GO:0001655

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Name urogenital system development
Categary Process
Go Slim No
Go Link GO:0001655
Unique Molecular Interactions 60
Total Molecular Interactions 69
Total Single Events 616
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for urogenital system development. They are ordered first by their pain relevance and then by number of times they were reported for urogenital system development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14
2 INT83804 Binding of EPHB3 and DRGX 1 0.00 0.62 0.62
3 INT120383 PRKCD Positive_regulation of Localization of EPHB2 1 0.29 0.42 0.52
4 INT108329 EGF Positive_regulation of Phosphorylation of EPHB2 4 0.48 3.96 0.48
5 INT278950 MAPK8 Negative_regulation of Localization of EPHB2 1 0.25 0.47 0.43
6 INT278964 MAPK14 Negative_regulation of Localization of EPHB2 1 0.15 0.47 0.43
7 INT309366 Pax2 Negative_regulation of Transcription of Slc6a5 1 0.03 0 0.31
8 INT309369 Ptf1a Positive_regulation of Pax2 1 0.10 0 0.3
9 INT296372 Binding of IDUA and ACD 1 0.03 2.72 0.23
10 INT222025 Gpx3 Regulation of EPHB2 1 0.01 1.41 0.18
11 INT198382 Binding of AR and SRD5A1 2 0.06 0.84 0.17
12 INT222877 Chrm2 Negative_regulation of EPHB2 1 0.05 0.66 0.17
13 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16
14 INT287890 THEMIS Regulation of Gene_expression of EPHB2 1 0.00 0.87 0.14
15 INT287883 FOS Regulation of Gene_expression of EPHB2 1 0.01 0.87 0.14
16 INT323430 Binding of Vhl and Osr1 1 0.02 0.78 0.13
17 INT326249 Prkcg Positive_regulation of EPHB2 1 0.06 0.63 0.13
18 INT326252 EPHB2 Positive_regulation of ras 1 0.03 0.62 0.13
19 INT291349 CXCR4 Positive_regulation of EPHB2 1 0.42 1.87 0.13
20 INT108330 EGF Negative_regulation of EPHB2 1 0.41 1.15 0.13
21 INT323434 Osr1 Regulation of Hif1a 1 0.01 0.79 0.13
22 INT323435 Binding of Osr1 and Gtf3a 1 0.00 0.78 0.13
23 INT323433 Osr1 Regulation of Protein_catabolism of Hif1a 1 0.01 0.8 0.13
24 INT280484 Bdnf Positive_regulation of Gene_expression of Lhx1 1 0.48 1.49 0.11
25 INT309371 Lhx1 Positive_regulation of Gene_expression of Pax2 1 0.08 0.07 0.11
26 INT309372 Lhx5 Positive_regulation of Gene_expression of Pax2 1 0.09 0.07 0.11
27 INT224021 PIK3CG Negative_regulation of EPHB2 1 0.03 0.5 0.09
28 INT224020 MAPK1 Negative_regulation of EPHB2 1 0.08 0.56 0.09
29 INT118416 Gata2 Positive_regulation of Transcription of Tac2 1 0.27 0.2 0.07
30 INT270786 Binding of AMH and CECR 1 0.10 0.12 0.06
31 INT218704 Mapk14 Regulation of EPHB2 1 0.01 0.33 0.05
32 INT218703 Mapk8 Regulation of EPHB2 1 0.04 0.33 0.05
33 INT216838 Binding of EPHB2 and Nfkb1 1 0.09 0.15 0.05
34 INT218705 Olr811 Regulation of EPHB2 1 0.01 0.32 0.05
35 INT218711 Olr811 Positive_regulation of Phosphorylation of EPHB2 1 0.02 0.33 0.03
36 INT333878 Shc1 Positive_regulation of EPHB2 1 0.08 0.3 0.03
37 INT233280 Binding of PBX1 and Emx2 1 0.19 0.68 0
38 INT244839 Lbx1 Positive_regulation of Pax2 1 0.39 0 0
39 INT293801 EGF Positive_regulation of EPHB2 1 0.11 0 0
40 INT233284 Regulation of Binding of PBX1 and Hoxa10 1 0.21 0.35 0
41 INT272977 Osr1 Regulation of ADHD1 1 0.01 1.79 0
42 INT293819 EPHB2 Positive_regulation of AR 1 0.23 0.12 0
43 INT233281 Binding of PBX1 and Hoxa10 1 0.28 0.35 0
44 INT272978 Binding of Osr1 and ADHD1 1 0.00 1.91 0
45 INT252888 Binding of SLC5A5 and PAX8 1 0.02 0.22 0
46 INT185453 Binding of PRKCB and Lhx1 1 0.35 1.99 0
47 INT244857 Lbx1 Positive_regulation of Lhx1 1 0.37 0 0
48 INT284892 AMH Regulation of Localization of FSHR 1 0.01 0.18 0
49 INT335022 Fgf15 Regulation of Pbx1 1 0.15 0.17 0
50 INT326197 Negative_regulation of HDAC9 Negative_regulation of EPHB2 1 0.17 0.15 0
51 INT297691 Binding of Fut1 and Pax2 1 0.03 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for urogenital system development. They are ordered first by their pain relevance and then by number of times they were reported in urogenital system development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21
2 INT87650 Positive_regulation of EPHB2 49 0.67 22.77 8.25
3 INT108336 Phosphorylation of EPHB2 41 0.80 22.25 8.21
4 INT125143 Gene_expression of EPHB2 40 0.71 13.27 6.97
5 INT108342 Negative_regulation of EPHB2 18 0.57 9.48 4.46
6 INT99889 Transcription of SRD5A1 5 0.71 1.45 3.74
7 INT117836 Gene_expression of EPHB3 13 0.29 0.62 3.44
8 INT16616 Negative_regulation of SRD5A1 44 0.57 34.81 2.96
9 INT108338 Positive_regulation of Phosphorylation of EPHB2 13 0.67 5.42 2.92
10 INT116077 Positive_regulation of Positive_regulation of EPHB2 4 0.67 2.32 2.13
11 INT342815 Positive_regulation of Transcription of SRD5A1 1 0.49 0.33 2.04
12 INT224501 Positive_regulation of Gene_expression of EPHB2 9 0.49 4.29 1.39
13 INT109924 Localization of EPHB2 6 0.73 2.07 1.28
14 INT198387 Regulation of SRD5A1 2 0.60 1.29 1.26
15 INT83805 Binding of EPHB3 1 0.00 1.15 1.19
16 INT108334 Negative_regulation of Phosphorylation of EPHB2 4 0.57 2.27 1.16
17 INT154493 Regulation of Gene_expression of SRD5A1 3 0.45 0.58 1.03
18 INT71601 Positive_regulation of ACD 11 0.60 6.55 0.9
19 INT312362 Gene_expression of PBX1 1 0.56 4.48 0.87
20 INT266556 Positive_regulation of AMH 9 0.70 4.33 0.82
21 INT312364 Positive_regulation of PBX1 1 0.43 4.69 0.81
22 INT109912 Positive_regulation of Localization of EPHB2 2 0.49 0.56 0.77
23 INT171747 Gene_expression of ACD 4 0.57 4.44 0.68
24 INT84826 Negative_regulation of ACD 6 0.50 4.02 0.55
25 INT278982 Regulation of EPHB2 6 0.44 1.97 0.53
26 INT125139 Regulation of Gene_expression of EPHB2 3 0.44 1.07 0.52
27 INT224498 Regulation of Positive_regulation of EPHB2 1 0.26 0.46 0.52
28 INT120403 Regulation of Phosphorylation of EPHB2 2 0.60 1.92 0.5
29 INT342811 Positive_regulation of Gene_expression of SRD5A1 1 0.45 0.22 0.5
30 INT127273 Gene_expression of AMH 24 0.78 9.53 0.47
31 INT217733 Negative_regulation of AMH 4 0.51 1.97 0.38
32 INT213507 Gene_expression of Pax2 10 0.67 1.41 0.34
33 INT278976 Negative_regulation of Gene_expression of EPHB2 1 0.41 0.51 0.32
34 INT312360 Positive_regulation of Gene_expression of PBX1 1 0.43 2 0.3
35 INT127274 Positive_regulation of Gene_expression of AMH 5 0.61 1.4 0.29
36 INT102992 Regulation of Negative_regulation of SRD5A1 4 0.60 3.59 0.29
37 INT309354 Regulation of Pax2 1 0.10 0 0.29
38 INT185428 Gene_expression of Lhx1 4 0.75 2.6 0.28
39 INT131265 Positive_regulation of Gene_expression of EPHB3 2 0.19 0 0.28
40 INT126059 Positive_regulation of Gata2 1 0.02 0.87 0.28
41 INT309339 Negative_regulation of Localization of Pax2 1 0.15 0 0.28
42 INT109932 Protein_catabolism of EPHB2 3 0.86 0.14 0.24
43 INT109923 Positive_regulation of Protein_catabolism of EPHB2 1 0.49 0.14 0.24
44 INT244742 Gene_expression of Gata2 2 0.54 0.18 0.23
45 INT353967 Positive_regulation of Gene_expression of Gata2 1 0.42 0.18 0.23
46 INT126794 Binding of SRD5A1 2 0.36 3.26 0.22
47 INT270788 Regulation of AMH 4 0.54 7.54 0.2
48 INT294915 Positive_regulation of Gene_expression of ACD 1 0.43 1.08 0.2
49 INT185427 Negative_regulation of Lhx1 4 0.42 3.48 0.17
50 INT159148 Localization of ACD 3 0.65 1.28 0.14
51 INT309352 Localization of Pax2 1 0.27 0 0.14
52 INT192056 Binding of Pbx1 2 0.31 0.46 0.13
53 INT329187 Positive_regulation of Positive_regulation of ACD 1 0.17 0.69 0.13
54 INT323417 Protein_catabolism of Osr1 1 0.07 0.84 0.13
55 INT236875 Localization of SRD5A1 2 0.73 0.8 0.11
56 INT294914 Positive_regulation of Localization of ACD 1 0.43 0.53 0.1
57 INT245059 Localization of PAX8 1 0.51 1.43 0.08
58 INT270857 Protein_catabolism of ACD 1 0.07 0.77 0.07
59 INT294075 Localization of AMH 2 0.70 0.59 0.06
60 INT294076 Positive_regulation of Localization of AMH 1 0.02 0.16 0.06
61 INT236876 Negative_regulation of Localization of SRD5A1 1 0.41 0.81 0.06
62 INT244741 Positive_regulation of Gene_expression of Pax2 1 0.38 0 0.06
63 INT162956 Binding of ACD 3 0.32 3.04 0.05
64 INT185429 Regulation of Lhx1 1 0.12 1.33 0.04
65 INT324622 Regulation of Gene_expression of AMH 1 0.39 0.51 0.04
66 INT323421 Gene_expression of Osr1 1 0.05 0.46 0.03
67 INT192055 Gene_expression of Pbx1 3 0.65 0.57 0
68 INT178534 Positive_regulation of SRD5A1 2 0.44 1.23 0
69 INT89749 Regulation of ACD 2 0.23 0.75 0
70 INT266558 Binding of AMH 2 0.08 0.47 0
71 INT236869 Negative_regulation of Negative_regulation of SRD5A1 2 0.41 2.68 0
72 INT272974 Negative_regulation of Gene_expression of Osr1 1 0.04 1.58 0
73 INT254038 Transcription of AMH 1 0.58 0.93 0
74 INT235653 Binding of EPHB2 1 0.08 1.04 0
75 INT294083 Negative_regulation of Gene_expression of AMH 1 0.02 0.74 0
76 INT185426 Binding of Lhx1 1 0.36 1.96 0
77 INT244782 Negative_regulation of Pax2 1 0.44 0 0
78 INT233212 Positive_regulation of Gene_expression of Pbx1 1 0.26 0.48 0
79 INT294916 Negative_regulation of Negative_regulation of ACD 1 0.36 0 0
80 INT294074 Regulation of Positive_regulation of AMH 1 0.02 0.9 0
81 INT233261 Binding of PBX1 1 0.35 0.34 0
82 INT326230 Regulation of Negative_regulation of EPHB2 1 0.44 0 0
83 INT272976 Regulation of Osr1 1 0.04 1.54 0
84 INT254037 Regulation of Transcription of AMH 1 0.50 0.45 0
85 INT272973 Gene_expression of Osr1 1 0.06 5.27 0
86 INT326234 Regulation of Protein_catabolism of EPHB2 1 0.44 0 0
87 INT233258 Negative_regulation of Binding of PBX1 1 0.42 0.34 0
88 INT254039 Positive_regulation of Transcription of AMH 1 0.56 0.47 0
89 INT213529 Negative_regulation of Gene_expression of Pax2 1 0.37 0.23 0
90 INT326236 Negative_regulation of Negative_regulation of EPHB2 1 0.41 0 0
91 INT272975 Negative_regulation of Osr1 1 0.05 1.51 0
92 INT294913 Negative_regulation of Gene_expression of ACD 1 0.36 0.14 0
93 INT266536 Negative_regulation of Protein_catabolism of EPHB2 1 0.41 0 0
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