GO:0001588

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Name dopamine receptor activity, coupled via Gs
Categary Function
Go Slim No
Go Link GO:0001588
Unique Molecular Interactions 143
Total Molecular Interactions 193
Total Single Events 1493
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for dopamine receptor activity, coupled via Gs. They are ordered first by their pain relevance and then by number of times they were reported for dopamine receptor activity, coupled via Gs. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
2 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
3 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
4 INT70148 Drd1a Positive_regulation of Localization of Acot1 1 0.14 0 1.7
5 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35
6 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23
7 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
8 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
9 INT74185 Cck Negative_regulation of Drd1a 1 0.30 0.1 1.1
10 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01
11 INT87854 Binding of Drd1a and Positive_regulation of Localization of Abat 1 0.08 0 0.96
12 INT74184 Cck Regulation of Localization of Drd1a 1 0.32 0.06 0.95
13 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
14 INT136172 NPY Negative_regulation of Positive_regulation of Drd1a 1 0.21 0 0.91
15 INT7292 Binding of Drd1a and Penk 1 0.14 0 0.9
16 INT52760 Oprd1 Regulation of Drd1a 1 0.02 0 0.9
17 INT52762 Dll1 Regulation of Drd1a 1 0.10 0 0.89
18 INT29279 Binding of Drd1a and Htr1a 1 0.35 0.2 0.84
19 INT344101 Positive_regulation of Drd1a Positive_regulation of Localization of Abat 1 0.01 0 0.84
20 INT353721 Negative_regulation of Binding of Drd1a and Ghsr 1 0.16 0 0.76
21 INT353720 Binding of Drd1a and Ghsr 1 0.18 0 0.76
22 INT21260 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.05 0 0.76
23 INT327707 Binding of Comt and Drd1a 1 0.18 0.27 0.74
24 INT99938 Drd1a Regulation of Transcription of Qrfp 1 0.03 0 0.69
25 INT71988 Drd1a Regulation of Npr1 1 0.10 0 0.68
26 INT99939 Drd1a Regulation of Qrfp 1 0.03 0 0.68
27 INT317638 Ins1 Positive_regulation of Gene_expression of Drd1a 1 0.14 0.86 0.59
28 INT317634 Ins1 Positive_regulation of Drd1a 1 0.14 0.86 0.59
29 INT5111 DIO2 Positive_regulation of Drd1a 1 0.04 0 0.53
30 INT223925 Drd1a Positive_regulation of Gene_expression of Serpina1 1 0.01 0 0.51
31 INT184874 Drd1a Regulation of Gene_expression of Drd2 1 0.13 0.97 0.51
32 INT317635 Positive_regulation of Drd1a Positive_regulation of Phosphorylation of Gtf3a 1 0.01 0.53 0.43
33 INT331675 Binding of Drd1a and Sptan1 1 0.03 0.33 0.4
34 INT32244 Slc3a1 Positive_regulation of Localization of Drd1a 1 0.15 0 0.39
35 INT32243 Drd1a Positive_regulation of Localization of Slc3a1 1 0.15 0 0.39
36 INT344103 Positive_regulation of Drd1a Positive_regulation of Obfc1 1 0.00 0 0.38
37 INT37247 Binding of Drd1a and Drd2 1 0.20 0 0.37
38 INT327708 Binding of Drd1a and Drd2 1 0.12 0.12 0.37
39 INT258763 Binding of Drd5 and ADHD1 1 0.07 1.11 0.31
40 INT97595 Penk Regulation of Gene_expression of Drd1a 1 0.25 0.1 0.28
41 INT73385 Cfp Regulation of Drd1a 1 0.10 0 0.25
42 INT73384 Positive_regulation of Cfp Regulation of Drd1a 1 0.18 0 0.25
43 INT261465 Binding of Drd1a and Ptgdr 1 0.03 0.1 0.23
44 INT300563 Binding of Drd5 and ADHD1 1 0.01 1.13 0.19
45 INT294106 Binding of DNASE1L3 and DRD5 1 0.02 0 0.14
46 INT241070 Klf16 Positive_regulation of Drd1a 1 0.05 0.13 0.12
47 INT258756 Binding of Drd5 and Lmo1 1 0.03 0.64 0.08
48 INT261454 Akr1d1 Regulation of Drd1a 1 0.00 0.71 0.06
49 INT89016 Oprd1 Negative_regulation of Drd1a 1 0.06 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for dopamine receptor activity, coupled via Gs. They are ordered first by their pain relevance and then by number of times they were reported in dopamine receptor activity, coupled via Gs. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5858 Positive_regulation of Drd1a 66 0.69 4.51 51.73
2 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43
3 INT13838 Positive_regulation of Drd1a 48 0.70 9.83 23.42
4 INT7680 Regulation of Drd1a 27 0.45 4.52 18.86
5 INT51779 Gene_expression of Drd1a 46 0.66 11.18 17.51
6 INT7020 Negative_regulation of Drd1a 25 0.57 1.84 17.1
7 INT5859 Positive_regulation of Positive_regulation of Drd1a 20 0.55 2.05 15.61
8 INT7682 Binding of Drd1a 22 0.48 1.8 11.83
9 INT16735 Localization of Drd1a 11 0.61 0.35 8.42
10 INT22369 Negative_regulation of Drd1a 15 0.47 6.13 6.87
11 INT21552 Regulation of Drd1a 10 0.57 3.7 6.05
12 INT18366 Negative_regulation of Positive_regulation of Drd1a 6 0.42 0.49 5.54
13 INT101925 Binding of Drd1a 9 0.43 1.82 4.97
14 INT48567 Transcription of Drd1a 7 0.51 2.44 4.54
15 INT113078 Phosphorylation of Drd1a 4 0.30 0.77 4.45
16 INT13333 Regulation of Gene_expression of Drd1a 8 0.36 3.37 4.28
17 INT62901 Positive_regulation of Gene_expression of Drd1a 2 0.57 0.66 3.35
18 INT13335 Negative_regulation of Gene_expression of Drd1a 6 0.34 0.8 3.16
19 INT18365 Positive_regulation of Regulation of Drd1a 4 0.50 1.74 3.04
20 INT113077 Positive_regulation of Phosphorylation of Drd1a 1 0.11 0.15 2.87
21 INT64248 Positive_regulation of Positive_regulation of Drd1a 6 0.45 1.97 2.62
22 INT89992 Positive_regulation of Gene_expression of Drd1a 5 0.39 2.11 2.54
23 INT86462 Transcription of Drd1a 3 0.44 1.86 2.36
24 INT63394 Gene_expression of Drd5 7 0.76 1.85 2.3
25 INT24407 Negative_regulation of Binding of Drd1a 3 0.25 0.81 2.18
26 INT63392 Positive_regulation of Drd5 5 0.46 1.73 2.08
27 INT21046 Regulation of Positive_regulation of Drd1a 3 0.44 0.09 2.06
28 INT13837 Negative_regulation of Positive_regulation of Drd1a 2 0.43 1.43 2.01
29 INT140305 Negative_regulation of Binding of Drd1a 2 0.21 0.54 1.46
30 INT113079 Regulation of Phosphorylation of Drd1a 1 0.06 0.07 1.43
31 INT336571 Gene_expression of DRD5 1 0.06 0.73 1.41
32 INT103859 Positive_regulation of Drd5 2 0.49 0.81 1.14
33 INT103857 Gene_expression of Drd5 2 0.23 0.92 1.08
34 INT184839 Localization of Drd1a 4 0.73 0.84 1.03
35 INT63393 Positive_regulation of Gene_expression of Drd5 3 0.49 1.21 1.02
36 INT64690 Negative_regulation of Localization of Drd1a 2 0.09 0 0.95
37 INT74183 Positive_regulation of Localization of Drd1a 1 0.32 0.06 0.95
38 INT85999 Binding of Drd5 2 0.27 0.84 0.94
39 INT99668 Positive_regulation of Binding of Drd1a 2 0.43 0.89 0.87
40 INT300588 Regulation of Drd5 1 0.32 0.67 0.69
41 INT184846 Negative_regulation of Drd5 1 0.19 2.28 0.68
42 INT153157 Regulation of Regulation of Drd1a 2 0.25 0.2 0.66
43 INT184848 Positive_regulation of Transcription of Drd1a 1 0.26 0.93 0.65
44 INT140306 Regulation of Binding of Drd1a 1 0.20 0.36 0.64
45 INT72516 Regulation of Binding of Drd1a 2 0.44 0.4 0.63
46 INT103858 Regulation of Gene_expression of Drd5 1 0.08 0.92 0.58
47 INT157718 Binding of DRD5 1 0.33 0.57 0.52
48 INT344086 Binding of Drd5 1 0.36 0.06 0.37
49 INT48566 Regulation of Transcription of Drd1a 1 0.32 0 0.37
50 INT300593 Regulation of Gene_expression of Drd5 1 0.33 0.13 0.28
51 INT136052 Negative_regulation of Negative_regulation of Drd1a 1 0.13 0.66 0.27
52 INT223763 Negative_regulation of DRD5 1 0.01 0.06 0.06
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