 1 0.40 0 0
77 INT249822 Foxm1 Positive_regulation of Transcription of Plk1 1 0.50 0.12 0
78 INT204475 Fmr1 Negative_regulation of Map1b 1 0.41 0.68 0
79 INT274581 Binding of CLIP1 and BFAR 1 0.15 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for microtubule bundle formation. They are ordered first by their pain relevance and then by number of times they were reported in microtubule bundle formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75
2 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46
3 INT129303 Positive_regulation of NAV1 54 0.70 36.92 57.45
4 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33
5 INT111051 Negative_regulation of Nav1 64 0.59 25.51 47.27
6 INT103261 Positive_regulation of Nav1 68 0.70 24.25 39.27
7 INT116321 Regulation of Nav1 38 0.62 26.62 37.97
8 INT131413 Positive_regulation of Gene_expression of NAV1 35 0.70 17.5 36.83
9 INT111052 Positive_regulation of Gene_expression of Nav1 44 0.70 18.98 35.28
10 INT103262 Localization of Nav1 53 0.81 19.23 34.44
11 INT123419 Binding of NAV1 37 0.48 7.09 26.43
12 INT136268 Localization of NAV1 22 0.75 2.84 26.23
13 INT116226 Regulation of NAV1 20 0.51 14.32 25.61
14 INT111050 Negative_regulation of Gene_expression of Nav1 23 0.58 5.97 17.06
15 INT113384 Regulation of Gene_expression of Nav1 20 0.62 8.57 16.15
16 INT114507 Negative_regulation of Gene_expression of NAV1 17 0.43 7.24 15.93
17 INT112207 Binding of Nav1 27 0.47 7.1 15.43
18 INT137043 Transcription of NAV1 16 0.72 6.98 12.12
19 INT149518 Regulation of Gene_expression of NAV1 7 0.62 6.73 9.62
20 INT306287 Binding of TPPP 4 0.24 14.81 7.71
21 INT113376 Transcription of Nav1 7 0.69 0.93 6.36
22 INT111049 Negative_regulation of Positive_regulation of Nav1 5 0.43 4.39 6.25
23 INT167435 Positive_regulation of Transcription of NAV1 3 0.70 4.56 5.86
24 INT75629 Gene_expression of Mtap2 41 0.66 8.19 4.51
25 INT355819 Protein_catabolism of NAV1 1 0.71 1.21 4.21
26 INT106972 Gene_expression of MAP2 36 0.75 9.72 3.87
27 INT111053 Positive_regulation of Positive_regulation of Nav1 4 0.46 2.97 3.53
28 INT102516 Gene_expression of Map2 29 0.69 6.73 3.41
29 INT59288 Negative_regulation of Map2 12 0.59 6.2 3.19
30 INT113385 Negative_regulation of Transcription of Nav1 2 0.43 0.73 2.74
31 INT113375 Positive_regulation of Negative_regulation of Nav1 4 0.50 0.67 2.56
32 INT204185 Gene_expression of TPPP 7 0.22 6.48 2.54
33 INT35390 Phosphorylation of Map2 12 0.81 2.06 2.47
34 INT342684 Phosphorylation of Nav1 2 0.68 0.23 2.37
35 INT232473 Positive_regulation of Binding of NAV1 1 0.69 1.35 2.31
36 INT317185 Positive_regulation of Positive_regulation of NAV1 1 0.47 1.51 2.08
37 INT131950 Negative_regulation of Positive_regulation of NAV1 2 0.31 0.22 1.99
38 INT71569 Protein_catabolism of Map2 4 1.00 2.8 1.92
39 INT89618 Positive_regulation of Map1b 1 0.68 2.48 1.81
40 INT115850 Localization of Mtap2 10 0.73 3.68 1.76
41 INT151323 Positive_regulation of MAP2 7 0.50 1.36 1.71
42 INT245656 Positive_regulation of Gene_expression of Mtap2 4 0.37 3.5 1.71
43 INT149944 Positive_regulation of Phosphorylation of Map2 7 0.69 1.09 1.68
44 INT278538 Negative_regulation of Negative_regulation of NAV1 2 0.42 0.84 1.56
45 INT113377 Positive_regulation of Localization of Nav1 2 0.70 0.23 1.46
46 INT73673 Negative_regulation of Mtap2 9 0.32 8.25 1.4
47 INT162284 Binding of Map2 3 0.29 1.78 1.35
48 INT134866 Negative_regulation of Binding of Nav1 1 0.42 0.38 1.33
49 INT116320 Regulation of Positive_regulation of Nav1 2 0.19 0.19 1.29
50 INT355824 Positive_regulation of Localization of NAV1 1 0.43 0.26 1.27
51 INT69053 Regulation of Map2 3 0.27 2.3 1.17
52 INT296809 Negative_regulation of Negative_regulation of Nav1 4 0.38 1.33 1.1
53 INT247613 Negative_regulation of Regulation of NAV1 1 0.09 0.78 1.07
54 INT355825 Positive_regulation of Protein_catabolism of NAV1 1 0.36 0.72 1
55 INT195981 Transcription of Mtap2 1 0.52 0.53 0.99
56 INT122073 Regulation of Regulation of Nav1 2 0.44 0.75 0.96
57 INT151324 Transcription of MAP2 2 0.44 0.49 0.95
58 INT106746 Gene_expression of Mtap7 1 0.39 2.09 0.95
59 INT122301 Positive_regulation of Map2 5 0.44 1.38 0.92
60 INT151320 Positive_regulation of Transcription of MAP2 1 0.31 0.49 0.86
61 INT284844 Regulation of Localization of Nav1 2 0.59 0.18 0.83
62 INT309305 Regulation of Negative_regulation of NAV1 1 0.26 0 0.77
63 INT254017 Negative_regulation of Gene_expression of Map2 3 0.48 0.93 0.74
64 INT230717 Positive_regulation of Negative_regulation of NAV1 1 0.42 0.48 0.73
65 INT204180 Positive_regulation of TPPP 4 0.16 3.54 0.71
66 INT89621 Gene_expression of Map1b 1 0.76 1.48 0.7
67 INT355822 Negative_regulation of Localization of NAV1 1 0.27 0 0.64
68 INT116225 Positive_regulation of Regulation of NAV1 1 0.03 0.09 0.64
69 INT49460 Positive_regulation of TPPP3 1 0.67 0 0.59
70 INT49461 Positive_regulation of Positive_regulation of TPPP3 1 0.45 0 0.59
71 INT71568 Regulation of Protein_catabolism of Map2 1 0.45 0.8 0.58
72 INT116319 Positive_regulation of Regulation of Nav1 2 0.19 0.09 0.57
73 INT173429 Phosphorylation of NAV1 1 0.61 0.05 0.57
74 INT35389 Negative_regulation of Phosphorylation of Map2 3 0.44 0.25 0.56
75 INT216371 Positive_regulation of Gene_expression of MAP2 3 0.22 0.12 0.45
76 INT115753 Regulation of Negative_regulation of Nav1 3 0.38 0 0.44
77 INT235842 Phosphorylation of Mtap2 2 0.52 0.94 0.44
78 INT154190 Binding of Mtap2 3 0.31 0.31 0.43
79 INT341334 Negative_regulation of Localization of Nav1 1 0.41 0.22 0.42
80 INT98419 Positive_regulation of Mtap7 3 0.38 2.66 0.41
81 INT91662 Localization of TPPP3 1 0.68 0.2 0.37
82 INT278419 Localization of Map2 3 0.58 1.21 0.36
83 INT89619 Phosphorylation of Map1b 2 0.54 1.06 0.35
84 INT329030 Positive_regulation of Gene_expression of Map2 1 0.57 0.27 0.33
85 INT217380 Negative_regulation of Negative_regulation of Mtap2 2 0.27 1.18 0.31
86 INT235993 Positive_regulation of Binding of Map2 1 0.14 0 0.25
87 INT1475 Localization of CLIP1 1 0.06 0 0.24
88 INT202338 Positive_regulation of Mtap2 6 0.32 1.11 0.23
89 INT137044 Negative_regulation of Transcription of NAV1 1 0.13 0.23 0.23
90 INT149946 Regulation of Phosphorylation of Map2 1 0.61 0.07 0.22
91 INT123418 Negative_regulation of Binding of NAV1 1 0.43 0 0.22
92 INT245664 Negative_regulation of Gene_expression of Mtap2 1 0.27 0.41 0.2
93 INT207621 Regulation of Mtap1b 3 0.35 0.15 0.19
94 INT220606 Protein_catabolism of Nav1 1 0.61 0 0.19
95 INT220573 Positive_regulation of Protein_catabolism of Nav1 1 0.34 0 0.19
96 INT171218 Gene_expression of Mtap1b 8 0.45 1.04 0.16
97 INT335497 Positive_regulation of Protein_catabolism of Map2 1 0.32 0.61 0.16
98 INT94562 Negative_regulation of Regulation of Map2 1 0.43 1.12 0.12
99 INT128425 Negative_regulation of TPPP 1 0.07 1.42 0.12
100 INT355821 Regulation of Localization of NAV1 1 0.44 0.16 0.11
101 INT42713 Binding of CLIP1 2 0.36 0 0.1
102 INT46301 Positive_regulation of CLIP1 2 0.60 0 0.1
103 INT41525 Gene_expression of TPPP3 4 0.75 0.28 0.09
104 INT41524 Positive_regulation of Gene_expression of TPPP3 1 0.29 0 0.09
105 INT285260 Regulation of Positive_regulation of NAV1 1 0.21 0 0.08
106 INT102596 Negative_regulation of TPPP3 1 0.41 0.44 0.07
107 INT207609 Negative_regulation of Mtap1b 1 0.33 0.14 0.07
108 INT184742 Binding of MAP2 6 0.37 3.29 0.06
109 INT66352 Phosphorylation of CLIP1 2 0.63 0.88 0.05
110 INT199993 Phosphorylation of MAP2 1 0.79 0 0.05
111 INT204184 Localization of TPPP 3 0.23 1.65 0.03
112 INT308781 Regulation of TPPP 1 0.26 0.13 0.03
113 INT333110 Negative_regulation of Localization of TPPP 1 0.04 0.53 0.03
114 INT237226 Gene_expression of Plk1 3 0.59 0.78 0
115 INT204186 Positive_regulation of Gene_expression of TPPP 2 0.16 1.15 0
116 INT249774 Positive_regulation of Plk1 2 0.41 0.25 0
117 INT306280 Phosphorylation of TPPP 1 0.53 0.9 0
118 INT94755 Binding of Mtap7 1 0.31 0 0
119 INT204473 Transcription of Map1b 1 0.67 0.68 0
120 INT271928 Binding of Plk1 1 0.07 0.29 0
121 INT332370 Regulation of Plk1 1 0.21 0.13 0
122 INT236746 Regulation of Localization of Mtap2 1 0.08 0 0
123 INT332346 Phosphorylation of Plk1 1 0.62 0 0
124 INT207605 Negative_regulation of Gene_expression of Mtap1b 1 0.24 0 0
125 INT249761 Transcription of Plk1 1 0.60 0.12 0
126 INT245665 Positive_regulation of Phosphorylation of Mtap2 1 0.32 0.28 0
127 INT204445 Positive_regulation of Gene_expression of Mtap1b 1 0.37 0.66 0
128 INT337117 Gene_expression of CLIP1 1 0.13 0.08 0
129 INT249770 Positive_regulation of Gene_expression of Plk1 1 0.44 0.12 0
130 INT66349 Positive_regulation of Phosphorylation of CLIP1 1 0.36 0.78 0
131 INT184744 Regulation of Gene_expression of MAP2 1 0.45 0.92 0
132 INT204462 Transcription of Mtap1b 1 0.37 0.68 0
133 INT204456 Positive_regulation of Mtap1b 1 0.11 0.66 0
134 INT207603 Regulation of Localization of Mtap1b 1 0.25 0 0
135 INT332343 Positive_regulation of Phosphorylation of Plk1 1 0.38 0 0
136 INT328666 Regulation of Mtap2 1 0.20 0 0
137 INT92060 Localization of Mtap7 1 0.22 0.07 0
138 INT309070 Regulation of Gene_expression of Map2 1 0.11 0 0
139 INT271923 Regulation of Binding of Plk1 1 0.09 0.29 0
140 INT245667 Negative_regulation of Phosphorylation of Mtap2 1 0.27 0.13 0
141 INT92061 Phosphorylation of Mtap7 1 0.20 0.07 0
142 INT237227 Negative_regulation of Gene_expression of Plk1 1 0.08 0.54 0
143 INT309321 Negative_regulation of Gene_expression of MAP2 1 0.11 0.51 0
144 INT207607 Localization of Mtap1b 1 0.42 0 0
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